Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

Cell Reports

Volumn 12, Issue 9, 2015, Pages 1497-1507

  Harms, Alexander ^a   Stanger, Frédéric Valentin ^a   Scheu, Patrick Daniel ^b   de Jong, Imke Greet ^a   Goepfert, Arnaud ^a,d   Glatter, Timo ^a   Gerdes, Kenn ^b,c   Schirmer, Tilman ^a   Dehio, Christoph ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL TOXIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; FICT TOXIN; PROTEIN PARE; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN;

ADENYLATION; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA STRUCTURE; ENZYME INHIBITION; ESCHERICHIA COLI; GROWTH INHIBITION; HYDROLYSIS; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; CHEMISTRY; CONFORMATION; METABOLISM; PSEUDOMONAS AERUGINOSA;

BACTERIAL TOXINS; DNA GYRASE; DNA TOPOISOMERASE IV; DNA, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; NUCLEIC ACID CONFORMATION; PSEUDOMONAS AERUGINOSA;

EID: 84940787947     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.07.056     Document Type: Article

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