-
2
-
-
77957947243
-
Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis
-
Mulcahy LR, Burns JL, Lory S, Lewis K. 2010. Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. J Bacteriol 192:6191–6199. http://dx.doi.org/10.1128/JB.01651-09.
-
(2010)
J Bacteriol
, vol.192
, pp. 6191-6199
-
-
Mulcahy, L.R.1
Burns, J.L.2
Lory, S.3
Lewis, K.4
-
3
-
-
84888019629
-
Activated ClpP kills persisters and eradicates a chronic biofilm infection
-
Conlon BP, Nakayasu ES, Fleck LE, LaFleur MD, Isabella VM, Coleman K, Leonard SN, Smith RD, Adkins JN, Lewis K. 2013. Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature 503: 365–370. http://dx.doi.org/10.1038/nature12790.
-
(2013)
Nature
, vol.503
, pp. 365-370
-
-
Conlon, B.P.1
Nakayasu, E.S.2
Fleck, L.E.3
Lafleur, M.D.4
Isabella, V.M.5
Coleman, K.6
Leonard, S.N.7
Smith, R.D.8
Adkins, J.N.9
Lewis, K.10
-
4
-
-
84892181925
-
Internalization of salmonella by macrophages induces formation of nonreplicating persisters
-
Helaine S, Cheverton AM, Watson KG, Faure LM, Matthews SA, Holden DW. 2014. Internalization of salmonella by macrophages induces formation of nonreplicating persisters. Science 343:204-208. http://dx.doi.org/10.1126/science.1244705.
-
(2014)
Science
, vol.343
, pp. 204-208
-
-
Helaine, S.1
Cheverton, A.M.2
Watson, K.G.3
Faure, L.M.4
Matthews, S.A.5
Holden, D.W.6
-
5
-
-
0038048322
-
Intracellular bacterial biofilm-like pods in urinary tract infections
-
Anderson GG, Palermo JJ, Schilling JD, Roth R, Heuser J, Hultgren SJ. 2003. Intracellular bacterial biofilm-like pods in urinary tract infections. Science 301:105–107. http://dx.doi.org/10.1126/science.1084550.
-
(2003)
Science
, vol.301
, pp. 105-107
-
-
Anderson, G.G.1
Palermo, J.J.2
Schilling, J.D.3
Roth, R.4
Heuser, J.5
Hultgren, S.J.6
-
6
-
-
10044266575
-
Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
-
Keren I, Shah D, Spoering A, Kaldalu N, Lewis K. 2004. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186:8172–8180. http://dx.doi.org/10.1128/JB.186.24.8172-8180.2004.
-
(2004)
J Bacteriol
, vol.186
, pp. 8172-8180
-
-
Keren, I.1
Shah, D.2
Spoering, A.3
Kaldalu, N.4
Lewis, K.5
-
7
-
-
33747436591
-
Persisters: A distinct physiological state of E. coli
-
Shah D, Zhang Z, Khodursky A, Kaldalu N, Kurg K, Lewis K. 2006. Persisters: a distinct physiological state of E. coli. BMC Microbiol 6:53.
-
(2006)
BMC Microbiol
, vol.6
, pp. 53
-
-
Shah, D.1
Zhang, Z.2
Khodursky, A.3
Kaldalu, N.4
Kurg, K.5
Lewis, K.6
-
8
-
-
84886290812
-
Molecular mechanism of bacterial persistence by HipA
-
Germain E, Castro-Roa D, Zenkin N, Gerdes K. 2013. Molecular mechanism of bacterial persistence by HipA. Mol Cell 52:248-254. http://dx.doi.org/10.1016/j.molcel.2013.08.045.
-
(2013)
Mol Cell
, vol.52
, pp. 248-254
-
-
Germain, E.1
Castro-Roa, D.2
Zenkin, N.3
Gerdes, K.4
-
9
-
-
84890639139
-
HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase
-
Kaspy I, Rotem E, Weiss N, Ronin I, Balaban NQ, Glaser G. 2013. HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase. Nat Commun 4:3001. http://dx.doi.org/10.1038/ncomms4001.
-
(2013)
Nat Commun
, vol.4
, pp. 3001
-
-
Kaspy, I.1
Rotem, E.2
Weiss, N.3
Ronin, I.4
Balaban, N.Q.5
Glaser, G.6
-
10
-
-
58449087611
-
Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB
-
Schumacher MA, Piro KM, Xu W, Hansen S, Lewis K, Brennan RG. 2009. Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science 323:396-401. http://dx.doi.org/10.1126/science.1163806.
-
(2009)
Science
, vol.323
, pp. 396-401
-
-
Schumacher, M.A.1
Piro, K.M.2
Xu, W.3
Hansen, S.4
Lewis, K.5
Brennan, R.G.6
-
12
-
-
84864281978
-
Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers
-
Gurnev PA, Ortenberg R, Dörr T, Lewis K, Bezrukov SM. 2012. Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers. FEBS Lett 586:2529-2534. http://dx.doi.org/10.1016/j.febslet.2012.06.021.
-
(2012)
FEBS Lett
, vol.586
, pp. 2529-2534
-
-
Gurnev, P.A.1
Ortenberg, R.2
Dörr, T.3
Lewis, K.4
Bezrukov, S.M.5
-
13
-
-
77649174212
-
Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli
-
Dörr T, Vulic´ M, Lewis K. 2010. Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. PLoS Biol 8:e1000317. http://dx.doi.org/10.1371/journal.pbio.1000317.
-
(2010)
Plos Biol
, vol.8
-
-
Dörr, T.1
Vulic´, M.2
Lewis, K.3
-
14
-
-
12844259655
-
Transposon mutagenesis identifies genes which control antimicrobial drug tolerance in stationary-phase Escherichia coli
-
Hu Y, Coates AR. 2005. Transposon mutagenesis identifies genes which control antimicrobial drug tolerance in stationary-phase Escherichia coli. FEMS Microbiol Lett 243:117–124. http://dx.doi.org/10.1016/j.femsle.2004.11.049.
-
(2005)
FEMS Microbiol Lett
, vol.243
, pp. 117-124
-
-
Hu, Y.1
Coates, A.R.2
-
15
-
-
48749089081
-
Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli
-
Hansen S, Lewis K, Vulic´ M. 2008. Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrob Agents Chemother 52:2718–2726. http://dx.doi.org/10.1128/AAC.00144-08.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2718-2726
-
-
Hansen, S.1
Lewis, K.2
Vulic´, M.3
-
16
-
-
33745904995
-
GlpD and PlsB participate in persister cell formation in Escherichia coli
-
Spoering AL, Vulic M, Lewis K. 2006. GlpD and PlsB participate in persister cell formation in Escherichia coli. J Bacteriol 188:5136-5144. http://dx.doi.org/10.1128/JB.00369-06.
-
(2006)
J Bacteriol
, vol.188
, pp. 5136-5144
-
-
Spoering, A.L.1
Vulic, M.2
Lewis, K.3
-
17
-
-
84873500633
-
Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin
-
Bernier SP, Lebeaux D, DeFrancesco AS, Valomon A, Soubigou G, Coppée JY, Ghigo JM, Beloin C. 2013. Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin. PLoS Genet 9:e1003144. http://dx.doi.org/10.1371/journal.pgen.1003144.
-
(2013)
Plos Genet
, vol.9
-
-
Bernier, S.P.1
Lebeaux, D.2
Defrancesco, A.S.3
Valomon, A.4
Soubigou, G.5
Coppée, J.Y.6
Ghigo, J.M.7
Beloin, C.8
-
18
-
-
70349611730
-
Tn-seq: High-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
-
Van Opijnen T, Bodi KL, Camilli A. 2009. Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms. Nat Methods 6:767–772. http://dx.doi.org/10.1038/nmeth.1377.
-
(2009)
Nat Methods
, vol.6
, pp. 767-772
-
-
Van Opijnen, T.1
Bodi, K.L.2
Camilli, A.3
-
20
-
-
84887321144
-
Aminoglycosides: How should we use them in the 21st century?
-
Jackson J, Chen C, Buising K. 2013. Aminoglycosides: how should we use them in the 21st century? Curr Opin Infect Dis 26:516-525. http://dx.doi.org/10.1097/QCO.0000000000000012.
-
(2013)
Curr Opin Infect Dis
, vol.26
, pp. 516-525
-
-
Jackson, J.1
Chen, C.2
Buising, K.3
-
21
-
-
0023615466
-
Mechanism of bactericidal action of aminoglycosides
-
Davis BD. 1987. Mechanism of bactericidal action of aminoglycosides. Microbiol Rev 51:341–350.
-
(1987)
Microbiol Rev
, vol.51
, pp. 341-350
-
-
Davis, B.D.1
-
23
-
-
84876556918
-
EcoCyc: Fusing model organism databases with systems biology
-
Keseler IM, Mackie A, Peralta-Gil M, Santos-Zavaleta A, Gama-Castro S, Bonavides-Martínez C, Fulcher C, Huerta AM, Kothari A, Krummenacker M, Latendresse M, Muñiz-Rascado L, Ong Q, Paley S, Schröder I, Shearer AG, Subhraveti P, Travers M, Weerasinghe D, Weiss V, Collado-Vides J, Gunsalus RP, Paulsen I, Karp PD. 2013. EcoCyc: fusing model organism databases with systems biology. Nucleic Acids Res 41:D605–D612. http://dx.doi.org/10.1093/nar/gks1027.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D605-D612
-
-
Keseler, I.M.1
Mackie, A.2
Peralta-Gil, M.3
Santos-Zavaleta, A.4
Gama-Castro, S.5
Bonavides-Martínez, C.6
Fulcher, C.7
Huerta, A.M.8
Kothari, A.9
Krummenacker, M.10
Latendresse, M.11
Muñiz-Rascado, L.12
Ong, Q.13
Paley, S.14
Schröder, I.15
Shearer, A.G.16
Subhraveti, P.17
Travers, M.18
Weerasinghe, D.19
Weiss, V.20
Collado-Vides, J.21
Gunsalus, R.P.22
Paulsen, I.23
Karp, P.D.24
more..
-
24
-
-
0017644533
-
Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: A model for entry of streptomycin and gentamicin in susceptible and resistant bacteria
-
Bryan LE, Van Den Elzen HM. 1977. Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: a model for entry of streptomycin and gentamicin in susceptible and resistant bacteria. Antimicrob Agents Chemother 12:163–177. http://dx.doi.org/10.1128/AAC.12.2.163.
-
(1977)
Antimicrob Agents Chemother
, vol.12
, pp. 163-177
-
-
Bryan, L.E.1
Van Den Elzen, H.M.2
-
25
-
-
33745881353
-
The QseC sensor kinase: A bacterial adrenergic receptor
-
Clarke MB, Hughes DT, Zhu C, Boedeker EC, Sperandio V. 2006. The QseC sensor kinase: a bacterial adrenergic receptor. Proc Natl Acad Sci U S A 103:10420–10425. http://dx.doi.org/10.1073/pnas.0604343103.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10420-10425
-
-
Clarke, M.B.1
Hughes, D.T.2
Zhu, C.3
Boedeker, E.C.4
Sperandio, V.5
-
26
-
-
84906935104
-
Biofilms, flagella, and mechanosensing of surfaces by bacteria
-
Belas R. 2014. Biofilms, flagella, and mechanosensing of surfaces by bacteria. Trends Microbiol 22:517–527. http://dx.doi.org/10.1016/j.tim.2014.05.002.
-
(2014)
Trends Microbiol
, vol.22
, pp. 517-527
-
-
Belas, R.1
-
27
-
-
57149114304
-
Flagellar motility in bacteria structure and function of flagellar motor
-
Terashima H, Kojima S, Homma M. 2008. Flagellar motility in bacteria structure and function of flagellar motor. Int Rev Cell Mol Biol 270: 39–85. http://dx.doi.org/10.1016/S1937-6448(08)01402-0.
-
(2008)
Int Rev Cell Mol Biol
, vol.270
, pp. 39-85
-
-
Terashima, H.1
Kojima, S.2
Homma, M.3
-
28
-
-
0027048626
-
Genetics and biogenesis of bacterial flagella
-
Macnab RM. 1992. Genetics and biogenesis of bacterial flagella. Annu Rev Genet 26:131–158. http://dx.doi.org/10.1146/annurev.ge.26.120192.001023.
-
(1992)
Annu Rev Genet
, vol.26
, pp. 131-158
-
-
Macnab, R.M.1
-
29
-
-
84883342218
-
(P)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity
-
Maisonneuve E, Castro-Camargo M, Gerdes K. 2013. (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 154:1140–1150. http://dx.doi.org/10.1016/j.cell.2013.07.048.
-
(2013)
Cell
, vol.154
, pp. 1140-1150
-
-
Maisonneuve, E.1
Castro-Camargo, M.2
Gerdes, K.3
-
30
-
-
84888991522
-
Tolerance of Escherichia coli to fluoroquinolone antibiotics depends on specific components of the SOS response pathway
-
Theodore A, Lewis K, Vulic M. 2013. Tolerance of Escherichia coli to fluoroquinolone antibiotics depends on specific components of the SOS response pathway. Genetics 195:1265–1276. http://dx.doi.org/10.1534/genetics.113.152306.
-
(2013)
Genetics
, vol.195
, pp. 1265-1276
-
-
Theodore, A.1
Lewis, K.2
Vulic, M.3
-
31
-
-
27744557363
-
Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization
-
Wright KJ, Seed PC, Hultgren SJ. 2005. Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. Infect Immun 73: 7657–7668. http://dx.doi.org/10.1128/IAI.73.11.7657-7668.2005.
-
(2005)
Infect Immun
, vol.73
, pp. 7657-7668
-
-
Wright, K.J.1
Seed, P.C.2
Hultgren, S.J.3
-
32
-
-
40449091818
-
The Rcs phosphorelay is a cell envelope stress response activated by peptidoglycan stress and contributes to intrinsic antibiotic resistance
-
Laubacher ME, Ades SE. 2008. The Rcs phosphorelay is a cell envelope stress response activated by peptidoglycan stress and contributes to intrinsic antibiotic resistance. J Bacteriol 190:2065–2074. http://dx.doi.org/10.1128/JB.01740-07.
-
(2008)
J Bacteriol
, vol.190
, pp. 2065-2074
-
-
Laubacher, M.E.1
Ades, S.E.2
-
34
-
-
84879615674
-
Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway
-
Ezraty B, Vergnes A, Banzhaf M, Duverger Y, Huguenot A, Brochado AR, Su SY, Espinosa L, Loiseau L, Py B, Typas A, Barras F. 2013. Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway. Science 340:1583–1587. http://dx.doi.org/10.1126/science.1238328.
-
(2013)
Science
, vol.340
, pp. 1583-1587
-
-
Ezraty, B.1
Vergnes, A.2
Banzhaf, M.3
Duverger, Y.4
Huguenot, A.5
Brochado, A.R.6
Su, S.Y.7
Espinosa, L.8
Loiseau, L.9
Py, B.10
Typas, A.11
Barras, F.12
-
35
-
-
84876226087
-
Chaperonins fight aminoglycoside-induced protein misfolding and promote short-term tolerance in Escherichia coli
-
Goltermann L, Good L, Bentin T. 2013. Chaperonins fight aminoglycoside-induced protein misfolding and promote short-term tolerance in Escherichia coli. J Biol Chem 288:10483–10489. http://dx.doi.org/10.1074/jbc.M112.420380.
-
(2013)
J Biol Chem
, vol.288
, pp. 10483-10489
-
-
Goltermann, L.1
Good, L.2
Bentin, T.3
-
36
-
-
0020590028
-
Hipa, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
-
Moyed HS, Bertrand KP. 1983. Hipa, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J Bacteriol 155:768–775.
-
(1983)
J Bacteriol
, vol.155
, pp. 768-775
-
-
Moyed, H.S.1
Bertrand, K.P.2
-
37
-
-
31544450286
-
2006. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H. 2006. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2:2006.0008. http://dx.doi.org/10.1038/msb4100050.
-
(2006)
Mol Syst Biol
, vol.2
, pp. 0008
-
-
Baba, T.1
Ara, T.2
Hasegawa, M.3
Takai, Y.4
Okumura, Y.5
Baba, M.6
Datsenko, K.A.7
Tomita, M.8
Wanner, B.L.9
Mori, H.10
-
39
-
-
84868260243
-
Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis
-
Klein BA, Tenorio EL, Lazinski DW, Camilli A, Duncan MJ, Hu LT. 2012. Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis. BMC Genomics 13:578. http://dx.doi.org/10.1186/1471-2164-13-578.
-
(2012)
BMC Genomics
, vol.13
, pp. 578
-
-
Klein, B.A.1
Tenorio, E.L.2
Lazinski, D.W.3
Camilli, A.4
Duncan, M.J.5
Hu, L.T.6
-
40
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10:R25. http://dx.doi.org/10.1186/gb-2009-10-3-r25.
-
(2009)
Genome Biol
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
41
-
-
0034924241
-
Determination of minimum inhibitory concentrations
-
Andrews JM. 2001. Determination of minimum inhibitory concentrations. J Antimicrob Chemother 48(Suppl 1):5–16. http://dx.doi.org/10.1093/jac/48.suppl_1.5.
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 5-16
-
-
Andrews, J.M.1
-
42
-
-
0022477057
-
Mechanisms of gentamicin transport in kidney epithelial cell line (LLC-PK1)
-
Saito H, Inui K, Hori R. 1986. Mechanisms of gentamicin transport in kidney epithelial cell line (LLC-PK1). J Pharmacol Exp Ther 238:1071–1076.
-
(1986)
J Pharmacol Exp Ther
, vol.238
, pp. 1071-1076
-
-
Saito, H.1
Inui, K.2
Hori, R.3
|