-
1
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama, Y., Higuchi, M., Zhang, B., Huang, S.M., Iwata, N., Saido, T.C., Maeda, J., Suhara, T., Trojanowski, J.Q., Lee, V.M., Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53:3 (2007), 337–351, 10.1016/j.neuron.2007.01.010.
-
(2007)
Neuron
, vol.53
, Issue.3
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.10
-
2
-
-
0034940160
-
Neurodegenerative tauopathies
-
Lee, V.M., Goedert, M., Trojanowski, J.Q., Neurodegenerative tauopathies. Annu. Rev. Neurosci. 24 (2001), 1121–1159, 10.1146/annurev.neuro.24.1.1121.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1121-1159
-
-
Lee, V.M.1
Goedert, M.2
Trojanowski, J.Q.3
-
3
-
-
85011390798
-
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
-
DeVos, S.L., Miller, R.L., Schoch, K.M., Holmes, B.B., Kebodeaux, C.S., Wegener, A.J., Chen, G., Shen, T., Tran, H., Nichols, B., Zanardi, T.A., Kordasiewicz, H.B., Swayze, E.E., Bennett, C.F., Diamond, M.I., Miller, T.M., Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy. Sci. Transl. Med., 9(374), 2017, 10.1126/scitranslmed.aag0481.
-
(2017)
Sci. Transl. Med.
, vol.9
, Issue.374
-
-
DeVos, S.L.1
Miller, R.L.2
Schoch, K.M.3
Holmes, B.B.4
Kebodeaux, C.S.5
Wegener, A.J.6
Chen, G.7
Shen, T.8
Tran, H.9
Nichols, B.10
Zanardi, T.A.11
Kordasiewicz, H.B.12
Swayze, E.E.13
Bennett, C.F.14
Diamond, M.I.15
Miller, T.M.16
-
4
-
-
84970005269
-
Tau: from research to clinical development. Alzheimer's & dementia
-
Holtzman, D.M., Carrillo, M.C., Hendrix, J.A., Bain, L.J., Catafau, A.M., Gault, L.M., Goedert, M., Mandelkow, E., Mandelkow, E.M., Miller, D.S., Ostrowitzki, S., Polydoro, M., Smith, S., Wittmann, M., Hutton, M., Tau: from research to clinical development. Alzheimer's & dementia. J. Alzheimer's Assoc. 12:10 (2016), 1033–1039, 10.1016/j.jalz.2016.03.018.
-
(2016)
J. Alzheimer's Assoc.
, vol.12
, Issue.10
, pp. 1033-1039
-
-
Holtzman, D.M.1
Carrillo, M.C.2
Hendrix, J.A.3
Bain, L.J.4
Catafau, A.M.5
Gault, L.M.6
Goedert, M.7
Mandelkow, E.8
Mandelkow, E.M.9
Miller, D.S.10
Ostrowitzki, S.11
Polydoro, M.12
Smith, S.13
Wittmann, M.14
Hutton, M.15
-
5
-
-
0034672554
-
Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal
-
Perez, M., Cuadros, R., Smith, M.A., Perry, G., Avila, J., Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal. FEBS Lett. 486:3 (2000), 270–274.
-
(2000)
FEBS Lett.
, vol.486
, Issue.3
, pp. 270-274
-
-
Perez, M.1
Cuadros, R.2
Smith, M.A.3
Perry, G.4
Avila, J.5
-
6
-
-
0033836580
-
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification
-
Takeda, A., Smith, M.A., Avila, J., Nunomura, A., Siedlak, S.L., Zhu, X.W., Perry, G., Sayre, L.M., In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J. Neurochem. 75:3 (2000), 1234–1241, 10.1046/j.1471-4159.2000.0751234.x.
-
(2000)
J. Neurochem.
, vol.75
, Issue.3
, pp. 1234-1241
-
-
Takeda, A.1
Smith, M.A.2
Avila, J.3
Nunomura, A.4
Siedlak, S.L.5
Zhu, X.W.6
Perry, G.7
Sayre, L.M.8
-
7
-
-
0030898724
-
An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease
-
Lyras, L., Cairns, N.J., Jenner, A., Jenner, P., Halliwell, B., An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease. J. Neurochem. 68:5 (1997), 2061–2069.
-
(1997)
J. Neurochem.
, vol.68
, Issue.5
, pp. 2061-2069
-
-
Lyras, L.1
Cairns, N.J.2
Jenner, A.3
Jenner, P.4
Halliwell, B.5
-
8
-
-
34247564692
-
Role of iron in neurodegenerative disorders
-
Berg, D., Youdim, M.B., Role of iron in neurodegenerative disorders. Top. Magn. Reson. Imaging 17:1 (2006), 5–17, 10.1097/01.rmr.0000245461.90406.ad.
-
(2006)
Top. Magn. Reson. Imaging
, vol.17
, Issue.1
, pp. 5-17
-
-
Berg, D.1
Youdim, M.B.2
-
9
-
-
84907999177
-
The role of iron in brain ageing and neurodegenerative disorders
-
Ward, R.J., Zucca, F.A., Duyn, J.H., Crichton, R.R., Zecca, L., The role of iron in brain ageing and neurodegenerative disorders. Lancet Neurol. 13:10 (2014), 1045–1060, 10.1016/S1474-4422(14)70117-6.
-
(2014)
Lancet Neurol.
, vol.13
, Issue.10
, pp. 1045-1060
-
-
Ward, R.J.1
Zucca, F.A.2
Duyn, J.H.3
Crichton, R.R.4
Zecca, L.5
-
10
-
-
0027414336
-
Differences in microtubule binding and self-association abilities of bovine brain tau isoforms
-
Garcia de Ancos, J., Correas, I., Avila, J., Differences in microtubule binding and self-association abilities of bovine brain tau isoforms. J. Biol. Chem. 268:11 (1993), 7976–7982.
-
(1993)
J. Biol. Chem.
, vol.268
, Issue.11
, pp. 7976-7982
-
-
Garcia de Ancos, J.1
Correas, I.2
Avila, J.3
-
11
-
-
0029145757
-
Isolation of a phosphorylated soluble tau fraction from Alzheimer's disease brain
-
Ledesma, M.D., Avila, J., Correas, I., Isolation of a phosphorylated soluble tau fraction from Alzheimer's disease brain. Neurobiol. Aging 16:4 (1995), 515–522.
-
(1995)
Neurobiol. Aging
, vol.16
, Issue.4
, pp. 515-522
-
-
Ledesma, M.D.1
Avila, J.2
Correas, I.3
-
12
-
-
0036724204
-
Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease
-
Yamamoto, A., Shin, R.W., Hasegawa, K., Naiki, H., Sato, H., Yoshimasu, F., Kitamoto, T., Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. J. Neurochem. 82:5 (2002), 1137–1147.
-
(2002)
J. Neurochem.
, vol.82
, Issue.5
, pp. 1137-1147
-
-
Yamamoto, A.1
Shin, R.W.2
Hasegawa, K.3
Naiki, H.4
Sato, H.5
Yoshimasu, F.6
Kitamoto, T.7
-
13
-
-
0030989545
-
4-hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre, L.M., Zelasko, D.A., Harris, P.L.R., Perry, G., Salomon, R.G., Smith, M.A., 4-hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68:5 (1997), 2092–2097.
-
(1997)
J. Neurochem.
, vol.68
, Issue.5
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.R.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
14
-
-
0037448064
-
Prevention of oxidant-induced cell death by lysosomotropic iron chelators
-
Persson, H.L., Yu, Z., Tirosh, O., Eaton, J.W., Brunk, U.T., Prevention of oxidant-induced cell death by lysosomotropic iron chelators. Free Radic. Biol. Med. 34:10 (2003), 1295–1305.
-
(2003)
Free Radic. Biol. Med.
, vol.34
, Issue.10
, pp. 1295-1305
-
-
Persson, H.L.1
Yu, Z.2
Tirosh, O.3
Eaton, J.W.4
Brunk, U.T.5
-
15
-
-
38449099641
-
Alpha-lipoic acid as a new treatment option for Alzheimer's disease – a 48 months follow-up analysis
-
Hager, K., Kenklies, M., McAfoose, J., Engel, J., Munch, G., Alpha-lipoic acid as a new treatment option for Alzheimer's disease – a 48 months follow-up analysis. J. Neural Transm. Suppl. 72 (2007), 189–193.
-
(2007)
J. Neural Transm. Suppl.
, vol.72
, pp. 189-193
-
-
Hager, K.1
Kenklies, M.2
McAfoose, J.3
Engel, J.4
Munch, G.5
-
16
-
-
0034986275
-
Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia
-
Hager, K., Marahrens, A., Kenklies, M., Riederer, P., Munch, G., Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia. Arch. Gerontol. Geriatr. 32:3 (2001), 275–282.
-
(2001)
Arch. Gerontol. Geriatr.
, vol.32
, Issue.3
, pp. 275-282
-
-
Hager, K.1
Marahrens, A.2
Kenklies, M.3
Riederer, P.4
Munch, G.5
-
17
-
-
0037342554
-
The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
-
Farr, S.A., Poon, H.F., Dogrukol-Ak, D., Drake, J., Banks, W.A., Eyerman, E., Butterfield, D.A., Morley, J.E., The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J. Neurochem. 84:5 (2003), 1173–1183.
-
(2003)
J. Neurochem.
, vol.84
, Issue.5
, pp. 1173-1183
-
-
Farr, S.A.1
Poon, H.F.2
Dogrukol-Ak, D.3
Drake, J.4
Banks, W.A.5
Eyerman, E.6
Butterfield, D.A.7
Morley, J.E.8
-
18
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid
-
Liu, J., Head, E., Gharib, A.M., Yuan, W., Ingersoll, R.T., Hagen, T.M., Cotman, C.W., Ames, B.N., Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc. Natl. Acad. Sci. USA 99:4 (2002), 2356–2361, 10.1073/pnas.261709299.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.4
, pp. 2356-2361
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
Yuan, W.4
Ingersoll, R.T.5
Hagen, T.M.6
Cotman, C.W.7
Ames, B.N.8
-
19
-
-
33845442944
-
Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice
-
Quinn, J.F., Bussiere, J.R., Hammond, R.S., Montine, T.J., Henson, E., Jones, R.E., Stackman, R.W. Jr., Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol. Aging 28:2 (2007), 213–225, 10.1016/j.neurobiolaging.2005.12.014.
-
(2007)
Neurobiol. Aging
, vol.28
, Issue.2
, pp. 213-225
-
-
Quinn, J.F.1
Bussiere, J.R.2
Hammond, R.S.3
Montine, T.J.4
Henson, E.5
Jones, R.E.6
Stackman, R.W.7
-
20
-
-
84880444373
-
Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease
-
Sancheti, H., Akopian, G., Yin, F., Brinton, R.D., Walsh, J.P., Cadenas, E., Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease. PloS One, 8(7), 2013, e69830, 10.1371/journal.pone.0069830.
-
(2013)
PloS One
, vol.8
, Issue.7
, pp. e69830
-
-
Sancheti, H.1
Akopian, G.2
Yin, F.3
Brinton, R.D.4
Walsh, J.P.5
Cadenas, E.6
-
21
-
-
84895072006
-
Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study
-
Sancheti, H., Kanamori, K., Patil, I., Diaz Brinton, R., Ross, B.D., Cadenas, E., Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study. J. Cereb. Blood Flow. Metab.: Off. J. Int. Soc. Cereb. Blood Flow. Metab. 34:2 (2014), 288–296, 10.1038/jcbfm.2013.196.
-
(2014)
J. Cereb. Blood Flow. Metab.: Off. J. Int. Soc. Cereb. Blood Flow. Metab.
, vol.34
, Issue.2
, pp. 288-296
-
-
Sancheti, H.1
Kanamori, K.2
Patil, I.3
Diaz Brinton, R.4
Ross, B.D.5
Cadenas, E.6
-
22
-
-
0142010609
-
Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid
-
Lovell, M.A., Xie, C., Xiong, S., Markesbery, W.R., Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid. J. Alzheimer's Dis. 5:3 (2003), 229–239.
-
(2003)
J. Alzheimer's Dis.
, vol.5
, Issue.3
, pp. 229-239
-
-
Lovell, M.A.1
Xie, C.2
Xiong, S.3
Markesbery, W.R.4
-
23
-
-
32344435392
-
Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro
-
Ono, K., Hirohata, M., Yamada, M., Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro. Biochem. Biophys. Res. Commun. 341:4 (2006), 1046–1052, 10.1016/j.bbrc.2006.01.063.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.341
, Issue.4
, pp. 1046-1052
-
-
Ono, K.1
Hirohata, M.2
Yamada, M.3
-
24
-
-
84872146192
-
Direct and indirect antioxidant properties of alpha-lipoic acid and therapeutic potential
-
Rochette, L., Ghibu, S., Richard, C., Zeller, M., Cottin, Y., Vergely, C., Direct and indirect antioxidant properties of alpha-lipoic acid and therapeutic potential. Mol. Nutr. Food Res. 57:1 (2013), 114–125, 10.1002/mnfr.201200608.
-
(2013)
Mol. Nutr. Food Res.
, vol.57
, Issue.1
, pp. 114-125
-
-
Rochette, L.1
Ghibu, S.2
Richard, C.3
Zeller, M.4
Cottin, Y.5
Vergely, C.6
-
25
-
-
51449084024
-
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease
-
Maczurek, A., Hager, K., Kenklies, M., Sharman, M., Martins, R., Engel, J., Carlson, D.A., Munch, G., Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv. Drug Deliv. Rev. 60:13–14 (2008), 1463–1470, 10.1016/j.addr.2008.04.015.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, Issue.13-14
, pp. 1463-1470
-
-
Maczurek, A.1
Hager, K.2
Kenklies, M.3
Sharman, M.4
Martins, R.5
Engel, J.6
Carlson, D.A.7
Munch, G.8
-
26
-
-
34848890388
-
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts
-
Moreira, P.I., Harris, P.L., Zhu, X., Santos, M.S., Oliveira, C.R., Smith, M.A., Perry, G., Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J. Alzheimer's Dis. 12:2 (2007), 195–206.
-
(2007)
J. Alzheimer's Dis.
, vol.12
, Issue.2
, pp. 195-206
-
-
Moreira, P.I.1
Harris, P.L.2
Zhu, X.3
Santos, M.S.4
Oliveira, C.R.5
Smith, M.A.6
Perry, G.7
-
27
-
-
84871958441
-
Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
-
Guo, C., Wang, P., Zhong, M.L., Wang, T., Huang, X.S., Li, J.Y., Wang, Z.Y., Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochem. Int. 62:2 (2013), 165–172, 10.1016/j.neuint.2012.12.005.
-
(2013)
Neurochem. Int.
, vol.62
, Issue.2
, pp. 165-172
-
-
Guo, C.1
Wang, P.2
Zhong, M.L.3
Wang, T.4
Huang, X.S.5
Li, J.Y.6
Wang, Z.Y.7
-
28
-
-
84957429081
-
Ferroptosis: process and function
-
Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., Kang, R., Tang, D., Ferroptosis: process and function. Cell Death Differ. 23:3 (2016), 369–379, 10.1038/cdd.2015.158.
-
(2016)
Cell Death Differ.
, vol.23
, Issue.3
, pp. 369-379
-
-
Xie, Y.1
Hou, W.2
Song, X.3
Yu, Y.4
Huang, J.5
Sun, X.6
Kang, R.7
Tang, D.8
-
29
-
-
84861541814
-
Ferroptosis: an iron-dependent form of nonapoptotic cell death
-
Dixon, S.J., Lemberg, K.M., Lamprecht, M.R., Skouta, R., Zaitsev, E.M., Gleason, C.E., Patel, D.N., Bauer, A.J., Cantley, A.M., Yang, W.S., Morrison, B. 3rd, Stockwell, B.R., Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149:5 (2012), 1060–1072, 10.1016/j.cell.2012.03.042.
-
(2012)
Cell
, vol.149
, Issue.5
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
Patel, D.N.7
Bauer, A.J.8
Cantley, A.M.9
Yang, W.S.10
Morrison, B.11
Stockwell, B.R.12
-
30
-
-
84890922670
-
The role of iron and reactive oxygen species in cell death
-
Dixon, S.J., Stockwell, B.R., The role of iron and reactive oxygen species in cell death. Nat. Chem. Biol. 10:1 (2014), 9–17, 10.1038/nchembio.1416.
-
(2014)
Nat. Chem. Biol.
, vol.10
, Issue.1
, pp. 9-17
-
-
Dixon, S.J.1
Stockwell, B.R.2
-
31
-
-
85021836187
-
Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice
-
Zhang, S., Chai, R., Yang, Y.Y., Guo, S.Q., Wang, S., Guo, T., Xu, S.F., Zhang, Y.H., Wang, Z.Y., Guo, C., Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice. Oncotarget 8:27 (2017), 43617–43634, 10.18632/oncotarget.17116.
-
(2017)
Oncotarget
, vol.8
, Issue.27
, pp. 43617-43634
-
-
Zhang, S.1
Chai, R.2
Yang, Y.Y.3
Guo, S.Q.4
Wang, S.5
Guo, T.6
Xu, S.F.7
Zhang, Y.H.8
Wang, Z.Y.9
Guo, C.10
-
32
-
-
0038689162
-
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
-
Noble, W., Olm, V., Takata, K., Casey, E., O.M., Meyerson, J., Gaynor, K., LaFrancois, J., Wang, L.L., Kondo, T., Davies, P., Burns, M., Nixon, V.R., Dickson, D., Matsuoka, Y., Ahlijanian, M., Lau, L.F., Duff, K., Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron 38:4 (2003), 555–565, 10.1016/S0896-6273(03)00259-9.
-
(2003)
Neuron
, vol.38
, Issue.4
, pp. 555-565
-
-
Noble, W.1
Olm, V.2
Takata, K.3
Casey, E.O.M.4
Meyerson, J.5
Gaynor, K.6
LaFrancois, J.7
Wang, L.L.8
Kondo, T.9
Davies, P.10
Burns, M.11
Nixon, V.R.12
Dickson, D.13
Matsuoka, Y.14
Ahlijanian, M.15
Lau, L.F.16
Duff, K.17
-
33
-
-
33847214486
-
Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation
-
Rockenstein, E., Torrance, M., Adame, A., Mante, M., Bar-on, P., Rose, J.B., Crews, L., Masliah, E., Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. J. Neurosci. 27:8 (2007), 1981–1991, 10.1523/JNEUROSCI.4321-06.2007.
-
(2007)
J. Neurosci.
, vol.27
, Issue.8
, pp. 1981-1991
-
-
Rockenstein, E.1
Torrance, M.2
Adame, A.3
Mante, M.4
Bar-on, P.5
Rose, J.B.6
Crews, L.7
Masliah, E.8
-
34
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
Liu, F., Grundke-Iqbal, I., Iqbal, K., Gong, C.X., Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur. J. Neurosci. 22:8 (2005), 1942–1950, 10.1111/j.1460-9568.2005.04391.x.
-
(2005)
Eur. J. Neurosci.
, vol.22
, Issue.8
, pp. 1942-1950
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Gong, C.X.4
-
35
-
-
84874201513
-
Synaptic alterations in the rTg4510 mouse model of tauopathy
-
Kopeikina, K.J., Polydoro, M., Tai, H.C., Yaeger, E., Carlson, G.A., Pitstick, R., Hyman, B.T., Spires-Jones, T.L., Synaptic alterations in the rTg4510 mouse model of tauopathy. J. Comp. Neurol. 521:6 (2013), 1334–1353, 10.1002/cne.23234.
-
(2013)
J. Comp. Neurol.
, vol.521
, Issue.6
, pp. 1334-1353
-
-
Kopeikina, K.J.1
Polydoro, M.2
Tai, H.C.3
Yaeger, E.4
Carlson, G.A.5
Pitstick, R.6
Hyman, B.T.7
Spires-Jones, T.L.8
-
36
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
Ballatore, C., Lee, V.M.Y., Trojanowski, J.Q., Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 8:9 (2007), 663–672, 10.1038/nrn2194.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, Issue.9
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
-
37
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gomez-Isla, T., Hollister, R., West, H., Mui, S., Growdon, J.H., Petersen, R.C., Parisi, J.E., Hyman, B.T., Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 41:1 (1997), 17–24, 10.1002/ana.410410106.
-
(1997)
Ann. Neurol.
, vol.41
, Issue.1
, pp. 17-24
-
-
Gomez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
Parisi, J.E.7
Hyman, B.T.8
-
38
-
-
84911095292
-
Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice
-
Xu, H., Rosler, T.W., Carlsson, T., de Andrade, A., Bruch, J., Hollerhage, M., Oertel, W.H., Hoglinger, G.U., Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice. Neuropathol. Appl. Neurobiol. 40:7 (2014), 833–843, 10.1111/nan.12160.
-
(2014)
Neuropathol. Appl. Neurobiol.
, vol.40
, Issue.7
, pp. 833-843
-
-
Xu, H.1
Rosler, T.W.2
Carlsson, T.3
de Andrade, A.4
Bruch, J.5
Hollerhage, M.6
Oertel, W.H.7
Hoglinger, G.U.8
-
39
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz, K., Lewis, J., Spires, T., Paulson, J., Kotilinek, L., Ingelsson, M., Guimaraes, A., DeTure, M., Ramsden, M., McGowan, E., Forster, C., Yue, M., Orne, J., Janus, C., Mariash, A., Kuskowski, M., Hyman, B., Hutton, M., Ashe, K.H., Tau suppression in a neurodegenerative mouse model improves memory function. Science 309:5733 (2005), 476–481, 10.1126/science.1113694.
-
(2005)
Science
, vol.309
, Issue.5733
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
40
-
-
84955238343
-
TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice
-
Jiang, T., Zhang, Y.D., Chen, Q., Gao, Q., Zhu, X.C., Zhou, J.S., Shi, J.Q., Lu, H., Tan, L., Yu, J.T., TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice. Neuropharmacology 105 (2016), 196–206, 10.1016/j.neuropharm.2016.01.028.
-
(2016)
Neuropharmacology
, vol.105
, pp. 196-206
-
-
Jiang, T.1
Zhang, Y.D.2
Chen, Q.3
Gao, Q.4
Zhu, X.C.5
Zhou, J.S.6
Shi, J.Q.7
Lu, H.8
Tan, L.9
Yu, J.T.10
-
41
-
-
84899944338
-
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
-
Ahmed, Z., Cooper, J., Murray, T.K., Garn, K., McNaughton, E., Clarke, H., Parhizkar, S., Ward, M.A., Cavallini, A., Jackson, S., Bose, S., Clavaguera, F., Tolnay, M., Lavenir, I., Goedert, M., Hutton, M.L., O'Neill, M.J., A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathol. 127:5 (2014), 667–683, 10.1007/s00401-014-1254-6.
-
(2014)
Acta Neuropathol.
, vol.127
, Issue.5
, pp. 667-683
-
-
Ahmed, Z.1
Cooper, J.2
Murray, T.K.3
Garn, K.4
McNaughton, E.5
Clarke, H.6
Parhizkar, S.7
Ward, M.A.8
Cavallini, A.9
Jackson, S.10
Bose, S.11
Clavaguera, F.12
Tolnay, M.13
Lavenir, I.14
Goedert, M.15
Hutton, M.L.16
O'Neill, M.J.17
-
42
-
-
0026573467
-
Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study
-
Good, P.F., Perl, D.P., Bierer, L.M., Schmeidler, J., Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann. Neurol. 31:3 (1992), 286–292, 10.1002/ana.410310310.
-
(1992)
Ann. Neurol.
, vol.31
, Issue.3
, pp. 286-292
-
-
Good, P.F.1
Perl, D.P.2
Bierer, L.M.3
Schmeidler, J.4
-
43
-
-
0029789746
-
Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles
-
Smith, M.A., Sayre, L.M., Monnier, V.M., Perry, G., Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol. Chem. Neuropathol. 28:1–3 (1996), 41–48, 10.1007/BF02815203.
-
(1996)
Mol. Chem. Neuropathol.
, vol.28
, Issue.1-3
, pp. 41-48
-
-
Smith, M.A.1
Sayre, L.M.2
Monnier, V.M.3
Perry, G.4
-
44
-
-
84891373826
-
Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation
-
Crespo, A.C., Silva, B., Marques, L., Marcelino, E., Maruta, C., Costa, S., Timoteo, A., Vilares, A., Couto, F.S., Faustino, P., Correia, A.P., Verdelho, A., Porto, G., Guerreiro, M., Herrero, A., Costa, C., de Mendonca, A., Costa, L., Martins, M., Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation. Neurobiol. Aging 35:4 (2014), 777–785, 10.1016/j.neurobiolaging.2013.10.078.
-
(2014)
Neurobiol. Aging
, vol.35
, Issue.4
, pp. 777-785
-
-
Crespo, A.C.1
Silva, B.2
Marques, L.3
Marcelino, E.4
Maruta, C.5
Costa, S.6
Timoteo, A.7
Vilares, A.8
Couto, F.S.9
Faustino, P.10
Correia, A.P.11
Verdelho, A.12
Porto, G.13
Guerreiro, M.14
Herrero, A.15
Costa, C.16
de Mendonca, A.17
Costa, L.18
Martins, M.19
-
45
-
-
80051658907
-
Brain iron metabolism and its perturbation in neurological diseases
-
Crichton, R.R., Dexter, D.T., Ward, R.J., Brain iron metabolism and its perturbation in neurological diseases. J. Neural Transm. 118:3 (2011), 301–314, 10.1007/s00702-010-0470-z.
-
(2011)
J. Neural Transm.
, vol.118
, Issue.3
, pp. 301-314
-
-
Crichton, R.R.1
Dexter, D.T.2
Ward, R.J.3
-
46
-
-
84901425119
-
Methods to monitor ROS production by fluorescence microscopy and fluorometry
-
Wojtala, A., Bonora, M., Malinska, D., Pinton, P., Duszynski, J., Wieckowski, M.R., Methods to monitor ROS production by fluorescence microscopy and fluorometry. Methods Enzymol. 542 (2014), 243–262, 10.1016/B978-0-12-416618-9.00013-3.
-
(2014)
Methods Enzymol.
, vol.542
, pp. 243-262
-
-
Wojtala, A.1
Bonora, M.2
Malinska, D.3
Pinton, P.4
Duszynski, J.5
Wieckowski, M.R.6
-
47
-
-
84982840493
-
Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice
-
Xue, H., Chen, D., Zhong, Y.K., Zhou, Z.D., Fang, S.X., Li, M.Y., Guo, C., Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice. Ann. N. Y. Acad. Sci. 1375:1 (2016), 52–65, 10.1111/nyas.13174.
-
(2016)
Ann. N. Y. Acad. Sci.
, vol.1375
, Issue.1
, pp. 52-65
-
-
Xue, H.1
Chen, D.2
Zhong, Y.K.3
Zhou, Z.D.4
Fang, S.X.5
Li, M.Y.6
Guo, C.7
-
48
-
-
80355148410
-
Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice
-
Dumont, M., Stack, C., Elipenahli, C., Jainuddin, S., Gerges, M., Starkova, N.N., Yang, L., Starkov, A.A., Beal, F., Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice. FASEB J. 25:11 (2011), 4063–4072, 10.1096/fj.11-186650.
-
(2011)
FASEB J.
, vol.25
, Issue.11
, pp. 4063-4072
-
-
Dumont, M.1
Stack, C.2
Elipenahli, C.3
Jainuddin, S.4
Gerges, M.5
Starkova, N.N.6
Yang, L.7
Starkov, A.A.8
Beal, F.9
-
49
-
-
77953853456
-
The tau code
-
Avila, J., The tau code. Front Aging Neurosci., 1, 2009, 10.3389/neuro.24.001.2009.
-
(2009)
Front Aging Neurosci.
, vol.1
-
-
Avila, J.1
-
50
-
-
61849088424
-
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
-
Hanger, D.P., Anderton, B.H., Noble, W., Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 15:3 (2009), 112–119, 10.1016/j.molmed.2009.01.003.
-
(2009)
Trends Mol. Med.
, vol.15
, Issue.3
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
51
-
-
43249124363
-
Microtubule-associated protein tau in development, degeneration and protection of neurons
-
Wang, J.Z., Liu, F., Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog. Neurobiol. 85:2 (2008), 148–175, 10.1016/j.pneurobio.2008.03.002.
-
(2008)
Prog. Neurobiol.
, vol.85
, Issue.2
, pp. 148-175
-
-
Wang, J.Z.1
Liu, F.2
-
52
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal, K., Liu, F., Gong, C.X., Alonso Adel, C., Grundke-Iqbal, I., Mechanisms of tau-induced neurodegeneration. Acta Neuropathol. 118:1 (2009), 53–69, 10.1007/s00401-009-0486-3.
-
(2009)
Acta Neuropathol.
, vol.118
, Issue.1
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
53
-
-
0034088846
-
Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease
-
Gong, C.X., Lidsky, T., Wegiel, J., Zuck, L., Grundke-Iqbal, I., Iqbal, K., Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease. J. Biol. Chem. 275:8 (2000), 5535–5544.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.8
, pp. 5535-5544
-
-
Gong, C.X.1
Lidsky, T.2
Wegiel, J.3
Zuck, L.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
54
-
-
53749096967
-
Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
-
Vosler, P.S., Brennan, C.S., Chen, J., Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol. Neurobiol. 38:1 (2008), 78–100, 10.1007/s12035-008-8036-x.
-
(2008)
Mol. Neurobiol.
, vol.38
, Issue.1
, pp. 78-100
-
-
Vosler, P.S.1
Brennan, C.S.2
Chen, J.3
-
55
-
-
43049183420
-
Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells
-
Aggeli, I.K., Beis, I., Gaitanaki, C., Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells. Cell. Signal. 20:7 (2008), 1292–1302, 10.1016/j.cellsig.2008.02.019.
-
(2008)
Cell. Signal.
, vol.20
, Issue.7
, pp. 1292-1302
-
-
Aggeli, I.K.1
Beis, I.2
Gaitanaki, C.3
-
56
-
-
77951932919
-
Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease
-
Chang, K.H., de Pablo, Y., Lee, H.P., Lee, H.G., Smith, M.A., Shah, K., Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease. J. Neurochem. 113:5 (2010), 1221–1229, 10.1111/j.1471-4159.2010.06687.x.
-
(2010)
J. Neurochem.
, vol.113
, Issue.5
, pp. 1221-1229
-
-
Chang, K.H.1
de Pablo, Y.2
Lee, H.P.3
Lee, H.G.4
Smith, M.A.5
Shah, K.6
-
57
-
-
84982845464
-
Iron overload-induced calcium signals modulate mitochondrial fragmentation in HT-22 hippocampal neuron cells
-
Lee, D.G., Park, J., Lee, H.S., Lee, S.R., Lee, D.S., Iron overload-induced calcium signals modulate mitochondrial fragmentation in HT-22 hippocampal neuron cells. Toxicology 365 (2016), 17–24, 10.1016/j.tox.2016.07.022.
-
(2016)
Toxicology
, vol.365
, pp. 17-24
-
-
Lee, D.G.1
Park, J.2
Lee, H.S.3
Lee, S.R.4
Lee, D.S.5
-
58
-
-
33646519920
-
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
-
Spires, T.L., Orne, J.D., SantaCruz, K., Pitstick, R., Carlson, G.A., Ashe, K.H., Hyman, B.T., Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy. Am. J. Pathol. 168:5 (2006), 1598–1607, 10.2353/ajpath.2006.050840.
-
(2006)
Am. J. Pathol.
, vol.168
, Issue.5
, pp. 1598-1607
-
-
Spires, T.L.1
Orne, J.D.2
SantaCruz, K.3
Pitstick, R.4
Carlson, G.A.5
Ashe, K.H.6
Hyman, B.T.7
-
59
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen, B., Ingram, E., Takao, M., Smith, M.J., Jakes, R., Virdee, K., Yoshida, H., Holzer, M., Craxton, M., Emson, P.C., Atzori, C., Migheli, A., Crowther, R.A., Ghetti, B., Spillantini, M.G., Goedert, M., Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J. Neurosci. 22:21 (2002), 9340–9351.
-
(2002)
J. Neurosci.
, vol.22
, Issue.21
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
Atzori, C.11
Migheli, A.12
Crowther, R.A.13
Ghetti, B.14
Spillantini, M.G.15
Goedert, M.16
-
60
-
-
85012900626
-
Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
-
Hambright, W.S., Fonseca, R.S., Chen, L., Na, R., Ran, Q., Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration. Redox Biol. 12 (2017), 8–17, 10.1016/j.redox.2017.01.021.
-
(2017)
Redox Biol.
, vol.12
, pp. 8-17
-
-
Hambright, W.S.1
Fonseca, R.S.2
Chen, L.3
Na, R.4
Ran, Q.5
-
61
-
-
85032915286
-
MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells
-
Ito, K., Eguchi, Y., Imagawa, Y., Akai, S., Mochizuki, H., Tsujimoto, Y., MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells. Cell Death Discov., 3, 2017, 17013, 10.1038/cddiscovery.2017.13.
-
(2017)
Cell Death Discov.
, vol.3
, pp. 17013
-
-
Ito, K.1
Eguchi, Y.2
Imagawa, Y.3
Akai, S.4
Mochizuki, H.5
Tsujimoto, Y.6
-
62
-
-
67349276645
-
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases
-
Cahill, C.M., Lahiri, D.K., Huang, X., Rogers, J.T., Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases. Biochim. Biophys. Acta 1790:7 (2009), 615–628, 10.1016/j.bbagen.2008.12.001.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, Issue.7
, pp. 615-628
-
-
Cahill, C.M.1
Lahiri, D.K.2
Huang, X.3
Rogers, J.T.4
-
63
-
-
34249337528
-
Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents
-
Mandel, S., Amit, T., Bar-Am, O., Youdim, M.B., Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents. Prog. Neurobiol. 82:6 (2007), 348–360, 10.1016/j.pneurobio.2007.06.001.
-
(2007)
Prog. Neurobiol.
, vol.82
, Issue.6
, pp. 348-360
-
-
Mandel, S.1
Amit, T.2
Bar-Am, O.3
Youdim, M.B.4
-
64
-
-
85017015542
-
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
-
Ma, S., Henson, E.S., Chen, Y., Gibson, S.B., Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell Death Dis., 7, 2016, e2307, 10.1038/cddis.2016.208.
-
(2016)
Cell Death Dis.
, vol.7
, pp. e2307
-
-
Ma, S.1
Henson, E.S.2
Chen, Y.3
Gibson, S.B.4
-
65
-
-
84884900556
-
Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: from ferroptosis to stroke
-
Speer, R.E., Karuppagounder, S.S., Basso, M., Sleiman, S.F., Kumar, A., Brand, D., Smirnova, N., Gazaryan, I., Khim, S.J., Ratan, R.R., Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: from ferroptosis to stroke. Free Radic. Biol. Med. 62 (2013), 26–36, 10.1016/j.freeradbiomed.2013.01.026.
-
(2013)
Free Radic. Biol. Med.
, vol.62
, pp. 26-36
-
-
Speer, R.E.1
Karuppagounder, S.S.2
Basso, M.3
Sleiman, S.F.4
Kumar, A.5
Brand, D.6
Smirnova, N.7
Gazaryan, I.8
Khim, S.J.9
Ratan, R.R.10
-
66
-
-
85015710412
-
Iron addiction: a novel therapeutic target in ovarian cancer
-
Basuli, D., Tesfay, L., Deng, Z., Paul, B., Yamamoto, Y., Ning, G., Xian, W., McKeon, F., Lynch, M., Crum, C.P., Hegde, P., Brewer, M., Wang, X., Miller, L.D., Dyment, N., Torti, F.M., Torti, S.V., Iron addiction: a novel therapeutic target in ovarian cancer. Oncogene 36:29 (2017), 4089–4099, 10.1038/onc.2017.11.
-
(2017)
Oncogene
, vol.36
, Issue.29
, pp. 4089-4099
-
-
Basuli, D.1
Tesfay, L.2
Deng, Z.3
Paul, B.4
Yamamoto, Y.5
Ning, G.6
Xian, W.7
McKeon, F.8
Lynch, M.9
Crum, C.P.10
Hegde, P.11
Brewer, M.12
Wang, X.13
Miller, L.D.14
Dyment, N.15
Torti, F.M.16
Torti, S.V.17
-
67
-
-
85012272811
-
Lipid peroxidation in cell death
-
Gaschler, M.M., Stockwell, B.R., Lipid peroxidation in cell death. Biochem. Biophys. Res. Commun. 482:3 (2017), 419–425, 10.1016/j.bbrc.2016.10.086.
-
(2017)
Biochem. Biophys. Res. Commun.
, vol.482
, Issue.3
, pp. 419-425
-
-
Gaschler, M.M.1
Stockwell, B.R.2
-
68
-
-
34250372956
-
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
-
Yagoda, N., von Rechenberg, M., Zaganjor, E., Bauer, A.J., Yang, W.S., Fridman, D.J., Wolpaw, A.J., Smukste, I., Peltier, J.M., Boniface, J.J., Smith, R., Lessnick, S.L., Sahasrabudhe, S., Stockwell, B.R., RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 447:7146 (2007), 864–868, 10.1038/nature05859.
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 864-868
-
-
Yagoda, N.1
von Rechenberg, M.2
Zaganjor, E.3
Bauer, A.J.4
Yang, W.S.5
Fridman, D.J.6
Wolpaw, A.J.7
Smukste, I.8
Peltier, J.M.9
Boniface, J.J.10
Smith, R.11
Lessnick, S.L.12
Sahasrabudhe, S.13
Stockwell, B.R.14
-
69
-
-
85024121807
-
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
-
Yu, Y., Xie, Y., Cao, L., Yang, L., Yang, M., Lotze, M.T., Zeh, H.J., Kang, R., Tang, D., The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents. Mol. Cell. Oncol., 2(4), 2015, e1054549, 10.1080/23723556.2015.1054549.
-
(2015)
Mol. Cell. Oncol.
, vol.2
, Issue.4
, pp. e1054549
-
-
Yu, Y.1
Xie, Y.2
Cao, L.3
Yang, L.4
Yang, M.5
Lotze, M.T.6
Zeh, H.J.7
Kang, R.8
Tang, D.9
-
70
-
-
85015254073
-
Oncogene-selective sensitivity to synchronous cell death following modulation of the amino acid nutrient cystine
-
Poursaitidis, I., Wang, X., Crighton, T., Labuschagne, C., Mason, D., Cramer, S.L., Triplett, K., Roy, R., Pardo, O.E., Seckl, M.J., Rowlinson, S.W., Stone, E., Lamb, R.F., Oncogene-selective sensitivity to synchronous cell death following modulation of the amino acid nutrient cystine. Cell Rep. 18:11 (2017), 2547–2556, 10.1016/j.celrep.2017.02.054.
-
(2017)
Cell Rep.
, vol.18
, Issue.11
, pp. 2547-2556
-
-
Poursaitidis, I.1
Wang, X.2
Crighton, T.3
Labuschagne, C.4
Mason, D.5
Cramer, S.L.6
Triplett, K.7
Roy, R.8
Pardo, O.E.9
Seckl, M.J.10
Rowlinson, S.W.11
Stone, E.12
Lamb, R.F.13
|