Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states

British Journal of Cancer

Volumn 110, Issue 6, 2014, Pages 1497-1505

  Yoshida, T ^a   Ozawa, Y ^a   Kimura, T ^a   Sato, Y ^a   Kuznetsov, G ^b   Xu, S ^b   Uesugi, M ^a   Agoulnik, S ^b   Taylor, N ^b   Funahashi, Y ^b   Matsui, J ^a  

^a EISAI CO LTD   (Japan)

^b EISAI INC   (United States)

Author keywords

EMT MET; eribulin mesilate; metastasis; triple negative breast cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERIBULIN; ESTROGEN RECEPTOR; FLUOROURACIL; NERVE CELL ADHESION MOLECULE; PROGESTERONE RECEPTOR; SMAD PROTEIN; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL TRANSFORMATION; CELL VIABILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MESENCHYMAL EPITHELIAL TRANSITION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; TUMOR INVASION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE-FREE SURVIVAL; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FURANS; GENE EXPRESSION; HUMANS; KETONES; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM METASTASIS; PHENOTYPE; TRIPLE NEGATIVE BREAST NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896489562     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.80     Document Type: Article

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