-
2
-
-
40149086690
-
Nonunions and the potential of stem cells in fracture-healing
-
Tseng SS, Lee MA, Reddi AH. Nonunions and the potential of stem cells in fracture-healing. J Bone Joint Surg Am 2008; 90: 92-98.
-
(2008)
J Bone Joint Surg Am
, vol.90
, pp. 92-98
-
-
Tseng, S.S.1
Lee, M.A.2
Reddi, A.H.3
-
4
-
-
56749173744
-
From 'Gene Therapy' to 'Gene and Cell Therapy': Why?
-
Woo SL. From 'Gene Therapy' to 'Gene and Cell Therapy': why? Mol Ther 2008; 16: 1899-1900.
-
(2008)
Mol Ther
, vol.16
, pp. 1899-1900
-
-
Woo, S.L.1
-
5
-
-
31844454557
-
Direct percutaneous gene delivery to enhance healing of segmental bone defects
-
Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML et al. Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am 2006; 88: 355-365.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 355-365
-
-
Betz, O.B.1
Betz, V.M.2
Nazarian, A.3
Pilapil, C.G.4
Vrahas, M.S.5
Bouxsein, M.L.6
-
6
-
-
34249305403
-
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects
-
Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA et al. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Therapy 2007; 14: 1039-1044.
-
(2007)
Gene Therapy
, vol.14
, pp. 1039-1044
-
-
Betz, O.B.1
Betz, V.M.2
Nazarian, A.3
Egermann, M.4
Gerstenfeld, L.C.5
Einhorn, T.A.6
-
7
-
-
46449095585
-
Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or-6 in equine osteotomy and ostectomy models
-
Ishihara A, Shields KM, Litsky AS, Mattoon JS, Weisbrode SE, Bartlett JS et al. Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or-6 in equine osteotomy and ostectomy models. J Orthop Res 2008; 26: 764-771.
-
(2008)
J Orthop Res
, vol.26
, pp. 764-771
-
-
Ishihara, A.1
Shields, K.M.2
Litsky, A.S.3
Mattoon, J.S.4
Weisbrode, S.E.5
Bartlett, J.S.6
-
8
-
-
34547113749
-
Mesenchymal stem cell-mediated gene delivery of bone morphogenetic protein-2 in an articular fracture model
-
Zachos T, Diggs A, Weisbrode S, Bartlett J, Bertone A. Mesenchymal stem cell-mediated gene delivery of bone morphogenetic protein-2 in an articular fracture model. Mol Ther 2007; 15: 1543-1550.
-
(2007)
Mol Ther
, vol.15
, pp. 1543-1550
-
-
Zachos, T.1
Diggs, A.2
Weisbrode, S.3
Bartlett, J.4
Bertone, A.5
-
9
-
-
41649086624
-
Fluorescence molecular tomography enables in vivo visualization and quantification of nonunion fracture repair induced by genetically engineered mesenchymal stem cells
-
Zilberman Y, Kallai I, Gafni Y, Pelled G, Kossodo S, Yared W et al. Fluorescence molecular tomography enables in vivo visualization and quantification of nonunion fracture repair induced by genetically engineered mesenchymal stem cells. J Orthop Res 2008; 26: 522-530.
-
(2008)
J Orthop Res
, vol.26
, pp. 522-530
-
-
Zilberman, Y.1
Kallai, I.2
Gafni, Y.3
Pelled, G.4
Kossodo, S.5
Yared, W.6
-
10
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
11
-
-
2942550496
-
Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2
-
Hirata K, Tsukazaki T, Kadowaki A, Furukawa K, Shibata Y, Moriishi T et al. Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2. Bone 2000; 32: 502-512.
-
(2000)
Bone
, vol.32
, pp. 502-512
-
-
Hirata, K.1
Tsukazaki, T.2
Kadowaki, A.3
Furukawa, K.4
Shibata, Y.5
Moriishi, T.6
-
12
-
-
33845786565
-
Transplantation of skin fibroblasts expressing BMP-2 contributes to the healing of critical-sized bone defects
-
Hirata K, Mizuno A, Yamaguchi A. Transplantation of skin fibroblasts expressing BMP-2 contributes to the healing of critical-sized bone defects. J Bone Miner Metab 2007; 25: 6-11.
-
(2007)
J Bone Miner Metab
, vol.25
, pp. 6-11
-
-
Hirata, K.1
Mizuno, A.2
Yamaguchi, A.3
-
13
-
-
0034690624
-
Gene therapy-directed osteogenesis: BMP-7-transduced human fibro-blasts form bone in vivo
-
Krebsbach PH, Gu K, Franceschi RT, Rutherford RB. Gene therapy-directed osteogenesis: BMP-7-transduced human fibro-blasts form bone in vivo. Hum Gene Ther 2000; 11: 1201-1210.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1201-1210
-
-
Krebsbach, P.H.1
Gu, K.2
Franceschi, R.T.3
Rutherford, R.B.4
-
14
-
-
0036019364
-
Bone morphogenetic protein-transduced human fibroblasts convert to osteoblasts and form bone in vivo
-
Rutherford RB, Moalli M, Franceschi RT, Wang D, Gu K, Krebsbach PH. Bone morphogenetic protein-transduced human fibroblasts convert to osteoblasts and form bone in vivo. Tissue Eng 2002; 8: 441-452.
-
(2002)
Tissue Eng
, vol.8
, pp. 441-452
-
-
Rutherford, R.B.1
Moalli, M.2
Franceschi, R.T.3
Wang, D.4
Gu, K.5
Krebsbach, P.H.6
-
15
-
-
52049086443
-
Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models
-
Lattanzi W, Parrilla C, Fetoni A, Logroscino G, Straface G, Pecorini G et al. Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models. Gene Therapy 2008; 15: 1330-1343.
-
(2008)
Gene Therapy
, vol.15
, pp. 1330-1343
-
-
Lattanzi, W.1
Parrilla, C.2
Fetoni, A.3
Logroscino, G.4
Straface, G.5
Pecorini, G.6
-
16
-
-
73949150050
-
Dermal fibroblast-mediated BMP2 therapy to accelerate bone healing in an equine osteotomy model
-
Ishihara A, Zekas LJ, Litsky AS, Weisbrode SE, Bertone AL. Dermal fibroblast-mediated BMP2 therapy to accelerate bone healing in an equine osteotomy model. J Orthop Res 2009; 28: 403-411.
-
(2009)
J Orthop Res
, vol.28
, pp. 403-411
-
-
Ishihara, A.1
Zekas, L.J.2
Litsky, A.S.3
Weisbrode, S.E.4
Bertone, A.L.5
-
17
-
-
4844223862
-
Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model
-
Bertone AL, Pittman DD, Bouxsein ML, Li J, Clancy B, Seeherman HJ. Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model. J Orthop Res 2004; 22: 1261-1270.
-
(2004)
J Orthop Res
, vol.22
, pp. 1261-1270
-
-
Bertone, A.L.1
Pittman, D.D.2
Bouxsein, M.L.3
Li, J.4
Clancy, B.5
Seeherman, H.J.6
-
18
-
-
33747586304
-
Effect of BMP-2 gene transfer on bone healing in sheep
-
Egermann M, Lill CA, Griesbeck K, Evans CH, Robbins PD, Schneider E et al. Effect of BMP-2 gene transfer on bone healing in sheep. Gene Therapy 2006; 13: 1290-1299.
-
(2006)
Gene Therapy
, vol.13
, pp. 1290-1299
-
-
Egermann, M.1
Lill, C.A.2
Griesbeck, K.3
Evans, C.H.4
Robbins, P.D.5
Schneider, E.6
-
20
-
-
34249305403
-
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects
-
Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA et al. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Therapy 2007; 14: 1039-1044.
-
(2007)
Gene Therapy
, vol.14
, pp. 1039-1044
-
-
Betz, O.B.1
Betz, V.M.2
Nazarian, A.3
Egermann, M.4
Gerstenfeld, L.C.5
Einhorn, T.A.6
-
21
-
-
49649109923
-
Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo
-
Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N et al. Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J Immunol 2008; 181: 2134-2144.
-
(2008)
J Immunol
, vol.181
, pp. 2134-2144
-
-
Appledorn, D.M.1
Patial, S.2
McBride, A.3
Godbehere, S.4
Van Rooijen, N.5
Parameswaran, N.6
-
22
-
-
65949090277
-
Two key challenges for effective adenovirus-mediated liver gene therapy: Innate immune responses and hepatocyte-specific transduction
-
Descamps D, Benihoud K. Two key challenges for effective adenovirus-mediated liver gene therapy: innate immune responses and hepatocyte-specific transduction. Curr Gene Ther 2009; 9: 115-1127.
-
(2009)
Curr Gene Ther
, vol.9
, pp. 115-1127
-
-
Descamps, D.1
Benihoud, K.2
-
23
-
-
66149123049
-
Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: Indirect complement activation by virions in vivo
-
Tian J, Xu Z, Smith JS, Hofherr SE, Barry MA, Byrnes AP. Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo. J Virol 2009; 83: 5648-5658.
-
(2009)
J Virol
, vol.83
, pp. 5648-5658
-
-
Tian, J.1
Xu, Z.2
Smith, J.S.3
Hofherr, S.E.4
Barry, M.A.5
Byrnes, A.P.6
-
24
-
-
34047221709
-
Immunohistochemical localization of bone morphogenetic proteins (BMPs) 2 4, 6, and 7 during induced heterotopic bone formation
-
McCullough KA, Waits CA, Garimella R, Tague SE, Sipe JB, Anderson HC. Immunohistochemical localization of bone morphogenetic proteins (BMPs) 2, 4, 6, and 7 during induced heterotopic bone formation. J Orthop Res 2007; 25: 465-472.
-
(2007)
J Orthop Res
, vol.25
, pp. 465-472
-
-
McCullough, K.A.1
Waits, C.A.2
Garimella, R.3
Tague, S.E.4
Sipe, J.B.5
Anderson, H.C.6
-
25
-
-
69749121009
-
Engineering three-dimensional cartilage-and bone-like tissues using human dermal fibroblasts and macroporous gelatine micro-carriers
-
e-pub ahead of print
-
Sommar P, Pettersson S, Ness C, Johnson H, Kratz G, Junker JP. Engineering three-dimensional cartilage-and bone-like tissues using human dermal fibroblasts and macroporous gelatine micro-carriers. J Plast Reconstr Aesthet Surg 2009; (e-pub ahead of print).
-
(2009)
J Plast Reconstr Aesthet Surg
-
-
Sommar, P.1
Pettersson, S.2
Ness, C.3
Johnson, H.4
Kratz, G.5
Junker, J.P.6
-
26
-
-
33745501153
-
Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development
-
Okamoto M, Murai J, Yoshikawa H, Tsumaki N. Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development. J Bone Miner Res 2006; 21: 1022-1033.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1022-1033
-
-
Okamoto, M.1
Murai, J.2
Yoshikawa, H.3
Tsumaki, N.4
-
27
-
-
17844398732
-
Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand
-
Itoh K, Udagawa N, Katagiri T, Iemura S, Ueno N, Yasuda H et al. Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand. Endocrinology 2001; 142: 3656-3662.
-
(2001)
Endocrinology
, vol.142
, pp. 3656-3662
-
-
Itoh, K.1
Udagawa, N.2
Katagiri, T.3
Iemura, S.4
Ueno, N.5
Yasuda, H.6
-
28
-
-
0033609409
-
Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2
-
Koide M, Murase Y, Yamato K, Noguchi T, Okahashi N, Nishihara T. Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2. Biochem Biophys Res Commun 1999; 259: 97-102.
-
(1999)
Biochem Biophys Res Commun
, vol.259
, pp. 97-102
-
-
Koide, M.1
Murase, Y.2
Yamato, K.3
Noguchi, T.4
Okahashi, N.5
Nishihara, T.6
-
29
-
-
42749088910
-
Osteoclast-osteoblast communication
-
Matsuo K, Irie N. Osteoclast-osteoblast communication. Arch Biochem Biophys 2008; 473: 201-209.
-
(2008)
Arch Biochem Biophys
, vol.473
, pp. 201-209
-
-
Matsuo, K.1
Irie, N.2
-
30
-
-
0242708809
-
Histomorphometric analysis of the effects of osteocyte density on osteonal morphology and remodeling
-
Metz LN, Martin RB, Turner AS. Histomorphometric analysis of the effects of osteocyte density on osteonal morphology and remodeling. Bone 2003; 33: 753-759.
-
(2003)
Bone
, vol.33
, pp. 753-759
-
-
Metz, L.N.1
Martin, R.B.2
Turner, A.S.3
-
31
-
-
38049042984
-
Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis)
-
McGee ME, Maki AJ, Johnson SE, Nelson OL, Robbins CT, Donahue SW. Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis). Bone 2008; 42: 396-404.
-
(2008)
Bone
, vol.42
, pp. 396-404
-
-
McGee, M.E.1
Maki, A.J.2
Johnson, S.E.3
Nelson, O.L.4
Robbins, C.T.5
Donahue, S.W.6
-
32
-
-
33751509321
-
Structural and remodeling indices in the cancellous bone of the proximal femur across adulthood
-
Tsangari H, Findlay DM, Fazzalari NL. Structural and remodeling indices in the cancellous bone of the proximal femur across adulthood. Bone 2007; 40: 211-217.
-
(2007)
Bone
, vol.40
, pp. 211-217
-
-
Tsangari, H.1
Findlay, D.M.2
Fazzalari, N.L.3
-
33
-
-
36549086149
-
Microcrack frequency and bone remodeling in postmenopausal osteoporotic women on long-term bisphosphonates: A bone biopsy study
-
Chapurlat RD, Arlot M, Burt-Pichat B, Chavassieux P, Roux JP, Portero-Muzy N et al. Microcrack frequency and bone remodeling in postmenopausal osteoporotic women on long-term bisphosphonates: a bone biopsy study. J Bone Miner Res 2007; 22: 1502-1509.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 1502-1509
-
-
Chapurlat, R.D.1
Arlot, M.2
Burt-Pichat, B.3
Chavassieux, P.4
Roux, J.P.5
Portero-Muzy, N.6
-
34
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
35
-
-
33750475626
-
Quantitative real-time RT-PCR data analysis: Current concepts and the novel 'gene expression's CT difference' formula
-
Schefe JH, Lehmann KE, Buschmann IR, Unger T, Funke-Kaiser H. Quantitative real-time RT-PCR data analysis: current concepts and the novel 'gene expression's CT difference' formula. J Mol Med 2006; 84: 901-910.
-
(2006)
J Mol Med
, vol.84
, pp. 901-910
-
-
Schefe, J.H.1
Lehmann, K.E.2
Buschmann, I.R.3
Unger, T.4
Funke-Kaiser, H.5
|