Collagen hydrolysate inhibits zymosan-induced inflammation

Experimental Biology and Medicine

Volumn 238, Issue 7, 2013, Pages 798-802

  Hartog, Anita ^a,b   Cozijnsen, Miranda ^a,b   de Vrij, Gerrit ^b   Garssen, Johan ^a,b  

^a DANONE RESEARCH   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Collagen hydrolysate; Glycine; GlyR; inflammation

Indexed keywords

COLLAGEN DERIVATIVE; COLLAGEN HYDROLYSATE; GLYCINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; DRUG DOSE COMPARISON; ENZYME IMMUNOASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; OTITIS;

COLLAGEN HYDROLYSATE; GLYCINE; GLYR; INFLAMMATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; EAR; GLYCINE; HYDROLYSIS; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; PROTEIN HYDROLYSATES; SKIN; ZYMOSAN;

EID: 84884170710     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213480740     Document Type: Article

References (23)

1. Froh M,Thurman RG,Wheeler MD.Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes.Am J Physiol Gastrointest Liver Physiol. 2002;283:G856-63.
2. Wheeler M,Stachlewitz RF,Yamashina S,Ikejima K,Morrow AL,Thurman RG.Glycine-gated chloride channels in neutrophils attenuate calcium influx and superoxide production.FASEB J. 2000;14:476-84.
3. Zhong Z,Wheeler MD,Li X,Froh M,Schemmer P,Yin M,Bunzendaul H,Bradford B,Lemasters JJ.L-glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent.Curr Opin Clin Nutr Metab Care. 2003;6:229-40.
4. Ikejima K,Iimuro Y,Forman DT,Thurman RG.A diet containing glycine improves survival in endotoxin shock in the rat.Am J Physiol. 1996;271:G97-103.
5. Spittler A,Reissner CM,Oehler R,Gornikiewicz A,Gruenberger T,Manhart N,Brodowicz T,Mittlboeck M,Boltz-Nitulescu G,Roth E.Immunomodulatory effects of glycine on LPS-treated monocytes: reduced TNF-alpha production and accelerated IL-10 expression.FASEB J. 1999;13:563-71.
6. Blancas-Flores G,Alarcon-Aguilar FJ,Garcia-Macedo R,Imanza-Perez JC,Flores-Saenz JL,Roman-Ramos R,Ventura-Gallegos JL,Kumate J,Zentella-Dehesa A,Cruz M.Glycine suppresses TNF-alpha-induced activation of NF-kappaB in differentiated 3T3-L1 adipocytes.Eur J Pharmacol. 2012;689:270-7.
7. Hasegawa S,Ichiyama T,Sonaka I,Ohsaki A,Okada S,Wakiguchi H,Kudo K,Kittaka S,Hara M,Furukawa S.Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells.Clin Exp Immunol. 2012;167:269-74.
8. Hartog A,Leenders I,van der Kraan PM,Garssen J.Anti-inflammatory effects of orally ingested lactoferrin and glycine in different zymosan-induced inflammation models: evidence for synergistic activity.Int Immunopharmacol. 2007;7:1784-92.
9. Li X,Bradford BU,Wheeler MD,Stimpson SA,Pink HM,Brodie TA,Schwab JH,Thurman RG.Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel.Infect Immun. 2001;69:5883-91.
10. Stoffels B,Turler A,Schmidt J,Nazir A,Tsukamoto T,Moore BA,Schnurr C,Kalff JC,Bauer AJ.Anti-inflammatory role of glycine in reducing rodent postoperative inflammatory ileus.Neurogastroenterol Motil. 2011;23:76-87,e8.
11. Alarcon-Aguilar FJ,Almanza-Perez J,Blancas G,Angeles S,Garcia-Macedo R,Roman R,Cruz M.Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice.Eur J Pharmacol. 2008;599:152-8.
12. Walrand S,Chiotelli E,Noirt F,Mwewa S,Lassel T.Consumption of a functional fermented milk containing collagen hydrolysate improves the concentration of collagen-specific amino acids in plasma.J Agric Food Chem. 2008;56:7790-5.
13. Benito-Ruiz P,Camacho-Zambrano MM,Carrillo-Arcentales JN,Mestanza-Peralta MA,Vallejo-Flores CA,Vargas-Lopez SV,Villacis-Tamayo RA,Zurita-Gavilanes LA.A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort.Int J Food Sci Nutr. 2009;60:99-113.
14. Bello AE,Oesser S.Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature.Curr Med Res Opin. 2006;22:2221-32.
15. Carpenter RL,Peel JB,Carpenter MR,Lowndes J,Angelopoulos T,Rippe JM.Effectiveness of a collagen hydrolysate-based supplement on joint pain, range of motion and muscle function in individuals with mild osteoarthritis of the knee: a randomized clinical trial.Ann Rheum Dis. 2005;64:476-476.
16. Bruyere O,Zegels B,Leonori L,Rabenda V,Janssen A,Bourges C,Reginster JY.Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study.Complement Ther Med. 2012;20:124-30.
17. Hougee S,Hartog A,Sanders A,Graus YM,Hoijer MA,Garssen J,van den Berg WB,van Beuningen HM,Smit HF.Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice.Eur J Pharmacol. 2006;531:264-9.
18. Erdo F,Torok K,Aranyi P,Szekely JI.A new assay for antiphlogistic activity: zymosan-induced mouse ear inflammation.Agents Actions. 1993;39:137-42.
19. Castro GA,Sgarbieri VC,Carvalho JE,Tinti SV,Possenti A.Protective effect of collagen derivates on the ulcerative lesions caused by oral administration of ethanol.J Med Food. 2007;10:154-8.
20. Castro GA,Carvalho JE,Tinti SV,Possenti A,Sgarbieri VC.Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.J Med Food. 2010;13:83-90.
21. Zhang Y,Kouguchi T,Shimizu K,Sato M,Takahata Y,Morimatsu F.Chicken collagen hydrolysate reduces proinflammatory cytokine production in C57BL/6.KOR-ApoEshl mice.J Nutr Sci Vitaminol (Tokyo). 2010;56:208-10.
22. Van Vijven JP,Luijsterburg PA,Verhagen AP,van Osch GJ,Kloppenburg M,Bierma-Zeinstra SM.Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review.Osteoarthr Cartilage. 2012;20:809-21.
23. Song YP,Schlesinger F,Ragancokova D,Calixto R,Dengler R,Krampfl K.Changes in extracellular pH affect glycine receptor channels expressed in HEK 293 cells.Eur J Pharmacol. 2010;636:59-64.