-
1
-
-
44249120315
-
Effect of gene therapy on visual function in Leber's congenital amaurosis
-
DOI 10.1056/NEJMoa0802268
-
Bainbridge JW, Smith AJ, Barker SS, et al. Effect of gene therapy on visual function in Leber's congenital amaurosis. N Engl J Med 2008;358:2231-9. (Pubitemid 351724452)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.21
, pp. 2231-2239
-
-
Bainbridge, J.W.B.1
Smith, A.J.2
Barker, S.S.3
Robbie, S.4
Henderson, R.5
Balaggan, K.6
Viswanathan, A.7
Holder, G.E.8
Stockman, A.9
Tyler, N.10
Petersen-Jones, S.11
Bhattacharya, S.S.12
Thrasher, A.J.13
Fitzke, F.W.14
Carter, B.J.15
Rubin, G.S.16
Moore, A.T.17
Ali, R.R.18
-
2
-
-
0032618428
-
A gene therapy approach to accelerating bone healing. Evaluation of gene expression in a New Zealand white rabbit model
-
Baltzer AW, Lattermann C, Whalen JD, et al. A gene therapy approach to accelerating bone healing. Evaluation of gene expression in a New Zealand white rabbit model. Knee Surg Sports Traumatol Arthrosc 1999;7:197-202.
-
(1999)
Knee Surg Sports Traumatol Arthrosc
, vol.7
, pp. 197-202
-
-
Baltzer, A.W.1
Lattermann, C.2
Whalen, J.D.3
-
3
-
-
85047699915
-
Genetic enhancement of fracture repair: Healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene
-
DOI 10.1038/sj/gt/3301166
-
Baltzer AW, Lattermann C, Whalen JD, et al. Genetic enhancement of fracture repair: healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene. Gene Ther 2000;7:734-9. (Pubitemid 30255754)
-
(2000)
Gene Therapy
, vol.7
, Issue.9
, pp. 734-739
-
-
Baltzer, A.W.A.1
Lattermann, C.2
Whalen, J.D.3
Wooley, P.4
Weiss, K.5
Grimm, M.6
Ghivizzani, S.C.7
Robbins, P.D.8
Evans, C.H.9
-
4
-
-
34249305403
-
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects
-
DOI 10.1038/sj.gt.3302956, PII 3302956
-
Betz OB, Betz VM, Nazarian A, et al. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther 2007;14:1039-44. (Pubitemid 46965273)
-
(2007)
Gene Therapy
, vol.14
, Issue.13
, pp. 1039-1044
-
-
Betz, O.B.1
Betz, V.M.2
Nazarian, A.3
Egermann, M.4
Gerstenfeld, L.C.5
Einhorn, T.A.6
Vrahas, M.S.7
Bouxsein, M.L.8
Evans, C.H.9
-
5
-
-
31844454557
-
Direct percutaneous gene delivery to enhance healing of segmental bone defects
-
DOI 10.2106/JBJS.E.00464
-
Betz OB, Betz VM, Nazarian A, et al. Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am 2006;88:355-65. (Pubitemid 43185138)
-
(2006)
Journal of Bone and Joint Surgery - Series A
, vol.88
, Issue.2
, pp. 355-365
-
-
Betz, O.B.1
Betz, V.M.2
Nazarian, A.3
Pilapil, C.G.4
Vrahas, M.S.5
Bouxsein, M.L.6
Gerstenfeld, L.C.7
Einhorn, T.A.8
Evans, C.H.9
-
6
-
-
35348876799
-
Healing of segmental bone defects by direct percutaneousgenedelivery: Effectofvectordose
-
Betz VM, Betz OB, Glatt V, et al. Healing of segmental bone defects by direct percutaneousgenedelivery: effectofvectordose.HumGeneTher2007;18:907-15.
-
(2007)
HumGeneTher
, vol.18
, pp. 907-915
-
-
Betz, V.M.1
Betz, O.B.2
Glatt, V.3
-
7
-
-
0033021062
-
Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
-
DOI 10.1038/10473
-
Bonadio J, Smiley E, Patil P, Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat Med 1999;5:753-9. (Pubitemid 29318608)
-
(1999)
Nature Medicine
, vol.5
, Issue.7
, pp. 753-759
-
-
Bonadio, J.1
Smiley, E.2
Patil, P.3
Goldstein, S.4
-
8
-
-
0032941836
-
Gene-Enhanced Tissue Engineering: Applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene
-
Breitbart AS, Grande DA, Mason JM, et al. Gene-enhanced tissue engineering: applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene. Ann Plast Surg 1999;42:488-95. (Pubitemid 29218313)
-
(1999)
Annals of Plastic Surgery
, vol.42
, Issue.5
, pp. 488-495
-
-
Breitbart, A.S.1
Grande, D.A.2
Mason, J.M.3
Barcia, M.4
James, T.5
Grant, R.T.6
-
9
-
-
72449169616
-
Alipogene tiparvovec, an adeno-associated virus encoding the Ser(447)X variant of the human lipoprotein lipase gene for the treatment of patients with lipoprotein lipase deficiency
-
Burnett JR, Hooper AJ. Alipogene tiparvovec, an adeno-associated virus encoding the Ser(447)X variant of the human lipoprotein lipase gene for the treatment of patients with lipoprotein lipase deficiency. Curr Opin Mol Ther 2009;11:681-91.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 681-691
-
-
Burnett, J.R.1
Hooper, A.J.2
-
11
-
-
66149096522
-
Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use
-
Chang PC, Cirelli JA, Jin Q, et al. Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use. Hum Gene Ther 2009;20:486-96.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 486-496
-
-
Chang, P.C.1
Cirelli, J.A.2
Jin, Q.3
-
12
-
-
74549193473
-
Large-scale bicortical skull bone regeneration using ex vivo replication-defective adenoviral-mediated bone morphogenetic protein-2 gene-transferred bone marrow stromal cells and composite biomaterials
-
discussion 3
-
Chang SC, Lin TM, Chung HY, et al. Large-scale bicortical skull bone regeneration using ex vivo replication-defective adenoviral-mediated bone morphogenetic protein-2 gene-transferred bone marrow stromal cells and composite biomaterials. Neurosurgery 2009;65(75-81). [discussion 3].
-
(2009)
Neurosurgery
, vol.65
, Issue.75-81
-
-
Chang, S.C.1
Lin, T.M.2
Chung, H.Y.3
-
13
-
-
70349625785
-
Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice
-
Chen L, Tredget EE, Liu C, Wu Y. Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice. PLoS One 2009;4:e7119.
-
(2009)
PLoS One
, vol.4
-
-
Chen, L.1
Tredget, E.E.2
Liu, C.3
Wu, Y.4
-
14
-
-
35348855682
-
VEGF: An essential mediator of both angiogenesis and endochondral ossification
-
Dai J, Rabie AB. VEGF: an essential mediator of both angiogenesis and endochondral ossification. J Dent Res 2007;86:937-50.
-
(2007)
J Dent Res
, vol.86
, pp. 937-950
-
-
Dai, J.1
Rabie, A.B.2
-
15
-
-
27144471318
-
Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone
-
DOI 10.1007/s00223-004-0095-z
-
Dai KR, Xu XL, Tang TT, et al. Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone. Calcif Tissue Int 2005;77:55-61. (Pubitemid 41504173)
-
(2005)
Calcified Tissue International
, vol.77
, Issue.1
, pp. 55-61
-
-
Dai, K.R.1
Xu, X.L.2
Tang, T.T.3
Zhu, Z.A.4
Yu, C.F.5
Lou, J.R.6
Zhang, X.L.7
-
17
-
-
33646946177
-
Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep
-
DOI 10.1089/hum.2006.17.507
-
Egermann M, Baltzer AW, Adamaszek S, et al. Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep. Hum Gene Ther 2006;17:507-17. (Pubitemid 43794490)
-
(2006)
Human Gene Therapy
, vol.17
, Issue.5
, pp. 507-517
-
-
Egermann, M.1
Baltzer, A.W.2
Adamaszek, S.3
Evans, C.4
Robbins, P.5
Schneider, E.6
Lill, C.A.7
-
18
-
-
33747586304
-
Effect of BMP-2 gene transfer on bone healing in sheep
-
DOI 10.1038/sj.gt.3302785, PII 3302785
-
Egermann M, Lill CA, Griesbeck K, et al. Effect of BMP-2 gene transfer on bone healing in sheep. Gene Ther 2006;13:1290-9. (Pubitemid 44264083)
-
(2006)
Gene Therapy
, vol.13
, Issue.17
, pp. 1290-1299
-
-
Egermann, M.1
Lill, C.A.2
Griesbeck, K.3
Evans, C.H.4
Robbins, P.D.5
Schneider, E.6
Baltzer, A.W.7
-
19
-
-
70350673594
-
Progenitor and stem cells for bone and cartilage regeneration
-
El Tamer MK, Reis RL. Progenitor and stem cells for bone and cartilage regeneration. J Tissue Eng Regen Med 2009;3:327-37.
-
(2009)
J Tissue Eng Regen Med
, vol.3
, pp. 327-337
-
-
El Tamer, M.K.1
Reis, R.L.2
-
20
-
-
77955485475
-
Gene therapy for bone healing
-
10.1017/S1462399410001493
-
Evans CH. Gene therapy for bone healing. Expert Rev Mol Med 2010;12:e18. 10.1017/S1462399410001493.
-
(2010)
Expert Rev Mol Med
, vol.12
-
-
Evans, C.H.1
-
22
-
-
84875951313
-
Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage
-
Evans CH, Liu FJ, Glatt V, et al. Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. Eur Cell Mater 2009;18:96-111.
-
(2009)
Eur Cell Mater
, vol.18
, pp. 96-111
-
-
Evans, C.H.1
Liu, F.J.2
Glatt, V.3
-
23
-
-
34548085955
-
Facilitated endogenous repair: Making tissue engineering simple, practical, and economical
-
DOI 10.1089/ten.2006.0302
-
Evans CH, Palmer GD, Pascher A, et al. Facilitated endogenous repair: making tissue engineering simple, practical, and economical. Tissue Eng 2007;13: 1987-93. (Pubitemid 47293994)
-
(2007)
Tissue Engineering
, vol.13
, Issue.8
, pp. 1987-1993
-
-
Evans, C.H.1
Palmer, G.D.2
Pascher, A.3
Porter, R.4
Kwong, F.N.5
Gouze, E.6
Gouze, J.-N.7
Liu, F.8
Steinert, A.9
Betz, O.10
Betz, V.11
Vrahas, M.12
Ghivizzani, S.C.13
-
24
-
-
0029994334
-
Stimulation of new bone formation by direct transfer of osteogenic plasmid genes
-
DOI 10.1073/pnas.93.12.5753
-
Fang J, Zhu YY, Smiley E, et al. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc Natl Acad Sci U S A 1996;93:5753-8. (Pubitemid 26190752)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.12
, pp. 5753-5758
-
-
Fang, J.1
Zhu, Y.-Y.2
Smiley, E.3
Bonadio, J.4
Rouleau, J.P.5
Goldstein, S.A.6
Mccauley, L.K.7
Davidson, B.L.8
Roessler, B.J.9
-
25
-
-
0033084785
-
Engineered Pluripotent Mesenchymal Cells Integrate and Differentiate in Regenerating Bone: A Novel Cell-Mediated Gene Therapy
-
Gazit D, Turgeman G, Kelley P, et al. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. J Gene Med 1999;1:121-33. (Pubitemid 129631069)
-
(1999)
Journal of Gene Medicine
, vol.1
, Issue.2
, pp. 121-133
-
-
Gazit, D.1
Turgeman, G.2
Kelley, P.3
Wang, E.4
Jalenak, M.5
Zilberman, Y.6
Moutsatsos, I.7
-
26
-
-
33749540127
-
Bone regeneration with active angiogenesis by basic fibroblast growth factor gene transfected mesenchymal stem cells seeded on porous beta-TCP ceramic scaffolds
-
DOI 10.1088/1748-6041/1/3/001, PII S1748604106203784, 001
-
Guo X, Zheng Q, Kulbatski I, et al. Bone regeneration with active angiogenesis by basic fibroblast growth factor gene transfected mesenchymal stem cells seeded on porous beta-TCP ceramic scaffolds. Biomed Mater 2006;1:93-9. (Pubitemid 44529332)
-
(2006)
Biomedical Materials
, vol.1
, Issue.3
, pp. 93-99
-
-
Guo, X.1
Zheng, Q.2
Kulbatski, I.3
Yuan, Q.4
Yang, S.5
Shao, Z.6
Wang, H.7
Xiao, B.8
Pan, Z.9
Tang, S.10
-
27
-
-
77954833516
-
Efficacy of gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, Hauer J, Lim A, et al. Efficacy of gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 2010;363:355-64.
-
(2010)
N Engl J Med
, vol.363
, pp. 355-364
-
-
Hacein-Bey-Abina, S.1
Hauer, J.2
Lim, A.3
-
28
-
-
77953251302
-
Viral vectors for gene transfer: Current status of gene therapeutics
-
Heilbronn R, Weger S. Viral vectors for gene transfer: current status of gene therapeutics. Handb Exp Pharmacol 2010:143-70.
-
(2010)
Handb Exp Pharmacol
, pp. 143-170
-
-
Heilbronn, R.1
Weger, S.2
-
29
-
-
0034127731
-
Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent
-
Helm GA, Alden TD, Beres EJ, et al. Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent. J Neurosurg 2000;92:191-6. (Pubitemid 30207415)
-
(2000)
Journal of Neurosurgery
, vol.92
, Issue.2 SUPPL.
, pp. 191-196
-
-
Helm, G.A.1
Alden, T.D.2
Beres, E.J.3
Hudson, S.B.4
Das, S.5
Engh, J.A.6
Pittman, D.D.7
Kerns, K.M.8
Kallmes, D.F.9
-
30
-
-
57949102222
-
How do mesenchymal stromal cells exert their therapeutic benefit?
-
Horwitz EM, Dominici M. How do mesenchymal stromal cells exert their therapeutic benefit? Cytotherapy 2008;10:771-4.
-
(2008)
Cytotherapy
, vol.10
, pp. 771-774
-
-
Horwitz, E.M.1
Dominici, M.2
-
31
-
-
46449095585
-
Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or -6 in equine osteotomy and ostectomy models
-
Ishihara A, Shields KM, Litsky AS, et al. Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or -6 in equine osteotomy and ostectomy models. J Orthop Res 2008;26:764-71.
-
(2008)
J Orthop Res
, vol.26
, pp. 764-771
-
-
Ishihara, A.1
Shields, K.M.2
Litsky, A.S.3
-
32
-
-
73949150050
-
Dermal fibroblast-mediated BMP2 therapy to accelerate bone healing in an equine osteotomy model
-
Ishihara A, Zekas LJ, Litsky AS, et al. Dermal fibroblast-mediated BMP2 therapy to accelerate bone healing in an equine osteotomy model. J Orthop Res 2010;28:403-11.
-
(2010)
J Orthop Res
, vol.28
, pp. 403-411
-
-
Ishihara, A.1
Zekas, L.J.2
Litsky, A.S.3
-
33
-
-
20144387650
-
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
-
DOI 10.1038/nm1190
-
Ito H, Koefoed M, Tiyapatanaputi P, et al. Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med 2005;11:291-7. (Pubitemid 40460557)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 291-297
-
-
Ito, H.1
Koefoed, M.2
Tiyapatanaputi, P.3
Gromov, K.4
Goater, J.J.5
Carmouche, J.6
Zhang, X.7
Rubery, P.T.8
Rabinowitz, J.9
Samulski, R.J.10
Nakamura, T.11
Soballe, K.12
O'Keefe, R.J.13
Boyce, B.F.14
Schwarz, E.M.15
-
34
-
-
0041375517
-
Coxsackievirus and adenovirus receptor (CAR)-positive immature osteoblasts as targets of adenovirus-mediated gene transfer for fracture healing
-
DOI 10.1038/sj.gt.3302060
-
Ito T, Tokunaga K, Maruyama H, et al. Coxsackievirus and adenovirus receptor (CAR)-positive immature osteoblasts as targets of adenovirus-mediated gene transfer for fracture healing. Gene Ther 2003;10:1623-8. (Pubitemid 37063269)
-
(2003)
Gene Therapy
, vol.10
, Issue.18
, pp. 1623-1628
-
-
Ito, T.1
Tokunaga, K.2
Maruyama, H.3
Kawashima, H.4
Kitahara, H.5
Horikoshi, T.6
Ogose, A.7
Hotta, Y.8
Kuwano, R.9
Katagiri, H.10
Endo, N.11
-
35
-
-
22644443111
-
Biological effects of rAAV-caAlk2 coating on structural allograft healing
-
DOI 10.1016/j.ymthe.2005.02.026, PII S1525001605001097
-
Koefoed M, Ito H, Gromov K, et al. Biological effects of rAAV-caAlk2 coating on structural allograft healing. Mol Ther 2005;12:212-8. (Pubitemid 41025090)
-
(2005)
Molecular Therapy
, vol.12
, Issue.2
, pp. 212-218
-
-
Koefoed, M.1
Ito, H.2
Gromov, K.3
Reynolds, D.G.4
Awad, H.A.5
Rubery, P.T.6
Ulrich-Vinther, M.7
Soballe, K.8
Guldberg, R.E.9
Lin, A.S.P.10
O'Keefe, R.J.11
Zhang, X.12
Schwarz, E.M.13
-
36
-
-
52649100956
-
Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration
-
Koh JT, Zhao Z, Wang Z, et al. Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration. J Dent Res 2008;87:845-9.
-
(2008)
J Dent Res
, vol.87
, pp. 845-849
-
-
Koh, J.T.1
Zhao, Z.2
Wang, Z.3
-
37
-
-
56449123273
-
Recent developments in the biology of fracture repair
-
Kwong FN, Harris MB. Recent developments in the biology of fracture repair. J Am Acad Orthop Surg 2008;16:619-25.
-
(2008)
J Am Acad Orthop Surg
, vol.16
, pp. 619-625
-
-
Kwong, F.N.1
Harris, M.B.2
-
38
-
-
45749094563
-
Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells
-
Kwong FN, Richardson SM, Evans CH. Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells. Arthritis Res Ther 2008;10:R65.
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Kwong, F.N.1
Richardson, S.M.2
Evans, C.H.3
-
39
-
-
52049086443
-
Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models
-
Lattanzi W, Parrilla C, Fetoni A, et al. Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models. Gene Ther 2008;15:1330-43.
-
(2008)
Gene Ther
, vol.15
, pp. 1330-1343
-
-
Lattanzi, W.1
Parrilla, C.2
Fetoni, A.3
-
40
-
-
0034917376
-
Effect of bone morphogenetic protein-2-expressing muscle-derived cells on healing of critical-sized bone defects in mice
-
Lee JY, Musgrave D, Pelinkovic D, et al. Effect of bone morphogenetic protein-2- expressing muscle-derived cells on healing of critical-sized bone defects in mice. J Bone Joint Surg Am 2001;83-A:1032-9. (Pubitemid 32662105)
-
(2001)
Journal of Bone and Joint Surgery - Series A
, vol.83
, Issue.7
, pp. 1032-1039
-
-
Joon, Y.L.1
Musgrave, D.2
Pelinkovic, D.3
Fukushima, K.4
Cummins, J.5
Usas, A.6
Robbins, P.7
Fu, F.H.8
Huard, J.9
-
41
-
-
67651163639
-
Treatment of rabbit femoral defect by firearm with BMP-4 gene combined with TGF-beta1
-
Li BC, Zhang JJ, Xu C, et al. Treatment of rabbit femoral defect by firearm with BMP-4 gene combined with TGF-beta1. J Trauma 2009;66:450-6.
-
(2009)
J Trauma
, vol.66
, pp. 450-456
-
-
Li, B.C.1
Zhang, J.J.2
Xu, C.3
-
42
-
-
0032866489
-
The effect of regional gene therapy with bone morphogenetic protein-2- producing bone-marrow cells on the repair of segmental femoral defects in rats
-
Lieberman JR, Daluiski A, Stevenson S, et al. The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. J Bone Joint Surg Am 1999;81:905-17. (Pubitemid 29354999)
-
(1999)
Journal of Bone and Joint Surgery - Series A
, vol.81
, Issue.7
, pp. 905-917
-
-
Lieberman, J.R.1
Daluiski, A.2
Stevenson, S.3
Wu, L.4
McAllister, P.5
Lee, Y.P.6
Kabo, J.M.7
Finerman, G.A.M.8
Berk, A.J.9
Witte, O.N.10
-
43
-
-
0032077625
-
Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents
-
DOI 10.1002/jor.1100160309
-
Lieberman JR, Le LQ, Wu L, et al. Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents. J Orthop Res 1998;16:330-9. (Pubitemid 28337629)
-
(1998)
Journal of Orthopaedic Research
, vol.16
, Issue.3
, pp. 330-339
-
-
Lieberman, J.R.1
Le, L.Q.2
Wu, L.3
Finerman, G.A.M.4
Berk, A.5
Witte, O.N.6
Stevenson, S.7
-
44
-
-
33845786651
-
The osteoinductive properties of Nell-1 in a rat spinal fusion model
-
DOI 10.1016/j.spinee.2006.04.020, PII S1529943006002269
-
Lu SS, Zhang X, Soo C, et al. The osteoinductive properties of Nell-1 in a rat spinal fusion model. Spine J 2007;7:50-60. (Pubitemid 46002542)
-
(2007)
Spine Journal
, vol.7
, Issue.1
, pp. 50-60
-
-
Lu, S.S.1
Zhang, X.2
Soo, C.3
Hsu, T.4
Napoli, A.5
Aghaloo, T.6
Wu, B.M.7
Tsou, P.8
Ting, K.9
Wang, J.C.10
-
45
-
-
44249085878
-
Safety and efficacy of gene transfer for Leber's congenital amaurosis
-
DOI 10.1056/NEJMoa0802315
-
Maguire AM, Simonelli F, Pierce EA, et al. Safety and efficacy of gene transfer for Leber's congenital amaurosis. N Engl J Med 2008;358:2240-8. (Pubitemid 351724453)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.21
, pp. 2240-2248
-
-
Maguire, A.M.1
Simonelli, F.2
Pierce, E.A.3
Pugh Jr., E.N.4
Mingozzi, F.5
Bennicelli, J.6
Banfi, S.7
Marshall, K.A.8
Testa, F.9
Surace, E.M.10
Rossi, S.11
Lyubarsky, A.12
Arruda, V.R.13
Konkle, B.14
Stone, E.15
Sun, J.16
Jacobs, J.17
Dell'Osso, L.18
Hertle, R.19
Ma, J.-X.20
Redmond, T.M.21
Zhu, X.22
Hauck, B.23
Zelenaia, O.24
Shindler, K.S.25
Maguire, M.G.26
Wright, J.F.27
Volpe, N.J.28
McDonnell, J.W.29
Auricchio, A.30
High, K.A.31
Bennett, J.32
more..
-
46
-
-
52049104885
-
The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats
-
Miyazaki M, Sugiyama O, Tow B, et al. The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats. J Spinal Disord Tech 2008;21:372-9.
-
(2008)
J Spinal Disord Tech
, vol.21
, pp. 372-379
-
-
Miyazaki, M.1
Sugiyama, O.2
Tow, B.3
-
47
-
-
46749155471
-
Comparison of lentiviral and adenoviral gene therapy for spinal fusion in rats
-
Miyazaki M, Sugiyama O, Zou J, et al. Comparison of lentiviral and adenoviral gene therapy for spinal fusion in rats. Spine (Philadelphia PA 1976) 2008;33:1410-7.
-
(2008)
Spine (Philadelphia PA 1976)
, vol.33
, pp. 1410-1417
-
-
Miyazaki, M.1
Sugiyama, O.2
Zou, J.3
-
49
-
-
77649137075
-
Autologous bone graft: Properties and techniques
-
Pape HC, Evans A, Kobbe P. Autologous bone graft: properties and techniques. J Orthop Trauma; 24 Suppl. 1 S36-40.
-
J Orthop Trauma
, vol.24
, Issue.SUPPL. 1
-
-
Pape, H.C.1
Evans, A.2
Kobbe, P.3
-
50
-
-
10744229809
-
Gene delivery to cartilage defects using coagulated bone marrow aspirate
-
DOI 10.1038/sj.gt.3302155
-
Pascher A, Palmer GD, Steinert A, et al. Gene delivery to cartilage defects using coagulated bone marrow aspirate. Gene Ther 2004;11:133-41. (Pubitemid 38159685)
-
(2004)
Gene Therapy
, vol.11
, Issue.2
, pp. 133-141
-
-
Pascher, A.1
Palmer, G.D.2
Steinert, A.3
Oligino, T.4
Gouze, E.5
Gouze, J.-N.6
Betz, O.7
Spector, M.8
Robbins, P.D.9
Evans, C.H.10
Ghivizzani, S.C.11
-
51
-
-
73449101112
-
Recent trends in non-viral vector-mediated gene delivery
-
Pathak A, Patnaik S, Gupta KC. Recent trends in non-viral vector-mediated gene delivery. Biotechnol J 2009;4:1559-72.
-
(2009)
Biotechnol J
, vol.4
, pp. 1559-1572
-
-
Pathak, A.1
Patnaik, S.2
Gupta, K.C.3
-
52
-
-
76749092694
-
Direct gene therapy for bone regeneration: Gene delivery, animal models, and outcome measures
-
Pelled G, Ben-Arav, A, Hock, C, et al. Direct gene therapy for bone regeneration: gene delivery, animal models, and outcome measures. Tissue Eng Part B Rev 16, 13-20.
-
Tissue Eng Part B Rev
, vol.16
, pp. 13-20
-
-
Pelled, G.1
Ben-Arav, A.2
Hock, C.3
-
53
-
-
0036738338
-
Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
-
Peng H, Wright V, Usas A, et al. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 2002;110:751-9.
-
(2002)
J Clin Invest
, vol.110
, pp. 751-759
-
-
Peng, H.1
Wright, V.2
Usas, A.3
-
54
-
-
13444268948
-
Genetically modified human derived bone marrow cells for posterolateral lumbar spine fusion in athymic rats: Beyond conventional autologous bone grafting
-
discussion 9-90
-
Peterson B, Iglesias R, Zhang J, et al. Genetically modified human derived bone marrow cells for posterolateral lumbar spine fusion in athymic rats: beyond conventional autologous bone grafting. Spine (Philadelphia PA 1976) 2005;30:283-9. [discussion 9-90].
-
(2005)
Spine (Philadelphia PA 1976)
, vol.30
, pp. 283-289
-
-
Peterson, B.1
Iglesias, R.2
Zhang, J.3
-
55
-
-
17144412168
-
Healing of critically sized femoral defects, using genetically modified mesenchymal stem cells from human adipose tissue
-
DOI 10.1089/ten.2005.11.120
-
Peterson B, Zhang J, Iglesias R, et al. Healing of critically sized femoral defects, using genetically modified mesenchymal stem cells from human adipose tissue. Tissue Eng 2005;11:120-9. (Pubitemid 40515180)
-
(2005)
Tissue Engineering
, vol.11
, Issue.1-2
, pp. 120-129
-
-
Peterson, B.1
Zhang, J.2
Iglesias, R.3
Kabo, M.4
Hedrick, M.5
Benhaim, P.6
Lieberman, J.R.7
-
56
-
-
0142124749
-
In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4
-
Rundle CH, Miyakoshi N, Kasukawa Y, et al. In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4. Bone 2003;32:591-601.
-
(2003)
Bone
, vol.32
, pp. 591-601
-
-
Rundle, C.H.1
Miyakoshi, N.2
Kasukawa, Y.3
-
57
-
-
40549106124
-
Retroviral-based gene therapy with cyclooxygenase-2 promotes the union of bony callus tissues and accelerates fracture healing in the rat
-
Rundle CH, Strong DD, Chen ST, et al. Retroviral-based gene therapy with cyclooxygenase-2 promotes the union of bony callus tissues and accelerates fracture healing in the rat. J Gene Med 2008;10:229-41.
-
(2008)
J Gene Med
, vol.10
, pp. 229-241
-
-
Rundle, C.H.1
Strong, D.D.2
Chen, S.T.3
-
58
-
-
77952199886
-
Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering
-
Scotti C, Tonnarelli B, Papadimitropoulos A, et al. Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc Natl Acad Sci U S A 2010;107:7251-6.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7251-7256
-
-
Scotti, C.1
Tonnarelli, B.2
Papadimitropoulos, A.3
-
59
-
-
0036771653
-
Systematically administered mesenchymal stromal cells transduced with insulin-like growth factor-I localize to a fracture site and potentiate healing
-
DOI 10.1097/00005131-200210000-00007
-
Shen FH, Visger JM, Balian G, et al. Systemically administered mesenchymal stromal cells transduced with insulin-like growth factor-I localize to a fracture site and potentiate healing. J Orthop Trauma 2002;16:651-9. (Pubitemid 35214856)
-
(2002)
Journal of Orthopaedic Trauma
, vol.16
, Issue.9
, pp. 651-659
-
-
Shen, F.H.1
Visger, J.M.2
Balian, G.3
Hurwitz, S.R.4
Diduch, D.R.5
-
60
-
-
75949130376
-
Ex vivo bone morphogenetic protein-2 gene delivery using gingival fibroblasts promotes bone regeneration in rats
-
Shin JH, Kim KH, Kim SH, et al. Ex vivo bone morphogenetic protein-2 gene delivery using gingival fibroblasts promotes bone regeneration in rats. J Clin Periodontol 2010;37:305-11.
-
(2010)
J Clin Periodontol
, vol.37
, pp. 305-311
-
-
Shin, J.H.1
Kim, K.H.2
Kim, S.H.3
-
61
-
-
33646348736
-
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore EM, Xu M, Feldman GJ, et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet 2006;38:525-7.
-
(2006)
Nat Genet
, vol.38
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
-
62
-
-
3142731900
-
Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: Application of biomaterial to mask the host immune response
-
DOI 10.1089/1043034041361208
-
Sonobe J, Okubo Y, Kaihara S, et al. Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response. Hum Gene Ther 2004;15:659-68. (Pubitemid 38925218)
-
(2004)
Human Gene Therapy
, vol.15
, Issue.7
, pp. 659-668
-
-
Sonobe, J.1
Okubo, Y.2
Kaihara, S.3
Miyatake, S.-I.4
Bessho, K.5
-
63
-
-
52649114788
-
LMP-1 retroviral gene therapy influences osteoblast differentiation and fracture repair: A preliminary study
-
Strohbach CA, Rundle CH, Wergedal JE, et al. LMP-1 retroviral gene therapy influences osteoblast differentiation and fracture repair: a preliminary study. Calcif Tissue Int 2008;83:202-11.
-
(2008)
Calcif Tissue Int
, vol.83
, pp. 202-211
-
-
Strohbach, C.A.1
Rundle, C.H.2
Wergedal, J.E.3
-
64
-
-
67649433434
-
Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine
-
Sundelacruz S, Kaplan DL. Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine. Semin Cell Dev Biol 2009;20:646-55.
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 646-655
-
-
Sundelacruz, S.1
Kaplan, D.L.2
-
65
-
-
33846881606
-
Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats
-
Tang TT, Lu B, Yue B, et al. Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats. J Bone Joint Surg Br 2007;89:127-9.
-
(2007)
J Bone Joint Surg Br
, vol.89
, pp. 127-129
-
-
Tang, T.T.1
Lu, B.2
Yue, B.3
-
66
-
-
0037255413
-
Engineered allogeneic mesenchymal stem cells repair femoral segmental defect in rats
-
DOI 10.1016/S0736-0266(02)00108-0, PII S0736026602001080
-
Tsuchida H, Hashimoto J, Crawford E, et al. Engineered allogeneic mesenchymal stem cells repair femoral segmental defect in rats. J Orthop Res 2003;21:44-53. (Pubitemid 36157619)
-
(2003)
Journal of Orthopaedic Research
, vol.21
, Issue.1
, pp. 44-53
-
-
Tsuchida, H.1
Hashimoto, J.2
Crawford, E.3
Manske, P.4
Lou, J.5
-
67
-
-
35348852485
-
Osterix overexpression in mesenchymal stem cells stimulates healing of critical-sized defects in murine calvarial bone
-
DOI 10.1089/ten.2006.0406
-
Tu Q, Valverde P, Li S, et al. Osterix overexpression in mesenchymal stem cells stimulates healing of critical-sized defects in murine calvarial bone. Tissue Eng 2007;13:2431-40. (Pubitemid 47571707)
-
(2007)
Tissue Engineering
, vol.13
, Issue.10
, pp. 2431-2440
-
-
Tu, Q.1
Valverde, P.2
Li, S.3
Zhang, J.4
Yang, P.5
Chen, J.6
-
68
-
-
48349143292
-
Biomechanical concepts of fracture healing in weight-bearing long bones
-
Ulstrup AK. Biomechanical concepts of fracture healing in weight-bearing long bones. Acta Orthop Belg 2008;74:291-302.
-
(2008)
Acta Orthop Belg
, vol.74
, pp. 291-302
-
-
Ulstrup, A.K.1
-
69
-
-
0035101195
-
Adenoviral delivery of LIM mineralization protein-1 induces new-bone formation in vitro and in vivo
-
Viggeswarapu M, Boden SD, Liu Y, et al. Adenoviral delivery of LIM mineralization protein-1 induces new-bone formation in vitro and in vivo. J Bone Joint Surg Am 2001;83-A:364-76. (Pubitemid 32221566)
-
(2001)
Journal of Bone and Joint Surgery - Series A
, vol.83
, Issue.3
, pp. 364-376
-
-
Viggeswarapu, M.1
Boden, S.D.2
Liu, Y.3
Hair, G.A.4
Louis-Ugbo, J.5
Murakami, H.6
Hak, S.K.7
Mayr, M.T.8
Hutton, W.C.9
Titus, L.10
-
70
-
-
41949123855
-
Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect model
-
Virk MS, Conduah A, Park SH, et al. Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect model. Bone 2008;42:921-31.
-
(2008)
Bone
, vol.42
, pp. 921-931
-
-
Virk, M.S.1
Conduah, A.2
Park, S.H.3
-
71
-
-
34548842204
-
Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation
-
Wan DC, Pomerantz JH, Brunet LJ, et al. Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. J Biol Chem 2007;282:26450-9.
-
(2007)
J Biol Chem
, vol.282
, pp. 26450-26459
-
-
Wan, D.C.1
Pomerantz, J.H.2
Brunet, L.J.3
-
72
-
-
27644441812
-
Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats
-
Xu XL, Tang T, Dai K, et al. Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats. Acta Orthop 2005;76:637-46.
-
(2005)
Acta Orthop
, vol.76
, pp. 637-646
-
-
Xu, X.L.1
Tang, T.2
Dai, K.3
-
73
-
-
73349117490
-
Irradiated human chondrocytes expressing bone morphogenetic protein 2 promote healing of osteoporotic bone fracture in rats
-
Yi Y, Choi KB, Lim CL, et al. Irradiated human chondrocytes expressing bone morphogenetic protein 2 promote healing of osteoporotic bone fracture in rats. Tissue Eng Part A 2009;15:2853-63.
-
(2009)
Tissue Eng Part A
, vol.15
, pp. 2853-2863
-
-
Yi, Y.1
Choi, K.B.2
Lim, C.L.3
-
74
-
-
37549048980
-
Healing cranial defects with AdRunx2-transduced marrow stromal cells
-
Zhao Z, Wang Z, Ge C, et al. Healing cranial defects with AdRunx2-transduced marrow stromal cells. J Dent Res 2007;86:1207-11.
-
(2007)
J Dent Res
, vol.86
, pp. 1207-1211
-
-
Zhao, Z.1
Wang, Z.2
Ge, C.3
-
75
-
-
21344464386
-
Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model
-
Zhu W, Rawlins BA, Boachie-Adjei O, et al. Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model. J Bone Miner Res 2004;19:2021-32.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 2021-2032
-
-
Zhu, W.1
Rawlins, B.A.2
Boachie-Adjei, O.3
|