Bioactivity of bovine lung hydrolysates prepared using papain, pepsin, and Alcalase

Journal of Food Biochemistry

Volumn 41, Issue 6, 2017, Pages

  O'Sullivan, Siobhan M ^a   Lafarga, Tomas ^b,c   Hayes, Maria ^c   O'Brien, Nora M ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b IRTA   (Spain)

^c TEAGASC   (Ireland)

Author keywords

anti inflammatory; bovine lung; hydrolysates; Jurkat T cells; RAW264.7 cells

Indexed keywords

BIOACTIVITY; BIOLOGICAL MATERIALS; BIOLOGICAL ORGANS; CELL CULTURE; CELLS; ENZYMATIC HYDROLYSIS; HYDROLYSIS; MAMMALS; NITRIC OXIDE; PAPAIN; PROTEINS;

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY ACTIVITY; ANTI-INFLAMMATORY AGENTS; ANTI-OXIDANT ACTIVITIES; BOVINE LUNG; HYDROLYSATES; PRO-INFLAMMATORY CYTOKINES; RAW 264.7 CELLS;

CYTOLOGY;

EID: 85026348833     PISSN: 01458884     EISSN: 17454514     Source Type: Journal    
DOI: 10.1111/jfbc.12406     Document Type: Article

References (46)

1. Amri, E., & Mamboya, F. (2012). Papain, a plant enzyme of biological importance: A review. American Journal of Biochemistry and Biotechnology, 8, 99–104.
2. Ao, J., & Li, B. (2012). Amino acid composition and antioxidant activities of hydrolysates and peptide fractions from porcine collagen. Food Science and Technology International, 18, 425–434.
3. Benzie, I. F., & Strain, J. J. (1999). Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymology, 299, 15–27.
4. Berne, R. M., Koeppen, B. M., & Stanton, B. A. (2010). Berne & Levy physiology. Philadelphia, PA: Mosby/Elsevier.
5. Cermeño, M., Fitzgerald, R. J., & O'Brien, N. M. (2016). In vitro antioxidant and immunomodulatory activity of transglutaminase-treated sodium caseinate hydrolysates. International Dairy Journal, 63, 107–114.
6. Chang, O. K., Ha, G. E., Jeong, S. G., Seol, K. H., Oh, M. H., Kim, D. W., … Ham, J. S. (2013). Antioxidant activity of porcine skin gelatin hydrolyzed by pepsin and pancreatin. Korean Journal for Food Science of Animal Resources, 33, 493–500.
7. Chen, M., & Li, B. (2012). The effect of molecular weights on the survivability of casein-derived antioxidant peptides after the simulated gastrointestinal digestion. Innovative Food Science & Emerging Technologies, 16, 341–348.
8. Crowley, D., O'Callaghan, Y., McCarthy, A. L., Connolly, A., Fitzgerald, R. J., & O'Brien, N. M. (2017). Aqueous and enzyme-extracted phenolic compounds from brewers' spent grain (BSG): Assessment of their antioxidant potential. Journal of Food Biochemistry, doi:10.1111/jfbc.12370.
9. Darine, S., Christophe, V., & Gholamreza, D. (2010). Production and functional properties of beef lung protein concentrates. Meat Science, 84, 315–322.
10. DE Carvalho-Silva, L. B., Pacheco, M. T. B., Bertoldo, R., DE Carvalho Veloso, C., Teodoro, L. C., Giusti-Paiva, A., … Soncini, R. (2012). Anti-inflammatory activities of enzymatic (alcalase) hydrolysate of a whey protein concentrate. African Journal of Biotechnology, 11, 2993–2999.
11. DI Bernardini, R., Harnedy, P., Bolton, D., Kerry, J., O'neill, E., Mullen, A. M., & Hayes, M. (2011). Antioxidant and antimicrobial peptidic hydrolysates from muscle protein sources and by-products. Food Chemistry, 124, 1296–1307.
12. Dunn, B. M. (2001). Overview of pepsin-like aspartic peptidases. Current Protocols in Protein Science, doi:10.1002/0471140864.ps2103s25
13. Ferraro, V., Anton, M., & Santé-Lhoutellier, V. (2016). The “sisters” α-helices of collagen, elastin and keratin recovered from animal by-products: Functionality, bioactivity and trends of application. Trends in Food Science & Technology, 51, 65–75.
14. Fu, Y., & Zhao, X. H. (2015). Utilization of Chum Salmon (Oncorhynchus keta) skin gelatin hydrolysates to attenuate hydrogen peroxide-induced oxidative injury in rat hepatocyte BRL cell model. Journal of Aquatic Food Product Technology, 24, 648–660.
15. Gu, Y., & Wu, J. (2016). Bovine lactoferrin-derived ACE inhibitory tripeptide LRP also shows antioxidative and anti-inflammatory activities in endothelial cells. Journal of Functional Foods, 25, 375–384.
16. Hartog, A., Cozijnsen, M., DE Vrij, G., & Garssen, J. (2013). Collagen hydrolysate inhibits zymosan-induced inflammation. Experimental Biology and Medicine, 238, 798–802.
17. Himaya, S. W. A., Ngo, D.-H., Ryu, B., & Kim, S.-K. (2012). An active peptide purified from gastrointestinal enzyme hydrolysate of Pacific cod skin gelatin attenuates angiotensin-1 converting enzyme (ACE) activity and cellular oxidative stress. Food Chemistry, 132, 1872–1882.
18. Ichikawa, S., Morifuji, M., Ohara, H., Matsumoto, H., Takeuchi, Y., & Sato, K. (2010). Hydroxyproline-containing dipeptides and tripeptides quantified at high concentration in human blood after oral administration of gelatin hydrolysate. International Journal of Food Sciences and Nutrition, 61, 52–60.
19. Joshi, I., Sudhakar, S., & Nazeer, R. A. (2016). Anti-inflammatory properties of bioactive peptide derived from gastropod influenced by enzymatic hydrolysis. Applied Biochemistry and Biotechnology, 6, 1–13.
20. Karamac, M., Kosinska-Cagnazzo, A., & Kulczyk, A. (2016). Use of different proteases to obtain flaxseed protein hydrolysates with antioxidant activity. International Journal of Molecular Sciences, 17, 1027.
21. Kenny, O. M., Mccarthy, C. M., Brunton, N. P., Hossain, M. B., Rai, D. K., Collins, S. G., … O'Brien, N. M. (2013). Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 mouse macrophages. Life Sciences, 92, 775–782.
22. Kim, D. W., Park, K., Ha, G., Jung, J. R., Chang, O., Ham, J. S., … Jang, A. (2013). Anti-oxidative and neuroprotective activities of pig skin gelatin hydrolysates. Korean Journal for Food Science of Animal Resources, 33, 258–267.
23. Kouguchi, T., Ito, A., Iwai, K., Shimizu, M., Takahata, Y., Suzuki, T., … Tanabe, S. (2012). Chicken collagen hydrolysate-derived peptides inhibit tumor necrosis factor-α-induced inflammatory response in endothelial cells. Food Science and Technology Research, 18, 667–671.
24. Lafarga, T., & Hayes, M. (2014). Bioactive peptides from meat muscle and by-products: Generation, functionality and application as functional ingredients. Meat Science, 98, 227–239.
25. Lafarga, T., & Hayes, M. (2017). Effect of pre-treatment on the generation of dipeptidyl peptidase-IV and prolyl endopeptidase inhibitory hydrolysates from bovine lung. Irish Journal of Agricultural and Food Research. doi:10.1515/ijafr-2017-0002
26. Lee, S.-J., Kim, K. H., Kim, Y.-S., Kim, E.-K., Hwang, J.-W., Lim, B. O., … Park, P.-J. (2012). Biological activity from the gelatin hydrolysates of duck skin by-products. Process Biochemistry, 47, 1150–1154.
27. Li, B., Chen, F., Wang, X., Ji, B., & Wu, Y. (2007). Isolation and identification of antioxidative peptides from porcine collagen hydrolysate by consecutive chromatography and electrospray ionization–mass spectrometry. Food Chemistry, 102, 1135–1143.
28. Malinowski, J., Klempt, M., Clawin-Rädecker, I., Lorenzen, P. C., & Meisel, H. (2014). Identification of a NFκB inhibitory peptide from tryptic β-casein hydrolysate. Food Chemistry, 165, 129–133.
29. Mancinelli, L., DE Angelis, P. M., Annulli, L., Padovini, V., Elgjo, K., & Gianfranceschi, G. L. (2009). A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells. Molecular Cancer, 8, 55.
30. Mao, X.-Y., Cheng, X., Wang, X., & Wu, S.-J. (2011). Free-radical-scavenging and anti-inflammatory effect of yak milk casein before and after enzymatic hydrolysis. Food Chemistry, 126, 484–490.
31. Mirzapour, M., Rezaei, K., Sentandreu, M. A., & Moosavi-Movahedi, A. A. (2016). In vitro antioxidant activities of hydrolysates obtained from Iranian wild almond (Amygdalus scoparia) protein by several enzymes. International Journal of Food Science & Technology, 51, 609–616.
32. Mukhopadhya, A., Noronha, N., Bahar, B., Ryan, M. T., Murray, B. A., Kelly, P. M., … Sweeney, T. (2014). Anti-inflammatory effects of a casein hydrolysate and its peptide-enriched fractions on TNFα-challenged Caco-2 cells and LPS-challenged porcine colonic explants. Food Science & Nutrition, 2, 712–723.
33. Nagodawithana, T., Reed, G., & Taylor, S. (2013). Enzymes in food processing. Amsterdam, Netherlands: Elsevier Science.
34. O'Sullivan, S. M., Lafarga, T., Hayes, M., & O'Brien, N. M. (2017). Anti-proliferative activity of bovine blood hydrolysates towards cancer cells in culture. International Journal of Food Science & Technology, 52, 1049–1056.
35. Phelan, M., Aherne-Bruce, S. A., O'Sullivan, D., Fitzgerald, R. J., & O'Brien, N. M. (2009). Potential bioactive effects of casein hydrolysates on human cultured cells. International Dairy Journal, 19, 279–285.
36. Ramadass, S. K., Jabaris, S. L., Perumal, R. K., Hairulislam, V. I., Gopinath, A., & Madhan, B. (2016). Type I collagen and its daughter peptides for targeting mucosal healing in ulcerative colitis: A new treatment strategy. European Journal of Pharmaceutical Science, 91, 216–224.
37. Ryder, K., Bekhit, A. E. D., Mcconnell, M., & Carne, A. (2016). Towards generation of bioactive peptides from meat industry waste proteins: Generation of peptides using commercial microbial proteases. Food Chemistry, 208, 42–50.
38. Sae-Leaw, T., O'callaghan, Y. C., Benjakul, S., & O'Brien, N. M. (2016). Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysates from seabass (Lates calcarifer) skins. International Journal of Food Science & Technology, 51, 1545–1551.
39. Saiga, A., Tanabe, S., & Nishimura, T. (2003). Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment. Journal of Agricultural and Food Chemistry, 51, 3661–3667.
40. Spittler, A., Reissner, C. M., Oehler, R., Gornikiewicz, A., Gruenberger, T., Manhart, N., … Roth, E. (1999). Immunomodulatory effects of glycine on LPS-treated monocytes: Reduced TNF-alpha production and accelerated IL-10 expression. FASEB J, 13, 563–571.
41. Umayaparvathi, S., Meenakshi, S., Vimalraj, V., Arumugam, M., Sivagami, G., & Balasubramanian, T. (2014). Antioxidant activity and anticancer effect of bioactive peptide from enzymatic hydrolysate of oyster (Saccostrea cucullata). Biomedicine & Preventive Nutrition, 4, 343–353.
42. Vercruysse, L., van Camp, J., & Smagghe, G. (2005). ACE inhibitory peptides derived from enzymatic hydrolysates of animal muscle protein: A review. Journal of Agricultural and Food Chemistry, 53, 8106–8115.
43. Woods, J., Young, A., Gilmore, I., Morris, A., & Bilton, R. (1997). Measurement of menadione-mediated DNA damage in human lymphocytes using the comet assay. Free Radical Research, 26, 113–124.
44. Wu, W., Zhang, M., Sun, C., Brennan, M., Li, H., Wang, G., & Lai, F., Wu, H. (2016). Enzymatic preparation of immunomodulatory hydrolysates from defatted wheat germ (Triticum Vulgare) globulin. International Journal of Food Science & Technology, 51, 2556–2566.
45. Zhang, Y., Olsen, K., Grossi, A., & Otte, J. (2013). Effect of pretreatment on enzymatic hydrolysis of bovine collagen and formation of ACE-inhibitory peptides. Food Chemistry, 141, 2343–2354.
46. Zhao, L., Wang, X., Zhang, X.-L., & Xie, Q.-F. (2016). Purification and identification of anti-inflammatory peptides derived from simulated gastrointestinal digests of velvet antler protein (Cervus elaphus Linnaeus). Journal of Food & Drug Analysis, 24, 376–384.