Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

Nature Microbiology

Volumn 1, Issue 5, 2016, Pages

  Van Den Bergh, Bram ^a   Michiels, Joran E ^a   Wenseleers, Tom ^a   Windels, Etthel M ^a   Boer, Pieterjan Vanden ^a   Kestemont, Donaat ^a   De Meester, Luc ^a   Verstrepen, Kevin J ^a,b   Verstraeten, Natalie ^a   Fauvart, Maarten ^a,c   Michiels, Jan ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c IMEC   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; GENTAMICIN; KANAMYCIN; OFLOXACIN; TOBRAMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DIAGNOSTIC TEST; DRUG DOSE REGIMEN; DRUG TOLERANCE; ESCHERICHIA COLI; EVOLUTIONARY ADAPTATION; MATHEMATICAL MODEL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; DRUG UTILIZATION; PHYSIOLOGY;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; DRUG TOLERANCE; DRUG UTILIZATION; ESCHERICHIA COLI;

EID: 84975170433     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/nmicrobiol.2016.20     Document Type: Article

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