-
1
-
-
81955167411
-
Persistence: Mechanisms for triggering and enhancing phenotypic variability
-
Balaban, N. Q. Persistence: mechanisms for triggering and enhancing phenotypic variability. Curr. Opin. Genet. Dev. 21, 768-775 (2011).
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 768-775
-
-
Balaban, N.Q.1
-
2
-
-
77955628762
-
Persister cells
-
Lewis, K. Persister cells. Annu. Rev. Microbiol. 64, 357-372 (2010).
-
(2010)
Annu. Rev. Microbiol.
, vol.64
, pp. 357-372
-
-
Lewis, K.1
-
3
-
-
50349141358
-
Treatment of staphylococcal infections with penicillin by intermittent sterilisation
-
Bigger, J. Treatment of staphylococcal infections with penicillin by intermittent sterilisation. Lancet 244, 497-500 (1944).
-
(1944)
Lancet
, vol.244
, pp. 497-500
-
-
Bigger, J.1
-
4
-
-
10044266575
-
Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
-
DOI 10.1128/JB.186.24.8172-8180.2004
-
Keren, I., Shah, D., Spoering, A., Kaldalu, N. & Lewis, K. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J. Bacteriol. 186, 8172-8180 (2004). (Pubitemid 39603206)
-
(2004)
Journal of Bacteriology
, vol.186
, Issue.24
, pp. 8172-8180
-
-
Keren, I.1
Shah, D.2
Spoering, A.3
Kaldalu, N.4
Lewis, K.5
-
5
-
-
45149086183
-
Nongenetic individuality in the host-phage interaction
-
Pearl, S., Gabay, C., Kishony, R., Oppenheim, A. & Balaban, N. Q. Nongenetic individuality in the host-phage interaction. PLoS Biol. 6, e120 (2008).
-
(2008)
PLoS Biol.
, vol.6
-
-
Pearl, S.1
Gabay, C.2
Kishony, R.3
Oppenheim, A.4
Balaban, N.Q.5
-
6
-
-
0023804926
-
Conditional impairment of cell division and altered lethality in hipA mutants of Escherichia coli K-12
-
Scherrer, R. & Moyed, H. S. Conditional impairment of cell division and altered lethality in hipA mutants of Escherichia coli K-12. J. Bacteriol. 170, 3321-3326 (1988).
-
(1988)
J. Bacteriol.
, vol.170
, pp. 3321-3326
-
-
Scherrer, R.1
Moyed, H.S.2
-
7
-
-
80052016172
-
Bacterial persistence by RNA endonucleases
-
Maisonneuve, E., Shakespeare, L. J., Jorgensen, M. G. & Gerdes, K. Bacterial persistence by RNA endonucleases. Proc. Natl Acad. Sci. USA 108, 13206-13211 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 13206-13211
-
-
Maisonneuve, E.1
Shakespeare, L.J.2
Jorgensen, M.G.3
Gerdes, K.4
-
8
-
-
80053474881
-
Toxins-antitoxins: Diversity, evolution and function
-
Hayes, F. & Van Melderen, L. Toxins-antitoxins: diversity, evolution and function. Crit. Rev. Biochem. Mol. Biol. 46, 386-408 (2011).
-
(2011)
Crit. Rev. Biochem. Mol. Biol.
, vol.46
, pp. 386-408
-
-
Hayes, F.1
Van Melderen, L.2
-
9
-
-
0020590028
-
HipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
-
Moyed, H. S. & Bertrand, K. P. HipA, A newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J. Bacteriol. 155, 768-775 (1983). (Pubitemid 13048115)
-
(1983)
Journal of Bacteriology
, vol.155
, Issue.2
, pp. 768-775
-
-
Moyed, H.S.1
Bertrand, K.P.2
-
10
-
-
33845428404
-
Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli
-
DOI 10.1128/JB.01237-06
-
Correia, F. F. et al. Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli. J. Bacteriol. 188, 8360-8367 (2006). (Pubitemid 44894035)
-
(2006)
Journal of Bacteriology
, vol.188
, Issue.24
, pp. 8360-8367
-
-
Correia, F.F.1
D'Onofrio, A.2
Rejtar, T.3
Li, L.4
Karger, B.L.5
Makarova, K.6
Koonin, E.V.7
Lewis, K.8
-
11
-
-
58449087611
-
Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB
-
Schumacher, M. A. et al. Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science 323, 396-401 (2009).
-
(2009)
Science
, vol.323
, pp. 396-401
-
-
Schumacher, M.A.1
-
12
-
-
33744729683
-
Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: Effects on macromolecular synthesis and persister formation
-
DOI 10.1128/JB.01740-05
-
Korch, S. B. & Hill, T. M. Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formation. J. Bacteriol. 188, 3826-3836 (2006). (Pubitemid 43825388)
-
(2006)
Journal of Bacteriology
, vol.188
, Issue.11
, pp. 3826-3836
-
-
Korch, S.B.1
Hill, T.M.2
-
13
-
-
77955452979
-
Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence
-
Rotem, E. et al. Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence. Proc. Natl Acad. Sci. USA 107, 12541-12546 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 12541-12546
-
-
Rotem, E.1
-
14
-
-
0344826574
-
Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis
-
DOI 10.1046/j.1365-2958.2003.03779.x
-
Korch, S. B., Henderson, T. A. & Hill, T. M. Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis. Mol. Microbiol. 50, 1199-1213 (2003). (Pubitemid 37475853)
-
(2003)
Molecular Microbiology
, vol.50
, Issue.4
, pp. 1199-1213
-
-
Korch, S.B.1
Henderson, T.A.2
Hill, T.M.3
-
15
-
-
81555212273
-
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria
-
Nguyen, D. et al. Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science 334, 982-986 (2011).
-
(2011)
Science
, vol.334
, pp. 982-986
-
-
Nguyen, D.1
-
16
-
-
84878204775
-
Metabolic control of persister formation in Escherichia coli
-
Amato, S. M., Orman, M. A. & Brynildsen, M. P. Metabolic control of persister formation in Escherichia coli. Mol. Cell 50, 475-487 (2013).
-
(2013)
Mol. Cell
, vol.50
, pp. 475-487
-
-
Amato, S.M.1
Orman, M.A.2
Brynildsen, M.P.3
-
17
-
-
84883342218
-
PpGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity
-
Maisonneuve, E., Castro-Camargo, M. & Gerdes, K. (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 154, 1140-1150 (2013).
-
(2013)
Cell
, vol.154
, pp. 1140-1150
-
-
Maisonneuve, E.1
Castro-Camargo, M.2
-
18
-
-
84880027587
-
HipA-triggered growth arrest and beta-lactam tolerance in Escherichia coli is mediated by RelA-dependent ppGpp synthesis
-
Bokinsky, G. et al. HipA-triggered growth arrest and beta-lactam tolerance in Escherichia coli is mediated by RelA-dependent ppGpp synthesis. J. Bacteriol. 195, 3173-3182 (2013).
-
(2013)
J. Bacteriol.
, vol.195
, pp. 3173-3182
-
-
Bokinsky, G.1
-
19
-
-
0018173271
-
Effect of inhibitors of elongation factor Tu on the metabolic regulation of protein synthesis in Escherichia coli
-
Young, F. S. & Neidhardt, F. C. Effect of inhibitors of elongation factor Tu on the metabolic regulation of protein synthesis in Escherichia coli. J. Bacteriol. 135, 675-686 (1978). (Pubitemid 9000289)
-
(1978)
Journal of Bacteriology
, vol.135
, Issue.2
, pp. 675-686
-
-
Young, F.S.1
Neidhardt, F.C.2
-
20
-
-
0031472242
-
The E coli signal recognition particle is required for the insertion of a subset of inner membrane proteins
-
DOI 10.1016/S0092-8674(00)81839-5
-
Ulbrandt, N. D., Newitt, J. A. & Bernstein, H. D. The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. Cell 88, 187-196 (1997). (Pubitemid 28015867)
-
(1997)
Cell
, vol.88
, Issue.2
, pp. 187-196
-
-
Ulbrandt, N.D.1
Newitt, J.A.2
Bernstein, H.D.3
-
21
-
-
0014478832
-
Two compounds implicated in the function of the RC gene of Escherichia coli
-
Cashel, M. & Gallant, J. Two compounds implicated in the function of the RC gene of Escherichia coli. Nature 221, 838-841 (1969).
-
(1969)
Nature
, vol.221
, pp. 838-841
-
-
Cashel, M.1
Gallant, J.2
-
22
-
-
77956342535
-
Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes
-
Levin-Reisman, I. et al. Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes. Nat. Methods 7, 737-739 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 737-739
-
-
Levin-Reisman, I.1
-
23
-
-
0015079354
-
Biochemical bases for the antimetabolite action of L-serine hydroxamate
-
Tosa, T. & Pizer, L. I. Biochemical bases for the antimetabolite action of L-serine hydroxamate. J. Bacteriol. 106, 972-982 (1971).
-
(1971)
J. Bacteriol.
, vol.106
, pp. 972-982
-
-
Tosa, T.1
Pizer, L.I.2
-
24
-
-
0037415750
-
ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
-
DOI 10.1093/emboj/cdg053
-
Sekine, S. et al. ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding. EMBO J. 22, 676-688 (2003). (Pubitemid 36193612)
-
(2003)
EMBO Journal
, vol.22
, Issue.3
, pp. 676-688
-
-
Sekine, S.-I.1
Nureki, O.2
Dubois, D.Y.3
Bernier, S.4
Chenevert, R.G.5
Lapointe, J.6
Vassylyev, D.G.7
Yokoyama, S.8
-
25
-
-
84886290812
-
Molecular mechanism of bacterial persistence by HipA
-
Germain, E., Castro-Roa, D., Zenkin, N. & Gerdes, K. Molecular mechanism of bacterial persistence by HipA. Mol. Cell 52, 248-254 (2013).
-
(2013)
Mol. Cell
, vol.52
, pp. 248-254
-
-
Germain, E.1
Castro-Roa, D.2
Zenkin, N.3
Gerdes, K.4
-
27
-
-
84872241785
-
Bacterial persistence and toxin-antitoxin loci
-
Gerdes, K. & Maisonneuve, E. Bacterial persistence and toxin-antitoxin loci. Annu. Rev. Microbiol. 66, 103-123 (2012).
-
(2012)
Annu. Rev. Microbiol.
, vol.66
, pp. 103-123
-
-
Gerdes, K.1
Maisonneuve, E.2
-
28
-
-
0030008368
-
An Escherichia coli chromosomal 'addiction module' regulated by guanosine [corrected] 30 , 50-bispyrophosphate: A model for programmed bacterial cell death
-
Aizenman, E., Engelberg-Kulka, H. & Glaser, G. An Escherichia coli chromosomal 'addiction module' regulated by guanosine [corrected] 30 , 50-bispyrophosphate: a model for programmed bacterial cell death. Proc. Natl Acad. Sci. USA 93, 6059-6063 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 6059-6063
-
-
Aizenman, E.1
Engelberg-Kulka, H.2
Glaser, G.3
-
29
-
-
0030771435
-
Guanosine tetra- and pentaphosphate promote accumulation of inorganic polyphosphate in Escherichia coli
-
DOI 10.1074/jbc.272.34.21240
-
Kuroda, A., Murphy, H., Cashel, M. & Kornberg, A. Guanosine tetra-and pentaphosphate promote accumulation of inorganic polyphosphate in Escherichia coli. J. Biol. Chem. 272, 21240-21243 (1997). (Pubitemid 27373988)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.34
, pp. 21240-21243
-
-
Kuroda, A.1
Murphy, H.2
Cashel, M.3
Kornberg, A.4
-
30
-
-
0035958678
-
Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E coli
-
Kuroda, A. et al. Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli. Science 293, 705-708 (2001). (Pubitemid 32728674)
-
(2001)
Science
, vol.293
, Issue.5530
, pp. 705-708
-
-
Kuroda, A.1
Nomura, K.2
Ohtomo, R.3
Kato, J.4
Ikeda, T.5
Takiguchi, N.6
Ohtake, H.7
Kornberg, A.8
-
31
-
-
84862505694
-
Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis
-
Hansen, S. et al. Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis. PLoS One 7, e39185 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Hansen, S.1
-
32
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
DOI 10.1126/science.1099390
-
Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L. & Leibler, S. Bacterial persistence as a phenotypic switch. Science 305, 1622-1625 (2004). (Pubitemid 39296357)
-
(2004)
Science
, vol.305
, Issue.5690
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
33
-
-
84866903496
-
Relacin, a novel antibacterial agent targeting the stringent response
-
Wexselblatt, E. et al. Relacin, a novel antibacterial agent targeting the stringent response. PLoS Pathog. 8, e1002925 (2012).
-
(2012)
PLoS Pathog.
, vol.8
-
-
Wexselblatt, E.1
-
34
-
-
79955886933
-
Metabolite-enabled eradication of bacterial persisters by aminoglycosides
-
Allison, K. R., Brynildsen, M. P. & Collins, J. J. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 473, 216-220 (2011).
-
(2011)
Nature
, vol.473
, pp. 216-220
-
-
Allison, K.R.1
Brynildsen, M.P.2
Collins, J.J.3
-
35
-
-
79960436674
-
Age of inoculum strongly influences persister frequency and can mask effects of mutations implicated in altered persistence
-
Luidalepp, H., Joers, A., Kaldalu, N. & Tenson, T. Age of inoculum strongly influences persister frequency and can mask effects of mutations implicated in altered persistence. J. Bacteriol. 193, 3598-3605 (2011).
-
(2011)
J. Bacteriol.
, vol.193
, pp. 3598-3605
-
-
Luidalepp, H.1
Joers, A.2
Kaldalu, N.3
Tenson, T.4
-
36
-
-
48749089081
-
Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli
-
Hansen, S., Lewis, K. & Vulic, M. Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrob. Agents Chemother 52, 2718-2726 (2008).
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, pp. 2718-2726
-
-
Hansen, S.1
Lewis, K.2
Vulic, M.3
-
37
-
-
84879728880
-
Molecular mechanisms of multiple toxinantitoxin systems are coordinated to govern the persister phenotype
-
Fasani, R. A. & Savageau, M. A. Molecular mechanisms of multiple toxinantitoxin systems are coordinated to govern the persister phenotype. Proc. Natl Acad. Sci. USA 110, E2528-E2537 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
-
-
Fasani, R.A.1
Savageau, M.A.2
-
38
-
-
66749179869
-
The importance of being persistent: Heterogeneity of bacterial populations under antibiotic stress
-
Gefen, O. & Balaban, N. Q. The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress. FEMS. Microbiol. Rev. 33, 704-717 (2009).
-
(2009)
FEMS. Microbiol. Rev.
, vol.33
, pp. 704-717
-
-
Gefen, O.1
Balaban, N.Q.2
-
39
-
-
0043192889
-
Mtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice
-
DOI 10.1073/pnas.1631248100
-
Dahl, J. L. et al. The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice. Proc. Natl Acad. Sci. USA 100, 10026-10031 (2003). (Pubitemid 37087062)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10026-10031
-
-
Dahl, J.L.1
Kraus, C.N.2
Boshoff, H.I.M.3
Doan, B.4
Foley, K.5
Avarbock, D.6
Kaplan, G.7
Mizrahi, V.8
Rubin, H.9
Barry III, C.E.10
-
40
-
-
0016283409
-
Culture medium for enterobacteria
-
Neidhardt, F. C., Bloch, P. L. & Smith, D. F. Culture medium for enterobacteria. J. Bacteriol. 119, 736-747 (1974).
-
(1974)
J. Bacteriol.
, vol.119
, pp. 736-747
-
-
Neidhardt, F.C.1
Bloch, P.L.2
Smith, D.F.3
|