Gene therapy approaches to regenerating bone

Advanced Drug Delivery Reviews

Volumn 64, Issue 12, 2012, Pages 1320-1330

  Kimelman Bleich, Nadav ^a   Kallai, Ilan ^a   Lieberman, Jay R ^b   Schwarz, Edward M ^c   Pelled, Gadi ^a,d   Gazit, Dan ^a,d  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Bone regeneration; Gene therapy; Nonviral vectors; Tissue engineering; Viral vectors

Indexed keywords

BONE; FRACTURE; GENES; PROTEINS; RECOMBINANT PROTEINS; TISSUE ENGINEERING; TISSUE REGENERATION;

BONE FORMATION; BONE REGENERATION; CLINICAL SETTINGS; HUMAN BONE MORPHOGENETIC PROTEIN; NONVIRAL VECTORS; RESEARCH RESULTS; VERTEBRAL COMPRESSION; VIRAL VECTORS;

GENE THERAPY;

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 9; CYCLOOXYGENASE 2; LIPOSOME; NAKED DNA; OSTEOGENIC PROTEIN 1; PARATHYROID HORMONE[1-34]; PARVOVIRUS VECTOR; PLASMID DNA; POLYETHYLENEIMINE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RETROVIRUS VECTOR;

BONE DEFECT; BONE DISEASE; BONE MARROW TRANSPLANTATION; BONE REGENERATION; DRUG SAFETY; ELECTROPORATION; EX VIVO GENE TRANSFER; EX VIVO STUDY; EXPERIMENTAL MODEL; GENE THERAPY; HUMAN; IN VIVO STUDY; MEDICAL RESEARCH; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OSSIFICATION; PRIORITY JOURNAL; REVIEW; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BONE AND BONES; BONE DISEASES; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; DISEASE MODELS, ANIMAL; GENETIC THERAPY; GENETIC VECTORS; HUMANS; RECOMBINANT PROTEINS; SPINAL FUSION; TISSUE ENGINEERING;

EID: 85027932729     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.03.007     Document Type: Review

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