A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Mancinelli, Loretta ^a   De Angelis, Paula M ^b   Annulli, Lucia ^a   Padovini, Valentina ^a   Elgjo, Kjell ^b   Gianfranceschi, Gian Luigi ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CHECKPOINT KINASE 1; CHROMATIN PROTEIN; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DNA; DNA BINDING PROTEIN; UNCLASSIFIED DRUG; CYCLIN B; PEPTIDE; VEGETABLE PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS INHIBITION; DRUG DNA INTERACTION; DRUG ISOLATION; ENZYME INACTIVATION; HELA CELL; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PROTEIN EXPRESSION; UTERINE CERVIX CANCER; WHEAT; CELL CYCLE; CELL GROWTH; CHEMISTRY; CHROMATIN; DRUG EFFECT; ISOLATION AND PURIFICATION; METABOLISM;

EUKARYOTA; PROKARYOTA; TRITICUM AESTIVUM;

APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL GROWTH PROCESSES; CHROMATIN; CYCLIN B; DNA DAMAGE; DNA-BINDING PROTEINS; G2 PHASE; HELA CELLS; HUMANS; PEPTIDES; PLANT PROTEINS; S PHASE; TRITICUM;

EID: 68949214510     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-55     Document Type: Article

References (43)

1. Werner D Neuer-Nitsche B Discontinuities of peptide nature in DNA Progress in nonhistone protein research Boca Raton FL: CRC Press Bekhor I, Mirell CJ, Liew CC 1989, 3:99-118.
2. Gianfranceschi GL Amici D Guglielmi L Restrinction of template capacity of rat liver chromatin by a non-histone peptide from calf thymus Nature 1976, 262:622-623. 10.1038/262622a0 958432
3. Gianfranceschi GL Guglielmi L Amici D Bossa F Barra D Petruzzelli R Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure Mol Biol Rep 1977, 3:429-436. 10.1007/ BF00808384 593273
4. Coderoni S Miano A Bramucci M Felici F Paparelli M Amici D Gianfranceschi GL Isolation and characterization of small phosphorylated peptides controlling transcription "in vitro" from trout testis chromatin DNA Physiol Chem Phys Med 1988, 20:91-108.
5. Manera E Manchiotti L Lugaro G An improved method for the isolation of deprimerones from spermatozoa chromatin IRCS Med Sci 1984, 12:745-746.
6. Mancinelli L Castigli E Qualadrucci P Gianfranceschi GL Bramucci M Miano A Amici D Small acidic peptides from wheat germ chromatin Physiol Chem Phys Med NMR 1992, 24:97-107. 1508994
7. Felici F Cardellini E Miano A Bramucci M Piccinini G Amici D Gianfranceschi GL Small acidic peptides are bound to E. coli DNA Mol Biol Rep 1991, 15:9-18. 10.1007/BF00369895 1875921
8. Felici F Miano A Bramucci M Piccinini G Amici D Gianfranceschi GL Small acidic peptides are bound to lambda phage DNA Med Sci Res 1991, 19:549-550.
9. Gianfranceschi GL Barra D Bossa F Coderoni S Paparelli M Venanzi F Cicconi F Amici D Small peptides controlling transcription in vitro are bound to chromatin DNA Biochim Biophys Acta 1982, 699:138-148. 6758850
10. Amici D Rossi GB Cioè L Matarese GP Dolei A Gianfranceschi GL Low-molecular-weight peptide inhibits RNA synthesis in human leukemic and phytohemagglutinin-stimulated leukocites and globin mRNA transcription in differentiating Friends cells Proc Natl Acad Sci USA 1977, 74:3869-3873. 431764 269438 10.1073/pnas.74.9.3869
11. Castigli E Mancinelli L Franceschini M Gianfranceschi GL Bramucci M Miano A Amici D Small acidic peptides from wheat germ chromatin Physiol Chem Med 1992, 24:109-117.
12. Gianfranceschi GL Amici D Guglielmi L Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus Mol Biol Rep 1976, 3:55-64. 10.1007/BF00357209 1034203
13. Gianfranceschi GL Amici D Guglielmi L Amplification of template capacity of mammalian DNA following extraction of low molecular weight peptides Physiol Chem Phys 1979, 11:507-515. 95050
14. Gianfranceschi GL Hillar M Chan JT Amici D Low molecular weight peptidic fraction in the chromatin from normal and cancer cells control of transcription Molec Biol Rep 1980, 6:95-103. 10.1007/BF00778436
15. Gianfranceschi GL Barra D Coderoni S Paparelli M Venanzi F Amici D DNA-binding peptides from rat liver and Novikoff hepatoma cells: quantitative level and possible biochemical differences Molec Biol Rep 1983, 9:169-174. 10.1007/BF00775363
16. Mancinelli L Chillemi F Cardellini E Marsili V Giavarini F De Angelis L Lugaro G Gianfranceschi GL Molecular models of acidic peptides from pea bud chromatin and seminal plasma. Divalent cations-mediated interaction with DNA Biol Chem 1999, 380:31-40. 10.1515/BC.1999.004 10064134
17. 2 arrest in response to topoisomerase II inhibitors: The role of p53 Cancer Res 2003 63 4074 4081 12874009
18. Kozaki Y Kubo M Ariki T Onishi T Zhu D Muramatu M Properties of three proteinases functioning at G1, S and G2 phases in HeLa cells and their inhibition by guanidino- and amidino-acid esters Biol Pharm Bull 1994, 17:185-191. 8205113
19. Jeganathan KB Malureanu L van Deursen JM The Rae1-Nup98 complex prevents aneuploidy by inhibiting securing degradation Nature 2005, 438:1036-1039. 10.1038/nature04221 16355229
20. Lugaro G Campagnari F Moretti R Casellato MM Inhibition of DNA polymerization and DNA transcription to RNA by seminal plasma peptides Biochim Biophys Acta 1988, 950:420-428. 3167061
21. Singht NP Mc Coy MT Tice RR Schneider EL A simple technique for quantitation of low level of DNA damage in individual cells Exp Cell Res 1988, 175:184-191. 10.1016/0014-4827(88)90265-0 3345800
22. Hochegger H Takeda S Hunt T Cyclin-dependent kinases and cell-cycle transitions: Does one fill all? Nature 2008, 9:910-916.
23. Ivanov VT Karelin AA Philippova MM Nazimov IV Pletnev VZ Hemoglobin as source of endogenous bioactive peptides: The concept of tissue-specific peptide pool Biopolymers 1997, 42:171-188. 10.1002/ (SICI)1097-0282(1997)43:2<171::AID-BIP10>3.0.CO;2-O
24. Karelin AA Blishchenko EY Ivanov VT Fragments of functional proteins: role in endocrine regulation Neurochem Res 1999, 24:1117-1124. 10.1023/ A:1020756202644 10485582
25. Paukovitis WR Laerum OD Isolation and synthesis of a hemoregulatory peptide Z Zellforsch Mikrosk Anat 1982, 37:1297-1300.
26. Elgjo K Reichelt KL Purification and characterization of a mitosis inhibiting epidermal peptide Cell Biol Int Rep 1984, 5:379-382. 10.1016/ 0309-1651(84)90140-1
27. Skraastad O Fossli T Edminson PD Reichelt KL Purification and characterization of a mitosis inhibiting tripeptide from mouse intestinal extracts Epithelia 1987, 1:107-119.
28. Reichelt KL Paulsen JE Elgjo K Isolation of a growth and mitosis inhibitory peptide from mouse liver Virchows Arch Abt B Zellpathol 1990, 59:137-142.
29. Blagosklonny MV Pardee AB The restriction point of the cell cycle Cell Cycle 2002, 1(Suppl 2):103-110.
30. Didier C Cavalier C Quaranta M Galcera M-O Demur c Laurent G Manenti S Ducommun B G2/M checkpoint stringency is a key parameter in the esnsivity of AML cells to genotoxic stress Oncogene 2008, 27:3811-3820. 10.1038/sj.onc.1211041 18212737
31. Bartek J Lukas J DNA damage checkpoints: From initiation to recovery or adaption Curr Opin Cell Biol 2007, 19:238-245. 10.1016/j.ceb.2007.02.009 17303408
32. Taylor WR Stark GR Regulation of the G2/M transition by p53 Oncogene 2001, 20:1803-1815. 10.1038/sj.onc.1204252 11313928
33. Jo HJ Song JD Kim Km Cho YH Kim KH Park YC Dially disulfide induces reversible G2/M phase arrest on a p53-independent mechanism in human colon cancer HCT-116 cells Oncol Rep 2008, 19:275-280. 18097607
34. Southern A Herrington CS Disruption of cell cycle control by hu man papillomaviruses with special reference to cervical carcinoma Int J Gynecol Cancer 2000, 10:263-274. 10.1046/j.1525-1438.2000.010004263.x 11240685
35. Castedo M Perfettini JL Roumier T Kroemer G Cyclin-dependent Kinase1: linking apoptosis to cell cycle and mitotic catastrophe Cell Death & Diff 2002, 9:1287-1293. 10.1038/sj.cdd.4401130
36. Gianfranceschi GL Czerwinski A Angiolillo A Marsili V Castigli E Mancinelli L Miano A Bramucci M Amici D Molecular models of small phosphorylated chromatin peptides. Structure-function relationship and regulatory activity on in vitro transcription and on cell growth and differentiation Peptides 1994, 15:7-13. 10.1016/0196-9781(94)90163-5 8015983
37. Mitsuyoshi M Kazuhiro M Yaeta E Kunio T Detection and partial characterization of the chromatin associated proteases of yeast Saccaromyces cerevisiae Eur J Biochem 1985, 2:345-350.
38. Vindeløv LL Christensen IJ Nissen NI A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis Cytometry 1983, 3:323-327. 10.1002/cyto.990030503 6188586
39. Gorczyca W Gong J Darzynkiewicz Z Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl individual trasferase and nick translation assays Cancer Res 1993, 53:1945-1951. 8467513
40. Castigli E Mancinelli L Mariggiò MA Gianfranceschi GL Possible specific activation of RNA synthesis in PC-12 cell isolated nuclei by small acidic peptides Am J Physiol Society 1993, 265:1220-1223.
41. Laemmli UK Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 1970, 227:680-685. 10.1038/227680a0 5432063
42. Towbin M Stahelin T Gordon J Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheet: Procedure and some applications Proc Natl Acad Sci USA 1979, 76:4350-4354. 411572 388439 10.1073/pnas.76.9.4350
43. 125IdUrd Int J Radiat Biol 1993 64 Suppl 4 349 358 10.1080/ 09553009314551531