-
1
-
-
84903602651
-
Bacterial persisters: Formation, eradication, and experimental systems
-
Helaine, S. & Kugelberg, E. Bacterial persisters: formation, eradication, and experimental systems. Trends Microbiol. 22, 417-424 (2014).
-
(2014)
Trends Microbiol.
, vol.22
, pp. 417-424
-
-
Helaine, S.1
Kugelberg, E.2
-
2
-
-
85006247350
-
Mechanisms of bacterial persistence during stress and antibiotic exposure
-
Harms, A., Maisonneuve, E. & Gerdes, K. Mechanisms of bacterial persistence during stress and antibiotic exposure. Science 354, aaf4268 (2016).
-
(2016)
Science
, vol.354
, pp. aaf4268
-
-
Harms, A.1
Maisonneuve, E.2
Gerdes, K.3
-
3
-
-
84992481960
-
Molecular mechanisms and clinical implications of bacterial persistence
-
Michiels, J. E., Van den Bergh, B., Verstraeten, N. & Michiels, J. Molecular mechanisms and clinical implications of bacterial persistence. Drug Resist. Updat. 29, 76-89 (2017).
-
(2017)
Drug Resist. Updat.
, vol.29
, pp. 76-89
-
-
Michiels, J.E.1
Van Den Bergh, B.2
Verstraeten, N.3
Michiels, J.4
-
4
-
-
84940903617
-
A novel point mutation promotes growth phase-dependent daptomycin tolerance in Staphylococcus aureus
-
Mechler, L. et al. A novel point mutation promotes growth phase-dependent daptomycin tolerance in Staphylococcus aureus. Antimicrob. Agents Chemother. 59, 5366-5376 (2015).
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 5366-5376
-
-
Mechler, L.1
-
5
-
-
84975170433
-
Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence
-
Van den Bergh, B. et al. Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence. Nat. Microbiol. 1, 16020 (2016).
-
(2016)
Nat. Microbiol.
, vol.1
, pp. 16020
-
-
Van Den Bergh, B.1
-
6
-
-
84879072389
-
Microbial persistence and the road to drug resistance
-
Cohen, N. R., Lobritz, M. A. & Collins, J. J. Microbial persistence and the road to drug resistance. Cell Host Microbe 13, 632-642 (2013).
-
(2013)
Cell Host Microbe
, vol.13
, pp. 632-642
-
-
Cohen, N.R.1
Lobritz, M.A.2
Collins, J.J.3
-
7
-
-
85013066181
-
Antibiotic tolerance facilitates the evolution of resistance
-
Levin-Reisman, I. et al. Antibiotic tolerance facilitates the evolution of resistance. Science 355, 826-830 (2017).
-
(2017)
Science
, vol.355
, pp. 826-830
-
-
Levin-Reisman, I.1
-
8
-
-
84964105753
-
Observations on the mechanism of action of penicillin
-
Hobby, G. L., Meyer, K. & Chaffee, E. Observations on the mechanism of action of penicillin. Exp. Biol. Med. 50, 281-285 (1942).
-
(1942)
Exp. Biol. Med.
, vol.50
, pp. 281-285
-
-
Hobby, G.L.1
Meyer, K.2
Chaffee, E.3
-
9
-
-
50349141358
-
Treatment of staphylococcal infections with penicillin by intermittant sterilisation
-
Bigger, J. W. Treatment of staphylococcal infections with penicillin by intermittant sterilisation. Lancet 244, 497-500 (1944).
-
(1944)
Lancet
, vol.244
, pp. 497-500
-
-
Bigger, J.W.1
-
10
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L. & Leibler, S. Bacterial persistence as a phenotypic switch. Science 305, 1622-1625 (2004).
-
(2004)
Science
, vol.305
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
11
-
-
79953279193
-
Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
-
Adams, K. N. et al. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145, 39-53 (2011).
-
(2011)
Cell
, vol.145
, pp. 39-53
-
-
Adams, K.N.1
-
12
-
-
84871859996
-
Dynamic persistence of antibiotic-stressed mycobacteria
-
Wakamoto, Y. et al. Dynamic persistence of antibiotic-stressed mycobacteria. Science 339, 91-95 (2013).
-
(2013)
Science
, vol.339
, pp. 91-95
-
-
Wakamoto, Y.1
-
13
-
-
84897948007
-
The role of metabolism in bacterial persistence
-
Amato, S. et al. The role of metabolism in bacterial persistence. Front. Microbiol. 5, 70 (2014).
-
(2014)
Front. Microbiol.
, vol.5
, pp. 70
-
-
Amato, S.1
-
14
-
-
84892181925
-
Internalization of Salmonella by macrophages induces formation of nonreplicating persisters
-
Helaine, S. et al. Internalization of Salmonella by macrophages induces formation of nonreplicating persisters. Science 343, 204-208 (2014).
-
(2014)
Science
, vol.343
, pp. 204-208
-
-
Helaine, S.1
-
15
-
-
0037321598
-
The basis of persistent bacterial infections
-
Rhen, M., Eriksson, S., Clements, M., Bergström, S. & Normark, S. J. The basis of persistent bacterial infections. Trends Microbiol. 11, 80-86 (2003).
-
(2003)
Trends Microbiol.
, vol.11
, pp. 80-86
-
-
Rhen, M.1
Eriksson, S.2
Clements, M.3
Bergström, S.4
Normark, S.J.5
-
16
-
-
84878098314
-
Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response
-
Grant, S. S. & Hung, D. T. Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response. Virulence 4, 273-283 (2013).
-
(2013)
Virulence
, vol.4
, pp. 273-283
-
-
Grant, S.S.1
Hung, D.T.2
-
17
-
-
0020335129
-
Precise estimation of the numbers of chronic carriers of Salmonella Typhi in Santiago, Chile, an endemic area
-
Levine, M. M., Black, R. E. & Lanata, C. Precise estimation of the numbers of chronic carriers of Salmonella Typhi in Santiago, Chile, an endemic area. J. Infect. Dis. 146, 724-726 (1982).
-
(1982)
J. Infect. Dis.
, vol.146
, pp. 724-726
-
-
Levine, M.M.1
Black, R.E.2
Lanata, C.3
-
18
-
-
0028147619
-
Cancer mortality in chronic typhoid and paratyphoid carriers
-
Caygill, C. P. J., Hill, M. J., Braddick, M. & Sharp, J. C. M. Cancer mortality in chronic typhoid and paratyphoid carriers. Lancet 343, 83-84 (1994).
-
(1994)
Lancet
, vol.343
, pp. 83-84
-
-
Caygill, C.P.J.1
Hill, M.J.2
Braddick, M.3
Sharp, J.C.M.4
-
19
-
-
23944494081
-
Typhoid and paratyphoid fever
-
Bhan, M. K., Bahl, R. & Bhatnagar, S. Typhoid and paratyphoid fever. Lancet 366, 749-762 (2005).
-
(2005)
Lancet
, vol.366
, pp. 749-762
-
-
Bhan, M.K.1
Bahl, R.2
Bhatnagar, S.3
-
20
-
-
0028292275
-
Helicobacter pylori infection and the risk for duodenal and gastric ulceration
-
Nomura, A., Stemmermann, G. N., Chyou, P.-H., Perez-Perez, G. I. & Blaser, M. J. Helicobacter pylori infection and the risk for duodenal and gastric ulceration. Ann. Intern. Med. 120, 977-981 (1994).
-
(1994)
Ann. Intern. Med.
, vol.120
, pp. 977-981
-
-
Nomura, A.1
Stemmermann, G.N.2
Chyou, P.-H.3
Perez-Perez, G.I.4
Blaser, M.J.5
-
21
-
-
0025935635
-
Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma
-
Wotherspoon, A. C., Ortiz-Hidalgo, C., Falzon, M. R. & Isaacson, P. G. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 338, 1175-1176 (1991).
-
(1991)
Lancet
, vol.338
, pp. 1175-1176
-
-
Wotherspoon, A.C.1
Ortiz-Hidalgo, C.2
Falzon, M.R.3
Isaacson, P.G.4
-
22
-
-
0033200278
-
Association of Helicobacter pylori infection with gastric carcinoma: A meta-analysis
-
Eslick, G. D., Lim, L. L.-Y., Byles, J. E., Xia, H. H.-X. & Talley, N. J. Association of Helicobacter pylori infection with gastric carcinoma: a meta-analysis. Am. J. Gastroenterol. 94, 2373-2379 (1999).
-
(1999)
Am. J. Gastroenterol.
, vol.94
, pp. 2373-2379
-
-
Eslick, G.D.1
Lim, L.L.-Y.2
Byles, J.E.3
Xia, H.H.-X.4
Talley, N.J.5
-
23
-
-
0347091999
-
Tuberculosis persistence, latency, and drug tolerance
-
Gomez, J. E. & McKinney, J. D. M. tuberculosis persistence, latency, and drug tolerance. Tuberculosis 84, 29-44 (2004).
-
(2004)
Tuberculosis
, vol.84
, pp. 29-44
-
-
Gomez, J.E.1
McKinney, J.D.M.2
-
24
-
-
0023264423
-
Association between specific plasmids and relapse in typhoid fever
-
Gotuzzo, E. et al. Association between specific plasmids and relapse in typhoid fever. J. Clin. Microbiol. 25, 1779-1781 (1987).
-
(1987)
J. Clin. Microbiol.
, vol.25
, pp. 1779-1781
-
-
Gotuzzo, E.1
-
25
-
-
0025100976
-
Recurring urinary tract infection: Incidence and risk factors
-
Foxman, B. Recurring urinary tract infection: incidence and risk factors. Am. J. Public Health 80, 331-333 (1990).
-
(1990)
Am. J. Public Health
, vol.80
, pp. 331-333
-
-
Foxman, B.1
-
26
-
-
0030950679
-
Intracellular reservoir of Streptococcus pyogenes in vivo: A possible explanation for recurrent pharyngotonsillitis
-
Österlund, A., Popa, R., Nikkilä, T., Scheynius, A. & Engstrand, L. Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis. Laryngoscope 107, 640-647 (1997).
-
(1997)
Laryngoscope
, vol.107
, pp. 640-647
-
-
Österlund, A.1
Popa, R.2
Nikkilä, T.3
Scheynius, A.4
Engstrand, L.5
-
27
-
-
42549164149
-
Medical biofilms
-
Bryers, J. D. Medical biofilms. Biotechnol. Bioeng. 100, 1-18 (2008).
-
(2008)
Biotechnol. Bioeng.
, vol.100
, pp. 1-18
-
-
Bryers, J.D.1
-
28
-
-
0036225688
-
Lung infections associated with cystic fibrosis
-
Lyczak, J. B., Cannon, C. L. & Pier, G. B. Lung infections associated with cystic fibrosis. Clin. Microbiol. Rev. 15, 194-222 (2002).
-
(2002)
Clin. Microbiol. Rev.
, vol.15
, pp. 194-222
-
-
Lyczak, J.B.1
Cannon, C.L.2
Pier, G.B.3
-
29
-
-
78049522796
-
Long-term impacts of antibiotic exposure on the human intestinal microbiota
-
Jernberg, C., Löfmark, S., Edlund, C. & Jansson, J. K. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology 156, 3216-3223 (2010).
-
(2010)
Microbiology
, vol.156
, pp. 3216-3223
-
-
Jernberg, C.1
Löfmark, S.2
Edlund, C.3
Jansson, J.K.4
-
30
-
-
33744457946
-
Antigenic variation with a twist - The Borrelia story
-
Norris, S. J. Antigenic variation with a twist - the Borrelia story. Mol. Microbiol. 60, 1319-1322 (2006).
-
(2006)
Mol. Microbiol.
, vol.60
, pp. 1319-1322
-
-
Norris, S.J.1
-
31
-
-
0035252656
-
Hijacking and exploitation of IL-10 by intracellular pathogens
-
Redpath, S., Ghazal, P. & Gascoigne, N. R. J. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol. 9, 86-92 (2001).
-
(2001)
Trends Microbiol.
, vol.9
, pp. 86-92
-
-
Redpath, S.1
Ghazal, P.2
Gascoigne, N.R.J.3
-
32
-
-
0041884953
-
Phagosome maturation: A few bugs in the system
-
Scott, C. C., Botelho, R. J. & Grinstein, S. Phagosome maturation: a few bugs in the system. J. Membr. Biol. 193, 137-152 (2003).
-
(2003)
J. Membr. Biol.
, vol.193
, pp. 137-152
-
-
Scott, C.C.1
Botelho, R.J.2
Grinstein, S.3
-
33
-
-
84994708561
-
The Salmonella effector SteD mediates MARCH8-dependent ubiquitination of MHC II molecules and inhibits T cell activation
-
Bayer-Santos, E. et al. The Salmonella effector SteD mediates MARCH8-dependent ubiquitination of MHC II molecules and inhibits T cell activation. Cell Host Microbe 20, 584-595 (2016).
-
(2016)
Cell Host Microbe
, vol.20
, pp. 584-595
-
-
Bayer-Santos, E.1
-
34
-
-
84899134307
-
Bacteria fighting back - How pathogens target and subvert the host innate immune system
-
Reddick, L. E. & Alto, N. M. Bacteria fighting back - how pathogens target and subvert the host innate immune system. Mol. Cell 54, 321-328 (2014).
-
(2014)
Mol. Cell
, vol.54
, pp. 321-328
-
-
Reddick, L.E.1
Alto, N.M.2
-
35
-
-
0035992362
-
Mechanisms of antibiotic resistance in bacterial biofilms
-
Stewart, P. S. Mechanisms of antibiotic resistance in bacterial biofilms. Int. J. Med. Microbiol. 292, 107-113 (2002).
-
(2002)
Int. J. Med. Microbiol.
, vol.292
, pp. 107-113
-
-
Stewart, P.S.1
-
36
-
-
4444349432
-
Persistent bacterial infections: The interface of the pathogen and the host immune system
-
Monack, D. M., Mueller, A. & Falkow, S. Persistent bacterial infections: the interface of the pathogen and the host immune system. Nat. Rev. Microbiol. 2, 747-765 (2004).
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 747-765
-
-
Monack, D.M.1
Mueller, A.2
Falkow, S.3
-
37
-
-
84878013732
-
Life in the human stomach: Persistence strategies of the bacterial pathogen Helicobacter pylori
-
Salama, N. R., Hartung, M. L. & Muller, A. Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat. Rev. Microbiol. 11, 385-399 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 385-399
-
-
Salama, N.R.1
Hartung, M.L.2
Muller, A.3
-
38
-
-
0033591467
-
Bacterial biofilms: A common cause of persistent infections
-
Costerton, J. W., Stewart, P. S. & Greenberg, E. P. Bacterial biofilms: a common cause of persistent infections. Science 284, 1318-1322 (1999).
-
(1999)
Science
, vol.284
, pp. 1318-1322
-
-
Costerton, J.W.1
Stewart, P.S.2
Greenberg, E.P.3
-
39
-
-
0141955237
-
Compromised host defense on Pseudomonas aeruginosa biofilms: Characterization of neutrophil and biofilm interactions
-
Jesaitis, A. J. et al. Compromised host defense on Pseudomonas aeruginosa biofilms: characterization of neutrophil and biofilm interactions. J. Immunol. 171, 4329-4339 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 4329-4339
-
-
Jesaitis, A.J.1
-
40
-
-
84879456358
-
Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae
-
Domenech, M., Ramos-Sevillano, E., García, E., Moscoso, M. & Yuste, J. Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae. Infect. Immun. 81, 2606-2615 (2013).
-
(2013)
Infect. Immun.
, vol.81
, pp. 2606-2615
-
-
Domenech, M.1
Ramos-Sevillano, E.2
García, E.3
Moscoso, M.4
Yuste, J.5
-
41
-
-
0036274370
-
Tuberculosis unleashed: The impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis
-
Lawn, S. D., Butera, S. T. & Shinnick, T. M. Tuberculosis unleashed: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis. Microbes Infect. 4, 635-646 (2002).
-
(2002)
Microbes Infect.
, vol.4
, pp. 635-646
-
-
Lawn, S.D.1
Butera, S.T.2
Shinnick, T.M.3
-
42
-
-
0035992114
-
Patient compliance with antibiotic treatment for respiratory tract infections
-
Kardas, P. Patient compliance with antibiotic treatment for respiratory tract infections. J. Antimicrob. Chemother. 49, 897-903 (2002).
-
(2002)
J. Antimicrob. Chemother.
, vol.49
, pp. 897-903
-
-
Kardas, P.1
-
43
-
-
80052672933
-
Antibiotics in critically ill patients: A systematic review of the pharmacokinetics of β-lactams
-
Gonçalves-Pereira, J. & Póvoa, P. Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams. Crit. Care 15, R206 (2011).
-
(2011)
Crit. Care
, vol.15
, pp. R206
-
-
Gonçalves-Pereira, J.1
Póvoa, P.2
-
44
-
-
84923611351
-
Molecular mechanisms of antibiotic resistance
-
Blair, J. M. A., Webber, M. A., Baylay, A. J., Ogbolu, D. O. & Piddock, L. J. V. Molecular mechanisms of antibiotic resistance. Nat. Rev. Microbiol. 13, 42-51 (2015).
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 42-51
-
-
Blair, J.M.A.1
Webber, M.A.2
Baylay, A.J.3
Ogbolu, D.O.4
Piddock, L.J.V.5
-
45
-
-
84964318468
-
Distinguishing between resistance, tolerance and persistence to antibiotic treatment
-
Brauner, A., Fridman, O., Gefen, O. & Balaban, N. Q. Distinguishing between resistance, tolerance and persistence to antibiotic treatment. Nat. Rev. Microbiol. 14, 320-330 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 320-330
-
-
Brauner, A.1
Fridman, O.2
Gefen, O.3
Balaban, N.Q.4
-
46
-
-
77955628762
-
Persister cells
-
Lewis, K. Persister cells. Annu. Rev. Microbiol. 64, 357-372 (2010).
-
(2010)
Annu. Rev. Microbiol.
, vol.64
, pp. 357-372
-
-
Lewis, K.1
-
47
-
-
84908456444
-
Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy
-
Claudi, B. et al. Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy. Cell 158, 722-733 (2014).
-
(2014)
Cell
, vol.158
, pp. 722-733
-
-
Claudi, B.1
-
48
-
-
84858114217
-
High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella typhimurium disease
-
Okoro, C. K. et al. High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella typhimurium disease. Clin. Infect. Dis. 54, 955-963 (2012).
-
(2012)
Clin. Infect. Dis.
, vol.54
, pp. 955-963
-
-
Okoro, C.K.1
-
49
-
-
0029119911
-
Chromosomal restriction fragment length polymorphism analysis of Escherichia coli strains causing recurrent urinary tract infections in young women
-
Russo, T. A., Stapleton, A., Wenderoth, S., Hooton, T. M. & Stamm, W. E. Chromosomal restriction fragment length polymorphism analysis of Escherichia coli strains causing recurrent urinary tract infections in young women. J. Infect. Dis. 172, 440-445 (1995).
-
(1995)
J. Infect. Dis.
, vol.172
, pp. 440-445
-
-
Russo, T.A.1
Stapleton, A.2
Wenderoth, S.3
Hooton, T.M.4
Stamm, W.E.5
-
50
-
-
0026687909
-
DNA restriction fragment length polymorphism differentiates recurrence from relapse in treatment failures of Streptococcus pyogenes pharyngitis
-
Bingen, E. et al. DNA restriction fragment length polymorphism differentiates recurrence from relapse in treatment failures of Streptococcus pyogenes pharyngitis. J. Med. Microbiol. 37, 162-164 (1992).
-
(1992)
J. Med. Microbiol.
, vol.37
, pp. 162-164
-
-
Bingen, E.1
-
51
-
-
84907879368
-
Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations
-
Fridman, O., Goldberg, A., Ronin, I., Shoresh, N. & Balaban, N. Q. Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations. Nature 513, 418-421 (2014).
-
(2014)
Nature
, vol.513
, pp. 418-421
-
-
Fridman, O.1
Goldberg, A.2
Ronin, I.3
Shoresh, N.4
Balaban, N.Q.5
-
52
-
-
0020590028
-
HipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
-
Moyed, H. S. & Bertrand, K. P. hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J. Bacteriol. 155, 768-775 (1983).
-
(1983)
J. Bacteriol.
, vol.155
, pp. 768-775
-
-
Moyed, H.S.1
Bertrand, K.P.2
-
53
-
-
77957947243
-
Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis
-
Mulcahy, L. R., Burns, J. L., Lory, S. & Lewis, K. Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. J. Bacteriol. 192, 6191-6199 (2010).
-
(2010)
J. Bacteriol.
, vol.192
, pp. 6191-6199
-
-
Mulcahy, L.R.1
Burns, J.L.2
Lory, S.3
Lewis, K.4
-
54
-
-
84938812034
-
HipBA-promoter structures reveal the basis of heritable multidrug tolerance
-
Schumacher, M. A. et al. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature 524, 59-64 (2015).
-
(2015)
Nature
, vol.524
, pp. 59-64
-
-
Schumacher, M.A.1
-
55
-
-
73849102829
-
Patients with long-term oral carriage harbor high-persister mutants of Candida albicans
-
LaFleur, M. D., Qi, Q. & Lewis, K. Patients with long-term oral carriage harbor high-persister mutants of Candida albicans. Antimicrob. Agents Chemother. 54, 39-44 (2010).
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 39-44
-
-
LaFleur, M.D.1
Qi, Q.2
Lewis, K.3
-
56
-
-
84977156597
-
Elucidating population-wide mycobacterial replication dynamics at the single-cell level
-
Mouton, J. M., Helaine, S., Holden, D. W. & Sampson, S. L. Elucidating population-wide mycobacterial replication dynamics at the single-cell level. Microbiology 162, 966-978 (2016).
-
(2016)
Microbiology
, vol.162
, pp. 966-978
-
-
Mouton, J.M.1
Helaine, S.2
Holden, D.W.3
Sampson, S.L.4
-
57
-
-
0034002551
-
Dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms
-
Brooun, A., Liu, S. & Lewis, K. A. Dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob. Agents Chemother. 44, 640-646 (2000).
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 640-646
-
-
Brooun, A.1
Liu, S.2
Lewis, K.A.3
-
58
-
-
0035173818
-
Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials
-
Spoering, A. L. & Lewis, K. Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials. J. Bacteriol. 183, 6746-6751 (2001).
-
(2001)
J. Bacteriol.
, vol.183
, pp. 6746-6751
-
-
Spoering, A.L.1
Lewis, K.2
-
59
-
-
0346492817
-
Persister cells and tolerance to antimicrobials
-
Keren, I., Kaldalu, N., Spoering, A., Wang, Y. & Lewis, K. Persister cells and tolerance to antimicrobials. FEMS Microbiol. Lett. 230, 13-18 (2004).
-
(2004)
FEMS Microbiol. Lett.
, vol.230
, pp. 13-18
-
-
Keren, I.1
Kaldalu, N.2
Spoering, A.3
Wang, Y.4
Lewis, K.5
-
60
-
-
84883342218
-
(P) ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity
-
Maisonneuve, E., Castro-Camargo, M. & Gerdes, K. (p) ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 154, 1140-1150 (2013).
-
(2013)
Cell
, vol.154
, pp. 1140-1150
-
-
Maisonneuve, E.1
Castro-Camargo, M.2
Gerdes, K.3
-
61
-
-
84888019629
-
Activated ClpP kills persisters and eradicates a chronic biofilm infection
-
Conlon, B. P. et al. Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature 503, 365-370 (2013).
-
(2013)
Nature
, vol.503
, pp. 365-370
-
-
Conlon, B.P.1
-
62
-
-
77954651353
-
Biofilms in chronic infections - A matter of opportunity - Monospecies biofilms in multispecies infections
-
Burmølle, M. et al. Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunol. Med. Microbiol. 59, 324-336 (2010).
-
(2010)
FEMS Immunol. Med. Microbiol.
, vol.59
, pp. 324-336
-
-
Burmølle, M.1
-
63
-
-
77957961683
-
Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli
-
Hunstad, D. A. & Justice, S. S. Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli. Annu. Rev. Microbiol. 64, 203-221 (2010).
-
(2010)
Annu. Rev. Microbiol.
, vol.64
, pp. 203-221
-
-
Hunstad, D.A.1
Justice, S.S.2
-
64
-
-
0036431716
-
Pseudomonas aeruginosa in cystic fibrosis: Pathogenesis and persistence
-
Davies, J. C. Pseudomonas aeruginosa in cystic fibrosis: pathogenesis and persistence. Paediatr. Respir. Rev. 3, 128-134 (2002).
-
(2002)
Paediatr. Respir. Rev.
, vol.3
, pp. 128-134
-
-
Davies, J.C.1
-
65
-
-
17044395509
-
Intracellular Helicobacter pylori in gastric epithelial progenitors
-
Oh, J. D., Karam, S. M. & Gordon, J. I. Intracellular Helicobacter pylori in gastric epithelial progenitors. Proc. Natl Acad. Sci. USA 102, 5186-5191 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 5186-5191
-
-
Oh, J.D.1
Karam, S.M.2
Gordon, J.I.3
-
66
-
-
84863315894
-
Review article: Biofilm formation by Helicobacter pylori as a target for eradication of resistant infection
-
Cammarota, G., Sanguinetti, M., Gallo, A. & Posteraro, B. Review article: biofilm formation by Helicobacter pylori as a target for eradication of resistant infection. Aliment. Pharmacol. Ther. 36, 222-230 (2012).
-
(2012)
Aliment. Pharmacol. Ther.
, vol.36
, pp. 222-230
-
-
Cammarota, G.1
Sanguinetti, M.2
Gallo, A.3
Posteraro, B.4
-
67
-
-
0036117936
-
Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp
-
Prouty, A. M., Schwesinger, W. H. & Gunn, J. S. Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp. Infect. Immun. 70, 2640-2649 (2002).
-
(2002)
Infect. Immun.
, vol.70
, pp. 2640-2649
-
-
Prouty, A.M.1
Schwesinger, W.H.2
Gunn, J.S.3
-
68
-
-
84878204775
-
Metabolic control of persister formation in Escherichia coli
-
Amato, S. M., Orman, M. A. & Brynildsen, M. P. Metabolic control of persister formation in Escherichia coli. Mol. Cell 50, 475-487 (2013).
-
(2013)
Mol. Cell
, vol.50
, pp. 475-487
-
-
Amato, S.M.1
Orman, M.A.2
Brynildsen, M.P.3
-
69
-
-
77649174212
-
Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli
-
Dörr, T., Vulić, M. & Lewis, K. Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. PLoS Biol. 8, e1000317 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000317
-
-
Dörr, T.1
Vulić, M.2
Lewis, K.3
-
70
-
-
84879728880
-
Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
-
Fasani, R. A. & Savageau, M. A. Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype. Proc. Natl Acad. Sci. USA 110, E2528-E2537 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. E2528-E2537
-
-
Fasani, R.A.1
Savageau, M.A.2
-
71
-
-
81555212273
-
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria
-
Nguyen, D. et al. Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science 334, 982-986 (2011).
-
(2011)
Science
, vol.334
, pp. 982-986
-
-
Nguyen, D.1
-
72
-
-
0020804285
-
Mini-F plasmid genes that couple host cell division to plasmid proliferation
-
Ogura, T. & Hiraga, S. Mini-F plasmid genes that couple host cell division to plasmid proliferation. Proc. Natl Acad. Sci. USA 80, 4784-4788 (1983).
-
(1983)
Proc. Natl Acad. Sci. USA
, vol.80
, pp. 4784-4788
-
-
Ogura, T.1
Hiraga, S.2
-
73
-
-
0345333119
-
Unique type of plasmid maintenance function: Postsegregational killing of plasmid-free cells
-
Gerdes, K., Rasmussen, P. B. & Molin, S. Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells. Proc. Natl Acad. Sci. USA 83, 3116-3120 (1986).
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 3116-3120
-
-
Gerdes, K.1
Rasmussen, P.B.2
Molin, S.3
-
74
-
-
14244266086
-
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes
-
Pandey, D. P. & Gerdes, K. Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res. 33, 966-976 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 966-976
-
-
Pandey, D.P.1
Gerdes, K.2
-
75
-
-
17844370503
-
Prokaryotic toxin-antitoxin stress response loci
-
Gerdes, K., Christensen, S. K. & Lobner-Olesen, A. Prokaryotic toxin-antitoxin stress response loci. Nat. Rev. Microbiol. 3, 371-382 (2005).
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 371-382
-
-
Gerdes, K.1
Christensen, S.K.2
Lobner-Olesen, A.3
-
76
-
-
80054759036
-
Regulation of growth and death in Escherichia coli by toxin-antitoxin systems
-
Yamaguchi, Y. & Inouye, M. Regulation of growth and death in Escherichia coli by toxin-antitoxin systems. Nat. Rev. Microbiol. 9, 779-790 (2011).
-
(2011)
Nat. Rev. Microbiol.
, vol.9
, pp. 779-790
-
-
Yamaguchi, Y.1
Inouye, M.2
-
77
-
-
77955452979
-
Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence
-
Rotem, E. et al. Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence. Proc. Natl Acad. Sci. USA 107, 12541-12546 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 12541-12546
-
-
Rotem, E.1
-
78
-
-
84864950352
-
Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery
-
Cataudella, I., Trusina, A., Sneppen, K., Gerdes, K. & Mitarai, N. Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery. Nucleic Acids Res. 40, 6424-6434 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 6424-6434
-
-
Cataudella, I.1
Trusina, A.2
Sneppen, K.3
Gerdes, K.4
Mitarai, N.5
-
79
-
-
84962495845
-
Toxin-antitoxin systems in bacterial growth arrest and persistence
-
Page, R. & Peti, W. Toxin-antitoxin systems in bacterial growth arrest and persistence. Nat. Chem. Biol. 12, 208-214 (2016).
-
(2016)
Nat. Chem. Biol.
, vol.12
, pp. 208-214
-
-
Page, R.1
Peti, W.2
-
80
-
-
10044266575
-
Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
-
Keren, I., Shah, D., Spoering, A., Kaldalu, N. & Lewis, K. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J. Bacteriol. 186, 8172-8180 (2004).
-
(2004)
J. Bacteriol.
, vol.186
, pp. 8172-8180
-
-
Keren, I.1
Shah, D.2
Spoering, A.3
Kaldalu, N.4
Lewis, K.5
-
81
-
-
33747436591
-
Persisters: A distinct physiological state of E. Coli
-
Shah, D. et al. Persisters: a distinct physiological state of E. coli. BMC Microbiol. 6, 53 (2006).
-
(2006)
BMC Microbiol.
, vol.6
, pp. 53
-
-
Shah, D.1
-
82
-
-
80052016172
-
Bacterial persistence by RNA endonucleases
-
Maisonneuve, E., Shakespeare, L. J., Jørgensen, M. G. & Gerdes, K. Bacterial persistence by RNA endonucleases. Proc. Natl Acad. Sci. USA 108, 13206-13211 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 13206-13211
-
-
Maisonneuve, E.1
Shakespeare, L.J.2
Jørgensen, M.G.3
Gerdes, K.4
-
83
-
-
84937119399
-
Obg and membrane depolarization are part of a microbial bet-hedging strategy that leads to antibiotic tolerance
-
Verstraeten, N. et al. Obg and membrane depolarization are part of a microbial bet-hedging strategy that leads to antibiotic tolerance. Mol. Cell 59, 9-21 (2015).
-
(2015)
Mol. Cell
, vol.59
, pp. 9-21
-
-
Verstraeten, N.1
-
84
-
-
0026601663
-
Proteases and protein degradation in Escherichia coli
-
Maurizi, M. R. Proteases and protein degradation in Escherichia coli. Experientia 48, 178-201 (1992).
-
(1992)
Experientia
, vol.48
, pp. 178-201
-
-
Maurizi, M.R.1
-
85
-
-
84891136247
-
Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis
-
Kint, C., Verstraeten, N., Hofkens, J., Fauvart, M. & Michiels, J. Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis. Crit. Rev. Microbiol. 40, 207-224 (2014).
-
(2014)
Crit. Rev. Microbiol.
, vol.40
, pp. 207-224
-
-
Kint, C.1
Verstraeten, N.2
Hofkens, J.3
Fauvart, M.4
Michiels, J.5
-
86
-
-
84888991522
-
Tolerance of Escherichia coli to fluoroquinolone antibiotics depends on specific components of the SOS response pathway
-
Theodore, A., Lewis, K. & Vulić, M. Tolerance of Escherichia coli to fluoroquinolone antibiotics depends on specific components of the SOS response pathway. Genetics 195, 1265-1276 (2013).
-
(2013)
Genetics
, vol.195
, pp. 1265-1276
-
-
Theodore, A.1
Lewis, K.2
Vulić, M.3
-
87
-
-
84929467281
-
Genetic basis of persister tolerance to aminoglycosides in Escherichia coli
-
Shan, Y., Lazinski, D., Rowe, S., Camilli, A. & Lewis, K. Genetic basis of persister tolerance to aminoglycosides in Escherichia coli. mBio 6, e00078-15 (2015).
-
(2015)
MBio
, vol.6
, pp. e00078-e000715
-
-
Shan, Y.1
Lazinski, D.2
Rowe, S.3
Camilli, A.4
Lewis, K.5
-
88
-
-
0020651799
-
Protein degradation in Escherichia coli: The lon gene controls the stability of SulA protein
-
Mizusawa, S. & Gottesman, S. Protein degradation in Escherichia coli: the lon gene controls the stability of SulA protein. Proc. Natl Acad. Sci. USA 80, 358-362 (1983).
-
(1983)
Proc. Natl Acad. Sci. USA
, vol.80
, pp. 358-362
-
-
Mizusawa, S.1
Gottesman, S.2
-
89
-
-
84886290812
-
Molecular mechanism of bacterial persistence by HipA
-
Germain, E., Castro-Roa, D., Zenkin, N. & Gerdes, K. Molecular mechanism of bacterial persistence by HipA. Mol. Cell 52, 248-254 (2013).
-
(2013)
Mol. Cell
, vol.52
, pp. 248-254
-
-
Germain, E.1
Castro-Roa, D.2
Zenkin, N.3
Gerdes, K.4
-
90
-
-
0037428226
-
The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site
-
Pedersen, K. et al. The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell 112, 131-140 (2003).
-
(2003)
Cell
, vol.112
, pp. 131-140
-
-
Pedersen, K.1
-
91
-
-
0038797797
-
RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA
-
Christensen, S. K. & Gerdes, K. RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA. Mol. Microbiol. 48, 1389-1400 (2003).
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 1389-1400
-
-
Christensen, S.K.1
Gerdes, K.2
-
92
-
-
74349123303
-
Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses
-
Christensen-Dalsgaard, M., Jørgensen, M. G. & Gerdes, K. Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol. Microbiol. 75, 333-348 (2010).
-
(2010)
Mol. Microbiol.
, vol.75
, pp. 333-348
-
-
Christensen-Dalsgaard, M.1
Jørgensen, M.G.2
Gerdes, K.3
-
93
-
-
79956328889
-
Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA
-
Winther, K. S. & Gerdes, K. Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA. Proc. Natl Acad. Sci. USA 108, 7403-7407 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7403-7407
-
-
Winther, K.S.1
Gerdes, K.2
-
94
-
-
85006259960
-
VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation
-
Winther, K., Tree, J. J., Tollervey, D. & Gerdes, K. VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation. Nucleic Acids Res. 9860-9871 (2016).
-
(2016)
Nucleic Acids Res.
, pp. 9860-9871
-
-
Winther, K.1
Tree, J.J.2
Tollervey, D.3
Gerdes, K.4
-
95
-
-
84887997250
-
The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu
-
Castro-Roa, D. et al. The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu. Nat. Chem. Biol. 9, 811-817 (2013).
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 811-817
-
-
Castro-Roa, D.1
-
96
-
-
0027142978
-
The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase
-
Bernard, P. et al. The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase. J. Mol. Biol. 234, 534-541 (1993).
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 534-541
-
-
Bernard, P.1
-
97
-
-
0036098378
-
ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase
-
Jiang, Y., Pogliano, J., Helinski, D. R. & Konieczny, I. ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase. Mol. Microbiol. 44, 971-979 (2002).
-
(2002)
Mol. Microbiol.
, vol.44
, pp. 971-979
-
-
Jiang, Y.1
Pogliano, J.2
Helinski, D.R.3
Konieczny, I.4
-
98
-
-
84940787947
-
Adenylylation of gyrase and Topo IV by FicT toxins disrupts bacterial DNA topology
-
Harms, A. et al. Adenylylation of gyrase and Topo IV by FicT toxins disrupts bacterial DNA topology. Cell Rep. 12, 1497-1507 (2015).
-
(2015)
Cell Rep.
, vol.12
, pp. 1497-1507
-
-
Harms, A.1
-
99
-
-
84976509923
-
A Salmonella toxin promotes persister formation through acetylation of tRNA
-
Cheverton, A. M. et al. A Salmonella toxin promotes persister formation through acetylation of tRNA. Mol. Cell 63, 86-96 (2016).
-
(2016)
Mol. Cell
, vol.63
, pp. 86-96
-
-
Cheverton, A.M.1
-
100
-
-
0036067108
-
Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
-
Pedersen, K., Christensen, S. K. & Gerdes, K. Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol. Microbiol. 45, 501-510 (2002).
-
(2002)
Mol. Microbiol.
, vol.45
, pp. 501-510
-
-
Pedersen, K.1
Christensen, S.K.2
Gerdes, K.3
-
101
-
-
67049145664
-
The chromosomal toxin gene yafQ is a determinant of multidrug tolerance for Escherichia coli growing in a biofilm
-
Harrison, J. J. et al. The chromosomal toxin gene yafQ is a determinant of multidrug tolerance for Escherichia coli growing in a biofilm. Antimicrob. Agents Chemother. 53, 2253-2258 (2009).
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2253-2258
-
-
Harrison, J.J.1
-
102
-
-
84925235038
-
Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells
-
Lobato-Márquez, D., Moreno-Córdoba, I., Figueroa, V., Díaz-Orejas, R. & García-del Portillo, F. Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells. Sci. Rep. 5, 9374 (2015).
-
(2015)
Sci. Rep.
, vol.5
, pp. 9374
-
-
Lobato-Márquez, D.1
Moreno-Córdoba, I.2
Figueroa, V.3
Díaz-Orejas, R.4
García-Del Portillo, F.5
-
103
-
-
84890639139
-
HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase
-
Kaspy, I. et al. HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase. Nat. Commun. 4, 3001 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 3001
-
-
Kaspy, I.1
-
104
-
-
84928326779
-
Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases
-
Germain, E., Roghanian, M., Gerdes, K. & Maisonneuve, E. Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases. Proc. Natl Acad. Sci. USA 112, 5171-5176 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 5171-5176
-
-
Germain, E.1
Roghanian, M.2
Gerdes, K.3
Maisonneuve, E.4
-
105
-
-
84978122872
-
Persister formation in Staphylococcus aureus is associated with ATP depletion
-
Conlon, B. P. et al. Persister formation in Staphylococcus aureus is associated with ATP depletion. Nat. Microbiol. 1, 16051 (2016).
-
(2016)
Nat. Microbiol.
, vol.1
, pp. 16051
-
-
Conlon, B.P.1
-
106
-
-
64049118002
-
Overexpression of MazFSa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage
-
Fu, Z., Tamber, S., Memmi, G., Donegan, N. P. & Cheung, A. L. Overexpression of MazFSa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage. J. Bacteriol. 191, 2051-2059 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 2051-2059
-
-
Fu, Z.1
Tamber, S.2
Memmi, G.3
Donegan, N.P.4
Cheung, A.L.5
-
107
-
-
65249145128
-
Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression
-
Donegan, N. P. & Cheung, A. L. Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression. J. Bacteriol. 191, 2795-2805 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 2795-2805
-
-
Donegan, N.P.1
Cheung, A.L.2
-
108
-
-
84957572395
-
Persistence increases in the absence of the alarmone guanosine tetraphosphate by reducing cell growth
-
Chowdhury, N., Kwan, B. W. & Wood, T. K. Persistence increases in the absence of the alarmone guanosine tetraphosphate by reducing cell growth. Sci. Rep. 6, 20519 (2016).
-
(2016)
Sci. Rep.
, vol.6
, pp. 20519
-
-
Chowdhury, N.1
Kwan, B.W.2
Wood, T.K.3
-
109
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. http://dx.doi.org/10.1038/ msb4100050 (2006).
-
(2006)
Mol. Syst. Biol.
-
-
Baba, T.1
-
110
-
-
48749089081
-
Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli
-
Hansen, S., Lewis, K. & Vulić, M. Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrob. Agents Chemother. 52, 2718-2726 (2008).
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 2718-2726
-
-
Hansen, S.1
Lewis, K.2
Vulić, M.3
-
111
-
-
85015004959
-
Bacterial persistence from a system-level perspective
-
Radzikowski, J. L., Schramke, H. & Heinemann, M. Bacterial persistence from a system-level perspective. Curr. Opin. Biotechnol. 46, 98-105 (2017).
-
(2017)
Curr. Opin. Biotechnol.
, vol.46
, pp. 98-105
-
-
Radzikowski, J.L.1
Schramke, H.2
Heinemann, M.3
-
112
-
-
84988923014
-
Bacterial persistence is an active σs stress response to metabolic flux limitation
-
Radzikowski, J. L. et al. Bacterial persistence is an active σS stress response to metabolic flux limitation. Mol. Syst. Biol. 12, 882 (2016).
-
(2016)
Mol. Syst. Biol.
, vol.12
, pp. 882
-
-
Radzikowski, J.L.1
-
113
-
-
84939525294
-
Persister heterogeneity arising from a single metabolic stress
-
Amato, S. M. & Brynildsen, M. P. Persister heterogeneity arising from a single metabolic stress. Curr. Biol. 25, 2090-2098 (2015).
-
(2015)
Curr. Biol.
, vol.25
, pp. 2090-2098
-
-
Amato, S.M.1
Brynildsen, M.P.2
-
114
-
-
85014743203
-
ATP-dependent persister formation in Escherichia coli
-
Shan, Y. et al. ATP-dependent persister formation in Escherichia coli. mBio 8, e02267-16 (2017).
-
(2017)
MBio
, vol.8
, pp. e02267-e02316
-
-
Shan, Y.1
-
115
-
-
84963864703
-
Enhanced efflux activity facilitates drug tolerance in dormant bacterial cells
-
Pu, Y. et al. Enhanced efflux activity facilitates drug tolerance in dormant bacterial cells. Mol. Cell 62, 284-294 (2016).
-
(2016)
Mol. Cell
, vol.62
, pp. 284-294
-
-
Pu, Y.1
-
116
-
-
84974518472
-
Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae
-
Band, V. I. et al. Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae. Nat. Microbiol. 1, 16053 (2016).
-
(2016)
Nat. Microbiol.
, vol.1
, pp. 16053
-
-
Band, V.I.1
-
117
-
-
84992378393
-
Staphylococcus aureus inactivates daptomycin by releasing membrane phospholipids
-
Pader, V. et al. Staphylococcus aureus inactivates daptomycin by releasing membrane phospholipids. Nat. Microbiol. 2, 16194 (2016).
-
(2016)
Nat. Microbiol.
, vol.2
, pp. 16194
-
-
Pader, V.1
-
118
-
-
53349128304
-
RNAIII-independent target gene control by the agr quorum-sensing system: Insight into the evolution of virulence regulation in Staphylococcus aureus
-
Queck, S. Y. et al. RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol. Cell 32, 150-158 (2008).
-
(2008)
Mol. Cell
, vol.32
, pp. 150-158
-
-
Queck, S.Y.1
-
119
-
-
84922789867
-
What role does the quorum-sensing accessory gene regulator system play during Staphylococcus aureus bacteremia?
-
Painter, K. L., Krishna, A., Wigneshweraraj, S. & Edwards, A. M. What role does the quorum-sensing accessory gene regulator system play during Staphylococcus aureus bacteremia? Trends Microbiol. 22, 676-685 (2014).
-
(2014)
Trends Microbiol.
, vol.22
, pp. 676-685
-
-
Painter, K.L.1
Krishna, A.2
Wigneshweraraj, S.3
Edwards, A.M.4
-
120
-
-
47749089764
-
Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity
-
Overgaard, M., Borch, J., Jørgensen, M. G. & Gerdes, K. Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity. Mol. Microbiol. 69, 841-857 (2008).
-
(2008)
Mol. Microbiol.
, vol.69
, pp. 841-857
-
-
Overgaard, M.1
Borch, J.2
Jørgensen, M.G.3
Gerdes, K.4
-
121
-
-
85014452658
-
Toxin-antitoxin systems: Reversible toxicity
-
Hall, A. M. J., Gollan, B. & Helaine, S. Toxin-antitoxin systems: reversible toxicity. Curr. Opin. Microbiol. 36, 102-110 (2017).
-
(2017)
Curr. Opin. Microbiol.
, vol.36
, pp. 102-110
-
-
Hall, A.M.J.1
Gollan, B.2
Helaine, S.3
-
122
-
-
0041825422
-
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA
-
Christensen, S. K., Pedersen, K., Hansen, F. G. & Gerdes, K. Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J. Mol. Biol. 332, 809-819 (2003).
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 809-819
-
-
Christensen, S.K.1
Pedersen, K.2
Hansen, F.G.3
Gerdes, K.4
-
123
-
-
79955886933
-
Metabolite-enabled eradication of bacterial persisters by aminoglycosides
-
Allison, K. R., Brynildsen, M. P. & Collins, J. J. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 473, 216-220 (2011).
-
(2011)
Nature
, vol.473
, pp. 216-220
-
-
Allison, K.R.1
Brynildsen, M.P.2
Collins, J.J.3
-
124
-
-
84866685714
-
Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one
-
Pan, J., Bahar, A. A., Syed, H. & Ren, D. Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one. PLoS ONE 7, e45778 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e45778
-
-
Pan, J.1
Bahar, A.A.2
Syed, H.3
Ren, D.4
-
125
-
-
77953274576
-
How tumour necrosis factor blockers interfere with tuberculosis immunity
-
Harris, J. & Keane, J. How tumour necrosis factor blockers interfere with tuberculosis immunity. Clin. Exp. Immunol. 161, 1-9 (2010).
-
(2010)
Clin. Exp. Immunol.
, vol.161
, pp. 1-9
-
-
Harris, J.1
Keane, J.2
-
126
-
-
0346734115
-
Transcriptome analysis of chlamydial growth during IFNγ-mediated persistence and reactivation
-
Belland, R. J. et al. Transcriptome analysis of chlamydial growth during IFNγ-mediated persistence and reactivation. Proc. Natl Acad. Sci. USA 100, 15971-15976 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15971-15976
-
-
Belland, R.J.1
-
127
-
-
0142062024
-
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli
-
Layton, J. C. & Foster, P. L. Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Mol. Microbiol. 50, 549-561 (2003).
-
(2003)
Mol. Microbiol.
, vol.50
, pp. 549-561
-
-
Layton, J.C.1
Foster, P.L.2
-
128
-
-
0035997344
-
Error-prone repair DNA polymerases in prokaryotes and eukaryotes
-
Goodman, M. F. Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Annu. Rev. Biochem. 71, 17-50 (2002).
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 17-50
-
-
Goodman, M.F.1
-
129
-
-
74249107300
-
SOS response induces persistence to fluoroquinolones in Escherichia coli
-
Dörr, T., Lewis, K. & Vulić, M. SOS response induces persistence to fluoroquinolones in Escherichia coli. PLOS Genet. 5, e1000760 (2009).
-
(2009)
PLOS Genet.
, vol.5
, pp. e1000760
-
-
Dörr, T.1
Lewis, K.2
Vulić, M.3
-
130
-
-
0345827436
-
SOS response promotes horizontal dissemination of antibiotic resistance genes
-
Beaber, J. W., Hochhut, B. & Waldor, M. K. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427, 72-74 (2004).
-
(2004)
Nature
, vol.427
, pp. 72-74
-
-
Beaber, J.W.1
Hochhut, B.2
Waldor, M.K.3
-
131
-
-
84946600316
-
Stationary-phase persisters to ofloxacin sustain DNA damage and require repair systems only during recovery
-
Völzing, K. G. & Brynildsen, M. P. Stationary-phase persisters to ofloxacin sustain DNA damage and require repair systems only during recovery. mBio 6, e00731-15 (2015).
-
(2015)
MBio
, vol.6
, pp. e00731-e00815
-
-
Völzing, K.G.1
Brynildsen, M.P.2
-
132
-
-
84995390385
-
Persistence to anti-cancer treatments in the stationary to proliferating transition
-
Pearl Mizrahi, S., Gefen, O., Simon, I. & Balaban, N. Q. Persistence to anti-cancer treatments in the stationary to proliferating transition. Cell Cycle 15, 3442-3453 (2016).
-
(2016)
Cell Cycle
, vol.15
, pp. 3442-3453
-
-
Pearl Mizrahi, S.1
Gefen, O.2
Simon, I.3
Balaban, N.Q.4
-
134
-
-
77649267953
-
Dynamics of intracellular bacterial replication at the single cell level
-
Helaine, S. et al. Dynamics of intracellular bacterial replication at the single cell level. Proc. Natl Acad. Sci. USA 107, 3746-3751 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 3746-3751
-
-
Helaine, S.1
-
135
-
-
84920880232
-
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms
-
Manina, G., Dhar, N. & McKinney, J. D. Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms. Cell Host Microbe 17, 32-46 (2015).
-
(2015)
Cell Host Microbe
, vol.17
, pp. 32-46
-
-
Manina, G.1
Dhar, N.2
McKinney, J.D.3
-
136
-
-
57749195712
-
RNA-Seq: A revolutionary tool for transcriptomics
-
Wang, Z., Gerstein, M. & Snyder, M. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 10, 57-63 (2009).
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 57-63
-
-
Wang, Z.1
Gerstein, M.2
Snyder, M.3
-
137
-
-
77956342535
-
Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes
-
Levin-Reisman, I. et al. Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes. Nat. Methods 7, 737-739 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 737-739
-
-
Levin-Reisman, I.1
-
138
-
-
84864281978
-
Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers
-
Gurnev, P. A., Ortenberg, R., Dörr, T., Lewis, K. & Bezrukov, S. M. Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers. FEBS Lett. 586, 2529-2534 (2012).
-
(2012)
FEBS Lett.
, vol.586
, pp. 2529-2534
-
-
Gurnev, P.A.1
Ortenberg, R.2
Dörr, T.3
Lewis, K.4
Bezrukov, S.M.5
-
139
-
-
78650293305
-
Targeting bacterial membrane function: An underexploited mechanism for treating persistent infections
-
Hurdle, J. G., O'Neill, A. J., Chopra, I. & Lee, R. E. Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections. Nat. Rev. Microbiol. 9, 62-75 (2011).
-
(2011)
Nat. Rev. Microbiol.
, vol.9
, pp. 62-75
-
-
Hurdle, J.G.1
O'Neill, A.J.2
Chopra, I.3
Lee, R.E.4
-
140
-
-
79961095617
-
Control of bacterial persister cells by Trp/Arg-containing antimicrobial peptides
-
Chen, X., Zhang, M., Zhou, C., Kallenbach, N. R. & Ren, D. Control of bacterial persister cells by Trp/Arg-containing antimicrobial peptides. Appl. Environ. Microbiol. 77, 4878-4885 (2011).
-
(2011)
Appl. Environ. Microbiol.
, vol.77
, pp. 4878-4885
-
-
Chen, X.1
Zhang, M.2
Zhou, C.3
Kallenbach, N.R.4
Ren, D.5
-
141
-
-
84970027631
-
Membrane-targeting AM-0016 kills mycobacterial persisters and shows low propensity for resistance development
-
Mukherjee, D., Zou, H., Liu, S., Beuerman, R. & Dick, T. Membrane-targeting AM-0016 kills mycobacterial persisters and shows low propensity for resistance development. Future Microbiol. 11, 643-650 (2016).
-
(2016)
Future Microbiol.
, vol.11
, pp. 643-650
-
-
Mukherjee, D.1
Zou, H.2
Liu, S.3
Beuerman, R.4
Dick, T.5
-
142
-
-
84960111425
-
NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption
-
Kim, W. et al. NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption. Future Med. Chem. 8, 257-269 (2016).
-
(2016)
Future Med. Chem.
, vol.8
, pp. 257-269
-
-
Kim, W.1
-
143
-
-
84925590102
-
Engineering persister-specific antibiotics with synergistic antimicrobial functions
-
Schmidt, N. W. et al. Engineering persister-specific antibiotics with synergistic antimicrobial functions. ACS Nano 8, 8786-8793 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 8786-8793
-
-
Schmidt, N.W.1
-
144
-
-
84947751820
-
Novel antibody-antibiotic conjugate eliminates intracellular S. Aureus
-
Lehar, S. M. et al. Novel antibody-antibiotic conjugate eliminates intracellular S. aureus. Nature 527, 323-328 (2015).
-
(2015)
Nature
, vol.527
, pp. 323-328
-
-
Lehar, S.M.1
-
145
-
-
84987849551
-
Engineered bacteriophage lysins as novel anti-infectives
-
Yang, H., Yu, J. & Wei, H. Engineered bacteriophage lysins as novel anti-infectives. Front. Microbiol. 5, 542 (2014).
-
(2014)
Front. Microbiol.
, vol.5
, pp. 542
-
-
Yang, H.1
Yu, J.2
Wei, H.3
-
146
-
-
84903206252
-
Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa
-
Briers, Y. et al. Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 58, 3774-3784 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 3774-3784
-
-
Briers, Y.1
-
147
-
-
78649327706
-
Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: A single-center experience
-
De Soyza, A. et al. Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: a single-center experience. J. Heart Lung Transplant. 29, 1395-1404 (2010).
-
(2010)
J. Heart Lung Transplant.
, vol.29
, pp. 1395-1404
-
-
De Soyza, A.1
-
148
-
-
84887458051
-
Haemophilus influenzae and the lung (Haemophilus and the lung)
-
King, P. Haemophilus influenzae and the lung (Haemophilus and the lung). Clin. Transl Med. 1, 10 (2012).
-
(2012)
Clin. Transl Med.
, vol.1
, pp. 10
-
-
King, P.1
-
149
-
-
0037414066
-
Intracellular survival of Brucella: Defining the link with persistence
-
Ficht, T. A. Intracellular survival of Brucella: defining the link with persistence. Vet. Microbiol. 92, 213-223 (2003).
-
(2003)
Vet. Microbiol.
, vol.92
, pp. 213-223
-
-
Ficht, T.A.1
-
150
-
-
65449136250
-
Diagnosis and treatment of acute or persistent diarrhea
-
Pawlowski, S. W., Warren, C. A. & Guerrant, R. Diagnosis and treatment of acute or persistent diarrhea. Gastroenterology 136, 1874-1886 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 1874-1886
-
-
Pawlowski, S.W.1
Warren, C.A.2
Guerrant, R.3
-
151
-
-
80052719520
-
Best strategies in recurrent or persistent Clostridium difficile infection
-
Cocanour, C. S. Best strategies in recurrent or persistent Clostridium difficile infection. Surg. Infect. (Larchmt) 12, 235-239 (2011).
-
(2011)
Surg. Infect. (Larchmt)
, vol.12
, pp. 235-239
-
-
Cocanour, C.S.1
-
152
-
-
84963949141
-
Persistent infections by nontyphoidal Salmonella in humans: Epidemiology and genetics
-
Marzel, A. et al. Persistent infections by nontyphoidal Salmonella in humans: epidemiology and genetics. Clin. Infect. Dis. 62, 879-886 (2016).
-
(2016)
Clin. Infect. Dis.
, vol.62
, pp. 879-886
-
-
Marzel, A.1
-
153
-
-
84874936592
-
Persistent Staphylococcus aureus bacteremia: A prospective analysis of risk factors, outcomes, and microbiologic and genotypic characteristics of isolates
-
Chong, Y. P. et al. Persistent Staphylococcus aureus bacteremia: a prospective analysis of risk factors, outcomes, and microbiologic and genotypic characteristics of isolates. Medicine (Baltimore) 92, 98-108 (2013).
-
(2013)
Medicine (Baltimore)
, vol.92
, pp. 98-108
-
-
Chong, Y.P.1
-
154
-
-
84964240913
-
Chlamydia cell biology and pathogenesis
-
Elwell, C., Mirrashidi, K. & Engel, J. Chlamydia cell biology and pathogenesis. Nat. Rev. Microbiol. 14, 385-400 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 385-400
-
-
Elwell, C.1
Mirrashidi, K.2
Engel, J.3
-
155
-
-
84990911171
-
Treponema pallidum, the syphilis spirochete: Making a living as a stealth pathogen
-
Radolf, J. D. et al. Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen. Nat. Rev. Microbiol. 14, 744-759 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 744-759
-
-
Radolf, J.D.1
|