-
1
-
-
0031012497
-
Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofi brillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau
-
Alonso, A. D., Grundke-Iqbal, I., Barra, H. S., and Iqbal, K. (1997). Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofi brillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau. Proc. Natl. Acad. Sci. U.S.A. 94, 298-303.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 298-303
-
-
Alonso, A.D.1
Grundke-Iqbal, I.2
Barra, H.S.3
Iqbal, K.4
-
2
-
-
0026488111
-
Structure and novel exons of the human tau gene
-
Andreadis, A., Brown, W. M., and Kosik, K. S. (1992). Structure and novel exons of the human tau gene. Biochemistry 31, 10626-10633.
-
(1992)
Biochemistry
, vol.31
, pp. 10626-10633
-
-
Andreadis, A.1
Brown, W.M.2
Kosik, K.S.3
-
3
-
-
17544393297
-
Tau dephosphorylation at tau-1 site correlates with its association to cell membrane
-
Arrasate, M., Perez, M., and Avila, J. (2000). Tau dephosphorylation at tau-1 site correlates with its association to cell membrane. Neurochem. Res. 25, 43-50.
-
(2000)
Neurochem. Res.
, vol.25
, pp. 43-50
-
-
Arrasate, M.1
Perez, M.2
Avila, J.3
-
4
-
-
1842415999
-
Role of glycosaminoglycans in determining the helicity of paired helical fi laments
-
Arrasate, M., Perez, M., Valpuesta, J. M., and Avila, J. (1997). Role of glycosaminoglycans in determining the helicity of paired helical fi laments. Am. J. Pathol. 151, 1115-1122.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1115-1122
-
-
Arrasate, M.1
Perez, M.2
Valpuesta, J.M.3
Avila, J.4
-
5
-
-
1642289188
-
Role of tau protein in both physiological and pathological conditions
-
Avila, J., Lucas, J. J., Perez, M., and Hernandez, F. (2004). Role of tau protein in both physiological and pathological conditions. Physiol. Rev. 84, 361-384.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
6
-
-
0342327346
-
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways
-
Barth, A. I., Nathke, I. S., and Nelson, W. J. (1997). Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9, 683-690.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 683-690
-
-
Barth, A.I.1
Nathke, I.S.2
Nelson, W.J.3
-
7
-
-
10944248857
-
Tau, tangles, and Alzheimer's disease
-
Binder, L. I., Guillozet-Bongaarts, A. L., Garcia-Sierra, F., and Berry, R. W. (2005). Tau, tangles, and Alzheimer's disease. Biochim. Biophys. Acta 1739, 216-223.
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
8
-
-
58149229648
-
Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy
-
Borroni, B., Malinverno, M., Gardoni, F., Alberici, A., Parnetti, L., Premi, E., Bonuccelli, U., Grassi, M., Perani, D., Calabresi, P., Di Luca, M., and Padovani, A. (2008). Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy. Neurology 71, 1796-1803.
-
(2008)
Neurology
, vol.71
, pp. 1796-1803
-
-
Borroni, B.1
Malinverno, M.2
Gardoni, F.3
Alberici, A.4
Parnetti, L.5
Premi, E.6
Bonuccelli, U.7
Grassi, M.8
Perani, D.9
Calabresi, P.10
Di Luca, M.11
Padovani, A.12
-
9
-
-
0028785525
-
Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
-
Brandt, R., Leger, J., and Lee, G. (1995). Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. J. Cell Biol. 131, 1327-1340.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1327-1340
-
-
Brandt, R.1
Leger, J.2
Lee, G.3
-
10
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buee, L., Bussiere, T., Buee-Scherrer, V., Delacourte, A., and Hof, P. R. (2000). Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Brain Res. Rev. 33, 95-130.
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
11
-
-
59649083175
-
Cortical defi - ciency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration
-
Chen, Z. L., Haegeli, V., Yu, H., and Strickland, S. (2009). Cortical defi - ciency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration. Dev. Biol. 327, 158-168.
-
(2009)
Dev. Biol.
, vol.327
, pp. 158-168
-
-
Chen, Z.L.1
Haegeli, V.2
Yu, H.3
Strickland, S.4
-
13
-
-
3242788650
-
Caspase-mediated degeneration in Alzheimer's disease
-
Cribbs, D. H., Poon, W. W., Rissman, R. A., and Blurton-Jones, M. (2004). Caspase-mediated degeneration in Alzheimer's disease. Am. J. Pathol. 165, 353-355.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 353-355
-
-
Cribbs, D.H.1
Poon, W.W.2
Rissman, R.A.3
Blurton-Jones, M.4
-
14
-
-
51349143580
-
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin
-
Cuchillo-Ibanez, I., Seereeram, A., Byers, H. L., Leung, K. Y., Ward, M. A., Anderton, B. H., and Hanger, D. P. (2008). Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin. FASEB J. 22, 3186-3195.
-
(2008)
FASEB J.
, vol.22
, pp. 3186-3195
-
-
Cuchillo-Ibanez, I.1
Seereeram, A.2
Byers, H.L.3
Leung, K.Y.4
Ward, M.A.5
Anderton, B.H.6
Hanger, D.P.7
-
15
-
-
48749126438
-
New application of beta-galactosidase complementation to monitor tau self-association
-
Ding, H., and Johnson, G. V. (2008). New application of beta-galactosidase complementation to monitor tau self-association. J. Neurochem. 106, 1545-1551.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1545-1551
-
-
Ding, H.1
Johnson, G.V.2
-
16
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
Dixit, R., Ross, J. L., Goldman, Y. E., and Holzbaur, E. L. (2008). Differential regulation of dynein and kinesin motor proteins by tau. Science 319, 1086-1089.
-
(2008)
Science
, vol.319
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.4
-
17
-
-
0022896901
-
Tau protein function in living cells
-
Drubin, D. G., and Kirschner, M. W. (1986). Tau protein function in living cells. J. Cell Biol. 103, 2739-2746.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2739-2746
-
-
Drubin, D.G.1
Kirschner, M.W.2
-
18
-
-
84890900396
-
{alpha}-Synuclein contributes to GSK-3{beta}-catalyzed Tau phosphorylation in Parkinson's disease models FASEB J. (in press). Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., and Mandelkow, E. (1998). Overexpression of tau protein inhibits kinesindependent traffi cking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
-
Duka, T., Duka, V., Joyce, J. N., and Sidhu, A. (2009). {alpha}-Synuclein contributes to GSK-3{beta}-catalyzed Tau phosphorylation in Parkinson's disease models. FASEB J. (in press). Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., and Mandelkow, E. (1998). Overexpression of tau protein inhibits kinesindependent traffi cking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J. Cell Biol. 143, 777-794.
-
(2009)
J. Cell Biol.
, vol.143
, pp. 777-794
-
-
Duka, T.1
Duka, V.2
Joyce, J.N.3
Sidhu, A.4
-
19
-
-
10944256690
-
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death
-
Feinstein, S. C., and Wilson, L. (2005). Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death. Biochim. Biophys. Acta 1739, 268-279.
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 268-279
-
-
Feinstein, S.C.1
Wilson, L.2
-
20
-
-
0041689948
-
Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
Gamblin, T. C., Chen, F., Zambrano, A., Abraha, A., Lagalwar, S., Guillozet, A. L., Lu, M., Fu, Y., Garcia-Sierra, F., LaPointe, N., Miller, R., Berry, R. W., Binder, L. I., and Cryns, V. L. (2003). Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 100, 10032-10037.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
21
-
-
59849124809
-
Altered splicing of Tau in DM1 is different from the foetal splicing process
-
Ghanem, D., Tran, H., Dhaenens, C. M., Schraen-Maschke, S., Sablonniere, B., Buee, L., Sergeant, N., and Caillet- Boudin, M. L. (2009). Altered splicing of Tau in DM1 is different from the foetal splicing process. FEBS Lett. 583, 675-679.
-
(2009)
FEBS Lett.
, vol.583
, pp. 675-679
-
-
Ghanem, D.1
Tran, H.2
Dhaenens, C.M.3
Schraen-Maschke, S.4
Sablonniere, B.5
Buee, L.6
Sergeant, N.7
Caillet-Boudin, M.L.8
-
22
-
-
0028885494
-
Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by prolinedirected protein kinases or cyclic AMP-dependent protein kinase
-
Goedert, M., Jakes, R., Qi, Z., Wang, J. H., and Cohen, P. (1995). Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by prolinedirected protein kinases or cyclic AMP-dependent protein kinase. J. Neurochem. 65, 2804-2807.
-
(1995)
J. Neurochem.
, vol.65
, pp. 2804-2807
-
-
Goedert, M.1
Jakes, R.2
Qi, Z.3
Wang, J.H.4
Cohen, P.5
-
23
-
-
0024387161
-
Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain
-
Goedert, M., Spillantini, M. G., Potier, M. C., Ulrich, J., and Crowther, R. A. (1989). Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J. 8, 393-399.
-
(1989)
EMBO J.
, vol.8
, pp. 393-399
-
-
Goedert, M.1
Spillantini, M.G.2
Potier, M.C.3
Ulrich, J.4
Crowther, R.A.5
-
24
-
-
33747862732
-
Extracellular tau is toxic to neuronal cells
-
Gomez-Ramos, A., Diaz-Hernandez, M., Cuadros, R., Hernandez, F., and Avila, J. (2006). Extracellular tau is toxic to neuronal cells. FEBS Lett. 580, 4842-4850.
-
(2006)
FEBS Lett.
, vol.580
, pp. 4842-4850
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Cuadros, R.3
Hernandez, F.4
Avila, J.5
-
25
-
-
41149111293
-
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
-
Gomez-Ramos, A., Diaz-Hernandez, M., Rubio, A., Miras-Portugal, M. T., and Avila, J. (2008). Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells. Mol. Cell. Neurosci. 37, 673-681.
-
(2008)
Mol. Cell. Neurosci.
, vol.37
, pp. 673-681
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Rubio, A.3
Miras-Portugal, M.T.4
Avila, J.5
-
26
-
-
0028064431
-
Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase- 2A
-
Gong, C. X., Grundke-Iqbal, I., and Iqbal, K. (1994a). Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase- 2A. Neuroscience 61, 765-772.
-
(1994)
Neuroscience
, vol.61
, pp. 765-772
-
-
Gong, C.X.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
27
-
-
0034088846
-
Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain
-
Gong, C. X., Lidsky, T., Wegiel, J., Zuck, L., Grundke-Iqbal, I., and Iqbal, K. (2000). Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofi brillary degeneration in Alzheimer's disease. J. Biol. Chem. 275, 5535-5544.
-
(2000)
Implications for neurofi brillary degeneration in Alzheimer's disease. J. Biol. Chem.
, vol.275
, pp. 5535-5544
-
-
Gong, C.X.1
Lidsky, T.2
Wegiel, J.3
Zuck, L.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
28
-
-
0028044722
-
Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase-2B (calcineurin)
-
Gong, C. X., Singh, T. J., Grundke-Iqbal, I., and Iqbal, K. (1994b). Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase-2B (calcineurin). J. Neurochem. 62, 803-806.
-
(1994)
J. Neurochem
, vol.62
, pp. 803-806
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
29
-
-
0031035402
-
Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly
-
Goode, B. L., Denis, P. E., Panda, D., Radeke, M. J., Miller, H. P., Wilson, L., and Feinstein, S. C. (1997). Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly. Mol. Biol. Cell 8, 353-365.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 353-365
-
-
Goode, B.L.1
Denis, P.E.2
Panda, D.3
Radeke, M.J.4
Miller, H.P.5
Wilson, L.6
Feinstein, S.C.7
-
30
-
-
0033591225
-
5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10
-
Grover, A., Houlden, H., Baker, M., Adamson, J., Lewis, J., Prihar, G., Pickering-Brown, S., Duff, K., and Hutton, M. (1999). 5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. J. Biol. Chem. 274, 15134-15143.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15134-15143
-
-
Grover, A.1
Houlden, H.2
Baker, M.3
Adamson, J.4
Lewis, J.5
Prihar, G.6
Pickering-Brown, S.7
Duff, K.8
Hutton, M.9
-
31
-
-
61849088424
-
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
-
Hanger, D. P., Anderton, B. H., and Noble, W. (2009). Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 15, 112-119.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
32
-
-
0345276564
-
GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms
-
Hernandez, F., Lucas, J. J., Cuadros, R., and Avila, J. (2003). GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms. Neurobiol. Aging 24, 1087-1094.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 1087-1094
-
-
Hernandez, F.1
Lucas, J.J.2
Cuadros, R.3
Avila, J.4
-
33
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton, M., Lendon, C. L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering- Brown, S., Chakraverty, S., Isaacs, A., Grover, A., Hackett, J., Adamson, J., Lincoln, S., Dickson, D., Davies, P., Petersen, R. C., Stevens, M., de Graaff, E., Wauters, E., van Baren, J., Hillebrand, M., Joosse, M., Kwon, J. M., Nowotny, P., Che, L. K., Norton, J., Morris, J. C., Reed, L. A., Trojanowski, J., Basun, H., Lannfelt, L., Neystat, M., Fahn, S., Dark, F., Tannenberg, T., Dodd, P. R., Hayward, N., Kwok, J. B., Schofi eld, P. R., Andreadis, A., Snowden, J., Craufurd, D., Neary, D., Owen, F., Oostra, B. A., Hardy, J., Goate, A., van Swieten, J., Mann, D., Lynch, T., and Heutink, P. (1998). Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393, 702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebr, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Che, L.K.25
Norton, J.26
Morris, J.C.27
Reed, L.A.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.R.36
Hayward, N.37
Kwok, J.B.38
Schofield, P.R.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Oostra, B.A.45
Hardy, J.46
Goate, A.47
Van Swieten, J.48
Mann, D.49
Lynch, T.50
Heutink, P.51
more..
-
34
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T., and Allis, C. D. (2001). Translating the histone code. Science 293, 1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
35
-
-
37049048544
-
Paired helical fi laments in electron microscopy of Alzheimer's disease
-
Kidd, M. (1963). Paired helical fi laments in electron microscopy of Alzheimer's disease. Nature 197, 192-193.
-
(1963)
Nature
, vol.197
, pp. 192-193
-
-
Kidd, M.1
-
36
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
Lee, G., Cowan, N., and Kirschner, M. (1988). The primary structure and heterogeneity of tau protein from mouse brain. Science 239, 285-288.
-
(1988)
Science
, vol.239
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
37
-
-
12144288564
-
Phosphorylation of tau by fyn: implications for Alzheimer's disease
-
Lee, G., Thangavel, R., Sharma, V. M., Litersky, J. M., Bhaskar, K., Fang, S. M., Do, L. H., Andreadis, A., Van Hoesen, G., and Ksiezak-Reding, H. (2004). Phosphorylation of tau by fyn: implications for Alzheimer's disease. J. Neurosci. 24, 2304-2312.
-
(2004)
J. Neurosci.
, vol.24
, pp. 2304-2312
-
-
Lee, G.1
Thangavel, R.2
Sharma, V.M.3
Litersky, J.M.4
Bhaskar, K.5
Fang, S.M.6
Do, L.H.7
Andreadis, A.8
Van Hoesen, G.9
Ksiezak-Reding, H.10
-
38
-
-
0034940160
-
Neurodegenerative tauopathies
-
Lee, V. M., Goedert, M., and Tro j a n ow s k i, J. Q. (2 0 0 1). Neurodegenerative tauopathies. Annu. Rev. Neurosci. 24, 1121-1159.
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 1121-1159
-
-
Lee, V.M.1
Goedert, M.2
Trojanowski, J.Q.3
-
39
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
Lu, P. J., Wulf, G., Zhou, X. Z., Davies, P., and Lu, K. P. (1999). The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 399, 784-788.
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
40
-
-
40549124991
-
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
-
Mondragon-Rodriguez, S., Basurto- Islas, G., Santa-Maria, I., Mena, R., Binder, L. I., Avila, J., Smith, M. A., Perry, G., and Garcia-Sierra, F. (2008). Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int. J. Exp. Pathol. 89, 81-90.
-
(2008)
Int. J. Exp. Pathol.
, vol.89
, pp. 81-90
-
-
Mondragon-Rodriguez, S.1
Basurto-Islas, G.2
Santa-Maria, I.3
Mena, R.4
Binder, L.I.5
Avila, J.6
Smith, M.A.7
Perry, G.8
Garcia-Sierra, F.9
-
41
-
-
0028899714
-
Prolinedirected and non- proline-directed phosphorylation of PHF-tau
-
Morishima-Kawashima, M., Hasegawa, M., Takio, K., Suzuki, M., Yoshida, H., Titani, K., and Ihara, Y. (1995). Prolinedirected and non- proline-directed phosphorylation of PHF-tau. J. Biol. Chem. 270, 823-829.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 823-829
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Titani, K.6
Ihara, Y.7
-
42
-
-
0022827447
-
Identifi cation of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule- associated protein 2
-
Neve, R. L., Harris, P., Kosik, K. S., Kurnit, D. M., and Donlon, T. A. (1986). Identifi cation of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule- associated protein 2. Brain Res. 387, 271-280.
-
(1986)
Brain Res.
, vol.387
, pp. 271-280
-
-
Neve, R.L.1
Harris, P.2
Kosik, K.S.3
Kurnit, D.M.4
Donlon, T.A.5
-
43
-
-
0346220382
-
The possible role of myelin destruction as a precipitating event in Alzheimer's disease
-
Noble, M. (2004). The possible role of myelin destruction as a precipitating event in Alzheimer's disease. Neurobiol. Aging 25, 25-31.
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 25-31
-
-
Noble, M.1
-
44
-
-
20044370830
-
The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates betaamyloid- induced neurodegeneration
-
Park, S. Y., and Ferreira, A. (2005). The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates betaamyloid- induced neurodegeneration. J. Neurosci. 25, 5365-5375.
-
(2005)
J. Neurosci.
, vol.25
, pp. 5365-5375
-
-
Park, S.Y.1
Ferreira, A.2
-
45
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick, G. N., Zukerberg, L., Nikolic, M., de la Monte, S., Dikkes, P., and Tsai, L. H. (1999). Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402, 615-622.
-
(1999)
Nature
, vol.402
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De la Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
46
-
-
65949122957
-
Tau-an inhibitor of deacetylase HDAC6 function
-
Perez, M., Santa-Maria, I., de Barreda, E. G., Zhu, X., Cuadros, R., Cabrero, J. R., Sanchez-Madrid, F., Dawson, H. N., Vitek, M. P., Perry, G., Smith, M. A., and Avila, J. (2009). Tau-an inhibitor of deacetylase HDAC6 function. J. Neurochem. 109, 1756-1766.
-
(2009)
J. Neurochem.
, vol.109
, pp. 1756-1766
-
-
Perez, M.1
Santa-Maria, I.2
De Barreda, E.G.3
Zhu, X.4
Cuadros, R.5
Cabrero, J.R.6
Sanchez-Madrid, F.7
Dawson, H.N.8
Vitek, M.P.9
Perry, G.10
Smith, M.A.11
Avila, J.12
-
47
-
-
0343336439
-
Ferritin is associated with the aberrant tau fi laments present in progressive supranuclear palsy
-
Perez, M., Valpuesta, J. M., de Garcini, E. M., Quintana, C., Arrasate, M., Lopez Carrascosa, J. L., Rabano, A., Garcia de Yebenes, J., and Avila, J. (1998). Ferritin is associated with the aberrant tau fi laments present in progressive supranuclear palsy. Am. J. Pathol. 152, 1531-1539.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 1531-1539
-
-
Perez, M.1
Valpuesta, J.M.2
de Garcini, E.M.3
Quintana, C.4
Arrasate, M.5
Lopez Carrascosa, J.L.6
Rabano, A.7
Garcia de Yebenes, J.8
Avila, J.9
-
48
-
-
67650556426
-
Caspase-cleaved tau expression results in mitochondrial dysfunction in cortical neurons
-
Quintanilla, R. A., Matthews- Roberson, T. A., Dolan, P. J., and Johnson, G. V. (2009). Caspase-cleaved tau expression results in mitochondrial dysfunction in cortical neurons. Implications for the pathogenesis of Alzheimer disease. J. Biol. Chem. 284, 18754-18766.
-
(2009)
Implications for the pathogenesis of Alzheimer disease. J. Biol. Chem.
, vol.284
, pp. 18754-18766
-
-
Quintanilla, R.A.1
Matthews-Roberson, T.A.2
Dolan, P.J.3
Johnson, G.V.4
-
49
-
-
3242749074
-
Caspasecleavage of tau is an early event in Alzheimer disease tangle pathology
-
Rissman, R. A., Poon, W. W., Blurton- Jones, M., Oddo, S., Torp, R., Vitek, M. P., LaFerla, F. M., Rohn, T. T., and Cotman, C. W. (2004). Caspasecleavage of tau is an early event in Alzheimer disease tangle pathology. J. Clin. Invest. 114, 121-130.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
Vitek, M.P.6
LaFerla, F.M.7
Rohn, T.T.8
Cotman, C.W.9
-
50
-
-
64949087565
-
Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3zeta protein
-
Sadik, G., Tanaka, T., Kato, K., Yanagi, K., Kudo, T., and Takeda, M. (2009). Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3zeta protein. Biochem. Biophys. Res. Commun. 383, 37-41.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.383
, pp. 37-41
-
-
Sadik, G.1
Tanaka, T.2
Kato, K.3
Yanagi, K.4
Kudo, T.5
Takeda, M.6
-
51
-
-
12144289142
-
Quinones facilitate the selfassembly of the phosphorylated tubulin binding region of tau into fibrillar polymers
-
Santa-Maria, I., Hernandez, F., Martin, C. P., Avila, J., and Moreno, F. J. (2004). Quinones facilitate the selfassembly of the phosphorylated tubulin binding region of tau into fibrillar polymers. Biochemistry 43, 2888-2897.
-
(2004)
Biochemistry
, vol.43
, pp. 2888-2897
-
-
Santa-Maria, I.1
Hernandez, F.2
Martin, C.P.3
Avila, J.4
Moreno, F.J.5
-
52
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical fi laments
-
Schneider, A., Biernat, J., von Bergen, M., Mandelkow, E., and Mandelkow, E. M. (1999). Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical fi laments. Biochemistry 38, 3549-3558.
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
Von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
53
-
-
0021673482
-
Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly
-
Serrano, L., de la Torre, J., Maccioni, R. B., and Avila, J. (1984). Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly. Proc. Natl. Acad. Sci. U.S.A. 81, 5989-5993.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 5989-5993
-
-
Serrano, L.1
De la Torre, J.2
Maccioni, R.B.3
Avila, J.4
-
54
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini, M. G., Murrell, J. R., Goedert, M., Farlow, M. R., Klug, A., and Ghetti, B. (1998). Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl. Acad. Sci. U.S.A. 95, 7737-7741.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
55
-
-
0034610814
-
The language of covalent histone modifi cations
-
Strahl, B. D., and Allis, C. D. (2000). The language of covalent histone modifi cations. Nature 403, 41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
56
-
-
0033529304
-
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
-
Varani, L., Hasegawa, M., Spillantini, M. G., Smith, M. J., Murrell, J. R., Ghetti, B., Klug, A., Goedert, M., and Varani, G. (1999). Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proc. Natl. Acad. Sci. U.S.A. 96, 8229-8234.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 8229-8234
-
-
Varani, L.1
Hasegawa, M.2
Spillantini, M.G.3
Smith, M.J.4
Murrell, J.R.5
Ghetti, B.6
Klug, A.7
Goedert, M.8
Varani, G.9
-
57
-
-
43249124363
-
Microtubuleassociated protein tau in development, degeneration and protection of neurons
-
Wang, J. Z., and Liu, F. (2008). Microtubuleassociated protein tau in development, degeneration and protection of neurons. Prog. Neurobiol. 85, 148-175.
-
(2008)
Prog. Neurobiol.
, vol.85
, pp. 148-175
-
-
Wang, J.Z.1
Liu, F.2
-
58
-
-
0008538685
-
A protein factor essential for microtubule assembly
-
Weingarten, M. D., Lockwood, A. H., Hwo, S. Y., and Kirschner, M. W. (1975). A protein factor essential for microtubule assembly. Proc. Natl. Acad. Sci. U.S.A. 72, 1858-1862.
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 1858-1862
-
-
Weingarten, M.D.1
Lockwood, A.H.2
Hwo, S.Y.3
Kirschner, M.W.4
-
59
-
-
50849110525
-
p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease
-
Wetzel, M. K., Naska, S., Laliberte, C. L., Rymar, V. V., Fujitani, M., Biernaskie, J. A., Cole, C. J., Lerch, J. P., Spring, S., Wang, S. H., Frankland, P. W., Henkelman, R. M., Josselyn, S. A., Sadikot, A. F., Miller, F. D., and Kaplan, D. R. (2008). p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease. Neuron 59, 708-721.
-
(2008)
Neuron
, vol.59
, pp. 708-721
-
-
Wetzel, M.K.1
Naska, S.2
Laliberte, C.L.3
Rymar, V.V.4
Fujitani, M.5
Biernaskie, J.A.6
Cole, C.J.7
Lerch, J.P.8
Spring, S.9
Wang, S.H.10
Frankl, P.W.11
Henkelman, R.M.12
Josselyn, S.A.13
Sadikot, A.F.14
Miller, F.D.15
Kaplan, D.R.16
-
60
-
-
0002009849
-
-
Modelling prion-like processing of tau protein in Alzheimer's disease for pharmaceutical development. In Brain Microtubule Associated, J. Avila, R. Brandt, and K.S. Koskik, eds (Chur, Switzerland, Harwood Academic)
-
Wischik, C. M., Lai, R. Y. K., and Harrington, C.R. (1997). Modelling prion-like processing of tau protein in Alzheimer's disease for pharmaceutical development. In Brain Microtubule Associated, J. Avila, R. Brandt, and K.S. Koskik, eds (Chur, Switzerland, Harwood Academic), pp 185-241.
-
(1997)
, pp. 185-241
-
-
Wischik, C.M.1
Lai, R.Y.K.2
Harrington, C.R.3
-
61
-
-
44649100169
-
Direct analysis of tau from PSP brain identifi es new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats
-
Wray, S., Saxton, M., Anderton, B. H., and Hanger, D. P. (2008). Direct analysis of tau from PSP brain identifi es new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats. J. Neurochem. 105, 2343-2352.
-
(2008)
J. Neurochem.
, vol.105
, pp. 2343-2352
-
-
Wray, S.1
Saxton, M.2
Anderton, B.H.3
Hanger, D.P.4
-
62
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
Yuan, A., Kumar, A., Peterhoff, C., Duff, K., and Nixon, R. A. (2008). Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J. Neurosci. 28, 1682-1687.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
|