Large-scale bicortical skull bone regeneration using ex vivo replication-defective adenoviral-mediated bone morphogenetic protein-2 gene-transferred bone marrow stromal cells and composite biomaterials

Neurosurgery

Volumn 65, Issue 6 SUPPL. 1, 2009, Pages

  Chang, Sophia Chia Ning ^a   Lin, Tsung Min ^a   Chung, Hui Ying ^a   Chen, Philip Kuo Ting ^b   Lin, Feng Huei ^c   Lou, Jeuren ^d   Jeng, Long Bin ^a  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS   (China)

Author keywords

Bone marrow mesenchymal stem cells; E1A deleted adenovirus; Ex vivo gene therapy

Indexed keywords

ADENOVIRUS VECTOR; BIOPOLYMER; BONE MORPHOGENETIC PROTEIN 2; CALCIUM PHOSPHATE CERAMIC; GELATIN; GLUTARALDEHYDE;

ADENOVIRUS 5; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BIOMECHANICS; BIOMEDICAL ENGINEERING; BONE MINERALIZATION; BONE REGENERATION; BONE STRENGTH; CONTROLLED STUDY; EX VIVO GENE TRANSFER; FEMALE; FRACTURE HEALING; HISTOLOGY; MINIPIG; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; SKULL DEFECT; STROMA CELL;

ADENOVIRIDAE; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOPOLYMERS; BONE MARROW TRANSPLANTATION; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; BONE SUBSTITUTES; CALCIUM PHOSPHATES; CELLS, CULTURED; CRANIOTOMY; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLUTARAL; MODELS, ANIMAL; SKULL; STROMAL CELLS; SUS SCROFA; TREATMENT OUTCOME; VIRUS REPLICATION; WOUND HEALING;

EID: 74549193473     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000345947.33730.91     Document Type: Article

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