메뉴 건너뛰기




Volumn 15, Issue 24, 2016, Pages 3442-3453

Persistence to anti-cancer treatments in the stationary to proliferating transition

Author keywords

cell cycle; chemotherapy; microfluidics; persistence; proliferating; quiescence; stationary

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; CYTARABINE; VINCRISTINE; UBIQUITIN;

EID: 84995390385     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2016.1248006     Document Type: Article
Times cited : (31)

References (68)
  • 1
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • 17957189
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007; 7:834-46; PMID:17957189
    • (2007) Nat Rev Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 2
    • 79955886933 scopus 로고    scopus 로고
    • Metabolite-enabled eradication of bacterial persisters by aminoglycosides
    • 21562562
    • Allison KR, Brynildsen MP, Collins JJ. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 2011; 473:216-20; PMID:21562562; http://dx.doi.org/10.1038/nature10069
    • (2011) Nature , vol.473 , pp. 216-220
    • Allison, K.R.1    Brynildsen, M.P.2    Collins, J.J.3
  • 3
    • 74049121331 scopus 로고    scopus 로고
    • Contribution of bone microenvironment to leukemogenesis and leukemia progression
    • 19727127
    • Ayala F, Dewar R, Kieran M, Kalluri R. Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia 2009; 23:2233-41; PMID:19727127; http://dx.doi.org/10.1038/leu.2009.175
    • (2009) Leukemia , vol.23 , pp. 2233-2241
    • Ayala, F.1    Dewar, R.2    Kieran, M.3    Kalluri, R.4
  • 4
    • 81955167411 scopus 로고    scopus 로고
    • Persistence: mechanisms for triggering and enhancing phenotypic variability
    • 22051606
    • Balaban N. Persistence:mechanisms for triggering and enhancing phenotypic variability. Curr Opin Genet Dev 2011; 21:768-75; PMID:22051606; http://dx.doi.org/10.1016/j.gde.2011.10.001
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 768-775
    • Balaban, N.1
  • 5
    • 4644343922 scopus 로고    scopus 로고
    • Bacterial Persistence as a Phenotypic Switch
    • 15308767
    • Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S. Bacterial Persistence as a Phenotypic Switch. Science 2004; 305:1622-5; PMID:15308767; http://dx.doi.org/10.1126/science.1099390
    • (2004) Science , vol.305 , pp. 1622-1625
    • Balaban, N.Q.1    Merrin, J.2    Chait, R.3    Kowalik, L.4    Leibler, S.5
  • 6
    • 0015296596 scopus 로고
    • Cell cycle phase specificity of antitumor agents
    • 4258018
    • Bhuyan BK, Scheidt LG, Fraser TJ. Cell cycle phase specificity of antitumor agents. Cancer Res 1972; 32:398-407; PMID:4258018
    • (1972) Cancer Res , vol.32 , pp. 398-407
    • Bhuyan, B.K.1    Scheidt, L.G.2    Fraser, T.J.3
  • 7
    • 0017597307 scopus 로고
    • Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells
    • 139202
    • Bhuyan BK, Fraser TJ, Day KJ. Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells. Cancer Res 1977; 37:1057-63; PMID:139202
    • (1977) Cancer Res , vol.37 , pp. 1057-1063
    • Bhuyan, B.K.1    Fraser, T.J.2    Day, K.J.3
  • 8
    • 50349141358 scopus 로고
    • Treatment of staphylococcal infections with penicillin by intermittent sterilisation
    • Bigger J. Treatment of staphylococcal infections with penicillin by intermittent sterilisation. The Lancet 1944; 244:497-500; http://dx.doi.org/10.1016/S0140-6736(00)74210-3
    • (1944) The Lancet , vol.244 , pp. 497-500
    • Bigger, J.1
  • 9
    • 0037068773 scopus 로고    scopus 로고
    • Sequential activation and inactivation of G2 checkpoints for selective killing of p53-deficient cells by microtubule-active drugs
    • 12214265
    • Blagosklonny MV. Sequential activation and inactivation of G2 checkpoints for selective killing of p53-deficient cells by microtubule-active drugs. Oncogene 2002; 21:6249-54; PMID:12214265; http://dx.doi.org/10.1038/sj.onc.1205793
    • (2002) Oncogene , vol.21 , pp. 6249-6254
    • Blagosklonny, M.V.1
  • 10
    • 33644520922 scopus 로고    scopus 로고
    • Target for cancer therapy: proliferating cells or stem cells
    • 16357832
    • Blagosklonny MV. Target for cancer therapy:proliferating cells or stem cells. Leukemia 2006; 20:385-91; PMID:16357832; http://dx.doi.org/10.1038/sj.leu.2404075
    • (2006) Leukemia , vol.20 , pp. 385-391
    • Blagosklonny, M.V.1
  • 11
    • 0035359505 scopus 로고    scopus 로고
    • Exploiting cancer cell cycling for selective protection of normal cells
    • 11389048
    • Blagosklonny MV, Pardee AB. Exploiting cancer cell cycling for selective protection of normal cells. Cancer Res 2001; 61:4301-5; PMID:11389048
    • (2001) Cancer Res , vol.61 , pp. 4301-4305
    • Blagosklonny, M.V.1    Pardee, A.B.2
  • 12
    • 24944508703 scopus 로고    scopus 로고
    • Normal and leukaemic stem cells
    • 16098060
    • Bonnet D. Normal and leukaemic stem cells. Br J Haematol 2005; 130:469-79; PMID:16098060; http://dx.doi.org/10.1111/j.1365-2141.2005.05596.x
    • (2005) Br J Haematol , vol.130 , pp. 469-479
    • Bonnet, D.1
  • 13
    • 84964318468 scopus 로고    scopus 로고
    • Distinguishing between resistance, tolerance and persistence to antibiotic treatment
    • 27080241
    • Brauner A, Fridman O, Gefen O, Balaban NQ. Distinguishing between resistance, tolerance and persistence to antibiotic treatment. Nat Rev Microbiol 2016; 14:320-30; PMID:27080241; http://dx.doi.org/10.1038/nrmicro.2016.34
    • (2016) Nat Rev Microbiol , vol.14 , pp. 320-330
    • Brauner, A.1    Fridman, O.2    Gefen, O.3    Balaban, N.Q.4
  • 14
    • 67349284051 scopus 로고    scopus 로고
    • Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours
    • 19337290
    • Brock A, Chang H, Huang S. Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours. Nat Rev Genet 2009; 10:336-42; PMID:19337290; http://dx.doi.org/10.1038/nrg2556
    • (2009) Nat Rev Genet , vol.10 , pp. 336-342
    • Brock, A.1    Chang, H.2    Huang, S.3
  • 15
    • 0035138459 scopus 로고    scopus 로고
    • Retreatment of patients with the same chemotherapy: implications for clinical mechanisms of drug resistance
    • 11249045
    • Cara S, Tannock IF. Retreatment of patients with the same chemotherapy:implications for clinical mechanisms of drug resistance. Ann Oncol 2001; 12:23-7; PMID:11249045; http://dx.doi.org/10.1023/A:1008389706725
    • (2001) Ann Oncol , vol.12 , pp. 23-27
    • Cara, S.1    Tannock, I.F.2
  • 16
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • 22854781
    • Chen J, Li Y, Yu T-S, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012; 488:522-6; PMID:22854781; http://dx.doi.org/10.1038/nature11287
    • (2012) Nature , vol.488 , pp. 522-526
    • Chen, J.1    Li, Y.2    Yu, T.-S.3    McKay, R.M.4    Burns, D.K.5    Kernie, S.G.6    Parada, L.F.7
  • 17
    • 0027443181 scopus 로고
    • The role of hypoxia in the maintenance of hematopoietic stem cells
    • 8104535
    • Cipolleschi MG, Sbarba PD, Olivotto M. The role of hypoxia in the maintenance of hematopoietic stem cells. Blood 1993; 82:2031-7; PMID:8104535
    • (1993) Blood , vol.82 , pp. 2031-2037
    • Cipolleschi, M.G.1    Sbarba, P.D.2    Olivotto, M.3
  • 19
    • 0038386385 scopus 로고    scopus 로고
    • Rethinking synchronization of mammalian cells for cell cycle analysis
    • Cooper S. Rethinking synchronization of mammalian cells for cell cycle analysis. Cell Mol Life Sci CMLS 2003; 60:1099-106.
    • (2003) Cell Mol Life Sci CMLS , vol.60 , pp. 1099-1106
    • Cooper, S.1
  • 20
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: models and concepts
    • 17002552
    • Dalerba P, Cho RW, Clarke MF. Cancer stem cells:models and concepts. Annu Rev Med 2007; 58:267-84; PMID:17002552; http://dx.doi.org/10.1146/annurev.med.58.062105.204854
    • (2007) Annu Rev Med , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 21
    • 84856753762 scopus 로고    scopus 로고
    • The essence of yeast quiescence
    • 21658086
    • De Virgilio C. The essence of yeast quiescence. Fems Microbiol Rev 2012; 36:306-39; PMID:21658086; http://dx.doi.org/10.1111/j.1574-6976.2011.00287.x
    • (2012) Fems Microbiol Rev , vol.36 , pp. 306-339
    • De Virgilio, C.1
  • 22
    • 84990581159 scopus 로고
    • Cultured human tumour cells may be arrested in all stages of the cycle during stationary phase: demonstration of quiescent cells in G1, S and G2 phase
    • 6467330
    • Drewinko B, Yang LY, Barlogie B, Trujillo JM. Cultured human tumour cells may be arrested in all stages of the cycle during stationary phase:demonstration of quiescent cells in G1, S and G2 phase. Cell Prolif 1984; 17:453-63; PMID:6467330; http://dx.doi.org/10.1111/j.1365-2184.1984.tb00604.x
    • (1984) Cell Prolif , vol.17 , pp. 453-463
    • Drewinko, B.1    Yang, L.Y.2    Barlogie, B.3    Trujillo, J.M.4
  • 24
    • 77956611808 scopus 로고    scopus 로고
    • Targeting leukemic stem cells by breaking their dormancy
    • 20599449
    • Essers MAG, Trumpp A. Targeting leukemic stem cells by breaking their dormancy. Mol Oncol 2010; 4:443-50; PMID:20599449; http://dx.doi.org/10.1016/j.molonc.2010.06.001
    • (2010) Mol Oncol , vol.4 , pp. 443-450
    • Essers, M.A.G.1    Trumpp, A.2
  • 25
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
    • 18656424
    • Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008; 14:111-22; PMID:18656424; http://dx.doi.org/10.1016/j.ccr.2008.07.002
    • (2008) Cancer Cell , vol.14 , pp. 111-122
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 26
    • 43149116340 scopus 로고    scopus 로고
    • Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria
    • 18427112
    • Gefen O, Gabay C, Mumcuoglu M, Engel G, Balaban NQ. Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria. Proc Natl Acad Sci 2008; 105:6145-9; PMID:18427112; http://dx.doi.org/10.1073/pnas.0711712105
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 6145-6149
    • Gefen, O.1    Gabay, C.2    Mumcuoglu, M.3    Engel, G.4    Balaban, N.Q.5
  • 27
    • 77958014613 scopus 로고    scopus 로고
    • How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
    • 20877357
    • Gerlinger M, Swanton C. How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine. Br J Cancer 2010; 103:1139-43; PMID:20877357; http://dx.doi.org/10.1038/sj.bjc.6605912
    • (2010) Br J Cancer , vol.103 , pp. 1139-1143
    • Gerlinger, M.1    Swanton, C.2
  • 28
    • 33745198035 scopus 로고    scopus 로고
    • Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations
    • 16710305
    • Giuntoli S, Rovida E, Barbetti V, Cipolleschi MG, Olivotto M, Sbarba PD. Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations. Leukemia 2006; 20:1291-3; PMID:16710305; http://dx.doi.org/10.1038/sj.leu.2404224
    • (2006) Leukemia , vol.20 , pp. 1291-1293
    • Giuntoli, S.1    Rovida, E.2    Barbetti, V.3    Cipolleschi, M.G.4    Olivotto, M.5    Sbarba, P.D.6
  • 29
    • 0014871577 scopus 로고
    • The effect of 1-β-d-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells
    • 5530557
    • Graham FL, Whitmore GF. The effect of 1-β-d-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells. Cancer Res 1970; 30:2627-35; PMID:5530557
    • (1970) Cancer Res , vol.30 , pp. 2627-2635
    • Graham, F.L.1    Whitmore, G.F.2
  • 30
    • 0037606054 scopus 로고    scopus 로고
    • Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
    • 12468427
    • Guan Y, Gerhard B, Hogge DE. Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood 2003; 101:3142-9; PMID:12468427; http://dx.doi.org/10.1182/blood-2002-10-3062
    • (2003) Blood , vol.101 , pp. 3142-3149
    • Guan, Y.1    Gerhard, B.2    Hogge, D.E.3
  • 31
    • 79958718279 scopus 로고    scopus 로고
    • Cancer cells cyclically lose and regain drug-resistant highly tumorigenic features characteristic of a cancer stem-like phenotype
    • 21518726
    • He K, Xu T, Goldkorn A. Cancer cells cyclically lose and regain drug-resistant highly tumorigenic features characteristic of a cancer stem-like phenotype. Mol Cancer Ther 2011; 10:938-48; PMID:21518726; http://dx.doi.org/10.1158/1535-7163.MCT-10-1120
    • (2011) Mol Cancer Ther , vol.10 , pp. 938-948
    • He, K.1    Xu, T.2    Goldkorn, A.3
  • 32
    • 0021242388 scopus 로고
    • Tumor heterogeneity
    • 6372991
    • Heppner GH. Tumor heterogeneity. Cancer Res 1984; 44:2259-65; PMID:6372991
    • (1984) Cancer Res , vol.44 , pp. 2259-2265
    • Heppner, G.H.1
  • 33
    • 0016793538 scopus 로고
    • The cell cycle and its significance for cancer treatment
    • 1104161
    • Hill BT, Baserga R. The cell cycle and its significance for cancer treatment. Cancer Treat Rev 1975; 2:159-75; PMID:1104161; http://dx.doi.org/10.1016/S0305-7372(75)80001-6
    • (1975) Cancer Treat Rev , vol.2 , pp. 159-175
    • Hill, B.T.1    Baserga, R.2
  • 34
    • 0016847065 scopus 로고
    • Letter: kinetic classifications of antitumour drugs
    • 1156762
    • Hill BT, Price LA. Letter:kinetic classifications of antitumour drugs. Br Med J 1975; 3:367-7; PMID:1156762; http://dx.doi.org/10.1136/bmj.3.5979.367
    • (1975) Br Med J , vol.3 , pp. 367
    • Hill, B.T.1    Price, L.A.2
  • 35
    • 0025973329 scopus 로고
    • In vitro sensitivity assays in cancer: A review, analysis, and prognosis
    • 2023059
    • Hoffman RM. In vitro sensitivity assays in cancer:A review, analysis, and prognosis. J Clin Lab Anal 1991; 5:133-43; PMID:2023059; http://dx.doi.org/10.1002/jcla.1860050211
    • (1991) J Clin Lab Anal , vol.5 , pp. 133-143
    • Hoffman, R.M.1
  • 36
    • 0033568250 scopus 로고    scopus 로고
    • Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
    • 10477735
    • Holyoake T, Jiang X, Eaves C, Eaves A. Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood 1999; 94:2056-64; PMID:10477735
    • (1999) Blood , vol.94 , pp. 2056-2064
    • Holyoake, T.1    Jiang, X.2    Eaves, C.3    Eaves, A.4
  • 37
    • 33748891391 scopus 로고    scopus 로고
    • Cancer stem cells
    • 16990388
    • Jordan CT, Guzman ML, Noble M. Cancer stem cells. N Engl J Med 2006; 355:1253-61; PMID:16990388; http://dx.doi.org/10.1056/NEJMra061808
    • (2006) N Engl J Med , vol.355 , pp. 1253-1261
    • Jordan, C.T.1    Guzman, M.L.2    Noble, M.3
  • 38
    • 0033678457 scopus 로고    scopus 로고
    • Increased cellular hypoxia and reduced proliferation of both normal and leukaemic cells during progression of acute myeloid leukaemia in rats
    • Jensen P, Mortensen BT, Hodgkiss RJ, Iversen PO, Christensen IJ, Helledie N, and Larsen JK. Increased cellular hypoxia and reduced proliferation of both normal and leukaemic cells during progression of acute myeloid leukaemia in rats. Cell Prolif 2000; 33:381–395.
    • (2000) Cell Prolif , vol.33 , pp. 381-395
    • Jensen, P.1    Mortensen, B.T.2    Hodgkiss, R.J.3    Iversen, P.O.4    Christensen, I.J.5    Helledie, N.6    Larsen, J.K.7
  • 40
    • 21744437791 scopus 로고    scopus 로고
    • Repopulation of cancer cells during therapy: an important cause of treatment failure
    • 15965493
    • Kim JJ, Tannock IF. Repopulation of cancer cells during therapy:an important cause of treatment failure. Nat Rev Cancer 2005; 5:516-25; PMID:15965493; http://dx.doi.org/10.1038/nrc1650
    • (2005) Nat Rev Cancer , vol.5 , pp. 516-525
    • Kim, J.J.1    Tannock, I.F.2
  • 42
    • 34547640147 scopus 로고    scopus 로고
    • The evolving concept of tumor microenvironments
    • 17621638
    • Laconi E. The evolving concept of tumor microenvironments. BioEssays 2007; 29:738-44; PMID:17621638; http://dx.doi.org/10.1002/bies.20606
    • (2007) BioEssays , vol.29 , pp. 738-744
    • Laconi, E.1
  • 43
    • 79955518863 scopus 로고    scopus 로고
    • Metabolic status rather than cell cycle signals control quiescence entry and exit
    • 21402786
    • Laporte D, Lebaudy A, Sahin A, Pinson B, Ceschin J, Daignan-Fornier B, Sagot I. Metabolic status rather than cell cycle signals control quiescence entry and exit. J Cell Biol 2011; 192:949-57; PMID:21402786; http://dx.doi.org/10.1083/jcb.201009028
    • (2011) J Cell Biol , vol.192 , pp. 949-957
    • Laporte, D.1    Lebaudy, A.2    Sahin, A.3    Pinson, B.4    Ceschin, J.5    Daignan-Fornier, B.6    Sagot, I.7
  • 44
    • 84868615579 scopus 로고    scopus 로고
    • Cyclotherapy: opening a therapeutic window in cancer treatment
    • 22711025
    • van Leeuwen IMM. Cyclotherapy:opening a therapeutic window in cancer treatment. Oncotarget 2012; 3:596-600; PMID:22711025; http://dx.doi.org/10.18632/oncotarget.524
    • (2012) Oncotarget , vol.3 , pp. 596-600
    • van Leeuwen, I.M.M.1
  • 45
    • 84860780032 scopus 로고    scopus 로고
    • An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells
    • van Leeuwen IMM, Rao B, Sachweh MCC, Laín S. An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells. Cell Cycle Georget Tex 2012; 11:1851-61.
    • (2012) Cell Cycle Georget Tex , vol.11 , pp. 1851-1861
    • van Leeuwen, I.M.M.1    Rao, B.2    Sachweh, M.C.C.3    Laín, S.4
  • 46
    • 77955628762 scopus 로고    scopus 로고
    • Persister cells
    • 20528688
    • Lewis K. Persister cells. Annu Rev Microbiol 2010; 64:357-72; PMID:20528688; http://dx.doi.org/10.1146/annurev.micro.112408.134306
    • (2010) Annu Rev Microbiol , vol.64 , pp. 357-372
    • Lewis, K.1
  • 47
    • 0014384195 scopus 로고
    • Interphase action of vinblastine and vincristine: differences in their lethal action through the mitotic cycle of cultured mammalian cells
    • 5724569
    • Madoc-Jones H, Mauro F. Interphase action of vinblastine and vincristine:differences in their lethal action through the mitotic cycle of cultured mammalian cells. J Cell Physiol 1968; 72:185-95; PMID:5724569; http://dx.doi.org/10.1002/jcp.1040720306
    • (1968) J Cell Physiol , vol.72 , pp. 185-195
    • Madoc-Jones, H.1    Mauro, F.2
  • 48
    • 84923613955 scopus 로고    scopus 로고
    • Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging
    • Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Matsumoto Y, Uehara F, Hiroshima Y, Murakami T, Hayashi K, et al. Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging. Cell Cycle 2014; 14:621-9; http://dx.doi.org/10.4161/15384101.2014.991604
    • (2014) Cell Cycle , vol.14 , pp. 621-629
    • Miwa, S.1    Yano, S.2    Kimura, H.3    Yamamoto, M.4    Toneri, M.5    Matsumoto, Y.6    Uehara, F.7    Hiroshima, Y.8    Murakami, T.9    Hayashi, K.10
  • 49
    • 84943745164 scopus 로고    scopus 로고
    • Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging
    • Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Murakami T, Hayashi K, Yamamoto N, Fujiwara T, Tsuchiya H, et al. Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging. Cell Cycle Georget Tex 2015; 14:1932-7; http://dx.doi.org/10.1080/15384101.2015.1033598
    • (2015) Cell Cycle Georget Tex , vol.14 , pp. 1932-1937
    • Miwa, S.1    Yano, S.2    Kimura, H.3    Yamamoto, M.4    Toneri, M.5    Murakami, T.6    Hayashi, K.7    Yamamoto, N.8    Fujiwara, T.9    Tsuchiya, H.10
  • 50
    • 0003418645 scopus 로고
    • A restriction point for control of normal animal cell proliferation
    • 4524638
    • Pardee AB. A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci U S A 1974; 71:1286-90; PMID:4524638; http://dx.doi.org/10.1073/pnas.71.4.1286
    • (1974) Proc Natl Acad Sci U S A , vol.71 , pp. 1286-1290
    • Pardee, A.B.1
  • 51
    • 0016655265 scopus 로고
    • Selective killing of transformed baby hamster kidney (BHK) cells
    • 174089
    • Pardee AB, James LJ. Selective killing of transformed baby hamster kidney (BHK) cells. Proc Natl Acad Sci U S A 1975; 72:4994-8; PMID:174089; http://dx.doi.org/10.1073/pnas.72.12.4994
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 4994-4998
    • Pardee, A.B.1    James, L.J.2
  • 52
    • 45149086183 scopus 로고    scopus 로고
    • Nongenetic Individuality in the Host–Phage Interaction
    • 18494559
    • Pearl S, Gabay C, Kishony R, Oppenheim A, Balaban NQ. Nongenetic Individuality in the Host–Phage Interaction. PLoS Biol 2008; 6:e120; PMID:18494559; http://dx.doi.org/10.1371/journal.pbio.0060120
    • (2008) PLoS Biol , vol.6 , pp. e120
    • Pearl, S.1    Gabay, C.2    Kishony, R.3    Oppenheim, A.4    Balaban, N.Q.5
  • 54
    • 0015858444 scopus 로고
    • Isolation and characterization of revertant cell lines
    • 4354072
    • Pollack R, Vogel A. Isolation and characterization of revertant cell lines. J Cell Physiol 1973; 82:93-100; PMID:4354072; http://dx.doi.org/10.1002/jcp.1040820111
    • (1973) J Cell Physiol , vol.82 , pp. 93-100
    • Pollack, R.1    Vogel, A.2
  • 55
    • 31544456409 scopus 로고    scopus 로고
    • Eradication of leukemia stem cells as a new goal of therapy in leukemia
    • 16428470
    • Ravandi F, Estrov Z. Eradication of leukemia stem cells as a new goal of therapy in leukemia. Clin Cancer Res 2006; 12:340-4; PMID:16428470; http://dx.doi.org/10.1158/1078-0432.CCR-05-1879
    • (2006) Clin Cancer Res , vol.12 , pp. 340-344
    • Ravandi, F.1    Estrov, Z.2
  • 56
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • 11689955
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414:105-11; PMID:11689955; http://dx.doi.org/10.1038/35102167
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 59
    • 40649111377 scopus 로고    scopus 로고
    • A chemical method for fast and sensitive detection of DNA synthesis in vivo
    • 18272492
    • Salic A, Mitchison TJ. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A 2008; 105:2415-20; PMID:18272492; http://dx.doi.org/10.1073/pnas.0712168105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2415-2420
    • Salic, A.1    Mitchison, T.J.2
  • 60
    • 84925831382 scopus 로고    scopus 로고
    • Lineage correlations of single cell division time as a probe of cell-cycle dynamics
    • 25762143
    • Sandler O, Mizrahi SP, Weiss N, Agam O, Simon I, Balaban NQ. Lineage correlations of single cell division time as a probe of cell-cycle dynamics. Nature 2015; 519:468-71; PMID:25762143; http://dx.doi.org/10.1038/nature14318
    • (2015) Nature , vol.519 , pp. 468-471
    • Sandler, O.1    Mizrahi, S.P.2    Weiss, N.3    Agam, O.4    Simon, I.5    Balaban, N.Q.6
  • 61
    • 0033399453 scopus 로고    scopus 로고
    • Anticancer drug targets: cell cycle and checkpoint control
    • 10606615
    • Shapiro GI, Harper JW. Anticancer drug targets:cell cycle and checkpoint control. J Clin Invest 1999; 104:1645-3; PMID:10606615; http://dx.doi.org/10.1172/JCI9054
    • (1999) J Clin Invest , vol.104 , pp. 1643-1645
    • Shapiro, G.I.1    Harper, J.W.2
  • 63
    • 84866070943 scopus 로고    scopus 로고
    • Direct observation of mammalian cell growth and size regulation
    • 22863882
    • Son S, Tzur A, Weng Y, Jorgensen P, Kim J, Kirschner MW, Manalis SR. Direct observation of mammalian cell growth and size regulation. Nat. Methods 2012; 9:910-2; PMID:22863882; http://dx.doi.org/10.1038/nmeth.2133
    • (2012) Nat. Methods , vol.9 , pp. 910-912
    • Son, S.1    Tzur, A.2    Weng, Y.3    Jorgensen, P.4    Kim, J.5    Kirschner, M.W.6    Manalis, S.R.7
  • 64
    • 66249136447 scopus 로고    scopus 로고
    • Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
    • Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 2009; 459:428–432.
    • (2009) Nature , vol.459 , pp. 428-432
    • Spencer, S.L.1    Gaudet, S.2    Albeck, J.G.3    Burke, J.M.4    Sorger, P.K.5
  • 66
    • 84884180772 scopus 로고    scopus 로고
    • Contrasting quiescent G0 phase with mitotic cell cycling in the Mouse immune system
    • 24066072
    • Tomura M, Sakaue-Sawano A, Mori Y, Takase-Utsugi M, Hata A, Ohtawa K, Kanagawa O, Miyawaki A. Contrasting quiescent G0 phase with mitotic cell cycling in the Mouse immune system. PLoS One 2013; 8:e73801; PMID:24066072; http://dx.doi.org/10.1371/journal.pone.0073801
    • (2013) PLoS One , vol.8 , pp. e73801
    • Tomura, M.1    Sakaue-Sawano, A.2    Mori, Y.3    Takase-Utsugi, M.4    Hata, A.5    Ohtawa, K.6    Kanagawa, O.7    Miyawaki, A.8
  • 68
    • 0021855166 scopus 로고
    • Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
    • 3860868
    • Zetterberg A, Larsson O. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc Natl Acad Sci U S A 1985; 82:5365-9; PMID:3860868; http://dx.doi.org/10.1073/pnas.82.16.5365
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 5365-5369
    • Zetterberg, A.1    Larsson, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.