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Volumn 32, Issue 9, 2017, Pages 1264-1310

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(38)  Obeso, J A a,b,c   Stamelou, M d,e   Goetz, C G f   Poewe, W g   Lang, A E h,i   Weintraub, D j,k   Burn, D l   Halliday, G M m,n   Bezard, E o,p   Przedborski, S q   Lehericy, S r,s   Brooks, D J l,t   Rothwell, J C u   Hallett, M v   DeLong, M R w   Marras, C x   Tanner, C M k,y   Ross, G W k   Langston, J W z   Klein, C aa   more..


Author keywords

200 years anniversary; Parkinson's disease; Shaking Palsy

Indexed keywords

ALPHA SYNUCLEIN; BIOLOGICAL MARKER; LEUCINE RICH REPEAT KINASE 2; LEVODOPA; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; VACUOLAR PROTEIN SORTING 35 HOMOLOG;

EID: 85028967067     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.27115     Document Type: Review
Times cited : (588)

References (299)
  • 5
    • 2942580548 scopus 로고
    • Some account of the effects of lightning
    • Parkinson J. Some account of the effects of lightning. Mem M Soc Lon 1789;2:490-500.
    • (1789) Mem M Soc Lon , vol.2 , pp. 490-500
    • Parkinson, J.1
  • 7
    • 70349211133 scopus 로고
    • On the treatment of infectious or typhoid fever
    • Parkinson J, Parkinson J. On the treatment of infectious or typhoid fever. Lond Med Repository 1824;1:197.
    • (1824) Lond Med Repository , vol.1 , pp. 197
    • Parkinson, J.1    Parkinson, J.2
  • 9
    • 0004277738 scopus 로고
    • London, Whittingham and Rowland Sherwood, Neely and Jones
    • Parkinson J. An Essay on the Shaking Palsy. London: Whittingham and Rowland Sherwood, Neely and Jones 1817.
    • (1817) An Essay on the Shaking Palsy
    • Parkinson, J.1
  • 10
    • 0025279441 scopus 로고
    • An essay on the shaking palsy: reviews and notes on the journals in which they appeared
    • Herzberg L. An essay on the shaking palsy: reviews and notes on the journals in which they appeared. Mov Disord 1990;5(2):162-166.
    • (1990) Mov Disord , vol.5 , Issue.2 , pp. 162-166
    • Herzberg, L.1
  • 12
    • 0030693154 scopus 로고    scopus 로고
    • The shaking palsy, the first forty-five years: a journey through the British literature
    • Louis ED. The shaking palsy, the first forty-five years: a journey through the British literature. Mov Disord 1997;12(6):1068-1072.
    • (1997) Mov Disord , vol.12 , Issue.6 , pp. 1068-1072
    • Louis, E.D.1
  • 13
    • 0001925175 scopus 로고
    • Charcot, the clinician: the Tuesday lessons: excerpts from nine case presentations on general neurology delivered at the Salpêtrière Hospital in 1887-88 by Jean-Martin Charcot
    • Fahn S, Goetz CG. Charcot, the clinician: the Tuesday lessons: excerpts from nine case presentations on general neurology delivered at the Salpêtrière Hospital in 1887-88 by Jean-Martin Charcot. Mov Disord 1987;4(1):123-140.
    • (1987) Mov Disord , vol.4 , Issue.1 , pp. 123-140
    • Fahn, S.1    Goetz, C.G.2
  • 15
    • 0024474825 scopus 로고
    • Did parkinsonism occur before 1817?
    • Stern G. Did parkinsonism occur before 1817? J Neurol Neurosurg Psychiatry 1989;52(suppl.):11-12.
    • (1989) J Neurol Neurosurg Psychiatry , vol.52 , pp. 11-12
    • Stern, G.1
  • 16
    • 0023898945 scopus 로고
    • The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • Gibb WR, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 1988;51(6):745-752.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , Issue.6 , pp. 745-752
    • Gibb, W.R.1    Lees, A.J.2
  • 17
    • 84944452191 scopus 로고    scopus 로고
    • MDS clinical diagnostic criteria for Parkinson's disease
    • Postuma RB, Berg D, Stern M, et al. MDS clinical diagnostic criteria for Parkinson's disease. Mov Disord 2015;30(12):1591-1601.
    • (2015) Mov Disord , vol.30 , Issue.12 , pp. 1591-1601
    • Postuma, R.B.1    Berg, D.2    Stern, M.3
  • 18
    • 0029267365 scopus 로고
    • An essay on Wilhelm von Humboldt and the shaking palsy: first comprehensive description of Parkinson's disease by a patient
    • Horowski R, Horowski L, Phil C, Vogel S, Poewe W, Kielhorn FW. An essay on Wilhelm von Humboldt and the shaking palsy: first comprehensive description of Parkinson's disease by a patient. Neurology 1995;45(3):565-568.
    • (1995) Neurology , vol.45 , Issue.3 , pp. 565-568
    • Horowski, R.1    Horowski, L.2    Phil, C.3    Vogel, S.4    Poewe, W.5    Kielhorn, F.W.6
  • 19
    • 84922268526 scopus 로고    scopus 로고
    • The onset of nonmotor symptoms in Parkinson's disease (the ONSET PDStudy)
    • Pont-Sunyer C, Hotter A, Gaig C, et al. The onset of nonmotor symptoms in Parkinson's disease (the ONSET PDStudy). Mov Disord 2015;30(2):229-237.
    • (2015) Mov Disord , vol.30 , Issue.2 , pp. 229-237
    • Pont-Sunyer, C.1    Hotter, A.2    Gaig, C.3
  • 20
    • 0014082977 scopus 로고
    • Parkinsonism: onset, progression, and mortality
    • Hoehn MM, Yahr MD. Parkinsonism: onset, progression, and mortality. Neurology 1967;17(5):427-427.
    • (1967) Neurology , vol.17 , Issue.5 , pp. 427
    • Hoehn, M.M.1    Yahr, M.D.2
  • 22
    • 0039859361 scopus 로고
    • Shift to older age distribution in parkinsonism: a report on 1,000 patients covering the past decade from three centers
    • Schwab RS, Doshay LJ, Garland H, Bradshaw P, Garvey E, Crawford B. Shift to older age distribution in parkinsonism: a report on 1,000 patients covering the past decade from three centers. Neurology 1956;6(11):783-790.
    • (1956) Neurology , vol.6 , Issue.11 , pp. 783-790
    • Schwab, R.S.1    Doshay, L.J.2    Garland, H.3    Bradshaw, P.4    Garvey, E.5    Crawford, B.6
  • 23
    • 2542612292 scopus 로고    scopus 로고
    • Time to move beyond nigrostriatal dopamine deficiency in Parkinson's disease
    • Lang AE, Obeso JA. Time to move beyond nigrostriatal dopamine deficiency in Parkinson's disease. Ann Neurol 2004;55(6):761-765.
    • (2004) Ann Neurol , vol.55 , Issue.6 , pp. 761-765
    • Lang, A.E.1    Obeso, J.A.2
  • 24
    • 79955112282 scopus 로고    scopus 로고
    • A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials
    • Lang AE. A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials. Mov Disord 2011;26(5):775-783.
    • (2011) Mov Disord , vol.26 , Issue.5 , pp. 775-783
    • Lang, A.E.1
  • 25
    • 34547764857 scopus 로고    scopus 로고
    • Patterns of levodopa response in Parkinson's disease: a clinico-pathological study
    • Kempster PA, Williams DR, Selikhova M, Holton J, Revesz T, Lees AJ. Patterns of levodopa response in Parkinson's disease: a clinico-pathological study. Brain 2007;130(8):2123-2128.
    • (2007) Brain , vol.130 , Issue.8 , pp. 2123-2128
    • Kempster, P.A.1    Williams, D.R.2    Selikhova, M.3    Holton, J.4    Revesz, T.5    Lees, A.J.6
  • 26
    • 84977590156 scopus 로고    scopus 로고
    • Motor subtype in Parkinson's disease: different disorders or different stages of disease?
    • Nutt JG. Motor subtype in Parkinson's disease: different disorders or different stages of disease? Mov Disord 2016;31(7):957-961.
    • (2016) Mov Disord , vol.31 , Issue.7 , pp. 957-961
    • Nutt, J.G.1
  • 27
    • 84981276418 scopus 로고    scopus 로고
    • Nonmotor features of Parkinson's disease subtypes
    • Marras C, Chaudhuri KR. Nonmotor features of Parkinson's disease subtypes. Mov Disord 2016;31(8):1095-1102.
    • (2016) Mov Disord , vol.31 , Issue.8 , pp. 1095-1102
    • Marras, C.1    Chaudhuri, K.R.2
  • 28
    • 84880966904 scopus 로고    scopus 로고
    • The heterogeneity of early Parkinson's disease: a cluster analysis on newly diagnosed untreated patients
    • Erro R, Vitale C, Amboni M, et al. The heterogeneity of early Parkinson's disease: a cluster analysis on newly diagnosed untreated patients. PLoS ONE 2013;8(8):e70244.
    • (2013) PLoS ONE , vol.8 , Issue.8
    • Erro, R.1    Vitale, C.2    Amboni, M.3
  • 30
    • 84929623987 scopus 로고    scopus 로고
    • Genetic risk and age in Parkinson's disease: continuum not stratum
    • Nalls MA, Escott-Price V, Williams NM, et al. Genetic risk and age in Parkinson's disease: continuum not stratum. Mov Disord 2015;30(6):850-854.
    • (2015) Mov Disord , vol.30 , Issue.6 , pp. 850-854
    • Nalls, M.A.1    Escott-Price, V.2    Williams, N.M.3
  • 31
    • 84965123533 scopus 로고    scopus 로고
    • α-synuclein genetic variability: a biomarker for dementia in Parkinson disease
    • Guella I, Evans DM, Szu-Tu C, et al. α-synuclein genetic variability: a biomarker for dementia in Parkinson disease. Ann Neurol 2016;79(6):991-999.
    • (2016) Ann Neurol , vol.79 , Issue.6 , pp. 991-999
    • Guella, I.1    Evans, D.M.2    Szu-Tu, C.3
  • 32
    • 85009962474 scopus 로고    scopus 로고
    • Precision medicine for disease modification in Parkinson disease
    • Espay AJ, Brundin P, Lang AE. Precision medicine for disease modification in Parkinson disease. Nat Rev Neurol 2017;13(2):119-126.
    • (2017) Nat Rev Neurol , vol.13 , Issue.2 , pp. 119-126
    • Espay, A.J.1    Brundin, P.2    Lang, A.E.3
  • 33
    • 84957837117 scopus 로고    scopus 로고
    • Accuracy of clinical diagnosis of Parkinson disease: a systematic review and meta-analysis
    • Rizzo G, Copetti M, Arcuti S, Martino D, Fontana A, Logroscino G. Accuracy of clinical diagnosis of Parkinson disease: a systematic review and meta-analysis. Neurology 2016;86(6):566-576.
    • (2016) Neurology , vol.86 , Issue.6 , pp. 566-576
    • Rizzo, G.1    Copetti, M.2    Arcuti, S.3    Martino, D.4    Fontana, A.5    Logroscino, G.6
  • 34
    • 84989323124 scopus 로고    scopus 로고
    • Arguing against the proposed definition changes of PD
    • Boeve BF, Dickson DW, Duda JE, et al. Arguing against the proposed definition changes of PD. Mov Disord 2016;31(11):1619-1622.
    • (2016) Mov Disord , vol.31 , Issue.11 , pp. 1619-1622
    • Boeve, B.F.1    Dickson, D.W.2    Duda, J.E.3
  • 35
    • 85014767759 scopus 로고    scopus 로고
    • Abolishing the 1-year rule: how much evidence will be enough?
    • Postuma RB, Berg D, Stern M, et al. Abolishing the 1-year rule: how much evidence will be enough? Mov Disord 2016;31(11):1623-1627.
    • (2016) Mov Disord , vol.31 , Issue.11 , pp. 1623-1627
    • Postuma, R.B.1    Berg, D.2    Stern, M.3
  • 36
    • 84918518903 scopus 로고    scopus 로고
    • Patients with scans without evidence of dopaminergic deficit: a long-term follow-up study
    • Batla A, Erro R, Stamelou M, et al. Patients with scans without evidence of dopaminergic deficit: a long-term follow-up study. Mov Disord 2014;29(14):1820-1825.
    • (2014) Mov Disord , vol.29 , Issue.14 , pp. 1820-1825
    • Batla, A.1    Erro, R.2    Stamelou, M.3
  • 37
    • 84952333587 scopus 로고    scopus 로고
    • A scan without evidence is not evidence of absence: scans without evidence of dopaminergic deficit in a symptomatic leucine-rich repeat kinase 2 mutation carrier
    • Wile DJ, Dinelle K, Vafai N, et al. A scan without evidence is not evidence of absence: scans without evidence of dopaminergic deficit in a symptomatic leucine-rich repeat kinase 2 mutation carrier. Mov Disord 2016;31(3):405-409.
    • (2016) Mov Disord , vol.31 , Issue.3 , pp. 405-409
    • Wile, D.J.1    Dinelle, K.2    Vafai, N.3
  • 38
    • 84873639356 scopus 로고    scopus 로고
    • Criteria for the diagnosis of corticobasal degeneration
    • Armstrong MJ, Litvan I, Lang AE, et al. Criteria for the diagnosis of corticobasal degeneration. Neurology 2013;80(5):496-503.
    • (2013) Neurology , vol.80 , Issue.5 , pp. 496-503
    • Armstrong, M.J.1    Litvan, I.2    Lang, A.E.3
  • 39
    • 52449086856 scopus 로고    scopus 로고
    • Second consensus statement on the diagnosis of multiple system atrophy
    • Gilman S, Wenning GK, Low PA, et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008;71(9):670-676.
    • (2008) Neurology , vol.71 , Issue.9 , pp. 670-676
    • Gilman, S.1    Wenning, G.K.2    Low, P.A.3
  • 40
    • 8944226575 scopus 로고    scopus 로고
    • Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP International Workshop
    • Litvan I, Agid Y, Calne D, et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP International Workshop. Neurology 1996;47(1):1-9.
    • (1996) Neurology , vol.47 , Issue.1 , pp. 1-9
    • Litvan, I.1    Agid, Y.2    Calne, D.3
  • 41
    • 84918581460 scopus 로고    scopus 로고
    • The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases
    • Respondek G, Stamelou M, Kurz C, et al. The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases. Mov Disord 2014;29(14):1758-1766.
    • (2014) Mov Disord , vol.29 , Issue.14 , pp. 1758-1766
    • Respondek, G.1    Stamelou, M.2    Kurz, C.3
  • 42
    • 84930038155 scopus 로고    scopus 로고
    • MRI signs of multiple system atrophy preceding the clinical diagnosis: the case for an imaging-supported probable MSA diagnostic category
    • Mestre TA, Gupta A, Lang AE. MRI signs of multiple system atrophy preceding the clinical diagnosis: the case for an imaging-supported probable MSA diagnostic category. J Neurol Neurosurg Psychiatry 2016;87(4):443-444.
    • (2016) J Neurol Neurosurg Psychiatry , vol.87 , Issue.4 , pp. 443-444
    • Mestre, T.A.1    Gupta, A.2    Lang, A.E.3
  • 43
    • 84905253917 scopus 로고    scopus 로고
    • Differentiating drug-induced parkinsonism from Parkinson's disease: an update on non-motor symptoms and investigations
    • Brigo F, Erro R, Marangi A, Bhatia K, Tinazzi M. Differentiating drug-induced parkinsonism from Parkinson's disease: an update on non-motor symptoms and investigations. Parkinsonism Relat Disord 2014;20(8):808-814.
    • (2014) Parkinsonism Relat Disord , vol.20 , Issue.8 , pp. 808-814
    • Brigo, F.1    Erro, R.2    Marangi, A.3    Bhatia, K.4    Tinazzi, M.5
  • 44
    • 84931957542 scopus 로고    scopus 로고
    • Vascular parkinsonism: deconstructing a syndrome
    • Vizcarra JA, Lang AE, Sethi KD, Espay AJ. Vascular parkinsonism: deconstructing a syndrome. Mov Disord 2015;30(7):886-894.
    • (2015) Mov Disord , vol.30 , Issue.7 , pp. 886-894
    • Vizcarra, J.A.1    Lang, A.E.2    Sethi, K.D.3    Espay, A.J.4
  • 45
    • 84876467498 scopus 로고    scopus 로고
    • Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series
    • Magdalinou NK, Ling H, Smith JDS, Schott JM, Watkins LD, Lees AJ. Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series. J Neurol 2013;260(4):1009-1013.
    • (2013) J Neurol , vol.260 , Issue.4 , pp. 1009-1013
    • Magdalinou, N.K.1    Ling, H.2    Smith, J.D.S.3    Schott, J.M.4    Watkins, L.D.5    Lees, A.J.6
  • 46
    • 84902275072 scopus 로고    scopus 로고
    • A practical approach to diagnosing adult onset leukodystrophies
    • Ahmed RM, Murphy E, Davagnanam I, et al. A practical approach to diagnosing adult onset leukodystrophies. J Neurol Neurosurg Psychiatry 2014;85(7):770-881.
    • (2014) J Neurol Neurosurg Psychiatry , vol.85 , Issue.7 , pp. 770-881
    • Ahmed, R.M.1    Murphy, E.2    Davagnanam, I.3
  • 47
    • 79957590886 scopus 로고    scopus 로고
    • Parkinson's disease: the quintessential neuropsychiatric disorder
    • Weintraub D, Burn DJ. Parkinson's disease: the quintessential neuropsychiatric disorder. Mov Disord 2011;26(6):1022-1031.
    • (2011) Mov Disord , vol.26 , Issue.6 , pp. 1022-1031
    • Weintraub, D.1    Burn, D.J.2
  • 48
    • 84873660450 scopus 로고    scopus 로고
    • The spectrum of nonmotor symptoms in early Parkinson disease: the ICICLE-PD study
    • Khoo TK, Yarnall AJ, Duncan GW, et al. The spectrum of nonmotor symptoms in early Parkinson disease: the ICICLE-PD study. Neurology 2013;80(3):276-281.
    • (2013) Neurology , vol.80 , Issue.3 , pp. 276-281
    • Khoo, T.K.1    Yarnall, A.J.2    Duncan, G.W.3
  • 49
    • 85020485882 scopus 로고    scopus 로고
    • Mild cognitive impairment as a risk factor for Parkinson's disease dementia
    • [published online ahead of print
    • Hoogland J, Boel JA, de Bie RMA. Mild cognitive impairment as a risk factor for Parkinson's disease dementia [published online ahead of print 2017]. Mov Disord.
    • (2017) Mov Disord
    • Hoogland, J.1    Boel, J.A.2    de Bie, R.M.A.3
  • 50
    • 84944460691 scopus 로고    scopus 로고
    • MDS research criteria for prodromal Parkinson's disease
    • Berg D, Postuma RB, Adler CH, et al. MDS research criteria for prodromal Parkinson's disease. Mov Disord 2015;30(12):1600-1611.
    • (2015) Mov Disord , vol.30 , Issue.12 , pp. 1600-1611
    • Berg, D.1    Postuma, R.B.2    Adler, C.H.3
  • 52
    • 84858298114 scopus 로고    scopus 로고
    • Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines
    • Litvan I, Goldman JG, Tröster AI, et al. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Mov Disord 2012;27(3):349-356.
    • (2012) Mov Disord , vol.27 , Issue.3 , pp. 349-356
    • Litvan, I.1    Goldman, J.G.2    Tröster, A.I.3
  • 53
    • 10044283107 scopus 로고    scopus 로고
    • Rivastigmine for dementia associated with Parkinson's disease
    • Emre M, Aarsland D, Albanese A, et al. Rivastigmine for dementia associated with Parkinson's disease. N Engl J Med 2004;351(24):2509-2518.
    • (2004) N Engl J Med , vol.351 , Issue.24 , pp. 2509-2518
    • Emre, M.1    Aarsland, D.2    Albanese, A.3
  • 54
    • 64049105010 scopus 로고    scopus 로고
    • A controlled trial of antidepressants in patients with Parkinson disease and depression
    • Menza M, Dobkin RD, Marin H, et al. A controlled trial of antidepressants in patients with Parkinson disease and depression. Neurology 2008;72(10):886-892.
    • (2008) Neurology , vol.72 , Issue.10 , pp. 886-892
    • Menza, M.1    Dobkin, R.D.2    Marin, H.3
  • 55
    • 84860785589 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson's disease
    • Richard I, McDermott M, Kurlan R, et al. A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson's disease. Neurology 2012;78:1229-1236.
    • (2012) Neurology , vol.78 , pp. 1229-1236
    • Richard, I.1    McDermott, M.2    Kurlan, R.3
  • 56
    • 80053243226 scopus 로고    scopus 로고
    • Cognitive-behavioral therapy for depression in Parkinson's disease: a randomized, controlled trial
    • Dobkin RD, Menza M, Allen LA, et al. Cognitive-behavioral therapy for depression in Parkinson's disease: a randomized, controlled trial. Am J Psychiatry 2011;168(10):1066-1074.
    • (2011) Am J Psychiatry , vol.168 , Issue.10 , pp. 1066-1074
    • Dobkin, R.D.1    Menza, M.2    Allen, L.A.3
  • 57
    • 77951833322 scopus 로고    scopus 로고
    • The changing face of Parkinson's disease-associated psychosis: a cross-sectional study based on the new NINDS-NIMH criteria
    • Fénelon G, Soulas T, Zenasni F, de Langavant LC. The changing face of Parkinson's disease-associated psychosis: a cross-sectional study based on the new NINDS-NIMH criteria. Mov Disord 2010;25(6):763-766.
    • (2010) Mov Disord , vol.25 , Issue.6 , pp. 763-766
    • Fénelon, G.1    Soulas, T.2    Zenasni, F.3    de Langavant, L.C.4
  • 58
    • 84956716318 scopus 로고    scopus 로고
    • Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase
    • Pagonabarraga J, Martinez-Horta S, Fernández de Bobadilla R, et al. Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase. Mov Disord 2016;31:45-52.
    • (2016) Mov Disord , vol.31 , pp. 45-52
    • Pagonabarraga, J.1    Martinez-Horta, S.2    Fernández de Bobadilla, R.3
  • 59
    • 84895904524 scopus 로고    scopus 로고
    • Pimavanserin for patients with Parkinson's disease psychosis: a randomised, placebo-controlled phase 3 trial
    • Cummings J, Isaacson S, Mills R, et al. Pimavanserin for patients with Parkinson's disease psychosis: a randomised, placebo-controlled phase 3 trial. Lancet 2014;383:533-540.
    • (2014) Lancet , vol.383 , pp. 533-540
    • Cummings, J.1    Isaacson, S.2    Mills, R.3
  • 60
    • 77952157407 scopus 로고    scopus 로고
    • Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients
    • Weintraub D, Koester J, Potenza M, et al. Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol 2010;67:589-595.
    • (2010) Arch Neurol , vol.67 , pp. 589-595
    • Weintraub, D.1    Koester, J.2    Potenza, M.3
  • 61
    • 85010383391 scopus 로고    scopus 로고
    • Current applications and limitations of surgical treatments for movement disorders
    • Krack P, Martinez-Fernandez R, del Alamo M, Obeso JA. Current applications and limitations of surgical treatments for movement disorders. Mov Disord 2017;32(1):36-52.
    • (2017) Mov Disord , vol.32 , Issue.1 , pp. 36-52
    • Krack, P.1    Martinez-Fernandez, R.2    del Alamo, M.3    Obeso, J.A.4
  • 62
    • 74949088519 scopus 로고    scopus 로고
    • Dopamine agonist withdrawal syndrome in Parkinson Disease
    • Rabinak CA, Nirenberg MJ. Dopamine agonist withdrawal syndrome in Parkinson Disease. Arch Neurol 2010;67(1):58-63.
    • (2010) Arch Neurol , vol.67 , Issue.1 , pp. 58-63
    • Rabinak, C.A.1    Nirenberg, M.J.2
  • 63
    • 77950687692 scopus 로고    scopus 로고
    • Substantia nigra and Parkinson's disease: a brief history of their long and intimate relationship
    • Parent M, Parent A. Substantia nigra and Parkinson's disease: a brief history of their long and intimate relationship. Can J Neurol Sci 2010;37(03):313-319.
    • (2010) Can J Neurol Sci , vol.37 , Issue.3 , pp. 313-319
    • Parent, M.1    Parent, A.2
  • 64
    • 84920870609 scopus 로고    scopus 로고
    • The medical treatment of Parkinson disease from James Parkinson to George Cotzias
    • Fahn S. The medical treatment of Parkinson disease from James Parkinson to George Cotzias. Mov Disord 2014;30(1):4-18.
    • (2014) Mov Disord , vol.30 , Issue.1 , pp. 4-18
    • Fahn, S.1
  • 65
    • 84906706633 scopus 로고    scopus 로고
    • Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease
    • Hall H, Reyes S, Landeck N, et al. Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease. Brain 2014;137(9):2493-2508.
    • (2014) Brain , vol.137 , Issue.9 , pp. 2493-2508
    • Hall, H.1    Reyes, S.2    Landeck, N.3
  • 66
    • 71849092190 scopus 로고    scopus 로고
    • Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
    • Dickson DW, Braak H, Duda JE, et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 2009;8(12):1150-1157.
    • (2009) Lancet Neurol , vol.8 , Issue.12 , pp. 1150-1157
    • Dickson, D.W.1    Braak, H.2    Duda, J.E.3
  • 67
    • 84946923292 scopus 로고    scopus 로고
    • Parkinson disease and incidental Lewy body disease: just a question of time?
    • Iacono D, Geraci-Erck M, Rabin ML, et al. Parkinson disease and incidental Lewy body disease: just a question of time? Neurology 2015;85(19):1670-1679.
    • (2015) Neurology , vol.85 , Issue.19 , pp. 1670-1679
    • Iacono, D.1    Geraci-Erck, M.2    Rabin, M.L.3
  • 68
    • 84968764106 scopus 로고    scopus 로고
    • Understanding dopaminergic cell death pathways in Parkinson disease
    • Michel PP, Hirsch EC, Hunot S. Understanding dopaminergic cell death pathways in Parkinson disease. Neuron 2016;90(4):675-691.
    • (2016) Neuron , vol.90 , Issue.4 , pp. 675-691
    • Michel, P.P.1    Hirsch, E.C.2    Hunot, S.3
  • 70
    • 84941598760 scopus 로고    scopus 로고
    • Disease-modifying strategies for Parkinson's disease
    • Kalia LV, Kalia SK, Lang AE. Disease-modifying strategies for Parkinson's disease. Mov Disord 2015;30(11):1442-1450.
    • (2015) Mov Disord , vol.30 , Issue.11 , pp. 1442-1450
    • Kalia, L.V.1    Kalia, S.K.2    Lang, A.E.3
  • 72
    • 79960842310 scopus 로고    scopus 로고
    • Neuropathology underlying clinical variability in patients with synucleinopathies
    • Halliday GM, Holton JL, Revesz T, Dickson DW. Neuropathology underlying clinical variability in patients with synucleinopathies. Acta Neuropathol 2011;122(2):187-204.
    • (2011) Acta Neuropathol , vol.122 , Issue.2 , pp. 187-204
    • Halliday, G.M.1    Holton, J.L.2    Revesz, T.3    Dickson, D.W.4
  • 73
    • 0024210648 scopus 로고
    • Lewy body disease with and without dementia: a clinicopathological study of 35 cases
    • Kosaka K, Tsuchiya K, Yoshimura M. Lewy body disease with and without dementia: a clinicopathological study of 35 cases. Clin Neuropathol 1988;7(6):299-305.
    • (1988) Clin Neuropathol , vol.7 , Issue.6 , pp. 299-305
    • Kosaka, K.1    Tsuchiya, K.2    Yoshimura, M.3
  • 75
    • 84950154375 scopus 로고    scopus 로고
    • Neuropathology of α-synuclein propagation and braak hypothesis
    • McCann H, Cartwright H, Halliday GM. Neuropathology of α-synuclein propagation and braak hypothesis. Mov Disord 2015;31(2):152-160.
    • (2015) Mov Disord , vol.31 , Issue.2 , pp. 152-160
    • McCann, H.1    Cartwright, H.2    Halliday, G.M.3
  • 76
    • 0000428532 scopus 로고
    • 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists
    • Carlsson A, Lindqvist M, Magnusson TOR. 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists. Nature 1957;180(4596):1200.
    • (1957) Nature , vol.180 , Issue.4596 , pp. 1200
    • Carlsson, A.1    Lindqvist, M.2    Magnusson, T.O.R.3
  • 77
    • 0014376793 scopus 로고
    • 6-hydroxy-dopamine induced degeneration of central monoamine neurons
    • Ungerstedt U. 6-hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 1968;5(1):107-110.
    • (1968) Eur J Pharmacol , vol.5 , Issue.1 , pp. 107-110
    • Ungerstedt, U.1
  • 78
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston J, Ballard P, Tetrud J, Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983;219(4587):979-980.
    • (1983) Science , vol.219 , Issue.4587 , pp. 979-980
    • Langston, J.1    Ballard, P.2    Tetrud, J.3    Irwin, I.4
  • 79
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the a-synuclein gene identified in families with Parkinson's disease
    • Polymeropoulos MH. Mutation in the a-synuclein gene identified in families with Parkinson's disease. Science 1997;276(5321):2045-2047.
    • (1997) Science , vol.276 , Issue.5321 , pp. 2045-2047
    • Polymeropoulos, M.H.1
  • 80
    • 0034704752 scopus 로고    scopus 로고
    • A drosophila model of Parkinson's disease
    • Feany MB, Bender WW. A drosophila model of Parkinson's disease. Nature 2000;404(6776):394-398.
    • (2000) Nature , vol.404 , Issue.6776 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 81
    • 0034681471 scopus 로고    scopus 로고
    • Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders
    • Masliah E. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 2000;287(5456):1265-1269.
    • (2000) Science , vol.287 , Issue.5456 , pp. 1265-1269
    • Masliah, E.1
  • 82
    • 33846636481 scopus 로고    scopus 로고
    • Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
    • Ekstrand MI, Terzioglu M, Galter D, et al. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proc Natl Acad Sci U S A 2007;104(4):1325-1330.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.4 , pp. 1325-1330
    • Ekstrand, M.I.1    Terzioglu, M.2    Galter, D.3
  • 83
    • 84869109864 scopus 로고    scopus 로고
    • Pathological alpha-synuclein transmission initiates parkinson-like neurodegeneration in nontransgenic mice
    • Luk KC, Kehm V, Carroll J, et al. Pathological alpha-synuclein transmission initiates parkinson-like neurodegeneration in nontransgenic mice. Science 2012;338(6109):949-953.
    • (2012) Science , vol.338 , Issue.6109 , pp. 949-953
    • Luk, K.C.1    Kehm, V.2    Carroll, J.3
  • 84
    • 84897977607 scopus 로고    scopus 로고
    • Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
    • Recasens A, Dehay B, Bové J, et al. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol 2014;75(3):351-362.
    • (2014) Ann Neurol , vol.75 , Issue.3 , pp. 351-362
    • Recasens, A.1    Dehay, B.2    Bové, J.3
  • 85
    • 79959305691 scopus 로고    scopus 로고
    • Mitochondria: the next (neurode) generation
    • Schon EA, Przedborski S. Mitochondria: the next (neurode) generation. Neuron 2011;70(6):1033-1053.
    • (2011) Neuron , vol.70 , Issue.6 , pp. 1033-1053
    • Schon, E.A.1    Przedborski, S.2
  • 86
    • 84994853544 scopus 로고    scopus 로고
    • α-synuclein-based animal models of Parkinson's disease: challenges and opportunities in a new era
    • Visanji NP, Brotchie JM, Kalia LV, et al. α-synuclein-based animal models of Parkinson's disease: challenges and opportunities in a new era. Trends Neurosci 2016;39(11):750-762.
    • (2016) Trends Neurosci , vol.39 , Issue.11 , pp. 750-762
    • Visanji, N.P.1    Brotchie, J.M.2    Kalia, L.V.3
  • 87
    • 84941599000 scopus 로고    scopus 로고
    • Basic science breaks through: New therapeutic advances in Parkinson's disease
    • Brundin P, Atkin G, Lamberts JT. Basic science breaks through: New therapeutic advances in Parkinson's disease. Mov Disord 2015;30(11):1521-1527.
    • (2015) Mov Disord , vol.30 , Issue.11 , pp. 1521-1527
    • Brundin, P.1    Atkin, G.2    Lamberts, J.T.3
  • 88
    • 42049123661 scopus 로고    scopus 로고
    • Midbrain iron content in early Parkinson disease: A potential biomarker of disease status
    • Martin WRW, Wieler M, Gee M. Midbrain iron content in early Parkinson disease: A potential biomarker of disease status. Neurology 2008;70(Pt 2):1411-1417.
    • (2008) Neurology , vol.70 , pp. 1411-1417
    • Martin, W.R.W.1    Wieler, M.2    Gee, M.3
  • 89
    • 84887296893 scopus 로고    scopus 로고
    • Diffusion tensor imaging of nigral degeneration in Parkinson's disease: a region-of-interest and voxel-based study at 3T and systematic review with meta-analysis
    • Schwarz ST, Abaei M, Gontu V, Morgan PS, Bajaj N, Auer DP. Diffusion tensor imaging of nigral degeneration in Parkinson's disease: a region-of-interest and voxel-based study at 3T and systematic review with meta-analysis. NeuroImage Clin 2013;3:481-488.
    • (2013) NeuroImage Clin , vol.3 , pp. 481-488
    • Schwarz, S.T.1    Abaei, M.2    Gontu, V.3    Morgan, P.S.4    Bajaj, N.5    Auer, D.P.6
  • 90
    • 84940093907 scopus 로고    scopus 로고
    • Longitudinal changes in free-water within the substantia nigra of Parkinson's disease
    • Ofori E, Pasternak O, Planetta PJ, et al. Longitudinal changes in free-water within the substantia nigra of Parkinson's disease. Brain 2015;138(8):2322-2331.
    • (2015) Brain , vol.138 , Issue.8 , pp. 2322-2331
    • Ofori, E.1    Pasternak, O.2    Planetta, P.J.3
  • 91
    • 84876135069 scopus 로고    scopus 로고
    • Parkinson's disease patients show reduced cortical-subcortical sensorimotor connectivity
    • Sharman M, Valabregue R, Perlbarg V, et al. Parkinson's disease patients show reduced cortical-subcortical sensorimotor connectivity. Mov Disord 2012;28(4):447-454.
    • (2012) Mov Disord , vol.28 , Issue.4 , pp. 447-454
    • Sharman, M.1    Valabregue, R.2    Perlbarg, V.3
  • 92
    • 84863229895 scopus 로고    scopus 로고
    • Seven-tesla magnetic resonance images of the substantia nigra in Parkinson disease
    • Kwon D-H, Kim J-M, Oh S-H, et al. Seven-tesla magnetic resonance images of the substantia nigra in Parkinson disease. Ann Neurol 2012;71(2):267-277.
    • (2012) Ann Neurol , vol.71 , Issue.2 , pp. 267-277
    • Kwon, D.-H.1    Kim, J.-M.2    Oh, S.-H.3
  • 93
    • 84931955307 scopus 로고    scopus 로고
    • Automated neuromelanin imaging as a diagnostic biomarker for Parkinson's disease
    • Castellanos G, Fernández-Seara MA, Lorenzo-Betancor O, et al. Automated neuromelanin imaging as a diagnostic biomarker for Parkinson's disease. Mov Disord 2015;30(7):945-952.
    • (2015) Mov Disord , vol.30 , Issue.7 , pp. 945-952
    • Castellanos, G.1    Fernández-Seara, M.A.2    Lorenzo-Betancor, O.3
  • 94
    • 78049460797 scopus 로고    scopus 로고
    • Magnetic resonance imaging markers of Parkinson's disease nigrostriatal signature
    • Peran P, Cherubini A, Assogna F, et al. Magnetic resonance imaging markers of Parkinson's disease nigrostriatal signature. Brain 2010;133(11):3423-3433.
    • (2010) Brain , vol.133 , Issue.11 , pp. 3423-3433
    • Peran, P.1    Cherubini, A.2    Assogna, F.3
  • 95
    • 84871754989 scopus 로고    scopus 로고
    • Resting state functional connectivity of the striatum in Parkinson's disease
    • Hacker CD, Perlmutter JS, Criswell SR, Ances BM, Snyder AZ. Resting state functional connectivity of the striatum in Parkinson's disease. Brain 2012;135(12):3699-3711.
    • (2012) Brain , vol.135 , Issue.12 , pp. 3699-3711
    • Hacker, C.D.1    Perlmutter, J.S.2    Criswell, S.R.3    Ances, B.M.4    Snyder, A.Z.5
  • 96
    • 84874847956 scopus 로고    scopus 로고
    • Rhythm-specific modulation of the sensorimotor network in drug-naïve patients with Parkinson's disease by levodopa
    • Esposito F, Tessitore A, Giordano A, et al. Rhythm-specific modulation of the sensorimotor network in drug-naïve patients with Parkinson's disease by levodopa. Brain 2013;136(3):710-725.
    • (2013) Brain , vol.136 , Issue.3 , pp. 710-725
    • Esposito, F.1    Tessitore, A.2    Giordano, A.3
  • 97
    • 84905817991 scopus 로고    scopus 로고
    • Functional connectivity in the basal ganglia network differentiates PD patients from controls
    • Szewczyk-Krolikowski K, Menke RAL, Rolinski M, et al. Functional connectivity in the basal ganglia network differentiates PD patients from controls. Neurology 2014;83(3):208-214.
    • (2014) Neurology , vol.83 , Issue.3 , pp. 208-214
    • Szewczyk-Krolikowski, K.1    Menke, R.A.L.2    Rolinski, M.3
  • 98
    • 84880965342 scopus 로고    scopus 로고
    • Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait
    • Fling BW, Cohen RG, Mancini M, Nutt JG, Fair DA, Horak FB. Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait. Brain 2013;136(8):2405-2418.
    • (2013) Brain , vol.136 , Issue.8 , pp. 2405-2418
    • Fling, B.W.1    Cohen, R.G.2    Mancini, M.3    Nutt, J.G.4    Fair, D.A.5    Horak, F.B.6
  • 99
    • 79952500499 scopus 로고    scopus 로고
    • Pallidal dysfunction drives a cerebellothalamic circuit into Parkinson tremor
    • Helmich RC, Janssen MJR, Oyen WJG, Bloem BR, Toni I. Pallidal dysfunction drives a cerebellothalamic circuit into Parkinson tremor. Ann Neurol 2011;69(2):269-281.
    • (2011) Ann Neurol , vol.69 , Issue.2 , pp. 269-281
    • Helmich, R.C.1    Janssen, M.J.R.2    Oyen, W.J.G.3    Bloem, B.R.4    Toni, I.5
  • 100
    • 84957940195 scopus 로고    scopus 로고
    • Consensus paper: towards a systems-level view of cerebellar function: the interplay between cerebellum, basal ganglia, and cortex
    • Caligiore D, Pezzulo G, Baldassarre G, et al. Consensus paper: towards a systems-level view of cerebellar function: the interplay between cerebellum, basal ganglia, and cortex. Cerebellum 2016;16(1):203-229.
    • (2016) Cerebellum , vol.16 , Issue.1 , pp. 203-229
    • Caligiore, D.1    Pezzulo, G.2    Baldassarre, G.3
  • 101
    • 84879932345 scopus 로고    scopus 로고
    • The coeruleus/subcoeruleus complex in rapid eye movement sleep behaviour disorders in Parkinson's disease
    • Garcia-Lorenzo D, Longo-Dos Santos C, Ewenczyk C, et al. The coeruleus/subcoeruleus complex in rapid eye movement sleep behaviour disorders in Parkinson's disease. Brain 2013;136(7):2120-2129.
    • (2013) Brain , vol.136 , Issue.7 , pp. 2120-2129
    • Garcia-Lorenzo, D.1    Longo-Dos Santos, C.2    Ewenczyk, C.3
  • 102
    • 84952681455 scopus 로고    scopus 로고
    • Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study
    • Mak E, Su L, Williams GB, et al. Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain 2015;138(10):2974-2986.
    • (2015) Brain , vol.138 , Issue.10 , pp. 2974-2986
    • Mak, E.1    Su, L.2    Williams, G.B.3
  • 105
    • 77957081349 scopus 로고    scopus 로고
    • Regional patterns of brain tissue loss associated with depression in Parkinson disease
    • Kostic VS, Agosta F, Petrovic I, et al. Regional patterns of brain tissue loss associated with depression in Parkinson disease. Neurology 2010;75(10):857-863.
    • (2010) Neurology , vol.75 , Issue.10 , pp. 857-863
    • Kostic, V.S.1    Agosta, F.2    Petrovic, I.3
  • 106
    • 84894522407 scopus 로고    scopus 로고
    • Visuoperceptive region atrophy independent of cognitive status in patients with Parkinson's disease with hallucinations
    • Goldman JG, Stebbins GT, Dinh V, et al. Visuoperceptive region atrophy independent of cognitive status in patients with Parkinson's disease with hallucinations. Brain 2014;137(3):849-859.
    • (2014) Brain , vol.137 , Issue.3 , pp. 849-859
    • Goldman, J.G.1    Stebbins, G.T.2    Dinh, V.3
  • 107
    • 70349263481 scopus 로고    scopus 로고
    • Metabolic brain networks in neurodegenerative disorders: a functional imaging approach
    • Eidelberg D. Metabolic brain networks in neurodegenerative disorders: a functional imaging approach. Trends Neurosci 2009;32(10):548-557.
    • (2009) Trends Neurosci , vol.32 , Issue.10 , pp. 548-557
    • Eidelberg, D.1
  • 108
    • 80051665062 scopus 로고    scopus 로고
    • Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study
    • Iranzo A, Valldeoriola F, Lomeña F, et al. Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. Lancet Neurol 2011;10(9):797-805.
    • (2011) Lancet Neurol , vol.10 , Issue.9 , pp. 797-805
    • Iranzo, A.1    Valldeoriola, F.2    Lomeña, F.3
  • 109
    • 28544434193 scopus 로고    scopus 로고
    • PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation
    • Adams JR. PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation. Brain 2005;128(12):2777-2785.
    • (2005) Brain , vol.128 , Issue.12 , pp. 2777-2785
    • Adams, J.R.1
  • 110
    • 84918841209 scopus 로고    scopus 로고
    • Correlation of striatal dopamine transporter imaging with post mortem substantia nigra cell counts
    • Kraemmer J, Kovacs GG, Perju-Dumbrava L, Pirker S, Traub-Weidinger T, Pirker W. Correlation of striatal dopamine transporter imaging with post mortem substantia nigra cell counts. Mov Disord 2014;29(14):1767-1773.
    • (2014) Mov Disord , vol.29 , Issue.14 , pp. 1767-1773
    • Kraemmer, J.1    Kovacs, G.G.2    Perju-Dumbrava, L.3    Pirker, S.4    Traub-Weidinger, T.5    Pirker, W.6
  • 111
    • 0027327049 scopus 로고
    • Human positron emission tomographic [18F]Fluorodopa studies correlate with dopamine cell counts and levels
    • Snow BJ, Tooyama I, McGeer EG, et al. Human positron emission tomographic [18F]Fluorodopa studies correlate with dopamine cell counts and levels. Ann Neurol 1993;34(3):324-330.
    • (1993) Ann Neurol , vol.34 , Issue.3 , pp. 324-330
    • Snow, B.J.1    Tooyama, I.2    McGeer, E.G.3
  • 112
    • 70350678559 scopus 로고    scopus 로고
    • Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study
    • Nandhagopal R, Kuramoto L, Schulzer M, et al. Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study. Brain 2009;132(11):2970-2979.
    • (2009) Brain , vol.132 , Issue.11 , pp. 2970-2979
    • Nandhagopal, R.1    Kuramoto, L.2    Schulzer, M.3
  • 113
    • 79955466566 scopus 로고    scopus 로고
    • Age-specific progression of nigrostriatal dysfunction in Parkinson's disease
    • de la Fuente-Fernández R, Schulzer M, Kuramoto L, et al. Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. Ann Neurol 2011;69(5):803-810.
    • (2011) Ann Neurol , vol.69 , Issue.5 , pp. 803-810
    • de la Fuente-Fernández, R.1    Schulzer, M.2    Kuramoto, L.3
  • 114
    • 3843057052 scopus 로고    scopus 로고
    • Changes of dopamine turnover in the progression of Parkinson's disease as measured by positron emission tomography: their relation to disease-compensatory mechanisms
    • Sossi V, de la Fuente-Fernandez Rl, Holden JE, Schulzer M, Ruth TJ, Stoessl J. Changes of dopamine turnover in the progression of Parkinson's disease as measured by positron emission tomography: their relation to disease-compensatory mechanisms. J Cereb Blood Flow Metab 2004;24(8):869-876.
    • (2004) J Cereb Blood Flow Metab , vol.24 , Issue.8 , pp. 869-876
    • Sossi, V.1    de la Fuente-Fernandez, R.2    Holden, J.E.3    Schulzer, M.4    Ruth, T.J.5    Stoessl, J.6
  • 115
    • 10344236071 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias
    • de la Fuente-Fernandez R. Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias. Brain 2004;127(12):2747-2754.
    • (2004) Brain , vol.127 , Issue.12 , pp. 2747-2754
    • de la Fuente-Fernandez, R.1
  • 116
    • 84896751626 scopus 로고    scopus 로고
    • Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients
    • Politis M, Wu K, Loane C, et al. Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients. J Clin Invest 2014;124(3):1340-1349.
    • (2014) J Clin Invest , vol.124 , Issue.3 , pp. 1340-1349
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 117
    • 0030727688 scopus 로고    scopus 로고
    • Alterations in opioid receptor binding in Parkinson's disease patients with levodopa-induced dyskinesias
    • Piccini P, Weeks RA, Brooks DJ. Alterations in opioid receptor binding in Parkinson's disease patients with levodopa-induced dyskinesias. Ann Neurol 1997;42(5):720-726.
    • (1997) Ann Neurol , vol.42 , Issue.5 , pp. 720-726
    • Piccini, P.1    Weeks, R.A.2    Brooks, D.J.3
  • 118
    • 79958163183 scopus 로고    scopus 로고
    • Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease
    • Ramlackhansingh AF, Bose SK, Ahmed I, Turkheimer FE, Pavese N, Brooks DJ. Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease. Neurology 2011;76(21):1811-1816.
    • (2011) Neurology , vol.76 , Issue.21 , pp. 1811-1816
    • Ramlackhansingh, A.F.1    Bose, S.K.2    Ahmed, I.3    Turkheimer, F.E.4    Pavese, N.5    Brooks, D.J.6
  • 119
    • 84952895163 scopus 로고    scopus 로고
    • Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease
    • Niccolini F, Foltynie T, Reis Marques T, et al. Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease. Brain 2015;138(10):3003-3015.
    • (2015) Brain , vol.138 , Issue.10 , pp. 3003-3015
    • Niccolini, F.1    Foltynie, T.2    Reis Marques, T.3
  • 120
    • 41149173996 scopus 로고    scopus 로고
    • The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years
    • Hely MA, Reid WGJ, Adena MA, Halliday GM, Morris JGL. The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov Disord 2008;23(6):837-844.
    • (2008) Mov Disord , vol.23 , Issue.6 , pp. 837-844
    • Hely, M.A.1    Reid, W.G.J.2    Adena, M.A.3    Halliday, G.M.4    Morris, J.G.L.5
  • 121
    • 0021739794 scopus 로고
    • Cerebral metabolic relationships for selected brain regions in Alzheimer's, Huntington's, and Parkinson's diseases
    • Metter EJ, Riege WH, Kameyama M, Kuhl DE, Phelps ME. Cerebral metabolic relationships for selected brain regions in Alzheimer's, Huntington's, and Parkinson's diseases. J Cereb Blood Flow Metab 1984;4:500-506.
    • (1984) J Cereb Blood Flow Metab , vol.4 , pp. 500-506
    • Metter, E.J.1    Riege, W.H.2    Kameyama, M.3    Kuhl, D.E.4    Phelps, M.E.5
  • 122
    • 82255170755 scopus 로고    scopus 로고
    • Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism
    • Pappata S, Santangelo G, Aarsland D, et al. Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism. Neurology 2011;77(14):1357-1362.
    • (2011) Neurology , vol.77 , Issue.14 , pp. 1357-1362
    • Pappata, S.1    Santangelo, G.2    Aarsland, D.3
  • 123
    • 79958141007 scopus 로고    scopus 로고
    • Cerebral glucose metabolic features of Parkinson disease and incident dementia: longitudinal study
    • Bohnen NI, Koeppe RA, Minoshima S, et al. Cerebral glucose metabolic features of Parkinson disease and incident dementia: longitudinal study. J Nuc Med 2011;52(6):848-855.
    • (2011) J Nuc Med , vol.52 , Issue.6 , pp. 848-855
    • Bohnen, N.I.1    Koeppe, R.A.2    Minoshima, S.3
  • 124
    • 54049100454 scopus 로고    scopus 로고
    • Imaging amyloid deposition in Lewy body diseases
    • Gomperts SN, Rentz DM, Moran E, et al. Imaging amyloid deposition in Lewy body diseases. Neurology 2008;71(12):903-910.
    • (2008) Neurology , vol.71 , Issue.12 , pp. 903-910
    • Gomperts, S.N.1    Rentz, D.M.2    Moran, E.3
  • 125
    • 56749185181 scopus 로고    scopus 로고
    • Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography
    • Edison P, Rowe CC, Rinne JO, et al. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. J Neurol Neurosurg Psychiatry 2008;79(12):1331-1338.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , Issue.12 , pp. 1331-1338
    • Edison, P.1    Rowe, C.C.2    Rinne, J.O.3
  • 126
    • 84990864318 scopus 로고    scopus 로고
    • Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration
    • Sanchez-Contreras M, Heckman MG, Tacik P, et al. Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration. Mov Disord 2016;32(1):115-123.
    • (2016) Mov Disord , vol.32 , Issue.1 , pp. 115-123
    • Sanchez-Contreras, M.1    Heckman, M.G.2    Tacik, P.3
  • 127
    • 33645078446 scopus 로고    scopus 로고
    • Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways
    • Hilker R, Thomas AV, Klein JC, et al. Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology 2005;65(11):1716-1722.
    • (2005) Neurology , vol.65 , Issue.11 , pp. 1716-1722
    • Hilker, R.1    Thomas, A.V.2    Klein, J.C.3
  • 128
    • 0038162372 scopus 로고    scopus 로고
    • Serotonin transporters in the midbrain of Parkinson's disease patients: a study with 123I-beta-CIT SPECT
    • Kim SE, Choi JY, Choe YS, Choi Y, Lee WY. Serotonin transporters in the midbrain of Parkinson's disease patients: a study with 123I-beta-CIT SPECT. J Nucl Med 2003;44(6):870-876.
    • (2003) J Nucl Med , vol.44 , Issue.6 , pp. 870-876
    • Kim, S.E.1    Choi, J.Y.2    Choe, Y.S.3    Choi, Y.4    Lee, W.Y.5
  • 129
    • 78650030521 scopus 로고    scopus 로고
    • Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures
    • Politis M, Wu K, Loane C, et al. Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures. Neurology 2010;75(21):1920-1927.
    • (2010) Neurology , vol.75 , Issue.21 , pp. 1920-1927
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 130
    • 20444477480 scopus 로고    scopus 로고
    • Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system
    • Remy P. Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain 2005;128(6):1314-1322.
    • (2005) Brain , vol.128 , Issue.6 , pp. 1314-1322
    • Remy, P.1
  • 131
    • 84910622554 scopus 로고    scopus 로고
    • Imaging the aetiology of sleep disorders in dementia and Parkinson's disease
    • Pavese N. Imaging the aetiology of sleep disorders in dementia and Parkinson's disease. Curr Neurol Neurosci Rep 2014;14(12):501.
    • (2014) Curr Neurol Neurosci Rep , vol.14 , Issue.12 , pp. 501
    • Pavese, N.1
  • 132
    • 0041883808 scopus 로고    scopus 로고
    • [18F]fluorodopa uptake in the upper brainstem measured with positron emission tomography correlates with decreased REM sleep duration in early Parkinson's disease
    • Hilker R, Razai N, Ghaemi M, et al. [18F]fluorodopa uptake in the upper brainstem measured with positron emission tomography correlates with decreased REM sleep duration in early Parkinson's disease. Clin Neurol Neurosurg 2003;105(4):262-269.
    • (2003) Clin Neurol Neurosurg , vol.105 , Issue.4 , pp. 262-269
    • Hilker, R.1    Razai, N.2    Ghaemi, M.3
  • 133
    • 33744509517 scopus 로고    scopus 로고
    • Does cardiac metaiodobenzylguanidine (MIBG) uptake in Parkinson's disease correlate with major autonomic symptoms?
    • Matsui H, Nishinaka K, Oda M, Komatsu K, Kubori T, Udaka F. Does cardiac metaiodobenzylguanidine (MIBG) uptake in Parkinson's disease correlate with major autonomic symptoms? Parkinsonism Relat Disord 2006;12(5):284-288.
    • (2006) Parkinsonism Relat Disord , vol.12 , Issue.5 , pp. 284-288
    • Matsui, H.1    Nishinaka, K.2    Oda, M.3    Komatsu, K.4    Kubori, T.5    Udaka, F.6
  • 134
    • 0025298139 scopus 로고
    • Primate models of movement disorders of basal ganglia origin
    • DeLong MR. Primate models of movement disorders of basal ganglia origin. Trends Neurosci 1990;13(7):281-285.
    • (1990) Trends Neurosci , vol.13 , Issue.7 , pp. 281-285
    • DeLong, M.R.1
  • 135
    • 0025301385 scopus 로고
    • Disinhibition as a basic process in the expression of striatal functions
    • Chevalier G, Deniau JM. Disinhibition as a basic process in the expression of striatal functions. Trends Neurosci 1990;13(7):277-280.
    • (1990) Trends Neurosci , vol.13 , Issue.7 , pp. 277-280
    • Chevalier, G.1    Deniau, J.M.2
  • 136
    • 85010441104 scopus 로고    scopus 로고
    • Oscillatory activity in the basal ganglia and deep brain stimulation
    • Guridi J, Alegre M. Oscillatory activity in the basal ganglia and deep brain stimulation. Mov Disord 2016;32(1):64-69.
    • (2016) Mov Disord , vol.32 , Issue.1 , pp. 64-69
    • Guridi, J.1    Alegre, M.2
  • 137
    • 85059565925 scopus 로고    scopus 로고
    • Motor complications in Parkinson's disease: molecular and electrophysiological mechanisms of dyskinesias
    • Piconi B, Hernandez L, Obeso JA, Calabresi P. Motor complications in Parkinson's disease: molecular and electrophysiological mechanisms of dyskinesias. Mov Disord 2017;32.
    • (2017) Mov Disord , vol.32
    • Piconi, B.1    Hernandez, L.2    Obeso, J.A.3    Calabresi, P.4
  • 138
    • 84994227079 scopus 로고    scopus 로고
    • Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson's disease
    • Neumann W-J, Degen K, Schneider G-H, et al. Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson's disease. Mov Disord 2016;31(11):1748-1751.
    • (2016) Mov Disord , vol.31 , Issue.11 , pp. 1748-1751
    • Neumann, W.-J.1    Degen, K.2    Schneider, G.-H.3
  • 139
    • 78650709327 scopus 로고    scopus 로고
    • Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease
    • Rodriguez-Oroz MC, Lopez-Azcarate J, Garcia-Garcia D, et al. Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease. Brain 2010;134(1):36-49.
    • (2010) Brain , vol.134 , Issue.1 , pp. 36-49
    • Rodriguez-Oroz, M.C.1    Lopez-Azcarate, J.2    Garcia-Garcia, D.3
  • 140
    • 84935102415 scopus 로고    scopus 로고
    • The relative phases of basal ganglia activities dynamically shape effective connectivity in Parkinson's disease
    • Cagnan H, Duff EP, Brown P. The relative phases of basal ganglia activities dynamically shape effective connectivity in Parkinson's disease. Brain 2015;138(6):1667-1678.
    • (2015) Brain , vol.138 , Issue.6 , pp. 1667-1678
    • Cagnan, H.1    Duff, E.P.2    Brown, P.3
  • 141
    • 0344440902 scopus 로고    scopus 로고
    • A new dynamic model of the cortico-basal ganglia loop
    • Nambu A. A new dynamic model of the cortico-basal ganglia loop. Prog Brain Res 2004;143:461-466.
    • (2004) Prog Brain Res , vol.143 , pp. 461-466
    • Nambu, A.1
  • 142
    • 84893419280 scopus 로고    scopus 로고
    • The thalamostriatal system in normal and diseased states
    • Smith Y, Galvan A, Ellender TJ, et al. The thalamostriatal system in normal and diseased states. Front Syst Neurosci 2014;8:5.
    • (2014) Front Syst Neurosci , vol.8 , pp. 5
    • Smith, Y.1    Galvan, A.2    Ellender, T.J.3
  • 143
    • 84992592992 scopus 로고    scopus 로고
    • Pedunculopontine nucleus region deep brain stimulation in Parkinson disease: surgical techniques, side effects, and postoperative imaging
    • Hamani C, Lozano AM, Mazzone PAM, et al. Pedunculopontine nucleus region deep brain stimulation in Parkinson disease: surgical techniques, side effects, and postoperative imaging. Stereotact Funct Neurosurg 2016;94(5):307-319.
    • (2016) Stereotact Funct Neurosurg , vol.94 , Issue.5 , pp. 307-319
    • Hamani, C.1    Lozano, A.M.2    Mazzone, P.A.M.3
  • 144
    • 84941367191 scopus 로고    scopus 로고
    • Dopamine is required for the neural representation and control of movement vigor
    • Panigrahi B, Martin KA, Li Y, et al. Dopamine is required for the neural representation and control of movement vigor. Cell 2015;162(6):1418-1430.
    • (2015) Cell , vol.162 , Issue.6 , pp. 1418-1430
    • Panigrahi, B.1    Martin, K.A.2    Li, Y.3
  • 146
    • 84879494743 scopus 로고    scopus 로고
    • Exposure to pesticides or solvents and risk of Parkinson disease
    • Pezzoli G, Cereda E. Exposure to pesticides or solvents and risk of Parkinson disease. Neurology 2013;80(22):2035-2041.
    • (2013) Neurology , vol.80 , Issue.22 , pp. 2035-2041
    • Pezzoli, G.1    Cereda, E.2
  • 147
    • 84902475826 scopus 로고    scopus 로고
    • The disease intersection of susceptibility and exposure: Chemical exposures and neurodegenerative disease risk
    • Tanner CM, Goldman SM, Ross GW, Grate SJ. The disease intersection of susceptibility and exposure: Chemical exposures and neurodegenerative disease risk. Alzheimers Dement 2014;10(3):S213-S225.
    • (2014) Alzheimers Dement , vol.10 , Issue.3 , pp. S213-S225
    • Tanner, C.M.1    Goldman, S.M.2    Ross, G.W.3    Grate, S.J.4
  • 148
    • 84891866326 scopus 로고    scopus 로고
    • Environmental toxins and Parkinson's disease
    • Goldman SM. Environmental toxins and Parkinson's disease. Annu Rev Pharmacol Toxicol 2014;54(1):141-164.
    • (2014) Annu Rev Pharmacol Toxicol , vol.54 , Issue.1 , pp. 141-164
    • Goldman, S.M.1
  • 149
    • 84911422499 scopus 로고    scopus 로고
    • Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease
    • Furlong M, Tanner CM, Goldman SM, et al. Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease. Environ Int 2015;75:144-150.
    • (2015) Environ Int , vol.75 , pp. 144-150
    • Furlong, M.1    Tanner, C.M.2    Goldman, S.M.3
  • 150
    • 84870356279 scopus 로고    scopus 로고
    • Polychlorinated biphenyls in prospectively collected serum and Parkinson's disease risk
    • Weisskopf MG, Knekt P, O'Reilly EJ, et al. Polychlorinated biphenyls in prospectively collected serum and Parkinson's disease risk. Mov Disord 2012;27(13):1659-1665.
    • (2012) Mov Disord , vol.27 , Issue.13 , pp. 1659-1665
    • Weisskopf, M.G.1    Knekt, P.2    O'Reilly, E.J.3
  • 151
    • 34447255185 scopus 로고    scopus 로고
    • Pooled analysis of tobacco use and risk of Parkinson disease
    • Ritz B, Ascherio A, Checkoway H, et al. Pooled analysis of tobacco use and risk of Parkinson disease. Arch Neurol 2007;64(7):990-997.
    • (2007) Arch Neurol , vol.64 , Issue.7 , pp. 990-997
    • Ritz, B.1    Ascherio, A.2    Checkoway, H.3
  • 152
    • 33749487587 scopus 로고    scopus 로고
    • NOS2A and the modulating effect of cigarette smoking in Parkinson's disease
    • Hancock DB, Martin ER, Fujiwara K, et al. NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. Ann Neurol 2006;60(3):366-373.
    • (2006) Ann Neurol , vol.60 , Issue.3 , pp. 366-373
    • Hancock, D.B.1    Martin, E.R.2    Fujiwara, K.3
  • 153
    • 84866293285 scopus 로고    scopus 로고
    • Caffeine and risk of Parkinson's disease in a large cohort of men and women
    • Palacios N, Gao X, McCullough ML, et al. Caffeine and risk of Parkinson's disease in a large cohort of men and women. Mov Disord 2012;27(10):1276-1282.
    • (2012) Mov Disord , vol.27 , Issue.10 , pp. 1276-1282
    • Palacios, N.1    Gao, X.2    McCullough, M.L.3
  • 154
    • 85017453277 scopus 로고    scopus 로고
    • Coffee, genetic variants, and Parkinson's disease: gene–environment interactions
    • Yamada-Fowler N, Söderkvist P. Coffee, genetic variants, and Parkinson's disease: gene–environment interactions. J Caffeine Res 2015;5(1):3-10.
    • (2015) J Caffeine Res , vol.5 , Issue.1 , pp. 3-10
    • Yamada-Fowler, N.1    Söderkvist, P.2
  • 156
    • 84963550642 scopus 로고    scopus 로고
    • Nomenclature of genetic movement disorders: recommendations of the International Parkinson and Movement Disorder Society Task Force
    • Marras C, Lang A, van de Warrenburg BP, et al. Nomenclature of genetic movement disorders: recommendations of the International Parkinson and Movement Disorder Society Task Force. Mov Disord 2016;31(4):436-457.
    • (2016) Mov Disord , vol.31 , Issue.4 , pp. 436-457
    • Marras, C.1    Lang, A.2    van de Warrenburg, B.P.3
  • 157
    • 84962081972 scopus 로고    scopus 로고
    • A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
    • Walsh DM, Selkoe DJ. A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration. Nat Rev Neurosci 2016;17(4):251-260.
    • (2016) Nat Rev Neurosci , vol.17 , Issue.4 , pp. 251-260
    • Walsh, D.M.1    Selkoe, D.J.2
  • 158
    • 8844266996 scopus 로고    scopus 로고
    • Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
    • Paisán-Ruíz C, Jain S, Evans EW, et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004;44(4):595-600.
    • (2004) Neuron , vol.44 , Issue.4 , pp. 595-600
    • Paisán-Ruíz, C.1    Jain, S.2    Evans, E.W.3
  • 159
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44(4):601-607.
    • (2004) Neuron , vol.44 , Issue.4 , pp. 601-607
    • Zimprich, A.1    Biskup, S.2    Leitner, P.3
  • 160
    • 28544441389 scopus 로고    scopus 로고
    • Genetics of Parkinson's disease: LRRK2 on the rise
    • Brice A. Genetics of Parkinson's disease: LRRK2 on the rise. Brain 2005;128(12):2760-2762.
    • (2005) Brain , vol.128 , Issue.12 , pp. 2760-2762
    • Brice, A.1
  • 161
    • 50049104725 scopus 로고    scopus 로고
    • Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
    • Healy DG, Falchi M, O'Sullivan SS, et al. Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol 2008;7(7):583-590.
    • (2008) Lancet Neurol , vol.7 , Issue.7 , pp. 583-590
    • Healy, D.G.1    Falchi, M.2    O'Sullivan, S.S.3
  • 163
    • 80051534540 scopus 로고    scopus 로고
    • A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease
    • Zimprich A, Benet-Pagès A, Struhal W, et al. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet 2011;89(1):168-175.
    • (2011) Am J Hum Genet , vol.89 , Issue.1 , pp. 168-175
    • Zimprich, A.1    Benet-Pagès, A.2    Struhal, W.3
  • 164
    • 84898057951 scopus 로고    scopus 로고
    • Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease
    • Berg D, Postuma RB, Bloem B, et al. Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease. Mov Disord 2014;29(4):454-462.
    • (2014) Mov Disord , vol.29 , Issue.4 , pp. 454-462
    • Berg, D.1    Postuma, R.B.2    Bloem, B.3
  • 165
    • 84939599004 scopus 로고    scopus 로고
    • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
    • Nalls MA, Pankratz N, Lill CM, et al. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat Genet 2014;46(9):989-993.
    • (2014) Nat Genet , vol.46 , Issue.9 , pp. 989-993
    • Nalls, M.A.1    Pankratz, N.2    Lill, C.M.3
  • 166
    • 84946596735 scopus 로고    scopus 로고
    • Flies with Parkinson's disease
    • Vanhauwaert R, Verstreken P. Flies with Parkinson's disease. Exp Neurol 2015;274:42-51.
    • (2015) Exp Neurol , vol.274 , pp. 42-51
    • Vanhauwaert, R.1    Verstreken, P.2
  • 167
    • 84861983560 scopus 로고    scopus 로고
    • Vitamin K2 is a mitochondrial electron carrier that rescues Pink1 deficiency
    • Vos M, Esposito G, Edirisinghe JN, et al. Vitamin K2 is a mitochondrial electron carrier that rescues Pink1 deficiency. Science 2012;336(6086):1306-1310.
    • (2012) Science , vol.336 , Issue.6086 , pp. 1306-1310
    • Vos, M.1    Esposito, G.2    Edirisinghe, J.N.3
  • 168
    • 84959235101 scopus 로고    scopus 로고
    • Genetics of movement disorders in the next-generation sequencing era
    • Olgiati S, Quadri M, Bonifati V. Genetics of movement disorders in the next-generation sequencing era. Mov Disord 2016;31(4):458-470.
    • (2016) Mov Disord , vol.31 , Issue.4 , pp. 458-470
    • Olgiati, S.1    Quadri, M.2    Bonifati, V.3
  • 169
    • 0014208039 scopus 로고
    • Aromatic amino acids and modification of parkinsonism
    • Cotzias GC, Van Woert MH, Schiffer LM. Aromatic amino acids and modification of parkinsonism. N Engl J Med 1967;276(7):374-379.
    • (1967) N Engl J Med , vol.276 , Issue.7 , pp. 374-379
    • Cotzias, G.C.1    Van Woert, M.H.2    Schiffer, L.M.3
  • 171
    • 84958749002 scopus 로고    scopus 로고
    • New and emerging medical therapies in Parkinson's disease
    • Lotia M, Jankovic J. New and emerging medical therapies in Parkinson's disease. Expert Opin Pharmacother 2016;17(7):895-909.
    • (2016) Expert Opin Pharmacother , vol.17 , Issue.7 , pp. 895-909
    • Lotia, M.1    Jankovic, J.2
  • 172
    • 84991110347 scopus 로고    scopus 로고
    • Novel levodopa formulations for Parkinson's disease
    • Freitas ME, Ruiz-Lopez M, Fox SH. Novel levodopa formulations for Parkinson's disease. CNS Drug 2016;30(11):1079-1095.
    • (2016) CNS Drug , vol.30 , Issue.11 , pp. 1079-1095
    • Freitas, M.E.1    Ruiz-Lopez, M.2    Fox, S.H.3
  • 173
    • 84982156297 scopus 로고    scopus 로고
    • Levodopa therapy for Parkinson disease: a look backward and forward
    • LeWitt PA, Fahn S. Levodopa therapy for Parkinson disease: a look backward and forward. Neurology 2016;86(14 suppl. 1):S3-S12.
    • (2016) Neurology , vol.86 , Issue.14 , pp. S3-S12
    • LeWitt, P.A.1    Fahn, S.2
  • 174
    • 84920870768 scopus 로고    scopus 로고
    • Levodopa: effect on cell death and the natural history of Parkinson's disease
    • Olanow CW. Levodopa: effect on cell death and the natural history of Parkinson's disease. Mov Disord 2014;30(1):37-44.
    • (2014) Mov Disord , vol.30 , Issue.1 , pp. 37-44
    • Olanow, C.W.1
  • 175
    • 19744378296 scopus 로고    scopus 로고
    • Levodopa and the progression of Parkinson's disease
    • Parkinson Study Group. Levodopa and the progression of Parkinson's disease. N Engl J Med 2004;351(24):2498-2508.
    • (2004) N Engl J Med , vol.351 , Issue.24 , pp. 2498-2508
  • 176
    • 84955179896 scopus 로고    scopus 로고
    • Clinical and scientific perspectives on movement disorders: Stanley Fahn's contributions
    • Jankovic J, Bressman S, Dauer W, Kang U. Clinical and scientific perspectives on movement disorders: Stanley Fahn's contributions. Mov Disord 2015;30(1):1862-1869.
    • (2015) Mov Disord , vol.30 , Issue.1 , pp. 1862-1869
    • Jankovic, J.1    Bressman, S.2    Dauer, W.3    Kang, U.4
  • 177
    • 84964335015 scopus 로고    scopus 로고
    • Drug-induced dyskinesia, part 1: treatment of levodopa-induced dyskinesia
    • Vijayakumar D, Jankovic J. Drug-induced dyskinesia, part 1: treatment of levodopa-induced dyskinesia. Drugs 2016;76(7):759-777.
    • (2016) Drugs , vol.76 , Issue.7 , pp. 759-777
    • Vijayakumar, D.1    Jankovic, J.2
  • 178
    • 84928609688 scopus 로고    scopus 로고
    • Clinical spectrum of levodopa-induced complications
    • Aquino CC, Fox SH. Clinical spectrum of levodopa-induced complications. Mov Disord 2014;30(1):80-89.
    • (2014) Mov Disord , vol.30 , Issue.1 , pp. 80-89
    • Aquino, C.C.1    Fox, S.H.2
  • 179
    • 9044226896 scopus 로고    scopus 로고
    • Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa
    • Parkinson Study Group. Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa. Ann Neurol 1996;39(1):37-45.
    • (1996) Ann Neurol , vol.39 , Issue.1 , pp. 37-45
  • 180
    • 0026551551 scopus 로고
    • Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification
    • Luquin MR, Scipioni O, Vaamonde J, Gershanik O, Obeso JA. Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification. Mov Disord 1992;7(2):117-124.
    • (1992) Mov Disord , vol.7 , Issue.2 , pp. 117-124
    • Luquin, M.R.1    Scipioni, O.2    Vaamonde, J.3    Gershanik, O.4    Obeso, J.A.5
  • 181
    • 0001417980 scopus 로고
    • Surgical procedure for postencephalitic tremor, with notes on the physiology of the premotor fibers
    • Myers RH. Surgical procedure for postencephalitic tremor, with notes on the physiology of the premotor fibers. Arch Neurol Psychiatry 1940;44:445-459.
    • (1940) Arch Neurol Psychiatry , vol.44 , pp. 445-459
    • Myers, R.H.1
  • 182
    • 34250910669 scopus 로고
    • Ligation of the anterior choroidal artery for involuntary movements; parkinsonism
    • Cooper IS. Ligation of the anterior choroidal artery for involuntary movements; parkinsonism. Psychiatr Q 1953;27(2):317-319.
    • (1953) Psychiatr Q , vol.27 , Issue.2 , pp. 317-319
    • Cooper, I.S.1
  • 183
    • 0001479907 scopus 로고
    • Chemopallidectomy and chemothalamectomy
    • Cooper IS, Bravo G. Chemopallidectomy and chemothalamectomy. J Neurosurg 1958;15(3):244-250.
    • (1958) J Neurosurg , vol.15 , Issue.3 , pp. 244-250
    • Cooper, I.S.1    Bravo, G.2
  • 184
    • 0026536547 scopus 로고
    • Leksell's posteroventral pallidotomy in the treatment of Parkinson's disease
    • Laitinen LV, Bergenheim AT, Hariz MI. Leksell's posteroventral pallidotomy in the treatment of Parkinson's disease. J Neurosurg 1992;76(1):53-61.
    • (1992) J Neurosurg , vol.76 , Issue.1 , pp. 53-61
    • Laitinen, L.V.1    Bergenheim, A.T.2    Hariz, M.I.3
  • 185
    • 72849166333 scopus 로고
    • Treatment of parkinsonism by stereotactic thermolesions in the pallidal region. A clinical evaluation of 81 cases
    • Svennilson E, Torvik A, Lowe R, Leksell L. Treatment of parkinsonism by stereotactic thermolesions in the pallidal region. A clinical evaluation of 81 cases. Acta Psychiatrica Scandinavica 1960;35(3):358-377.
    • (1960) Acta Psychiatrica Scandinavica , vol.35 , Issue.3 , pp. 358-377
    • Svennilson, E.1    Torvik, A.2    Lowe, R.3    Leksell, L.4
  • 186
    • 85010468251 scopus 로고    scopus 로고
    • Advances in surgery for movement disorders
    • Rowland NC, Sammartino F, Lozano AM. Advances in surgery for movement disorders. Mov Disord 2016;32(1):5-10.
    • (2016) Mov Disord , vol.32 , Issue.1 , pp. 5-10
    • Rowland, N.C.1    Sammartino, F.2    Lozano, A.M.3
  • 187
    • 0027315807 scopus 로고
    • [Effects of the stimulation of the subthalamic nucleus in Parkinson disease]
    • Pollak P, Benabid AL, Gross C, et al. [Effects of the stimulation of the subthalamic nucleus in Parkinson disease]. Rev Neurol (Paris) 1993;149(3):175-176.
    • (1993) Rev Neurol (Paris) , vol.149 , Issue.3 , pp. 175-176
    • Pollak, P.1    Benabid, A.L.2    Gross, C.3
  • 188
    • 0000089940 scopus 로고
    • Intracranial self-stimulation in man
    • Bishop MP, Elder ST, Heath RG. Intracranial self-stimulation in man. Science 1963;140(3565):394-396.
    • (1963) Science , vol.140 , Issue.3565 , pp. 394-396
    • Bishop, M.P.1    Elder, S.T.2    Heath, R.G.3
  • 189
    • 84873286010 scopus 로고    scopus 로고
    • Probing and regulating dysfunctional circuits using deep brain stimulation
    • Lozano AM, Lipsman N. Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron 2013;77(3):406-424.
    • (2013) Neuron , vol.77 , Issue.3 , pp. 406-424
    • Lozano, A.M.1    Lipsman, N.2
  • 190
    • 0001875646 scopus 로고
    • Early experiences with ultrasonic irradiation of the pallidofugal and nigral complexes in hyperkinetic and hypertonic disorders
    • Meyers R, Fry WJ, Fry FJ, Dreyer LL, Schultz DF, Noyes RF. Early experiences with ultrasonic irradiation of the pallidofugal and nigral complexes in hyperkinetic and hypertonic disorders. J Neurosurg 1959;16(1):32-54.
    • (1959) J Neurosurg , vol.16 , Issue.1 , pp. 32-54
    • Meyers, R.1    Fry, W.J.2    Fry, F.J.3    Dreyer, L.L.4    Schultz, D.F.5    Noyes, R.F.6
  • 191
    • 84876485354 scopus 로고    scopus 로고
    • MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study
    • Lipsman N, Schwartz ML, Huang Y, et al. MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study. Lancet Neurol 2013;12(5):462-468.
    • (2013) Lancet Neurol , vol.12 , Issue.5 , pp. 462-468
    • Lipsman, N.1    Schwartz, M.L.2    Huang, Y.3
  • 192
    • 84984694311 scopus 로고    scopus 로고
    • A randomized trial of focused ultrasound thalamotomy for essential tremor
    • Elias WJ, Lipsman N, Ondo WG, et al. A randomized trial of focused ultrasound thalamotomy for essential tremor. N Engl J Med 2016;375(8):730-739.
    • (2016) N Engl J Med , vol.375 , Issue.8 , pp. 730-739
    • Elias, W.J.1    Lipsman, N.2    Ondo, W.G.3
  • 193
    • 84963784593 scopus 로고    scopus 로고
    • Focus ultrasound therapy for movement disorders: current data and expected developments
    • Weintraub D, Elias WJ. Focus ultrasound therapy for movement disorders: current data and expected developments. Mov Disord 2017;32:20-27.
    • (2017) Mov Disord , vol.32 , pp. 20-27
    • Weintraub, D.1    Elias, W.J.2
  • 194
    • 0031740582 scopus 로고    scopus 로고
    • Consensus statement of the Movement Disorder Society on tremor
    • Deuschl G, Bain P, Brin M. Consensus statement of the Movement Disorder Society on tremor. Mov Disord 2008;13(S3):2-23.
    • (2008) Mov Disord , vol.13 , Issue.S3 , pp. 2-23
    • Deuschl, G.1    Bain, P.2    Brin, M.3
  • 195
    • 33750975077 scopus 로고    scopus 로고
    • Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study
    • Pavese N, Evans AH, Tai YF, et al. Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study. Neurology 2006;67(9):1612-1617.
    • (2006) Neurology , vol.67 , Issue.9 , pp. 1612-1617
    • Pavese, N.1    Evans, A.H.2    Tai, Y.F.3
  • 196
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
    • Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55(3):181-184.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , Issue.3 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4
  • 197
    • 84947875160 scopus 로고    scopus 로고
    • Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease
    • Qamhawi Z, Towey D, Shah B, et al. Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease. Brain 2015;138(10):2964-2973.
    • (2015) Brain , vol.138 , Issue.10 , pp. 2964-2973
    • Qamhawi, Z.1    Towey, D.2    Shah, B.3
  • 198
    • 0026636355 scopus 로고
    • Dopamine, tremor, and Parkinson's disease
    • Hirsch E. Dopamine, tremor, and Parkinson's disease. Lancet 1992;340(8811):125-126.
    • (1992) Lancet , vol.340 , Issue.8811 , pp. 125-126
    • Hirsch, E.1
  • 199
    • 0032588334 scopus 로고    scopus 로고
    • Post mortem studies in Parkinson's disease—is it possible to detect brain areas for specific symptoms?
    • Jellinger KA. Post mortem studies in Parkinson's disease—is it possible to detect brain areas for specific symptoms? J Neural Transm 1999;56:1-29.
    • (1999) J Neural Transm , vol.56 , pp. 1-29
    • Jellinger, K.A.1
  • 200
    • 79953267610 scopus 로고    scopus 로고
    • Akinetic-rigid and tremor-dominant Parkinson's disease patients show different patterns of FP-CIT single photon emission computed tomography
    • Eggers C, Kahraman D, Fink GR, Schmidt M, Timmermann L. Akinetic-rigid and tremor-dominant Parkinson's disease patients show different patterns of FP-CIT single photon emission computed tomography. Mov Disord 2011;26:416-423.
    • (2011) Mov Disord , vol.26 , pp. 416-423
    • Eggers, C.1    Kahraman, D.2    Fink, G.R.3    Schmidt, M.4    Timmermann, L.5
  • 202
    • 0034668905 scopus 로고    scopus 로고
    • Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and the tremulous 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine vervet model of parkinsonism
    • Raz A, Vaadia E, Bergman H. Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and the tremulous 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine vervet model of parkinsonism. J Neurosci 2000;20(22):8559-8571.
    • (2000) J Neurosci , vol.20 , Issue.22 , pp. 8559-8571
    • Raz, A.1    Vaadia, E.2    Bergman, H.3
  • 203
    • 84856920646 scopus 로고    scopus 로고
    • Oscillating central motor networks in pathological tremors and voluntary movements. What makes the difference?
    • Muthuraman M, Heute U, Arning K, et al. Oscillating central motor networks in pathological tremors and voluntary movements. What makes the difference? NeuroImage 2012;60(2):1331-1339.
    • (2012) NeuroImage , vol.60 , Issue.2 , pp. 1331-1339
    • Muthuraman, M.1    Heute, U.2    Arning, K.3
  • 204
    • 78649687189 scopus 로고    scopus 로고
    • Parkinson's disease tremor-related metabolic network: Characterization, progression, and treatment effects
    • Mure H, Hirano S, Tang CC, et al. Parkinson's disease tremor-related metabolic network: Characterization, progression, and treatment effects. NeuroImage 2011;54(2):1244-1253.
    • (2011) NeuroImage , vol.54 , Issue.2 , pp. 1244-1253
    • Mure, H.1    Hirano, S.2    Tang, C.C.3
  • 205
    • 0036929017 scopus 로고    scopus 로고
    • Pathophysiology of Parkinson's disease: from clinical neurology to basic neuroscience and back
    • Bergman H, Deuschl GN. Pathophysiology of Parkinson's disease: from clinical neurology to basic neuroscience and back. Mov Disord 2002;17(S3):S28-S40.
    • (2002) Mov Disord , vol.17 , Issue.S3 , pp. S28-S40
    • Bergman, H.1    Deuschl, G.N.2
  • 207
    • 0024239764 scopus 로고
    • The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function
    • Llinas R. The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science 1988;242(4886):1654-1664.
    • (1988) Science , vol.242 , Issue.4886 , pp. 1654-1664
    • Llinas, R.1
  • 208
    • 0032032372 scopus 로고    scopus 로고
    • Patterns of bursting occurring in thalamic cells during parkinsonian tremor
    • Zirh TA, Lenz FA, Reich SG, Dougherty PM. Patterns of bursting occurring in thalamic cells during parkinsonian tremor. Neuroscience 1998;83(1):107-121.
    • (1998) Neuroscience , vol.83 , Issue.1 , pp. 107-121
    • Zirh, T.A.1    Lenz, F.A.2    Reich, S.G.3    Dougherty, P.M.4
  • 209
    • 0033549810 scopus 로고    scopus 로고
    • A basal ganglia pacemaker formed by the subthalamic nucleus and dexternal globus pallidus
    • Plenz D, Kital ST. A basal ganglia pacemaker formed by the subthalamic nucleus and dexternal globus pallidus. Nature 1999;400(6745):677-682.
    • (1999) Nature , vol.400 , Issue.6745 , pp. 677-682
    • Plenz, D.1    Kital, S.T.2
  • 210
    • 0038719645 scopus 로고    scopus 로고
    • Functional correlations between neighboring neurons in the primate globus pallidus are weak or nonexistent
    • Bar-Gad I, Heimer G, Ritov Y, Bergman H. Functional correlations between neighboring neurons in the primate globus pallidus are weak or nonexistent. J Neurosci 2003;23(10):4012-4016.
    • (2003) J Neurosci , vol.23 , Issue.10 , pp. 4012-4016
    • Bar-Gad, I.1    Heimer, G.2    Ritov, Y.3    Bergman, H.4
  • 211
    • 84872729641 scopus 로고    scopus 로고
    • Parkinson's disease and parkinsonism: neuropathology
    • Dickson DW. Parkinson's disease and parkinsonism: neuropathology. Cold Spring Harb Perspect Med 2012;2(8):a009258-a009258.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , Issue.8 , pp. a009258
    • Dickson, D.W.1
  • 212
    • 84905856405 scopus 로고    scopus 로고
    • Accuracy of Parkinson disease diagnosis unchanged in 2 decades
    • Rajput AH, Rajput A. Accuracy of Parkinson disease diagnosis unchanged in 2 decades. Neurology 2014;83(5):386-387.
    • (2014) Neurology , vol.83 , Issue.5 , pp. 386-387
    • Rajput, A.H.1    Rajput, A.2
  • 213
    • 84963811810 scopus 로고    scopus 로고
    • Motor and nonmotor features of carriers of the p.A53T alpha-synuclein mutation: a longitudinal study
    • Papadimitriou D, Antonelou R, Miligkos M, et al. Motor and nonmotor features of carriers of the p.A53T alpha-synuclein mutation: a longitudinal study. Mov Disord 2016;31(8):1226-1230.
    • (2016) Mov Disord , vol.31 , Issue.8 , pp. 1226-1230
    • Papadimitriou, D.1    Antonelou, R.2    Miligkos, M.3
  • 214
    • 77955058912 scopus 로고    scopus 로고
    • A historical analysis of the relationship between encephalitis lethargica and postencephalitic parkinsonism: a complex rather than a direct relationship
    • Vilensky JA, Gilman S, McCall S. A historical analysis of the relationship between encephalitis lethargica and postencephalitic parkinsonism: a complex rather than a direct relationship. Mov Disord 2010;25(9):1116-1123.
    • (2010) Mov Disord , vol.25 , Issue.9 , pp. 1116-1123
    • Vilensky, J.A.1    Gilman, S.2    McCall, S.3
  • 215
    • 84929654369 scopus 로고    scopus 로고
    • Parkinsonism following neuroleptic exposure: a double-hit hypothesis?
    • Erro R, Bhatia KP, Tinazzi M. Parkinsonism following neuroleptic exposure: a double-hit hypothesis? Mov Disord 2015;30(6):780-785.
    • (2015) Mov Disord , vol.30 , Issue.6 , pp. 780-785
    • Erro, R.1    Bhatia, K.P.2    Tinazzi, M.3
  • 216
    • 84929655014 scopus 로고    scopus 로고
    • Genetic risk loci for Parkinson's disease: moving from state to trait?
    • Kasten M, Klein C. Genetic risk loci for Parkinson's disease: moving from state to trait? Mov Disord 2015;30(6):747-749.
    • (2015) Mov Disord , vol.30 , Issue.6 , pp. 747-749
    • Kasten, M.1    Klein, C.2
  • 217
    • 84943806397 scopus 로고    scopus 로고
    • Pathways to parkinsonism redux: convergent pathobiological mechanisms in genetics of Parkinson's disease
    • Kumaran R, Cookson MR. Pathways to parkinsonism redux: convergent pathobiological mechanisms in genetics of Parkinson's disease. Hum Mol Genet 2015;24(R1):R32-R44.
    • (2015) Hum Mol Genet , vol.24 , Issue.R1 , pp. R32-R44
    • Kumaran, R.1    Cookson, M.R.2
  • 218
    • 84855925916 scopus 로고    scopus 로고
    • Toward a redefinition of Parkinson's disease
    • Stern MB, Lang A, Poewe W. Toward a redefinition of Parkinson's disease. Mov Disord 2012;27(1):54-60.
    • (2012) Mov Disord , vol.27 , Issue.1 , pp. 54-60
    • Stern, M.B.1    Lang, A.2    Poewe, W.3
  • 219
    • 84876464458 scopus 로고    scopus 로고
    • Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities
    • Berg D, Lang AE, Postuma RB, et al. Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities. Lancet Neurol 2013;12(5):514-524.
    • (2013) Lancet Neurol , vol.12 , Issue.5 , pp. 514-524
    • Berg, D.1    Lang, A.E.2    Postuma, R.B.3
  • 220
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: substantia nigra regional selectivity
    • Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991;114(5):2283-2301.
    • (1991) Brain , vol.114 , Issue.5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 221
    • 84861561293 scopus 로고    scopus 로고
    • How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder
    • Postuma RB, Lang AE, Gagnon JF, Pelletier A, Montplaisir JY. How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder. Brain 2012;135(6):1860-1870.
    • (2012) Brain , vol.135 , Issue.6 , pp. 1860-1870
    • Postuma, R.B.1    Lang, A.E.2    Gagnon, J.F.3    Pelletier, A.4    Montplaisir, J.Y.5
  • 222
    • 77953021942 scopus 로고    scopus 로고
    • Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
    • Beach TG, Adler CH, Sue LI, et al. Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol 2010;119(6):689-702.
    • (2010) Acta Neuropathol , vol.119 , Issue.6 , pp. 689-702
    • Beach, T.G.1    Adler, C.H.2    Sue, L.I.3
  • 223
    • 84859846991 scopus 로고    scopus 로고
    • Defining at-risk populations for Parkinson's disease: lessons from ongoing studies
    • Berg D, Marek K, Ross GW, Poewe W. Defining at-risk populations for Parkinson's disease: lessons from ongoing studies. Mov Disord 2012;27(5):656-665.
    • (2012) Mov Disord , vol.27 , Issue.5 , pp. 656-665
    • Berg, D.1    Marek, K.2    Ross, G.W.3    Poewe, W.4
  • 224
    • 84909642356 scopus 로고    scopus 로고
    • Instrumented Functional Reach Test Differentiates Individuals at High Risk for Parkinsons™ disease from controls
    • Hasmann SE, Berg D, Hobert MA, et al. Instrumented Functional Reach Test Differentiates Individuals at High Risk for Parkinsons™ disease from controls. Front Aging Neurosci 2014;6:286.
    • (2014) Front Aging Neurosci , vol.6 , pp. 286
    • Hasmann, S.E.1    Berg, D.2    Hobert, M.A.3
  • 225
    • 84985914863 scopus 로고    scopus 로고
    • New methods for the assessment of Parkinson's disease (2005 to 2015): a systematic review
    • Sánchez-Ferro Á, Elshehabi M, Godinho C, et al. New methods for the assessment of Parkinson's disease (2005 to 2015): a systematic review. Mov Disord 2016;31(9):1283-1292.
    • (2016) Mov Disord , vol.31 , Issue.9 , pp. 1283-1292
    • Sánchez-Ferro, Á.1    Elshehabi, M.2    Godinho, C.3
  • 226
    • 84862667387 scopus 로고    scopus 로고
    • A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study
    • Postuma RB, Arnulf I, Hogl B, et al. A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study. Mov Disord 2012;27(7):913-916.
    • (2012) Mov Disord , vol.27 , Issue.7 , pp. 913-916
    • Postuma, R.B.1    Arnulf, I.2    Hogl, B.3
  • 227
    • 84928215818 scopus 로고    scopus 로고
    • Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: a multicenter study
    • Postuma RB, Iranzo A, Hogl B, et al. Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: a multicenter study. Ann Neurol 2015;77(5):830-839.
    • (2015) Ann Neurol , vol.77 , Issue.5 , pp. 830-839
    • Postuma, R.B.1    Iranzo, A.2    Hogl, B.3
  • 228
    • 84881553335 scopus 로고    scopus 로고
    • Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series
    • Schenck CH, Boeve BF, Mahowald MW. Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series. Sleep Med 2013;14(8):744-748.
    • (2013) Sleep Med , vol.14 , Issue.8 , pp. 744-748
    • Schenck, C.H.1    Boeve, B.F.2    Mahowald, M.W.3
  • 229
    • 84896267939 scopus 로고    scopus 로고
    • Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients
    • Iranzo A, Fernández-Arcos A, Tolosa E, et al. Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients. PLoS ONE 2014;9(2):e89741.
    • (2014) PLoS ONE , vol.9 , Issue.2
    • Iranzo, A.1    Fernández-Arcos, A.2    Tolosa, E.3
  • 230
    • 27644439093 scopus 로고    scopus 로고
    • Excessive daytime sleepiness and subsequent development of Parkinson disease
    • Abbott RD, Ross GW, White LR, et al. Excessive daytime sleepiness and subsequent development of Parkinson disease. Neurology 2005;65(9):1442-1446.
    • (2005) Neurology , vol.65 , Issue.9 , pp. 1442-1446
    • Abbott, R.D.1    Ross, G.W.2    White, L.R.3
  • 231
    • 79955485357 scopus 로고    scopus 로고
    • Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder
    • Postuma RB, Gagnon J-F, Vendette M, Desjardins C, Montplaisir JY. Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder. Ann Neurol 2011;69(5):811-818.
    • (2011) Ann Neurol , vol.69 , Issue.5 , pp. 811-818
    • Postuma, R.B.1    Gagnon, J.-F.2    Vendette, M.3    Desjardins, C.4    Montplaisir, J.Y.5
  • 232
    • 84944754683 scopus 로고    scopus 로고
    • Clinical implications of delayed orthostatic hypotension
    • Gibbons CH, Freeman R. Clinical implications of delayed orthostatic hypotension. Neurology 2015;85(16):1362-1367.
    • (2015) Neurology , vol.85 , Issue.16 , pp. 1362-1367
    • Gibbons, C.H.1    Freeman, R.2
  • 233
    • 84931094799 scopus 로고    scopus 로고
    • Depression and subsequent risk of Parkinson disease: a nationwide cohort study
    • Gustafsson H, Nordstrom A, Nordstrom P. Depression and subsequent risk of Parkinson disease: a nationwide cohort study. Neurology 2015;84(24):2422-2429.
    • (2015) Neurology , vol.84 , Issue.24 , pp. 2422-2429
    • Gustafsson, H.1    Nordstrom, A.2    Nordstrom, P.3
  • 234
    • 79952941281 scopus 로고    scopus 로고
    • Use of ibuprofen and risk of Parkinson disease
    • Gao X, Chen H, Schwarzschild MA, Ascherio A. Use of ibuprofen and risk of Parkinson disease. Neurology 2011;76(10):863-869.
    • (2011) Neurology , vol.76 , Issue.10 , pp. 863-869
    • Gao, X.1    Chen, H.2    Schwarzschild, M.A.3    Ascherio, A.4
  • 235
    • 84963799520 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers and clinical features in leucine-rich repeat kinase 2 (LRRK2) mutation carriers
    • Vilas D, Shaw LM, Taylor P, et al. Cerebrospinal fluid biomarkers and clinical features in leucine-rich repeat kinase 2 (LRRK2) mutation carriers. Mov Disord 2016;31(6):906-914.
    • (2016) Mov Disord , vol.31 , Issue.6 , pp. 906-914
    • Vilas, D.1    Shaw, L.M.2    Taylor, P.3
  • 236
    • 84922226466 scopus 로고    scopus 로고
    • Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study
    • Jennings D, Siderowf A, Stern M, et al. Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study. Neurology 2014;83(19):1739-1746.
    • (2014) Neurology , vol.83 , Issue.19 , pp. 1739-1746
    • Jennings, D.1    Siderowf, A.2    Stern, M.3
  • 238
    • 84963819506 scopus 로고    scopus 로고
    • Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients
    • Stokholm MG, Danielsen EH, Hamilton-Dutoit SJ, Borghammer P. Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients. Ann Neurol 2016;79(6):940-949.
    • (2016) Ann Neurol , vol.79 , Issue.6 , pp. 940-949
    • Stokholm, M.G.1    Danielsen, E.H.2    Hamilton-Dutoit, S.J.3    Borghammer, P.4
  • 239
    • 84962118986 scopus 로고    scopus 로고
    • Assessment of α-synuclein in submandibular glands of patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study
    • Vilas D, Iranzo A, Tolosa E, et al. Assessment of α-synuclein in submandibular glands of patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study. Lancet Neurol 2016;15(7):708-718.
    • (2016) Lancet Neurol , vol.15 , Issue.7 , pp. 708-718
    • Vilas, D.1    Iranzo, A.2    Tolosa, E.3
  • 240
    • 84941687042 scopus 로고    scopus 로고
    • Did α-synuclein and glucocerebrosidase coevolve? Implications for Parkinson's disease
    • Gruschus JM. Did α-synuclein and glucocerebrosidase coevolve? Implications for Parkinson's disease. PLoS ONE 2015;10(7):e0133863.
    • (2015) PLoS ONE , vol.10 , Issue.7
    • Gruschus, J.M.1
  • 241
    • 0242300619 scopus 로고    scopus 로고
    • Alpha-synuclein locus triplication causes Parkinson's disease
    • Singleton AB. Alpha-synuclein locus triplication causes Parkinson's disease. Science 2003;302(5646):841.
    • (2003) Science , vol.302 , Issue.5646 , pp. 841
    • Singleton, A.B.1
  • 243
    • 84871273435 scopus 로고    scopus 로고
    • Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease
    • Milber JM, Noorigian JV, Morley JF, et al. Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease. Neurology 2012;79(24):2307-2314.
    • (2012) Neurology , vol.79 , Issue.24 , pp. 2307-2314
    • Milber, J.M.1    Noorigian, J.V.2    Morley, J.F.3
  • 244
    • 41349084608 scopus 로고    scopus 로고
    • Patterns and stages of alpha-synucleinopathy: relevance in a population-based cohort
    • Zaccai J, Brayne C, McKeith I, Matthews F, Ince PG. Patterns and stages of alpha-synucleinopathy: relevance in a population-based cohort. Neurology 2008;70(13):1042-1048.
    • (2008) Neurology , vol.70 , Issue.13 , pp. 1042-1048
    • Zaccai, J.1    Brayne, C.2    McKeith, I.3    Matthews, F.4    Ince, P.G.5
  • 245
    • 84971432613 scopus 로고    scopus 로고
    • Lysosomal dysfunction and α-synuclein aggregation in Parkinson's disease: diagnostic links
    • Moors T, Paciotti S, Chiasserini D, et al. Lysosomal dysfunction and α-synuclein aggregation in Parkinson's disease: diagnostic links. Mov Disord 2016;31(6):791-801.
    • (2016) Mov Disord , vol.31 , Issue.6 , pp. 791-801
    • Moors, T.1    Paciotti, S.2    Chiasserini, D.3
  • 246
    • 84958020018 scopus 로고    scopus 로고
    • Autophagy and alpha-synuclein: relevance to Parkinson's disease and related synucleopathies
    • Xilouri M, Brekk OR, Stefanis L. Autophagy and alpha-synuclein: relevance to Parkinson's disease and related synucleopathies. Mov Disord 2016;31(2):178-192.
    • (2016) Mov Disord , vol.31 , Issue.2 , pp. 178-192
    • Xilouri, M.1    Brekk, O.R.2    Stefanis, L.3
  • 249
    • 25144514232 scopus 로고    scopus 로고
    • Somatic mitochondrial DNA mutations in single neurons and glia
    • Cantuti-Castelvetri I, Lin MT, Zheng K, et al. Somatic mitochondrial DNA mutations in single neurons and glia. Neurobiol Aging 2005;26(10):1343-1355.
    • (2005) Neurobiol Aging , vol.26 , Issue.10 , pp. 1343-1355
    • Cantuti-Castelvetri, I.1    Lin, M.T.2    Zheng, K.3
  • 250
    • 85014118305 scopus 로고    scopus 로고
    • Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease
    • Giannoccaro MP, La Morgia C, Rizzo G, Carelli V. Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease. Mov Disord 2017;32(3):346-363.
    • (2017) Mov Disord , vol.32 , Issue.3 , pp. 346-363
    • Giannoccaro, M.P.1    La Morgia, C.2    Rizzo, G.3    Carelli, V.4
  • 251
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW. Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 2008;14(5):504-506.
    • (2008) Nat Med , vol.14 , Issue.5 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 252
    • 42549125030 scopus 로고    scopus 로고
    • The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α-synuclein staging
    • Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RKB. The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α-synuclein staging. Neuropathol Appl Neurobiol 2008;34:284-295.
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 284-295
    • Kalaitzakis, M.E.1    Graeber, M.B.2    Gentleman, S.M.3    Pearce, R.K.B.4
  • 253
    • 84861739631 scopus 로고    scopus 로고
    • Evaluation of the Braak hypothesis: how far can it explain the pathogenesis of Parkinson's disease?
    • Halliday G, McCann H, Shepherd C. Evaluation of the Braak hypothesis: how far can it explain the pathogenesis of Parkinson's disease? Expert Rev Neurother 2012;12:673-686.
    • (2012) Expert Rev Neurother , vol.12 , pp. 673-686
    • Halliday, G.1    McCann, H.2    Shepherd, C.3
  • 254
    • 85010060590 scopus 로고    scopus 로고
    • Selective neuronal vulnerability in Parkinson disease
    • Surmeier DJ, Obeso JA, Halliday GM. Selective neuronal vulnerability in Parkinson disease. Nat Rev Neurosci 2017;18(2):101-113.
    • (2017) Nat Rev Neurosci , vol.18 , Issue.2 , pp. 101-113
    • Surmeier, D.J.1    Obeso, J.A.2    Halliday, G.M.3
  • 255
    • 57649138491 scopus 로고    scopus 로고
    • Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?
    • Kordower JH, Brundin P. Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another? Neuropsychopharmacology 2009;34(1):254.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 254
    • Kordower, J.H.1    Brundin, P.2
  • 256
    • 84876214388 scopus 로고    scopus 로고
    • Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease
    • Surmeier DJ, Schumacker PT. Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease. J Biol Chem 2012;288(15):10736-10741.
    • (2012) J Biol Chem , vol.288 , Issue.15 , pp. 10736-10741
    • Surmeier, D.J.1    Schumacker, P.T.2
  • 257
    • 34247631275 scopus 로고    scopus 로고
    • Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
    • Sulzer D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci 2007;30:244-250.
    • (2007) Trends Neurosci , vol.30 , pp. 244-250
    • Sulzer, D.1
  • 258
    • 65249180086 scopus 로고    scopus 로고
    • Interplay between cytosolic dopamine, calcium, and α-synuclein causes selective death of substantia nigra neurons
    • Mosharov EV, Larsen KE, Kanter E, et al. Interplay between cytosolic dopamine, calcium, and α-synuclein causes selective death of substantia nigra neurons. Neuron 2009;62(2):218-229.
    • (2009) Neuron , vol.62 , Issue.2 , pp. 218-229
    • Mosharov, E.V.1    Larsen, K.E.2    Kanter, E.3
  • 259
    • 47349104402 scopus 로고    scopus 로고
    • Glial reactions in Parkinson's disease
    • McGeer PL, McGeer EG. Glial reactions in Parkinson's disease. Mov Disord 2008;23:474-483.
    • (2008) Mov Disord , vol.23 , pp. 474-483
    • McGeer, P.L.1    McGeer, E.G.2
  • 260
    • 84952845727 scopus 로고    scopus 로고
    • Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease
    • Zucca FA, Segura-Aguilar J, Ferrari E, et al. Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease. Prog Neurobiol 2017;155:96-119.
    • (2017) Prog Neurobiol , vol.155 , pp. 96-119
    • Zucca, F.A.1    Segura-Aguilar, J.2    Ferrari, E.3
  • 261
    • 43249110200 scopus 로고    scopus 로고
    • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
    • Li J-Y, Englund E, Holton JL, et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat Med 2008;14(5):501-503.
    • (2008) Nat Med , vol.14 , Issue.5 , pp. 501-503
    • Li, J.-Y.1    Englund, E.2    Holton, J.L.3
  • 262
    • 84855972240 scopus 로고    scopus 로고
    • Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts
    • Jellinger KA. Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts. Mov Disord 2011;27(1):8-30.
    • (2011) Mov Disord , vol.27 , Issue.1 , pp. 8-30
    • Jellinger, K.A.1
  • 263
    • 69149089854 scopus 로고    scopus 로고
    • Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
    • Desplats P, Lee HJ, Bae EJ, et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A 2009;106(31):13010-13015.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.31 , pp. 13010-13015
    • Desplats, P.1    Lee, H.J.2    Bae, E.J.3
  • 264
    • 72149119358 scopus 로고    scopus 로고
    • Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
    • Luk KC, Song C, O'Brien P, et al. Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells. Proc Natl Acad Sci U S A 2009;106(47):20051-20056.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.47 , pp. 20051-20056
    • Luk, K.C.1    Song, C.2    O'Brien, P.3
  • 265
    • 80053613574 scopus 로고    scopus 로고
    • Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death
    • Volpicelli-Daley LA, Luk KC, Patel TP, et al. Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death. Neuron 2011;72(1):57-71.
    • (2011) Neuron , vol.72 , Issue.1 , pp. 57-71
    • Volpicelli-Daley, L.A.1    Luk, K.C.2    Patel, T.P.3
  • 266
    • 84898007742 scopus 로고    scopus 로고
    • Do prions cause Parkinson disease? The evidence accumulates
    • Olanow CW. Do prions cause Parkinson disease? The evidence accumulates. Ann Neurol 2014;75(3):331-333.
    • (2014) Ann Neurol , vol.75 , Issue.3 , pp. 331-333
    • Olanow, C.W.1
  • 267
    • 84861697687 scopus 로고    scopus 로고
    • Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases
    • Shannon KM, Keshavarzian A, Dodiya HB, Jakate S, Kordower JH. Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases. Mov Disord 2012;27(6):716-719.
    • (2012) Mov Disord , vol.27 , Issue.6 , pp. 716-719
    • Shannon, K.M.1    Keshavarzian, A.2    Dodiya, H.B.3    Jakate, S.4    Kordower, J.H.5
  • 268
    • 84873458538 scopus 로고    scopus 로고
    • Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?
    • Olanow CW, Brundin P. Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder? Mov Disord 2013;28:31-40.
    • (2013) Mov Disord , vol.28 , pp. 31-40
    • Olanow, C.W.1    Brundin, P.2
  • 269
    • 85013040818 scopus 로고    scopus 로고
    • Targeting α-synuclein as a therapy for Parkinson's disease: the battle begins
    • Olanow CW, Kordower JH. Targeting α-synuclein as a therapy for Parkinson's disease: the battle begins. Mov Disord 2017;32(2):203-207.
    • (2017) Mov Disord , vol.32 , Issue.2 , pp. 203-207
    • Olanow, C.W.1    Kordower, J.H.2
  • 270
    • 0033616458 scopus 로고    scopus 로고
    • Science, medicine, and the future: Parkinson's disease
    • Schapira AHV. Science, medicine, and the future: Parkinson's disease. BMJ 1999;318(7179):311-314.
    • (1999) BMJ , vol.318 , Issue.7179 , pp. 311-314
    • Schapira, A.H.V.1
  • 271
    • 0024456653 scopus 로고
    • Effect of deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group. Effect of deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 1989;321(20):1364-1371.
    • (1989) N Engl J Med , vol.321 , Issue.20 , pp. 1364-1371
  • 272
    • 70349456475 scopus 로고    scopus 로고
    • A double-blind, delayed-start trial of rasagiline in Parkinson's disease
    • Olanow CW, Rascol O, Hauser R, et al. A double-blind, delayed-start trial of rasagiline in Parkinson's disease. N Engl J Med 2009;361(13):1268-1278.
    • (2009) N Engl J Med , vol.361 , Issue.13 , pp. 1268-1278
    • Olanow, C.W.1    Rascol, O.2    Hauser, R.3
  • 273
    • 84893841038 scopus 로고    scopus 로고
    • Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial
    • Parkinson Study Group SURE-PD Investigators, Schwarzschild MA, Ascherio A, et al. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol 2014;71(2):141-150.
    • (2014) JAMA Neurol , vol.71 , Issue.2 , pp. 141-150
    • Schwarzschild, M.A.1    Ascherio, A.2
  • 274
    • 84880329276 scopus 로고    scopus 로고
    • Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial
    • Schapira AHV, McDermott MP, Barone P, et al. Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial. Lancet Neurol 2013;12(8):747-755.
    • (2013) Lancet Neurol , vol.12 , Issue.8 , pp. 747-755
    • Schapira, A.H.V.1    McDermott, M.P.2    Barone, P.3
  • 275
    • 84873445906 scopus 로고    scopus 로고
    • Trophic factor gene therapy for Parkinson's disease
    • Kordower JH, Bjorklund A. Trophic factor gene therapy for Parkinson's disease. Mov Disord 2013;28(1):96-109.
    • (2013) Mov Disord , vol.28 , Issue.1 , pp. 96-109
    • Kordower, J.H.1    Bjorklund, A.2
  • 276
    • 84904062975 scopus 로고    scopus 로고
    • Rebuilding the nigrostriatal dopamine pathway: 30 years and counting
    • Collier TJ. Rebuilding the nigrostriatal dopamine pathway: 30 years and counting. Exp Neurol 2014;256:21-24.
    • (2014) Exp Neurol , vol.256 , pp. 21-24
    • Collier, T.J.1
  • 277
    • 0032489683 scopus 로고    scopus 로고
    • Topographical distribution of [125I]-glial cell line-derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection
    • Lapchak PA, Araujo DM, Hilt DC, et al. Topographical distribution of [125I]-glial cell line-derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection. Brain Res 1998;789(1):9-22.
    • (1998) Brain Res , vol.789 , Issue.1 , pp. 9-22
    • Lapchak, P.A.1    Araujo, D.M.2    Hilt, D.C.3
  • 278
    • 0037435511 scopus 로고    scopus 로고
    • Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
    • Nutt JG, Burchiel KJ, Comella CL, et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 2003;60(1):69-73.
    • (2003) Neurology , vol.60 , Issue.1 , pp. 69-73
    • Nutt, J.G.1    Burchiel, K.J.2    Comella, C.L.3
  • 279
    • 0032850453 scopus 로고    scopus 로고
    • Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
    • Kordower JH, Palfi S, Chen E-Y, et al. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 1999;46(3):419-424.
    • (1999) Ann Neurol , vol.46 , Issue.3 , pp. 419-424
    • Kordower, J.H.1    Palfi, S.2    Chen, E.-Y.3
  • 280
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • Kordower JH. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000;290(5492):767-773.
    • (2000) Science , vol.290 , Issue.5492 , pp. 767-773
    • Kordower, J.H.1
  • 281
    • 33644833272 scopus 로고    scopus 로고
    • Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
    • Lang AE, Gill S, Patel NK, et al. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 2007;59(3):459-466.
    • (2007) Ann Neurol , vol.59 , Issue.3 , pp. 459-466
    • Lang, A.E.1    Gill, S.2    Patel, N.K.3
  • 282
    • 84868156476 scopus 로고    scopus 로고
    • Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease
    • Bartus RT, Baumann TL, Brown L, Kruegel BR, Ostrove JM, Herzog CD. Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease. Neurobiol Aging 2013;34(1):35-61.
    • (2013) Neurobiol Aging , vol.34 , Issue.1 , pp. 35-61
    • Bartus, R.T.1    Baumann, T.L.2    Brown, L.3    Kruegel, B.R.4    Ostrove, J.M.5    Herzog, C.D.6
  • 283
    • 41949110690 scopus 로고    scopus 로고
    • Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
    • Marks WJ, Ostrem JL, Verhagen L, et al. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol 2008;7(5):400-408.
    • (2008) Lancet Neurol , vol.7 , Issue.5 , pp. 400-408
    • Marks, W.J.1    Ostrem, J.L.2    Verhagen, L.3
  • 284
    • 84937734362 scopus 로고    scopus 로고
    • Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: a double-blind, randomized, controlled trial
    • Warren OC, Bartus RT, Baumann TL, et al. Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: a double-blind, randomized, controlled trial. Ann Neurol 2015;78(2):248-257.
    • (2015) Ann Neurol , vol.78 , Issue.2 , pp. 248-257
    • Warren, O.C.1    Bartus, R.T.2    Baumann, T.L.3
  • 285
    • 84941068345 scopus 로고    scopus 로고
    • Alpha-synuclein propagation: new insights from animal models
    • Dehay B, Vila M, Bezard E, Brundin P, Kordower JH. Alpha-synuclein propagation: new insights from animal models. Mov Disord 2015;31(2):161-168.
    • (2015) Mov Disord , vol.31 , Issue.2 , pp. 161-168
    • Dehay, B.1    Vila, M.2    Bezard, E.3    Brundin, P.4    Kordower, J.H.5
  • 286
    • 84958037840 scopus 로고    scopus 로고
    • Is alpha-synuclein loss-of-function a contributor to parkinsonian pathology? Evidence from non-human primates
    • Collier TJ, Redmond DE, Steece-Collier K, Lipton JW, Manfredsson FP. Is alpha-synuclein loss-of-function a contributor to parkinsonian pathology? Evidence from non-human primates. Front Neurosci 2016;10:12.
    • (2016) Front Neurosci , vol.10 , pp. 12
    • Collier, T.J.1    Redmond, D.E.2    Steece-Collier, K.3    Lipton, J.W.4    Manfredsson, F.P.5
  • 287
    • 84952700538 scopus 로고    scopus 로고
    • Development of passive Immunotherapies for synucleinopathies
    • Bergström A-L, Kallunki P, Fog K. Development of passive Immunotherapies for synucleinopathies. Mov Disord 2015;31(2):203-213.
    • (2015) Mov Disord , vol.31 , Issue.2 , pp. 203-213
    • Bergström, A.-L.1    Kallunki, P.2    Fog, K.3
  • 289
    • 84903971406 scopus 로고    scopus 로고
    • Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models
    • Games D, Valera E, Spencer B, et al. Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models. J Neurosci 2014;34(28):9441-9454.
    • (2014) J Neurosci , vol.34 , Issue.28 , pp. 9441-9454
    • Games, D.1    Valera, E.2    Spencer, B.3
  • 290
    • 84865202477 scopus 로고    scopus 로고
    • Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation
    • Diogenes MJ, Dias RB, Rombo DM, et al. Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation. J Neurosci 2012;32(34):11750-11762.
    • (2012) J Neurosci , vol.32 , Issue.34 , pp. 11750-11762
    • Diogenes, M.J.1    Dias, R.B.2    Rombo, D.M.3
  • 291
    • 84942038566 scopus 로고    scopus 로고
    • Alpha-synuclein produces early behavioral alterations via striatal cholinergic synaptic dysfunction by interacting with GluN2D N-methyl-D-aspartate receptor subunit
    • Tozzi A, de Iure A, Bagetta V, et al. Alpha-synuclein produces early behavioral alterations via striatal cholinergic synaptic dysfunction by interacting with GluN2D N-methyl-D-aspartate receptor subunit. Biol Psychiatry 2016;79(5):402-414.
    • (2016) Biol Psychiatry , vol.79 , Issue.5 , pp. 402-414
    • Tozzi, A.1    de Iure, A.2    Bagetta, V.3
  • 292
    • 84867036900 scopus 로고    scopus 로고
    • Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains
    • Gegg ME, Burke D, Heales SJR, et al. Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains. Ann Neurol 2012;72(3):455-463.
    • (2012) Ann Neurol , vol.72 , Issue.3 , pp. 455-463
    • Gegg, M.E.1    Burke, D.2    Heales, S.J.R.3
  • 293
    • 84874464883 scopus 로고    scopus 로고
    • Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease
    • Schapira AHV, Gegg ME. Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease. Proc Natl Acad Sci U S A 2013;110(9):3214-3215.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.9 , pp. 3214-3215
    • Schapira, A.H.V.1    Gegg, M.E.2
  • 294
    • 84899819100 scopus 로고    scopus 로고
    • Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells
    • McNeill A, Magalhaes J, Shen C, et al. Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. Brain 2014;137(5):1481-1495.
    • (2014) Brain , vol.137 , Issue.5 , pp. 1481-1495
    • McNeill, A.1    Magalhaes, J.2    Shen, C.3
  • 295
    • 58349122472 scopus 로고    scopus 로고
    • Why have we failed to achieve neuroprotection in Parkinson's disease?
    • Olanow CW, Kieburtz K, Schapira AHV. Why have we failed to achieve neuroprotection in Parkinson's disease? Ann Neurol 2009;64(S2):S101-S110.
    • (2009) Ann Neurol , vol.64 , Issue.S2 , pp. S101-S110
    • Olanow, C.W.1    Kieburtz, K.2    Schapira, A.H.V.3
  • 296
    • 84942421180 scopus 로고    scopus 로고
    • Multitarget disease-modifying therapy in Parkinson's disease?
    • Calabresi P, Di Filippo M. Multitarget disease-modifying therapy in Parkinson's disease? Lancet Neurol 2015;14(10):975-976.
    • (2015) Lancet Neurol , vol.14 , Issue.10 , pp. 975-976
    • Calabresi, P.1    Di Filippo, M.2
  • 297
    • 84906306620 scopus 로고    scopus 로고
    • Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives
    • Schapira AHV, Olanow CW, Greenamyre JT, Bezard E. Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives. Lancet 2014;384(9942):545-555.
    • (2014) Lancet , vol.384 , Issue.9942 , pp. 545-555
    • Schapira, A.H.V.1    Olanow, C.W.2    Greenamyre, J.T.3    Bezard, E.4
  • 298
    • 85028976883 scopus 로고    scopus 로고
    • 200 years since James Parkinson's essay on “The Shaking Palsy” Have we made progress?
    • Chaudhuri KR, Jenner P. 200 years since James Parkinson's essay on “The Shaking Palsy” Have we made progress? Mov Disord 2017;32.
    • (2017) Mov Disord , vol.32
    • Chaudhuri, K.R.1    Jenner, P.2
  • 299
    • 85021997661 scopus 로고    scopus 로고
    • The emerging science of precision medicine and pharmacogenomics for Parkinson's disease
    • Payami H. The emerging science of precision medicine and pharmacogenomics for Parkinson's disease. Mov Disord 2017;32.
    • (2017) Mov Disord , vol.32
    • Payami, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.