Mutational signatures associated with tobacco smoking in human cancer

Science

Volumn 354, Issue 6312, 2016, Pages 618-622

  Alexandrov, Ludmil B ^a,b,c   Ju, Young Seok ^d   Haase, Kerstin ^e   Van Loo, Peter ^e,f   Martincorena, Iñigo ^g   Nik Zainal, Serena ^g,h   Totoki, Yasushi ⁱ   Fujimoto, Akihiro ^j,k   Nakagawa, Hidewaki ^j   Shibata, Tatsuhiro ^i,l   Campbell, Peter J ^g,m   Vineis, Paolo ^n,o   Phillips, David H ^p   Stratton, Michael R ^g  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b CENTER FOR NONLINEAR STUDIES   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^e THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^h ADDENBROOKE S HOSPITAL   (United Kingdom)

ⁱ NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^j RIKEN Center for Integrative Medical Sciences   (Japan)

^k KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^l UNIVERSITY OF TOKYO   (Japan)

^m UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁿ Human Genetics Foundation   (Italy)

^o PUBLIC HEALTH ENGLAND   (United Kingdom)

^p Imperial College London   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; DNA; TOBACCO SMOKE; APOLIPOPROTEIN B MRNA EDITING ENZYME CATALYTIC POLYPEPTIDE LIKE;

CANCER; CARCINOGEN; DNA; GENETIC ENGINEERING; HEALTH IMPACT; METHYLATION; MUTATION; PHYSIOLOGICAL RESPONSE; SMOKING; TOBACCO;

ARTICLE; CANCER RISK; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; EXOME; HUMAN; MAJOR CLINICAL STUDY; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; SMOKING; SOMATIC MUTATION; CHEMICALLY INDUCED; CPG ISLAND; GENETICS; METABOLISM; MUTATION; NEOPLASMS; RISK; TOBACCO; TOXICITY;

NICOTIANA TABACUM;

APOBEC DEAMINASES; CARCINOGENS; CPG ISLANDS; DNA DAMAGE; DNA METHYLATION; EXOME; HUMANS; MUTATION; NEOPLASMS; RISK; SMOKING; TOBACCO;

EID: 84994470617     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aag0299     Document Type: Article

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