-
1
-
-
84897381734
-
-
IARC CancerBase 2014, 11. ISBN-13 978-92-832-2447-1. IARC. Available online, accessed on 29 September 2017
-
Ferlay, J., Soerjomataram, I., Ervik, M., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D.M., Forman, D., Bray, F. GLOBOCAN 2012: Estimated cancer incidence, mortality and prevalence worldwide in 2012 v1.0. IARC CancerBase 2014, 11. ISBN-13 978-92-832-2447-1. IARC. Available online: http://publications.iarc.fr/Databases/Iarc-Cancerbases/Globocan-2012-Estimated-Cancer-Incidence- Mortality-And-Prevalence-Worldwide-In-2012-V1-0-2012 (accessed on 29 September 2017).
-
(2012)
Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012 V1.0
-
-
Ferlay, J.1
Soerjomataram, I.2
Ervik, M.3
Dikshit, R.4
Eser, S.5
Mathers, C.6
Rebelo, M.7
Parkin, D.M.8
Forman, D.9
Bray, F.10
-
2
-
-
84939979930
-
Impact of breast cancer subtypes and patterns of metastasis on outcome. Breast Cancer Res
-
Kast, K., Link, T., Friedrich, K., Petzold, A., Niedostatek, A., Schoffer, O., Werner, C., Klug, S.J., Werner, A., Gatzweiler, A., et al. Impact of breast cancer subtypes and patterns of metastasis on outcome. Breast Cancer Res. Treat. 2015, 150, 621–629.
-
(2015)
Treat
, vol.150
, pp. 621-629
-
-
Kast, K.1
Link, T.2
Friedrich, K.3
Petzold, A.4
Niedostatek, A.5
Schoffer, O.6
Werner, C.7
Klug, S.J.8
Werner, A.9
Gatzweiler, A.10
-
3
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.
-
Lehmann, B.D., Bauer, J.A., Chen, X., Sanders, M.E., Chakravarthy, A.B., Shyr, Y., Pietenpol, J.A. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J. Clin. Investig. 2011, 121, 2750–2767.
-
(2011)
Treat
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
Shyr, Y.6
Pietenpol, J.A.7
-
4
-
-
84927621560
-
Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer. Clin
-
Burstein, M.D., Tsimelzon, A., Poage, G.M., Covington, K.R., Contreras, A., Fuqua, S.A., Savage, M.I., Osborne, C.K., Hilsenbeck, S.G., Chang, J.C., et al. Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer. Clin. Cancer Res. 2015, 21, 1688–1698.
-
(2015)
Cancer Res
, vol.21
, pp. 1688-1698
-
-
Burstein, M.D.1
Tsimelzon, A.2
Poage, G.M.3
Covington, K.R.4
Contreras, A.5
Fuqua, S.A.6
Savage, M.I.7
Osborne, C.K.8
Hilsenbeck, S.G.9
Chang, J.C.10
-
5
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012, 490, 61–70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
6
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat, A., Parker, J.S., Karginova, O., Fan, C., Livasy, C., Herschkowitz, J.I., He, X., Perou, C.M. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res. 2010, 12, R68.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
He, X.7
Perou, C.M.8
-
7
-
-
68349150810
-
Mammary development meets cancer genomics.
-
Prat, A., Perou, C.M. Mammary development meets cancer genomics. Nat. Med. 2009, 15, 842–844.
-
(2009)
Nat. Med
, vol.15
, pp. 842-844
-
-
Prat, A.1
Perou, C.M.2
-
8
-
-
85114283387
-
EMT in breast carcinoma-A review
-
Felipe Lima, J., Nofech-Mozes, S., Bayani, J., Bartlett, J.M. EMT in breast carcinoma-A review. J. Clin. Med. 2016, 5, 65.
-
(2016)
J. Clin. Med
, vol.5
-
-
Felipe Lima, J.1
Nofech-Mozes, S.2
Bayani, J.3
Bartlett, J.M.4
-
9
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S.A., Guo, W., Liao, M., Eaton, E.N., Zhou, A.Y., Brooks, M., Reinhard, F., Zhang, C.C., Campbell, L.L., Polyak, K., et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133, 704–715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.3
Eaton, E.N.4
Zhou, A.Y.5
Brooks, M.6
Reinhard, F.7
Zhang, C.C.8
Campbell, L.L.9
Polyak, K.10
-
10
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel, A.P., Lièvre, M., Thomas, C., Hinkal, G., Ansieau, S., Puisieux, A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE 2008, 3, e2888.
-
(2008)
Plos ONE
, vol.3
-
-
Morel, A.P.1
Lièvre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
11
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj, M., Wicha, M.S., Benito-Hernandez, A., Morrison, S.J., Clarke, M.F. Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 2003, 100, 3983–3988.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
12
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S.J., Clarke, M.F., Weissman, I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414, 105–111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
13
-
-
56749095797
-
Transcriptional regulation of cell polarity in EMT and cancer
-
Moreno-Bueno, G., Portillo, F., Cano, A. Transcriptional regulation of cell polarity in EMT and cancer. Oncogene 2008, 27, 6958–6969.
-
(2008)
Oncogene
, vol.27
, pp. 6958-6969
-
-
Moreno-Bueno, G.1
Portillo, F.2
Cano, A.3
-
14
-
-
85022223430
-
Upholding a role for EMT in breast cancer metastasis
-
Ye, X., Brabletz, T., Kang, Y., Longmore, G.D., Nieto, M.A., Stanger, B.Z., Yang, J., Weinberg, R.A. Upholding a role for EMT in breast cancer metastasis. Nature 2017, 547, E1–E3.
-
(2017)
Nature
, vol.547
, pp. E1-E3
-
-
Ye, X.1
Brabletz, T.2
Kang, Y.3
Longmore, G.D.4
Nieto, M.A.5
Stanger, B.Z.6
Yang, J.7
Weinberg, R.A.8
-
15
-
-
85031034333
-
Fisher et al. Replay
-
Fisher, K.R., Altorki, N.K., Mittal, V., Gao, D. Fisher et al. replay. Nature 2017, 547, E5–E6.
-
(2017)
Nature
, vol.547
, pp. E5-E6
-
-
Fisher, K.R.1
Altorki, N.K.2
Mittal, V.3
Gao, D.4
-
16
-
-
33645289670
-
Biphasic metaplastic sarcomatoid carcinoma of the breast
-
Hennessy, B.T., Giordano, S., Broglio, K., Duan, Z., Trent, J., Buchholz, T.A., Babiera, G., Hortobagyi, G.N., Valero, V. Biphasic metaplastic sarcomatoid carcinoma of the breast. Ann. Oncol. 2006, 17, 605–613.
-
(2006)
Ann. Oncol
, vol.17
, pp. 605-613
-
-
Hennessy, B.T.1
Giordano, S.2
Broglio, K.3
Duan, Z.4
Trent, J.5
Buchholz, T.A.6
Babiera, G.7
Hortobagyi, G.N.8
Valero, V.9
-
17
-
-
66249109653
-
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
-
Hennessy, B.T., Gonzalez-Angulo, A.M., Stemke-Hale, K., Gilcrease, M.Z., Krishnamurthy, S., Lee, J.S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res. 2009, 69, 4116–4124.
-
(2009)
Cancer Res
, vol.69
, pp. 4116-4124
-
-
Hennessy, B.T.1
Gonzalez-Angulo, A.M.2
Stemke-Hale, K.3
Gilcrease, M.Z.4
Krishnamurthy, S.5
Lee, J.S.6
Fridlyand, J.7
Sahin, A.8
Agarwal, R.9
Joy, C.10
-
18
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R., Liang, J., Ni, S., Zhou, T., Qing, X., Li, H., He, W., Chen, J., Li, F., Zhuang, Q., et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010, 7, 51–63.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
Zhou, T.4
Qing, X.5
Li, H.6
He, W.7
Chen, J.8
Li, F.9
Zhuang, Q.10
-
19
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani, P., Golipour, A., David, L., Sung, H.K., Beyer, T.A., Datti, A., Woltjen, K., Nagy, A., Wrana, J.L. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 2010, 7, 64–77.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
Golipour, A.2
David, L.3
Sung, H.K.4
Beyer, T.A.5
Datti, A.6
Woltjen, K.7
Nagy, A.8
Wrana, J.L.9
-
20
-
-
84974799241
-
Mesenchymal to epithelial transition induced by reprogramming factors attenuates the malignancy of cancer cells
-
Takaishi, M., Tarutani, M., Takeda, J., Sano, S. Mesenchymal to epithelial transition induced by reprogramming factors attenuates the malignancy of cancer cells. PLoS ONE 2016, 11, e0156904.
-
(2016)
Plos ONE
, vol.11
-
-
Takaishi, M.1
Tarutani, M.2
Takeda, J.3
Sano, S.4
-
21
-
-
84055216938
-
Mechanism of the mesenchymal-epithelial transition and its relationship with metastatic tumor formation.
-
Yao, D., Dai, C., Peng, S. Mechanism of the mesenchymal-epithelial transition and its relationship with metastatic tumor formation. Mol. Cancer Res. 2011, 9, 1608–1620.
-
(2011)
Mol. Cancer Res
, vol.9
, pp. 1608-1620
-
-
Yao, D.1
Dai, C.2
Peng, S.3
-
22
-
-
70349213381
-
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling
-
Micalizzi, D.S., Christensen, K.L., Jedlicka, P., Coletta, R.D., Barón, A.E., Harrell, J.C., Horwitz, K.B., Billheimer, D., Heichman, K.A., Welm, A.L., et al. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. J. Clin. Investig. 2009, 119, 2678–2690.
-
(2009)
J. Clin. Investig
, vol.119
, pp. 2678-2690
-
-
Micalizzi, D.S.1
Christensen, K.L.2
Jedlicka, P.3
Coletta, R.D.4
Barón, A.E.5
Harrell, J.C.6
Horwitz, K.B.7
Billheimer, D.8
Heichman, K.A.9
Welm, A.L.10
-
23
-
-
84946893352
-
Emerging prognostic markers related to mesenchymal characteristics of poorly differentiated breast cancers
-
Scimeca, M., Antonacci, C., Colombo, D., Bonfiglio, R., Buonomo, O.C., Bonanno, E. Emerging prognostic markers related to mesenchymal characteristics of poorly differentiated breast cancers. Tumour Biol. 2016, 37, 5427–5435.
-
(2016)
Tumour Biol
, vol.37
, pp. 5427-5435
-
-
Scimeca, M.1
Antonacci, C.2
Colombo, D.3
Bonfiglio, R.4
Buonomo, O.C.5
Bonanno, E.6
-
24
-
-
47549090432
-
TGFβ in Cancer
-
Massagué, J. TGFβ in Cancer. Cell 2008, 134, 215–230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
25
-
-
0028603343
-
TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors.
-
Miettinen, P.J., Ebner, R., Lopez, A.R., Derynck, R. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors. J. Cell Biol. 1994, 127, 2021–2036.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 2021-2036
-
-
Miettinen, P.J.1
Ebner, R.2
Lopez, A.R.3
Derynck, R.4
-
26
-
-
0034574298
-
How cells read TGF-beta signals
-
Massagué, J. How cells read TGF-beta signals. Nat. Rev. Mol. Cell Biol. 2000, 1, 169–178.
-
(2000)
Nat. Rev. Mol. Cell Biol
, vol.1
, pp. 169-178
-
-
Massagué, J.1
-
27
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck, R., Zhang, Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003, 425, 577–584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
28
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
-
Ozdamar, B., Bose, R., Barrios-Rodiles, M., Wang, H.R., Zhang, Y., Wrana, J.L. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 2005, 307, 1603–1609.
-
(2005)
Science
, vol.307
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
29
-
-
0037459077
-
Sticky business: Orchestrating cellular signals at adherens junctions
-
Perez-Moreno, M., Jamora, C., Fuchs, E. Sticky business: Orchestrating cellular signals at adherens junctions. Cell 2003, 112, 535–548.
-
(2003)
Cell
, vol.112
, pp. 535-548
-
-
Perez-Moreno, M.1
Jamora, C.2
Fuchs, E.3
-
30
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil, J., Böttinger, E.P. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005, 24, 5764–5774.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Böttinger, E.P.2
-
31
-
-
0035185853
-
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol
-
Bhowmick, N.A., Ghiassi, M., Bakin, A., Aakre, M., Lundquist, C.A., Engel, M.E., Arteaga, C.L., Moses, H.L. Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol. Cell 2001, 12, 27–36.
-
(2001)
Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
Engel, M.E.6
Arteaga, C.L.7
Moses, H.L.8
-
32
-
-
0035805595
-
The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation
-
Shen, X., Li, J., Hu, P.P., Waddell, D., Zhang, J., Wang, X.F. The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation. J. Biol. Chem. 2001, 276, 15362–15368.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 15362-15368
-
-
Shen, X.1
Li, J.2
Hu, P.P.3
Waddell, D.4
Zhang, J.5
Wang, X.F.6
-
33
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley, A.J., Hall, A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992, 70, 389–399.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
34
-
-
0035651254
-
Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nat
-
Fukata, M., Kaibuchi, K. Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nat.Rev. Mol. Cell Biol. 2001, 2, 887–897.
-
(2001)
Rev. Mol. Cell Biol
, vol.2
, pp. 887-897
-
-
Fukata, M.1
Kaibuchi, K.2
-
35
-
-
0034666839
-
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
-
Lehmann, K., Janda, E., Pierreux, C.E., Rytömaa, M., Schulze, A., McMahon, M., Hill, C.S., Beug, H., Downward, J. Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells. Genes Dev. 2000, 14, 2610–2622.
-
(2000)
Genes Dev
, vol.14
, pp. 2610-2622
-
-
Lehmann, K.1
Janda, E.2
Pierreux, C.E.3
Rytömaa, M.4
Schulze, A.5
McMahon, M.6
Hill, C.S.7
Beug, H.8
Downward, J.9
-
36
-
-
0037148532
-
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
-
Janda, E., Lehmann, K., Killisch, I., Jechlinger, M., Herzig, M., Downward, J., Beug, H., Grünert, S. Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways. J. Cell Biol. 2002, 156, 299–313.
-
(2002)
J. Cell Biol
, vol.156
, pp. 299-313
-
-
Janda, E.1
Lehmann, K.2
Killisch, I.3
Jechlinger, M.4
Herzig, M.5
Downward, J.6
Beug, H.7
Grünert, S.8
-
37
-
-
1842524153
-
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
-
Zavadil, J., Cermak, L., Soto-Nieves, N., Böttinger, E.P. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition. EMBO J. 2004, 23, 1155–1165.
-
(2004)
EMBO J
, vol.23
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Böttinger, E.P.4
-
38
-
-
2342643464
-
Beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition
-
Eger, A., Stockinger, A., Park, J., Langkopf, E., Mikula, M., Gotzmann, J., Mikulits, W., Beug, H., Foisner, R. Beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene 2004, 23, 2672–2680.
-
(2004)
Oncogene
, vol.23
, pp. 2672-2680
-
-
Eger, A.1
Stockinger, A.2
Park, J.3
Langkopf, E.4
Mikula, M.5
Gotzmann, J.6
Mikulits, W.7
Beug, H.8
Foisner, R.9
-
39
-
-
84879826154
-
Wnt pathway activity in breast cancer sub-types and stem-like cells
-
Lamb, R., Ablett, M.P., Spence, K., Landberg, G., Sims, A.H., Clarke, R.B. Wnt pathway activity in breast cancer sub-types and stem-like cells. PLoS ONE 2013, 8, e67811.
-
(2013)
Plos ONE
, vol.8
-
-
Lamb, R.1
Ablett, M.P.2
Spence, K.3
Landberg, G.4
Sims, A.H.5
Clarke, R.B.6
-
40
-
-
33751514601
-
A Wnt-Axin2-3β cascade regulates Snail1 activity in breast cancer cells.
-
Yook, J.I., Li, X.Y., Ota, I., Hu, C., Kim, H.S., Kim, N.H., Cha, S.Y., Ryu, J.K., Choi, Y.J., Kim, J., et al. A Wnt-Axin2-3β cascade regulates Snail1 activity in breast cancer cells. Nat. Cell Biol. 2006, 8, 1398–1406.
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 1398-1406
-
-
Yook, J.I.1
Li, X.Y.2
Ota, I.3
Hu, C.4
Kim, H.S.5
Kim, N.H.6
Cha, S.Y.7
Ryu, J.K.8
Choi, Y.J.9
Kim, J.10
-
41
-
-
0345599013
-
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK
-
Conacci-Sorrell, M., Simcha, I., Ben-Yedidia, T., Blechman, J., Savagner, P., Ben-Ze’ev, A. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK. J. Cell Biol. 2003, 163, 847–857.
-
(2003)
J. Cell Biol
, vol.163
, pp. 847-857
-
-
Conacci-Sorrell, M.1
Simcha, I.2
Ben-Yedidia, T.3
Blechman, J.4
Savagner, P.5
Ben-Ze’ev, A.6
-
42
-
-
0345700653
-
Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation
-
Howe, L.R., Watanabe, O., Leonard, J., Brown, A.M. Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation. Cancer Res. 2003, 63, 1906–1913.
-
(2003)
Cancer Res
, vol.63
, pp. 1906-1913
-
-
Howe, L.R.1
Watanabe, O.2
Leonard, J.3
Brown, A.M.4
-
43
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127, 469–480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
44
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
Taelman, V.F., Dobrowolski, R., Plouhinec, J.L., Fuentealba, L.C., Vorwald, P.P., Gumper, I., Sabatini, D.D., De Robertis, E.M. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 2010, 143, 1136–1148.
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
Dobrowolski, R.2
Plouhinec, J.L.3
Fuentealba, L.C.4
Vorwald, P.P.5
Gumper, I.6
Sabatini, D.D.7
De Robertis, E.M.8
-
45
-
-
36849048683
-
Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function
-
Bhat, R.A., Stauffer, B., Komm, B.S., Bodine, P.V. Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function. J. Cell. Biochem. 2007, 102, 1519–1528.
-
(2007)
J. Cell. Biochem
, vol.102
, pp. 1519-1528
-
-
Bhat, R.A.1
Stauffer, B.2
Komm, B.S.3
Bodine, P.V.4
-
46
-
-
33845359084
-
Function and biological roles of the Dickkopf family of Wnt modulators
-
Niehrs, C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 2006, 25, 7469–7481.
-
(2006)
Oncogene
, vol.25
, pp. 7469-7481
-
-
Niehrs, C.1
-
47
-
-
40849116461
-
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
-
Suzuki, H., Toyota, M., Carraway, H., Gabrielson, E., Ohmura, T., Fujikane, T., Nishikawa, N., Sogabe, Y., Nojima, M., Sonoda, T., et al. Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br. J. Cancer 2008, 98, 1147–1156.
-
(2008)
Br. J. Cancer
, vol.98
, pp. 1147-1156
-
-
Suzuki, H.1
Toyota, M.2
Carraway, H.3
Gabrielson, E.4
Ohmura, T.5
Fujikane, T.6
Nishikawa, N.7
Sogabe, Y.8
Nojima, M.9
Sonoda, T.10
-
48
-
-
85016934868
-
Wnt signaling in triple-negative breast cancer
-
Pohl, S.G., Brook, N., Agostino, M., Arfuso, F., Kumar, A.P., Dharmarajan, A. Wnt signaling in triple-negative breast cancer. Oncogenesis 2017, 6, e310.
-
(2017)
Oncogenesis
, vol.6
-
-
Pohl, S.G.1
Brook, N.2
Agostino, M.3
Arfuso, F.4
Kumar, A.P.5
Dharmarajan, A.6
-
49
-
-
0037313260
-
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.
-
Ishitani, T., Ninomiya-Tsuji, J., Matsumoto, K. Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling. Mol. Cell. Biol. 2003, 23, 1379–1389.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 1379-1389
-
-
Ishitani, T.1
Ninomiya-Tsuji, J.2
Matsumoto, K.3
-
50
-
-
67650496215
-
A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer
-
DiMeo, T.A., Anderson, K., Phadke, P., Fan, C., Perou, C.M., Naber, S., Kuperwasser, C. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res. 2009, 69, 5364–5373.
-
(2009)
Cancer Res
, vol.69
, pp. 5364-5373
-
-
Dimeo, T.A.1
Erson, K.2
Phadke, P.3
Fan, C.4
Perou, C.M.5
Naber, S.6
Kuperwasser, C.7
-
51
-
-
84922523490
-
β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells
-
Xu, J., Prosperi, J.R., Choudhury, N., Olopade, O.I., Goss, K.H. β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells. PLoS ONE 2015, 10, e0117097.
-
(2015)
Plos ONE
, vol.10
-
-
Xu, J.1
Prosperi, J.R.2
Choudhury, N.3
Olopade, O.I.4
Goss, K.H.5
-
52
-
-
85016934062
-
Deregulation of the non-canonical pathway in triple-negative breast cancer
-
Borg, J.-P., Belotti, E., Daulat, A., Lembo, F., Bertucci, F., Charafe-Jauffret, E., Birnbaum, D. Deregulation of the non-canonical pathway in triple-negative breast cancer. FASEB J. 2013, 27.
-
(2013)
FASEB J.
-
-
Borg, J.-P.1
Belotti, E.2
Daulat, A.3
Lembo, F.4
Bertucci, F.5
Charafe-Jauffret, E.6
Birnbaum, D.7
-
53
-
-
33644752839
-
Notch signaling
-
Miele, L. Notch signaling. Clin. Cancer Res. 2006, 12, 1074–1079.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 1074-1079
-
-
Miele, L.1
-
54
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
Leong, K.G., Karsan, A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 2006, 107, 2223–2233.
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
55
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat
-
Weijzen, S., Rizzo, P., Braid, M., Vaishnav, R., Jonkheer, S.M., Zlobin, A., Osborne, B.A., Gottipati, S., Aster, J.C., Hahn, W.C., et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat. Med. 2002, 8, 979–986.
-
(2002)
Med
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
Osborne, B.A.7
Gottipati, S.8
Aster, J.C.9
Hahn, W.C.10
-
56
-
-
33644857012
-
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism
-
Ayyanan, A., Civenni, G., Ciarloni, L., Morel, C., Mueller, N., Lefort, K., Mandinova, A., Raffoul, W., Fiche, M., Dotto, G.P., Brisken, C. Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc. Natl. Acad. Sci. USA 2006, 103, 3799–3804.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3799-3804
-
-
Ayyanan, A.1
Civenni, G.2
Ciarloni, L.3
Morel, C.4
Mueller, N.5
Lefort, K.6
Mandinova, A.7
Raffoul, W.8
Fiche, M.9
Dotto, G.P.10
Brisken, C.11
-
57
-
-
78951481235
-
Role of Notch and its oncogenic signaling crosstalk in breast cancer.
-
Guo, S., Liu, M., Gonzalez-Perez, R.R. Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim. Biophys. Acta 2011, 1815, 197–213.
-
(2011)
Biochim. Biophys. Acta
, vol.1815
, pp. 197-213
-
-
Guo, S.1
Liu, M.2
Gonzalez-Perez, R.R.3
-
58
-
-
84917709274
-
Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: Novel therapeutic strategy for aggressive breast cancers.
-
Mittal, S., Sharma, A., Balaji, S.A., Gowda, M.C., Dighe, R.R., Kumar, R.V., Rangarajan, A. Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: Novel therapeutic strategy for aggressive breast cancers. Mol. Cancer Ther. 2014, 13, 3198–3209.
-
(2014)
Mol. Cancer Ther
, vol.13
, pp. 3198-3209
-
-
Mittal, S.1
Sharma, A.2
Balaji, S.A.3
Gowda, M.C.4
Dighe, R.R.5
Kumar, R.V.6
-
59
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
-
Leong, K.G., Niessen, K., Kulic, I., Raouf, A., Eaves, C., Pollet, I., Karsan, A. Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J. Exp. Med. 2007, 204, 2935–2948.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
Karsan, A.7
-
60
-
-
84899716244
-
Notch-1 signaling promotes the malignant features of human breast cancer through NF-αB activation
-
Li, L., Zhao, F., Lu, J., Li, T., Yang, H., Wu, C., Liu, Y. Notch-1 signaling promotes the malignant features of human breast cancer through NF-αB activation. PLoS ONE 2014, 9, e95912.
-
(2014)
Plos ONE
, vol.9
-
-
Li, L.1
Zhao, F.2
Lu, J.3
Li, T.4
Yang, H.5
Wu, C.6
Liu, Y.7
-
61
-
-
0029871104
-
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis
-
Gallahan, D., Jhappan, C., Robinson, G., Hennighausen, L., Sharp, R., Kordon, E., Callahan, R., Merlino, G., Smith, G.H. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 1996, 56, 1775–1785.
-
(1996)
Cancer Res
, vol.56
, pp. 1775-1785
-
-
Gallahan, D.1
Jhappan, C.2
Robinson, G.3
Hennighausen, L.4
Sharp, R.5
Kordon, E.6
Callahan, R.7
Merlino, G.8
Smith, G.H.9
-
62
-
-
33644660241
-
Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors
-
Hu, C., Diévart, A., Lupien, M., Calvo, E., Tremblay, G., Jolicoeur, P. Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors. Am. J. Pathol. 2006, 168, 973–990.
-
(2006)
Am. J. Pathol
, vol.168
, pp. 973-990
-
-
Hu, C.1
Diévart, A.2
Lupien, M.3
Calvo, E.4
Tremblay, G.5
Jolicoeur, P.6
-
63
-
-
77953700950
-
Targeting Notch to target cancer stem cells. Clin
-
Pannuti, A., Foreman, K., Rizzo, P., Osipo, C., Golde, T., Osborne, B., Miele, L. Targeting Notch to target cancer stem cells. Clin. Cancer Res. 2010, 16, 3141–3152.
-
(2010)
Cancer Res
, vol.16
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
Osborne, B.6
Miele, L.7
-
64
-
-
85020522602
-
Notch3 inhibits epithelial-mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells
-
Zhang, X., Liu, X., Luo, J., Xiao, W., Ye, X., Chen, M., Li, Y., Zhang, G.J. Notch3 inhibits epithelial-mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells. Oncogenesis 2016, 5, e269.
-
(2016)
Oncogenesis
, vol.5
-
-
Zhang, X.1
Liu, X.2
Luo, J.3
Xiao, W.4
Ye, X.5
Chen, M.6
Li, Y.7
Zhang, G.J.8
-
65
-
-
84875476208
-
The Hippo pathway and human cancer. Nat
-
Harvey, K.F., Zhang, X., Thomas, D.M. The Hippo pathway and human cancer. Nat. Rev. Cancer 2013, 13, 246–257.
-
(2013)
Rev. Cancer
, vol.13
, pp. 246-257
-
-
Harvey, K.F.1
Zhang, X.2
Thomas, D.M.3
-
66
-
-
84938850800
-
A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness
-
Pegoraro, S., Ros, G., Ciani, Y., Sgarra, R., Piazza, S., Manfioletti, G. A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness. Oncotarget 2015, 6, 19087–190101.
-
(2015)
Oncotarget
, vol.6
, pp. 19087-190101
-
-
Pegoraro, S.1
Ros, G.2
Ciani, Y.3
Sgarra, R.4
Piazza, S.5
Manfioletti, G.6
-
67
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi, M., Zanconato, F., Azzolin, L., Forcato, M., Rosato, A., Frasson, C., Inui, M., Montagner, M., Parenti, A.R., Poletti, A., et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 2011, 147, 759–772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
-
68
-
-
33747591465
-
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
-
Overholtzer, M., Zhang, J., Smolen, G.A., Muir, B., Li, W., Sgroi, D.C., Deng, C.X., Brugge, J.S., Haber, D.A. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc. Natl. Acad. Sci. USA 2006, 103, 12405–12410.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12405-12410
-
-
Overholtzer, M.1
Zhang, J.2
Smolen, G.A.3
Muir, B.4
Li, W.5
Sgroi, D.C.6
Deng, C.X.7
Brugge, J.S.8
Haber, D.A.9
-
69
-
-
84893721816
-
TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
-
Bartucci, M., Dattilo, R., Moriconi, C., Pagliuca, A., Mottolese, M., Federici, G., Benedetto, A.D., Todaro, M., Stassi, G., Sperati, F., et al. TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells. Oncogene 2015, 34, 681–690.
-
(2015)
Oncogene
, vol.34
, pp. 681-690
-
-
Bartucci, M.1
Dattilo, R.2
Moriconi, C.3
Pagliuca, A.4
Mottolese, M.5
Federici, G.6
Benedetto, A.D.7
Todaro, M.8
Stassi, G.9
Sperati, F.10
-
70
-
-
84870261155
-
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker.
-
Chen, D., Sun, Y., Wei, Y., Zhang, P., Rezaeian, A.H., Teruya-Feldstein, J., Gupta, S., Liang, H., Lin, H.K., Hung, M.C., et al. LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nat. Med. 2012, 18, 1511–1517.
-
(2012)
Nat. Med
, vol.18
, pp. 1511-1517
-
-
Chen, D.1
Sun, Y.2
Wei, Y.3
Zhang, P.4
Rezaeian, A.H.5
Teruya-Feldstein, J.6
Gupta, S.7
Liang, H.8
Lin, H.K.9
Hung, M.C.10
-
71
-
-
79961087833
-
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
-
Kim, N.G., Koh, E., Chen, X., Gumbiner, B.M. E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc. Natl. Acad. Sci. USA 2011, 108, 11930–11935.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11930-11935
-
-
Kim, N.G.1
Koh, E.2
Chen, X.3
Gumbiner, B.M.4
-
72
-
-
84964397417
-
Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway.
-
Wang, Y., Liu, J., Ying, X., Lin, P.C., Zhou, B.P. Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway. Sci. Rep. 2016, 6, 24606.
-
(2016)
Sci. Rep
, vol.6
-
-
Wang, Y.1
Liu, J.2
Ying, X.3
Lin, P.C.4
Zhou, B.P.5
-
73
-
-
84958555092
-
ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types.
-
Lehmann, W., Mossmann, D., Kleemann, J., Mock, K., Meisinger, C., Brummer, T., Herr, R., Brabletz, S., Stemmler, M.P., Brabletz, T. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat. Commun. 2016, 7, 10498.
-
(2016)
Nat. Commun
, vol.7
-
-
Lehmann, W.1
Mossmann, D.2
Kleemann, J.3
Mock, K.4
Meisinger, C.5
Brummer, T.6
Herr, R.7
Brabletz, S.8
Stemmler, M.P.9
Brabletz, T.10
-
74
-
-
84916910418
-
The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway
-
Salah, Z., Itzhaki, E., Aqeilan, R.I. The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway. Oncotarget 2014, 5, 10886–10900.
-
(2014)
Oncotarget
, vol.5
, pp. 10886-10900
-
-
Salah, Z.1
Itzhaki, E.2
Aqeilan, R.I.3
-
75
-
-
84992458887
-
The hedgehog pathway in triple-negative breast cancer
-
Habib, J.G., O’Shaughnessy, J.A. The hedgehog pathway in triple-negative breast cancer. Cancer Med. 2016, 5, 2989–3006.
-
(2016)
Cancer Med
, vol.5
, pp. 2989-3006
-
-
Habib, J.G.1
O’Shaughnessy, J.A.2
-
76
-
-
57049089995
-
Hedgehog Signaling in Development and Cancer.
-
Jiang, J., Hui, C.C. Hedgehog Signaling in Development and Cancer. Dev. Cell 2008, 15, 801–812.
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
77
-
-
0032848136
-
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
-
Sasaki, H., Nishizaki, Y., Hui, C., Nakafuku, M., Kondoh, H. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 1999, 126, 3915–3924.
-
(1999)
Development
, vol.126
, pp. 3915-3924
-
-
Sasaki, H.1
Nishizaki, Y.2
Hui, C.3
Nakafuku, M.4
-
78
-
-
84863252342
-
Noncanonical Hedgehog signaling.
-
Brennan, D., Chen, X., Cheng, L., Mahoney, M., Riobo, N.A. Noncanonical Hedgehog signaling. Vitam. Horm. 2012, 88, 55–72.
-
(2012)
Vitam. Horm
, vol.88
, pp. 55-72
-
-
Brennan, D.1
Chen, X.2
Cheng, L.3
Mahoney, M.4
Riobo, N.A.5
-
79
-
-
35848938488
-
Non-canonical activation of GLI transcription factors: Implications for targeted anti-cancer therapy.
-
Lauth, M., Toftgård, R. Non-canonical activation of GLI transcription factors: Implications for targeted anti-cancer therapy. Cell Cycle 2007, 6, 2458–2463.
-
(2007)
Cell Cycle
, vol.6
, pp. 2458-2463
-
-
Lauth, M.1
Toftgård, R.2
-
80
-
-
84908117043
-
Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFB) pathway
-
Colavito, S.A., Zou, M.R., Yan, Q., Nguyen, D.X., Stern, D.F. Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFB) pathway. Breast Cancer Res. 2014, 16, 444.
-
(2014)
Breast Cancer Res
, vol.16
-
-
Colavito, S.A.1
Zou, M.R.2
Yan, Q.3
Nguyen, D.X.4
Stern, D.F.5
-
81
-
-
84876895507
-
Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to Smoothened-targeting Hedgehog inhibition.
-
Das, S., Samant, R.S., Shevde, L.A. Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to Smoothened-targeting Hedgehog inhibition. J. Biol. Chem. 2013, 288, 11824–11833.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 11824-11833
-
-
Das, S.1
Samant, R.S.2
Shevde, L.A.3
-
82
-
-
84931025000
-
Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer
-
Lei, J., Fan, L., Wei, G., Chen, X., Duan, W., Xu, Q., Sheng, W., Wang, K., Li, X. Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer. Tumour Biol. 2015, 36, 3119–3126.
-
(2015)
Tumour Biol
, vol.36
, pp. 3119-3126
-
-
Lei, J.1
Fan, L.2
Wei, G.3
Chen, X.4
Duan, W.5
Xu, Q.6
Sheng, W.7
Wang, K.8
Li, X.9
-
83
-
-
66349097441
-
Development of mammary tumors by conditional expression of GLI1
-
Fiaschi, M., Rozell, B., Bergström, A., Toftgård, R. Development of mammary tumors by conditional expression of GLI1. Cancer Res. 2009, 69, 4810–4817.
-
(2009)
Cancer Res
, vol.69
, pp. 4810-4817
-
-
Fiaschi, M.1
Rozell, B.2
Bergström, A.3
Toftgård, R.4
-
84
-
-
84907501988
-
Signaling mechanisms of the epithelial-mesenchymal transition
-
Gonzalez, D.M., Medici, D. Signaling mechanisms of the epithelial-mesenchymal transition. Sci. Signal. 2014, 7, re8.
-
(2014)
Sci. Signal.
, vol.7
-
-
Gonzalez, D.M.1
Medici, D.2
-
85
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy. Nat
-
Gschwind, A., Fischer, O.M., Ullrich, A. The discovery of receptor tyrosine kinases: Targets for cancer therapy. Nat. Rev. Cancer 2004, 4, 361–370.
-
(2004)
Rev. Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
86
-
-
75749115996
-
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
-
Gjerdrum, C., Tiron, C., Høiby, T., Stefansson, I., Haugen, H., Sandal, T., Collett, K., Li, S., McCormack, E., Gjertsen, B.T., Micklem, D.R., Akslen, L.A., Glackin, C., Lorens, J.B. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proc. Natl. Acad. Sci. USA 2010, 107, 1124–1129.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1124-1129
-
-
Gjerdrum, C.1
Tiron, C.2
Høiby, T.3
Stefansson, I.4
Haugen, H.5
Sandal, T.6
Collett, K.7
Li, S.8
McCormack, E.9
Gjertsen, B.T.10
Micklem, D.R.11
Akslen, L.A.12
Glackin, C.13
Lorens, J.B.14
-
87
-
-
85014642977
-
Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.
-
Schoumacher, M., Burbridge, M. Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies. Curr. Oncol. Rep. 2017, 19, 19.
-
(2017)
Curr. Oncol. Rep.
, vol.19
-
-
Schoumacher, M.1
Burbridge, M.2
-
88
-
-
84915809785
-
Crosstalk of Oncogenic Signaling Pathways during Epithelial-Mesenchymal Transition.
-
Lindsey, S., Langhans, S.A. Crosstalk of Oncogenic Signaling Pathways during Epithelial-Mesenchymal Transition. Front. Oncol. 2014, 4, 358.
-
(2014)
Front. Oncol
, vol.4
-
-
Lindsey, S.1
Langhans, S.A.2
-
89
-
-
33745192635
-
Autocrine PDGFR signaling promotes mammary cancer metastasis
-
Jechlinger, M., Sommer, A., Moriggl, R., Seither, P., Kraut, N., Capodiecci, P., Donovan, M., Cordon-Cardo, C., Beug, H., Grünert, S. Autocrine PDGFR signaling promotes mammary cancer metastasis. J. Clin. Investig. 2006, 116, 1561–1570.
-
(2006)
J. Clin. Investig
, vol.116
, pp. 1561-1570
-
-
Jechlinger, M.1
Sommer, A.2
Moriggl, R.3
Seither, P.4
Kraut, N.5
Capodiecci, P.6
Donovan, M.7
Cordon-Cardo, C.8
Beug, H.9
Grünert, S.10
-
90
-
-
84928391898
-
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis
-
Wagenblast, E., Soto, M., Gutiérrez-Ángel, S., Hartl, C.A., Gable, A.L., Maceli, A.R., Erard, N., Williams, A.M., Kim, S.Y., Dickopf, S., et al. A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis. Nature 2015, 520, 358–362.
-
(2015)
Nature
, vol.520
, pp. 358-362
-
-
Wagenblast, E.1
Soto, M.2
Gutiérrez-Ángel, S.3
Hartl, C.A.4
Gable, A.L.5
Maceli, A.R.6
Erard, N.7
Williams, A.M.8
Kim, S.Y.9
Dickopf, S.10
-
91
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities. Nat
-
Desgrosellier, J.S., Cheresh, D.A. Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer 2010, 10, 9–22.
-
(2010)
Rev. Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
92
-
-
85030992723
-
Aptamer-mediated impairment of EGFR-integrin avβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.
-
Camorani, S., Crescenzi, E., Gramanzini, M., Fedele, M., Zannetti, A., Cerchia, L. Aptamer-mediated impairment of EGFR-integrin avβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers. Sci. Rep. 2017, 7, 46659.
-
(2017)
Sci. Rep
, vol.7
-
-
Camorani, S.1
Crescenzi, E.2
Gramanzini, M.3
Fedele, M.4
Zannetti, A.5
Cerchia, L.6
-
93
-
-
84988913063
-
MiR-9 and miR-200 regulate pdgfrβ-mediated endothelial differentiation of tumor cells in triple-negative breast cancer
-
D'Ippolito, E., Plantamura, I., Bongiovanni, L., Casalini, P., Baroni, S., Piovan, C., Orlandi, R., Gualeni, A.V., Gloghini, A., Rossini, A., et al. miR-9 and miR-200 regulate pdgfrβ-mediated endothelial differentiation of tumor cells in triple-negative breast cancer. Cancer Res. 2016, 76, 5562–5572.
-
(2016)
Cancer Res
, vol.76
, pp. 5562-5572
-
-
D'ippolito, E.1
Plantamura, I.2
Bongiovanni, L.3
Casalini, P.4
Baroni, S.5
Piovan, C.6
Orlandi, R.7
Gualeni, A.V.8
Gloghini, A.9
Rossini, A.10
-
94
-
-
84899860489
-
An integrin β3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
-
Seguin, L., Kato, S., Franovic, A., Camargo, M.F., Lesperance, J., Elliott, K.C., Yebra, M., Mielgo, A., Lowy, A.M., Husain, H., et al. An integrin β3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat. Cell Biol. 2014, 16, 457–468.
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 457-468
-
-
Seguin, L.1
Kato, S.2
Franovic, A.3
Camargo, M.F.4
Lesperance, J.5
Elliott, K.C.6
Yebra, M.7
Mielgo, A.8
Lowy, A.M.9
Husain, H.10
-
95
-
-
84924912028
-
Integrin traffic-The update
-
De Franceschi, N., Hamidi, H., Alanko, J., Sahgal, P., Ivaska, J. Integrin traffic-The update. J. Cell Sci. 2015, 128, 839–852.
-
(2015)
J. Cell Sci
, vol.128
, pp. 839-852
-
-
De Franceschi, N.1
Hamidi, H.2
Alanko, J.3
Sahgal, P.4
Ivaska, J.5
-
96
-
-
0034704174
-
Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain
-
Borges, E., Jan, Y., Ruoslahti, E. Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain. J. Biol. Chem. 2000, 275, 39867–39873.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 39867-39873
-
-
Borges, E.1
Jan, Y.2
Ruoslahti, E.3
-
97
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
Malanchi, I., Santamaria-Martínez, A., Susanto, E., Peng, H., Lehr, H.A., Delaloye, J.F., Huelsken, J. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 2012, 481, 85–89.
-
(2012)
Nature
, vol.481
, pp. 85-89
-
-
Malanchi, I.1
Santamaria-Martínez, A.2
Susanto, E.3
Peng, H.4
Lehr, H.A.5
Delaloye, J.F.6
Huelsken, J.7
-
98
-
-
77954861244
-
Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer
-
Radisky, E.S., Radisky, D.C. Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer. J. Mammary Gland Biol. Neoplasia 2010, 5, 201–212.
-
(2010)
J. Mammary Gland Biol. Neoplasia
, vol.5
, pp. 201-212
-
-
Radisky, E.S.1
Radisky, D.C.2
-
99
-
-
84884817862
-
The secretome in cancer progression. Biochim. Biophys
-
Paltridge, J.L., Belle, L., Khew-Goodall, Y. The secretome in cancer progression. Biochim. Biophys. Acta 2013, 1834, 2233–2241.
-
(2013)
Acta
, vol.1834
, pp. 2233-2241
-
-
Paltridge, J.L.1
Belle, L.2
Khew-Goodall, Y.3
-
100
-
-
77957755656
-
Secretome proteomics for discovery of cancer biomarkers
-
Makridakis, M., Vlahou, A. Secretome proteomics for discovery of cancer biomarkers. J. Proteom. 2010, 73, 2291–2305.
-
(2010)
J. Proteom
, vol.73
, pp. 2291-2305
-
-
Makridakis, M.1
Vlahou, A.2
-
101
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan, D., Coussens, L.M. Accessories to the crime: Functions of cells recruited to the tumor microenvironment. Cancer Cell 2012, 21, 309–322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
102
-
-
84893769522
-
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
-
Yu, Y., Xiao, C.H., Tan, L.D., Wang, Q.S., Li, X.Q., Feng, Y.M. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling. Br. J. Cancer 2014, 110, 724–732.
-
(2014)
Br. J. Cancer
, vol.110
, pp. 724-732
-
-
Yu, Y.1
Xiao, C.H.2
Tan, L.D.3
Wang, Q.S.4
Li, X.Q.5
Feng, Y.M.6
-
103
-
-
84879605585
-
Bone marrow cells as precursors of the tumor stroma. Exp
-
Worthley, D.L., Si, Y., Quante, M., Churchill, M., Mukherjee, S., Wang, T.C. Bone marrow cells as precursors of the tumor stroma. Exp. Cell Res. 2013, 319, 1650–1656.
-
(2013)
Cell Res
, vol.319
, pp. 1650-1656
-
-
Worthley, D.L.1
Si, Y.2
Quante, M.3
Churchill, M.4
Mukherjee, S.5
Wang, T.C.6
-
104
-
-
84887522014
-
Tumor microenvironment: Bone marrow-mesenchymal stem cells as key players.
-
Barcellos-de-Souza, P., Gori, V., Bambi, F., Chiarugi, P. Tumor microenvironment: Bone marrow-mesenchymal stem cells as key players. Biochim. Biophys. Acta 2013, 1836, 321–335.
-
(2013)
Biochim. Biophys. Acta
, vol.1836
, pp. 321-335
-
-
Barcellos-De-Souza, P.1
Gori, V.2
Bambi, F.3
Chiarugi, P.4
-
105
-
-
85028455983
-
Inhibition of bone marrow-derived mesenchymal stem cells homing towards triple-negative breast cancer microenvironment using an anti-PDGFRβ aptamer
-
Camorani, S., Hill, B.S., Fontanella, R., Greco, A., Gramanzini, M., Auletta, L., Gargiulo, S., Albanese, S., Lucarelli, E., Cerchia, L., et al. Inhibition of bone marrow-derived mesenchymal stem cells homing towards triple-negative breast cancer microenvironment using an anti-PDGFRβ aptamer. Theranostic 2017, 7, 3595–3607.
-
(2017)
Theranostic
, vol.7
, pp. 3595-3607
-
-
Camorani, S.1
Hill, B.S.2
Fontanella, R.3
Greco, A.4
Gramanzini, M.5
Auletta, L.6
Gargiulo, S.7
Albanese, S.8
Lucarelli, E.9
Cerchia, L.10
-
106
-
-
33847419142
-
Molecular definition of breast tumor heterogeneity
-
Shipitsin, M., Campbell, L.L., Argani, P., Weremowicz, S., Bloushtain-Qimron, N., Yao, J., Nikolskaya, T., Serebryiskaya, T., Beroukhim, R., Hu, M., et al. Molecular definition of breast tumor heterogeneity. Cancer Cell 2007, 11, 259–273.
-
(2007)
Cancer Cell
, vol.11
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
Weremowicz, S.4
Bloushtain-Qimron, N.5
Yao, J.6
Nikolskaya, T.7
Serebryiskaya, T.8
Beroukhim, R.9
Hu, M.10
-
107
-
-
85018217578
-
Cancer stem cells regulate cancer-associated fibroblasts via activation of hedgehog signaling in mammary gland tumors
-
Valenti, G., Quinn, H.M., Heynen, G.J.J.E., Lan, L., Holland, J.D., Vogel, R., Wulf-Goldenberg, A., Birchmeier, W. Cancer stem cells regulate cancer-associated fibroblasts via activation of hedgehog signaling in mammary gland tumors. Cancer Res 2017, 77, 2134–2147.
-
(2017)
Cancer Res
, vol.77
, pp. 2134-2147
-
-
Valenti, G.1
Quinn, H.M.2
Heynen, G.J.J.E.3
Lan, L.4
Holland, J.D.5
Vogel, R.6
Wulf-Goldenberg, A.7
Birchmeier, W.8
-
108
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
Wyckoff, J., Wang, W., Lin, E.Y., Wang, Y., Pixley, F., Stanley, E.R., Graf, T., Pollard, J.W., Segall, J., Condeelis, J. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res. 2004, 64, 7022–7029.
-
(2004)
Cancer Res
, vol.64
, pp. 7022-7029
-
-
Wyckoff, J.1
Wang, W.2
Lin, E.Y.3
Wang, Y.4
Pixley, F.5
Stanley, E.R.6
Graf, T.7
Pollard, J.W.8
Segall, J.9
Condeelis, J.10
-
109
-
-
84908485098
-
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.
-
Lu, H., Clauser, K.R., Tam, W.L., Fröse, J., Ye, X., Eaton, E.N., Reinhardt, F., Donnenberg, V.S., Bhargava, R., Carr, S.A., et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat. Cell Biol. 2014, 16, 1105–1117.
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 1105-1117
-
-
Lu, H.1
Clauser, K.R.2
Tam, W.L.3
Fröse, J.4
Ye, X.5
Eaton, E.N.6
Reinhardt, F.7
Donnenberg, V.S.8
Bhargava, R.9
Carr, S.A.10
-
110
-
-
81855169565
-
Cancer invasion and the microenvironment: Plasticity and reciprocity
-
Friedl, P., Alexander, S. Cancer invasion and the microenvironment: Plasticity and reciprocity. Cell 2011, 147, 992–1009.
-
(2011)
Cell
, vol.147
, pp. 992-1009
-
-
Friedl, P.1
Alexander, S.2
-
111
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel, C., Eaton, E.N., Li, S.H., Chaffer, C.L., Reinhardt, F., Kah, K.J., Bell, G., Guo, W., Rubin, J., Richardson, A.L., et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 2011, 145, 926–940.
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
Kah, K.J.6
Bell, G.7
Guo, W.8
Rubin, J.9
Richardson, A.L.10
-
112
-
-
84869069142
-
Cell surface remodeling by plasmin: A new function for an old enzyme
-
Deryugina, E.I., Quigley, J.P. Cell surface remodeling by plasmin: A new function for an old enzyme. J. Biomed. Biotechnol. 2012, 2012, 564259.
-
(2012)
J. Biomed. Biotechnol
, vol.2012
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
113
-
-
84910070390
-
UPA and PAI-1 as biomarkers in breast cancer: Validated for clinical use in level-of-evidence-1 studies
-
Duffy, M.J., McGowan, P.M., Harbeck, N., Thomssen, C., Schmitt, M. uPA and PAI-1 as biomarkers in breast cancer: Validated for clinical use in level-of-evidence-1 studies. Breast Cancer Res. 2014, 16, 428.
-
(2014)
Breast Cancer Res
, vol.16
-
-
Duffy, M.J.1
McGowan, P.M.2
Harbeck, N.3
Thomssen, C.4
Schmitt, M.5
-
114
-
-
0037102368
-
Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (UPA) and plasminogen activator inhibitor type 1 (n = 3424)
-
Harbeck, N., Kates, R.E., Look, M.P., Meijer-Van Gelder, M.E., Klijn, J.G., Krüger, A., Kiechle, M., Jänicke, F., Schmitt, M., Foekens, J.A. Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424). Cancer Res. 2002, 62, 4617–4622.
-
(2002)
Cancer Res
, vol.62
, pp. 4617-4622
-
-
Harbeck, N.1
Kates, R.E.2
Look, M.P.3
Meijer-Van Gelder, M.E.4
Klijn, J.G.5
Krüger, A.6
Kiechle, M.7
Jänicke, F.8
Schmitt, M.9
Foekens, J.A.10
-
115
-
-
67650073241
-
Breast Cancer Study Group of the Institut Curie. Urokinase-type plasminogen activator and plasminogen-activator-inhibitor type 1 predict metastases in good prognosis breast cancer patients
-
De Cremoux, P., Grandin, L., Diéras, V., Savignoni, A., Degeorges, A., Salmon, R., Bollet, M.A., Reyal, F., Sigal-Zafrani, B., Vincent-Salomon, A., et al. Breast Cancer Study Group of the Institut Curie. Urokinase-type plasminogen activator and plasminogen-activator-inhibitor type 1 predict metastases in good prognosis breast cancer patients. Anticancer Res. 2009, 29, 1475–1482.
-
(2009)
Anticancer Res
, vol.29
, pp. 1475-1482
-
-
De Cremoux, P.1
Grandin, L.2
Diéras, V.3
Savignoni, A.4
Degeorges, A.5
Salmon, R.6
Bollet, M.A.7
Reyal, F.8
Sigal-Zafrani, B.9
Vincent-Salomon, A.10
-
116
-
-
84875373539
-
The urokinase plasminogen activator system in breast cancer invasion and metastasis. Biomed
-
Tang, L., Han, X. The urokinase plasminogen activator system in breast cancer invasion and metastasis. Biomed. Pharmacother. 2012, 67, 179–182.
-
(2012)
Pharmacother
, vol.67
, pp. 179-182
-
-
Tang, L.1
Han, X.2
-
117
-
-
84915814932
-
The emerging role of exosomes in epithelial-mesenchymal-transition in cancer. Front
-
Vella, L.J. The emerging role of exosomes in epithelial-mesenchymal-transition in cancer. Front. Oncol. 2014, 4, 361.
-
(2014)
Oncol
, vol.4
-
-
Vella, L.J.1
-
118
-
-
67949097489
-
Exosomes-Vesicular carriers for intercellular communication
-
Simons, M., Raposo, G. Exosomes-Vesicular carriers for intercellular communication. Curr. Opin. Cell Biol. 2009, 21, 575–581.
-
(2009)
Curr. Opin. Cell Biol
, vol.21
, pp. 575-581
-
-
Simons, M.1
Raposo, G.2
-
119
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
Luga, V., Zhang, L., Viloria-Petit, A.M., Ogunjimi, A.A., Inanlou, M.R., Chiu, E., Buchanan, M., Hosein, A.N., Basik, M., Wrana, J.L. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 2012, 151, 1542–1556.
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
Zhang, L.2
Viloria-Petit, A.M.3
Ogunjimi, A.A.4
Inanlou, M.R.5
Chiu, E.6
Buchanan, M.7
Hosein, A.N.8
Basik, M.9
Wrana, J.L.10
-
120
-
-
84885420896
-
Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model. Mol. Cell
-
Lin, R., Wang, S., Zhao, R.C. Exosomes from human adipose-derived mesenchymal stem cells promote migration through Wnt signaling pathway in a breast cancer cell model. Mol. Cell. Biochem. 2013, 383, 13–20.
-
(2013)
Biochem
, vol.383
, pp. 13-20
-
-
Lin, R.1
Wang, S.2
Zhao, R.C.3
-
121
-
-
84890149349
-
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
-
Menck, K., Klemm, F., Gross, J.C., Pukrop, T., Wenzel, D., Binder, C. Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget 2013, 4, 2057–2066.
-
(2013)
Oncotarget
, vol.4
, pp. 2057-2066
-
-
Menck, K.1
Klemm, F.2
Gross, J.C.3
Pukrop, T.4
Wenzel, D.5
Binder, C.6
-
122
-
-
85017344838
-
Aberrant low expression of p85 in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b
-
Chen, Y., Zeng, C., Zhan, Y., Wang, H., Jiang, X., Li, W. Aberrant low expression of p85
-
(2017)
Oncogene
, vol.36
, pp. 4692-4705
-
-
Chen, Y.1
Zeng, C.2
Zhan, Y.3
Wang, H.4
Jiang, X.5
Li, W.6
-
123
-
-
84455171408
-
Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells
-
Cho, J.A., Park, H., Lim, E.H., Lee, K.W. Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells. Int. J. Oncol. 2012, 40, 130–138.
-
(2012)
Int. J. Oncol
, vol.40
, pp. 130-138
-
-
Cho, J.A.1
Park, H.2
Lim, E.H.3
Lee, K.W.4
-
124
-
-
84866502787
-
Hypoxic enhancement of exosome release by breast cancer cells
-
King, H.W., Michael, M.Z., Gleadle, J.M. Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer 2012, 12, 421.
-
(2012)
BMC Cancer
, vol.12
-
-
King, H.W.1
Michael, M.Z.2
Gleadle, J.M.3
-
125
-
-
47049119934
-
MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand ephrin-A3
-
Fasanaro, P., D’Alessandra, Y., Di Stefano, V., Melchionna, R., Romani, S., Pompilio, G., Capogrossi, M.C., Martelli, F. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand ephrin-A3. J. Biol. Chem. 2008, 283, 15878–15883.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 15878-15883
-
-
Fasanaro, P.1
D’Alessandra, Y.2
Di Stefano, V.3
Melchionna, R.4
Romani, S.5
Pompilio, G.6
Capogrossi, M.C.7
Martelli, F.8
-
126
-
-
84868000009
-
MicroRNA control of epithelial-mesenchymal transition and metastasis
-
Zhang, J., Ma, L. MicroRNA control of epithelial-mesenchymal transition and metastasis. Cancer Metastasis Rev. 2012, 31, 653–662.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 653-662
-
-
Zhang, J.1
Ma, L.2
-
127
-
-
34249302620
-
Lötvall, J.O. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat
-
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J.J., Lötvall, J.O. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 2007, 9, 654–659.
-
(2007)
Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekström, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.J.5
-
128
-
-
80053175966
-
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells.
-
Yang, M., Chen, J., Su, F., Yu, B., Su, F., Lin, L., Liu, Y., Huang, J.D., Song, E. Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol. Cancer 2011, 10, 117.
-
(2011)
Mol. Cancer
, vol.10
-
-
Yang, M.1
Chen, J.2
Su, F.3
Yu, B.4
Su, F.5
Lin, L.6
Liu, Y.7
Huang, J.D.8
Song, E.9
-
129
-
-
85015356299
-
MicroRNAs regulate the epithelial-mesenchymal transition and influence breast cancer invasion and metastasis
-
Zhao, M., Ang, L., Huang, J., Wang, J. MicroRNAs regulate the epithelial-mesenchymal transition and influence breast cancer invasion and metastasis. Tumour Biol. 2017, 39.
-
(2017)
Tumour Biol.
-
-
Zhao, M.1
Ang, L.2
Huang, J.3
Wang, J.4
-
130
-
-
77953898940
-
A microRNA targeting dicer for metastasis control
-
Martello, G., Rosato, A., Ferrari, F., Manfrin, A., Cordenonsi, M., Dupont, S., Enzo, E., Guzzardo, V., Rondina, M., Spruce, T., et al. A microRNA targeting dicer for metastasis control. Cell 2010, 141, 1195–1207.
-
(2010)
Cell
, vol.141
, pp. 1195-1207
-
-
Martello, G.1
Rosato, A.2
Ferrari, F.3
Manfrin, A.4
Cordenonsi, M.5
Dupont, S.6
Enzo, E.7
Guzzardo, V.8
Rondina, M.9
Spruce, T.10
-
131
-
-
84903710564
-
Family of pleiotropically acting microRNAs in cancer progression, miR-200: Potential cancer therapeutic targets
-
Zhang, H.F., Xu, L.Y., Li, E.M. A family of pleiotropically acting microRNAs in cancer progression, miR-200: Potential cancer therapeutic targets. Curr. Pharm. Des. 2014, 20, 1896–1903.
-
(2014)
Curr. Pharm. Des
, vol.20
, pp. 1896-1903
-
-
Zhang, H.F.1
Xu, L.Y.2
Li, E.3
-
132
-
-
84960441572
-
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
-
Pattabiraman, D.R., Bierie, B., Kober, K.I., Thiru, P., Krall, J.A., Zill, C., Reinhardt, F., Tam, W.L., Weinberg, R.A. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science 2016, 351, aad3680.
-
(2016)
Science
, vol.351
-
-
Pattabiraman, D.R.1
Bierie, B.2
Kober, K.I.3
Thiru, P.4
Krall, J.A.5
Zill, C.6
Reinhardt, F.7
Tam, W.L.8
Weinberg, R.A.9
-
133
-
-
85021034956
-
Targeting the epithelial-to-mesenchymal transition: The case for differentiation-based therapy.
-
Pattabiraman, D.R., Weinberg, R.A. Targeting the epithelial-to-mesenchymal transition: The case for differentiation-based therapy. Cold Spring Harb. Symp. Quant. Biol. 2016, 81, 11–19.
-
(2016)
Cold Spring Harb. Symp. Quant. Biol
, vol.81
, pp. 11-19
-
-
Pattabiraman, D.R.1
Weinberg, R.A.2
-
134
-
-
85031026447
-
Inducing a mesenchymal-to-epithelial transition for the differentiation therapy of aggressive breast carcinomas
-
Florence, Italy, 24–27 June
-
Pattabiraman, D., Ostendorp, J., Weinberg, R. Inducing a mesenchymal-to-epithelial transition for the differentiation therapy of aggressive breast carcinomas. In Proceedings of the EACR-AACR-SIC Special Conference 2017: The Challenges of Optimizing Immuno- and Targeted Therapies: From Cancer Biology to the Clinic, Florence, Italy, 24–27 June 2017.
-
(2017)
Proceedings of The EACR-AACR-SIC Special Conference 2017: The Challenges of Optimizing Immuno- and Targeted Therapies: From Cancer Biology to The Clinic
-
-
Pattabiraman, D.1
Ostendorp, J.2
Weinberg, R.3
-
135
-
-
84896489562
-
Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states
-
Yoshida, T., Ozawa, Y., Kimura, T., Sato, Y., Kuznetsov, G., Xu, S., Uesugi, M., Agoulnik, S., Taylor, N., Funahashi, Y., et al. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Br. J. Cancer 2014, 110, 1497–1505.
-
(2014)
Br. J. Cancer
, vol.110
, pp. 1497-1505
-
-
Yoshida, T.1
Ozawa, Y.2
Kimura, T.3
Sato, Y.4
Kuznetsov, G.5
Xu, S.6
Uesugi, M.7
Agoulnik, S.8
Taylor, N.9
Funahashi, Y.10
-
136
-
-
85011887080
-
Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression.
-
Lin, D., Kuang, G., Wan, J., Zhang, X., Li, H., Gong, X., Li, H. Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression. Oncol. Rep. 2017, 37, 1148–1158.
-
(2017)
Oncol. Rep
, vol.37
, pp. 1148-1158
-
-
Lin, D.1
Kuang, G.2
Wan, J.3
Zhang, X.4
Li, H.5
Gong, X.6
Li, H.7
-
137
-
-
84930177583
-
Diallyl disulfide inhibits growth and metastatic potential of human triple-negative breast cancer cells through inactivation of the β-catenin signaling pathway
-
Huang, J., Yang, B., Xiang, T., Peng, W., Qiu, Z., Wan, J., Zhang, L., Li, H., Li, H., Ren, G. Diallyl disulfide inhibits growth and metastatic potential of human triple-negative breast cancer cells through inactivation of the β-catenin signaling pathway. Mol. Nutr. Food Res. 2015, 9, 1063–1075.
-
(2015)
Mol. Nutr. Food Res
, vol.9
, pp. 1063-1075
-
-
Huang, J.1
Yang, B.2
Xiang, T.3
Peng, W.4
Qiu, Z.5
Wan, J.6
Zhang, L.7
Li, H.8
Li, H.9
Ren, G.10
-
138
-
-
84882763592
-
Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling pathway. Toxicol. Appl
-
Li, H., Huang, J., Yang, B., Xiang, T., Yin, X., Peng, W., Cheng, W., Wan, J., Luo, F., Li, H., et al. Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling pathway. Toxicol. Appl. Pharmacol. 2013, 272, 180–190.
-
(2013)
Pharmacol
, vol.272
, pp. 180-190
-
-
Li, H.1
Huang, J.2
Yang, B.3
Xiang, T.4
Yin, X.5
Peng, W.6
Cheng, W.7
Wan, J.8
Luo, F.9
Li, H.10
-
139
-
-
85020283295
-
Targeting epithelial-mesenchymal transition: Metal organic network nano-complexes for preventing tumor metastasis
-
Fan, J.X., Zheng, D.W., Rong, L., Zhu, J.Y., Hong, S., Li, C., Xu, Z.S., Cheng, S.X., Zhang, X.Z. Targeting epithelial-mesenchymal transition: Metal organic network nano-complexes for preventing tumor metastasis. Biomaterials 2017, 139, 116–126.
-
(2017)
Biomaterials
, vol.139
, pp. 116-126
-
-
Fan, J.X.1
Zheng, D.W.2
Rong, L.3
Zhu, J.Y.4
Hong, S.5
Li, C.6
Xu, Z.S.7
Cheng, S.X.8
Zhang, X.Z.9
-
140
-
-
85024107156
-
The ABC7 regimen: A new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy
-
Kast, R.E., Skuli, N., Cos, S., Karpel-Massler, G., Shiozawa, Y., Goshen, R., Halatsch, M.E. The ABC7 regimen: A new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy. Breast Cancer 2017, 9, 495–514.
-
(2017)
Breast Cancer
, vol.9
, pp. 495-514
-
-
Kast, R.E.1
Skuli, N.2
Cos, S.3
Karpel-Massler, G.4
Shiozawa, Y.5
Goshen, R.6
Halatsch, M.E.7
-
141
-
-
84904908675
-
Therapeutic targeting of integrin avβ6 in breast cancer
-
Moore, K.M., Thomas, G.J., Duffy, S.W., Warwick, J., Gabe, R., Chou, P., Ellis, I.O., Green, A.R., Haider, S., Brouilette, K., et al. Therapeutic targeting of integrin avβ6 in breast cancer. J. Natl. Cancer Inst. 2014, 106, dju169.
-
(2014)
J. Natl. Cancer Inst.
, vol.106
-
-
Moore, K.M.1
Thomas, G.J.2
Duffy, S.W.3
Warwick, J.4
Gabe, R.5
Chou, P.6
Ellis, I.O.7
Green, A.R.8
Haider, S.9
Brouilette, K.10
-
142
-
-
84934307591
-
Gene Knockdown by EpCAM Aptamer-siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells
-
Gilboa-Geffen, A., Hamar, P., Le, M.T., Wheeler, L.A., Trifonova, R., Petrocca, F., Wittrup, A., Lieberman, J. Gene Knockdown by EpCAM Aptamer-siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells. Mol. Cancer Ther. 2015, 14, 2279–2291.
-
(2015)
Mol. Cancer Ther
, vol.14
, pp. 2279-2291
-
-
Gilboa-Geffen, A.1
Hamar, P.2
Le, M.T.3
Wheeler, L.A.4
Trifonova, R.5
Petrocca, F.6
Wittrup, A.7
Lieberman, J.8
-
143
-
-
85021926133
-
Exosomal microRNAs in breast cancer towards diagnostic and therapeutic applications
-
Sempere, L.F., Keto, J., Fabbri, M. Exosomal microRNAs in breast cancer towards diagnostic and therapeutic applications. Cancers 2017, 9, 71.
-
(2017)
Cancers
, vol.9
-
-
Sempere, L.F.1
Keto, J.2
Fabbri, M.3
-
144
-
-
85029364427
-
MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling
-
Ma, F., Li, W., Liu, C., Li, W., Yu, H., Lei, B., Ren, Y., Li, Z., Pang, D., Qian, C. MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling. Oncotarget 2017, 8, 69538–69550.
-
(2017)
Oncotarget
, vol.8
, pp. 69538-69550
-
-
Ma, F.1
Li, W.2
Liu, C.3
Li, W.4
Yu, H.5
Lei, B.6
Ren, Y.7
Li, Z.8
Pang, D.9
Qian, C.10
-
145
-
-
85013243571
-
MiR520c blocks EMT progression of human breast cancer cells by repressing STAT3.
-
Wang, N., Wei, L., Huang, Y., Wu, Y., Su, M., Pang, X., Wang, N., Ji, F., Zhong, C., Chen, T., et al. miR520c blocks EMT progression of human breast cancer cells by repressing STAT3. Oncol. Rep. 2017, 37, 1537–1544.
-
(2017)
Oncol. Rep
, vol.37
, pp. 1537-1544
-
-
Wang, N.1
Wei, L.2
Huang, Y.3
Wu, Y.4
Su, M.5
Pang, X.6
Wang, N.7
Ji, F.8
Zhong, C.9
Chen, T.10
-
146
-
-
77950665077
-
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model.
-
Ma, L., Reinhard, F., Pan, E., Soutschek, J., Bhat, B., Marcusson, E.G., Teruya-Feldstein, J., Bell, G.W., Weinberg, R.A. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat. Biotechnol. 2010, 28, 341–347.
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 341-347
-
-
Ma, L.1
Reinhard, F.2
Pan, E.3
Soutschek, J.4
Bhat, B.5
Marcusson, E.G.6
Teruya-Feldstein, J.7
Bell, G.W.8
Weinberg, R.A.9
-
147
-
-
84949320826
-
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential
-
Knezevic, J., Pfefferle, A.D., Petrovic, I., Greene, S.B., Perou, C.M., Rosen, J.M. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene 2015, 34, 5997–6006.
-
(2015)
Oncogene
, vol.34
, pp. 5997-6006
-
-
Knezevic, J.1
Pfefferle, A.D.2
Petrovic, I.3
Greene, S.B.4
Perou, C.M.5
Rosen, J.M.6
-
148
-
-
84904065393
-
MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer
-
Bai, W.D., Ye, X.M., Zhang, M.Y., Zhu, H.Y., Xi, W.J., Huang, X., Zhao, J., Gu, B., Zheng, G.X., Yang, A.G., et al. MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer. Int. J. Cancer 2014, 135, 1356–1368.
-
(2014)
Int. J. Cancer
, vol.135
, pp. 1356-1368
-
-
Bai, W.D.1
Ye, X.M.2
Zhang, M.Y.3
Zhu, H.Y.4
Xi, W.J.5
Huang, X.6
Zhao, J.7
Gu, B.8
Zheng, G.X.9
Yang, A.G.10
-
149
-
-
84946079857
-
MiR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity
-
O’Brien, K., Lowry, M.C., Corcoran, C., Martinez, V.G., Daly, M., Rani, S., Gallagher, W.M., Radomski, M.W., MacLeod, R.A., O’Driscoll, L. miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity. Oncotarget 2015, 6, 32774–32789.
-
(2015)
Oncotarget
, vol.6
, pp. 32774-32789
-
-
O’Brien, K.1
Lowry, M.C.2
Corcoran, C.3
Martinez, V.G.4
Daly, M.5
Rani, S.6
Gallagher, W.M.7
Radomski, M.W.8
Macleod, R.A.9
O’Driscoll, L.10
-
150
-
-
84989234953
-
Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA).
-
Hannafon, B.N., Carpenter, K.J., Berry, W.L., Janknecht, R., Dooley, W.C., Ding, W.Q. Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA). Mol. Cancer 2015, 14, 133.
-
(2015)
Mol. Cancer
, vol.14
-
-
Hannafon, B.N.1
Carpenter, K.J.2
Berry, W.L.3
Janknecht, R.4
Dooley, W.C.5
Ding, W.Q.6
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