Cancer stem cells regulate cancer-associated fibroblasts via activation of hedgehog signaling in mammary gland tumors

Cancer Research

Volumn 77, Issue 8, 2017, Pages 2134-2147

  Valenti, Giovanni ^a   Quinn, Hazel M ^a   Heynen, Guus J J E ^a   Lan, Linxiang ^a   Holland, Jane D ^a   Vogel, Regina ^a   Wulf Goldenberg, Annika ^b   Birchmeier, Walter ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b Experimental Pharmacology and Oncology EPO GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; VISMODEGIB; ANILIDE; BETA CATENIN; CTNNB1 PROTEIN, MOUSE; PYRIDINE DERIVATIVE; SCATTER FACTOR RECEPTOR; WNT PROTEIN;

AGAR GEL ELECTROPHORESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; BRIGHT FIELD MICROSCOPY; CARCINOGENESIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING; MICROARRAY ANALYSIS; MOUSE; MTT ASSAY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THERAPY RESISTANCE; TUMOR GROWTH; WESTERN BLOTTING; ANIMAL; CANCER ASSOCIATED FIBROBLAST; CANCER STEM CELL; CELL COMMUNICATION; EXPERIMENTAL MAMMARY NEOPLASM; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY;

ANILIDES; ANIMALS; BETA CATENIN; CANCER-ASSOCIATED FIBROBLASTS; CELL COMMUNICATION; FEMALE; HEDGEHOG PROTEINS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-MET; PYRIDINES; SIGNAL TRANSDUCTION; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 85018217578     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-3490     Document Type: Article

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