Chromosome engineering of Escherichia coli for constitutive production of salvianic acid A

Microbial Cell Factories

Volumn 16, Issue 1, 2017, Pages

  Zhou, Liang ^a,b   Ding, Qi ^a,c   Jiang, Guo Zhen ^a,b   Liu, Zhen Ning ^a,b   Wang, Hai Yan ^a,d   Zhao, Guang Rong ^a,b  

^a TIANJIN UNIVERSITY   (China)

^b School of Pharmaceutical Science and Technology   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d Yangtze River Pharmaceutical Group Co Ltd   (China)

Author keywords

Chromosomal engineering; Constitutive promoter; Escherichia coli; Metabolic engineering; Salvianic acid A; Synthetic biology

Indexed keywords

GLUCOSE; SALVIA MILTIORRHIZA EXTRACT; SALVIANIC ACID A; TYROSINE; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLLACTIC ACID; BIOLOGICAL PRODUCT; ESCHERICHIA COLI PROTEIN; LACTIC ACID DERIVATIVE;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOSYNTHESIS; CHROMOSOME; ENZYME MECHANISM; ESCHERICHIA COLI; GENE CLUSTER; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; LACI GENE; NONHUMAN; NUPG GENE; PHEA GENE; PROMOTER REGION; PTSG GENE; PYKA GENE; PYKF GENE; SPEC GENE; TYRR GENE; BACTERIAL CHROMOSOME; BIOREACTOR; CHEMISTRY; GENETICS; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; MICROBIOLOGY; PLASMID; SALVIA;

BIOLOGICAL PRODUCTS; BIOREACTORS; BIOSYNTHETIC PATHWAYS; CHROMOSOMES, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; INDUSTRIAL MICROBIOLOGY; LACTATES; METABOLIC ENGINEERING; PLASMIDS; SALVIA;

EID: 85019385277     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-017-0700-2     Document Type: Article

References (56)

1. Zhao GR, Xiang ZJ, Ye TX, Juan YJ, Guo ZX. Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng. Food Chem. 2006;99(4):767-74.
2. Ling S, Luo R, Dai A, Guo Z, Guo R, Komesaroff PA. A pharmaceutical preparation of Salvia miltiorrhiza protects cardiac myocytes from tumor necrosis factor-induced apoptosis and reduces angiotensin II-stimulated collagen synthesis in fibroblasts. Phytomedicine. 2009;16(1):56.
3. Zhao GR, Zhang HM, Ye TX, Xiang ZJ, Yuan YJ, Guo ZX, Zhao LB. Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. Food Chem Toxicol. 2008;46(1):73-81.
4. Huang ZS, Zeng CL, Zhu LJ, Jiang L, Li N, Hu H. Salvianolic acid A inhibits platelet activation and arterial thrombosis via inhibition of phosphoinositide 3-kinase. J Thromb Haemost. 2010;8(6):1383-93.
5. Yang Y, Han Z, Wang Y, Wang L, Pan S, Liang S, Wang S. Plasma metabonomic analysis reveals the effects of salvianic acid on alleviating acute alcoholic liver damage. RSC Adv. 2015;5(46):36732-41.
6. Song Q, Chu X, Zhang X, Bao Y, Zhang Y, Guo H, Liu Y, Liu H, Zhang J, Zhang Y. Mechanisms underlying the cardioprotective effect of salvianic acid A against isoproterenol-induced myocardial ischemia injury in rats: possible involvement of L-type calcium channels and myocardial contractility. J Ethnopharmacol. 2016;189:157-64.
7. Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2006;45(12):1345-59.
8. Erkan N, Ayranci G, Ayranci E. Antioxidant activities of rosemary (Rosmarinus Officinalis L.) extract, blackseed (Nigella sativa L.) essential oil, carnosic acid, rosmarinic acid and sesamol. Food Chem. 2008;110(1):76.
9. Pan LL, Wang J, Jia YL, Zheng HM, Wang Y, Zhu YZ. Asymmetric synthesis and evaluation of danshensu-cysteine conjugates as novel potential anti-apoptotic drug candidates. Int J Mol Sci. 2015;16(1):628-44.
10. Lam FF, Yeung JH, Chan KM, Or PM. Relaxant effects of danshen aqueous extract and its constituent danshensu on rat coronary artery are mediated by inhibition of calcium channels. Vasc Pharmacol. 2007;46(4):271-7.
11. 4-catalyzed asymmetric dihydroxylation. Tetrahedron: Asymmetry. 2004;15(19):3111-6.
12. Yao YF, Wang CS, Qiao J, Zhao GR. Metabolic engineering of Escherichia coli for production of salvianic acid A via an artificial biosynthetic pathway. Metab Eng. 2013;19(5):79.
13. Bai CL, Zhao GR. Separation of salvianic acid A from the fermentation broth of engineered Escherichia coli using macroporous resins. J Sep Sci. 2015;38(16):2833-40.
14. Friehs K. Plasmid copy number and plasmid stability. Adv Biochem Eng Biot. 2004;86:47-82.
15. Blazeck J, Alper HS. Promoter engineering: recent advances in controlling transcription at the most fundamental level. Biotechnol J. 2013;8(1):46.
16. Matsuda F, Ishii J, Kondo T, Ida K, Tezuka H, Kondo A. Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance. Microb Cell Fact. 2013;12(1):1-11.
17. Jong BWD, Shi S, Siewers V, Nielsen J. Improved production of fatty acid ethyl esters in Saccharomyces cerevisiae through up-regulation of the ethanol degradation pathway and expression of the heterologous phosphoketolase pathway. Microb Cell Fact. 2014;13(1):39.
18. Borodina I, Kildegaard KR, Jensen NB, Blicher TH, Maury J, Sherstyk S, Schneider K, Lamosa P, Herrgård MJ, Rosenstand I. Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine. Metab Eng. 2015;27:57-64.
19. Sun J, Shao Z, Zhao H, Nair N, Wen F, Xu JH, Zhao H. Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae. Biotechnol Bioeng. 2012;109(8):2082.
20. Dai Z, Liu Y, Zhang X, Shi M, Wang B, Wang D, Huang L, Zhang X. Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides. Metab Eng. 2013;20(5):146-56.
21. Galanie S, Smolke CD. Optimization of yeast-based production of medicinal protoberberine alkaloids. Microb Cell Fact. 2015;14(1):144.
22. Brown S, Clastre M, Courdavault V, O'Connor SE. De novo production of the plant-derived alkaloid strictosidine in yeast. Proc Natl Acad Sci USA. 2015;112(11):3205.
23. Lim CG, Fowler ZL, Hueller T, Schaffer S, Koffas MAG. High-yield resveratrol production in engineered Escherichia coli. Appl Environ Microbiol. 2011;77(10):3451-60.
24. Alper H, Fischer C, Nevoigt E, Stephanopoulos G. Tuning genetic control through promoter engineering. Proc Natl Acad Sci USA. 2005;102(36):12678-83.
25. Tong YJ, Ji XJ, Shen MQ, Liu LG, Nie ZK, Huang H. Constructing a synthetic constitutive metabolic pathway in Escherichia coli for (R, R)-2,3-butanediol production. Appl Microbiol Biotechnol. 2016;100(2):637.
26. Menezes AC, Suzuki MF, Oliveira JE, Ribela MT, Furigo IC Jr, Donato J, Bartolini P, Soares CR. Expression, purification and characterization of the authentic form of human growth hormone receptor antagonist G120R-hGH obtained in Escherichia coli periplasmic space. Protein Expr Purif. 2016;131:91.
27. Paddon CJ, Westfall PJ, Pitera DJ, Benjamin K, Fisher K, Mcphee D, Leavell MD, Tai A, Main A, Eng D. High-level semi-synthetic production of the potent antimalarial artemisinin. Nature. 2013;496(7446):528-32.
28. Chen Y, Xiao W, Wang Y, Liu H, Li X, Yuan Y. Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering. Microb Cell Fact. 2016;15(1):1-13.
29. Lemuth K, Steuer K, Albermann C. Engineering of a plasmid-free Escherichia coli strain for improved in vivo biosynthesis of astaxanthin. Microb Cell Fact. 2011;10(1):1-12.
30. Cui YY, Chen L, Zhang YY, Jian H, Liu JZ. Production of shikimic acid from Escherichia coli through chemically inducible chromosomal evolution and cofactor metabolic engineering. Microb Cell Fact. 2014;13(1):21.
31. Li Y, Lin Z, Huang C, Zhang Y, Wang Z, Tang YJ, Chen T, Zhao X. Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing. Metab Eng. 2015;31:13-21.
32. Datsenko KA, Wanner BL. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA. 2000;97(12):6640-5.
33. Neidhardt FC, Bloch PL, Smith DF. Culture medium for enterobacteria. J Bacteriol. 1974;119(3):736-47.
34. Gosset G. Production of aromatic compounds in bacteria. Curr Opin Biotechnol. 2009;20(20):651-8.
35. Patnaik R, Zolandz RR, Green DA, Kraynie DF. l-Tyrosine production by recombinant Escherichia coli: fermentation optimization and recovery. Biotechnol Bioeng. 2008;99(4):741-52.
36. Rodriguez A, Martínez JA, Flores N, Escalante A, Gosset G, Bolivar F. Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds. Microb Cell Fact. 2014;13(1):126.
37. Lütkeeversloh T, Stephanopoulos G. Combinatorial pathway analysis for improved l-tyrosine production in Escherichia coli: identification of enzymatic bottlenecks by systematic gene overexpression. Metab Eng. 2008;10(2):69-77.
38. Santos CN, Xiao W, Stephanopoulos G. Rational, combinatorial, and genomic approaches for engineering l-tyrosine production in Escherichia coli. Proc Natl Acad Sci USA. 2012;109(34):13538-43.
39. Juminaga D, Baidoo EE, Reddingjohanson AM, Batth TS, Burd H, Mukhopadhyay A, Petzold CJ, Keasling JD. Modular engineering of l-tyrosine production in Escherichia coli. Appl Environ Microbiol. 2012;78(1):89-98.
40. Kang SY, Choi O, Lee JK, Ahn JO, Ahn JS, Hwang BY, Hong YS. Artificial de novo biosynthesis of hydroxystyrene derivatives in a tyrosine overproducing Escherichia coli strain. Microb Cell Fact. 2015;14(1):78.
41. Díaz E, Ferrández A, Prieto MA, García JL. Biodegradation of aromatic compounds by Escherichia coli. Microbiol Mol Biol Rev. 2001;65(65):523-69.
42. Dvorak P, Chrast L, Nikel PI, Fedr R, Soucek K, Sedlackova M, Chaloupkova R, Lorenzo VD, Prokop Z, Damborsky J. Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway. Microb Cell Fact. 2015;14(1):201.
43. Kim SC, Min BE, Hwang HG, Sang WS, Jung GY. Pathway optimization by re-design of untranslated regions for l-tyrosine production in Escherichia coli. Sci Rep. 2014;5(1):13853.
44. Lim JH, Seo SW, Kim SY, Jung GY. Model-driven rebalancing of the intracellular redox state for optimization of a heterologous n-butanol pathway in Escherichia coli. Metab Eng. 2013;20(5):56-62.
45. Kwak DH, Lim HG, Yang J, Seo SW, Jung GY. Synthetic redesign of Escherichia coli for cadaverine production from galactose. Biotechnol Biofuels. 2017;10(1):20.
46. Boer HAD, Comstock LJ, Vasser M. The tac promoter: a functional hybrid derived from the trp and lac promoters. Proc Natl Acad Sci USA. 1983;80(1):21-5.
47. Lu W, Shi Y, He S, Fei Y, Yu K, Yu H. Enhanced production of CoQ 10 by constitutive overexpression of 3-demethyl ubiquinone-9 3-methyltransferase under tac promoter in Rhodobacter sphaeroides. Biochem Eng J. 2013;72:42-7.
48. Aghaabdollahian S, Rabbani M, Ghaedi K. Sadeghi HMM. Molecular cloning of Reteplase and its expression in E. coli using tac promoter. Adv Biomed Res. 2014;3:190.
49. Seo SW, Yang JS, Kim I, Yang J, Min BE, Kim S, Jung GY. Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency. Metab Eng. 2013;15(1):67.
50. Muñoz AJ, Hernández-Chávez G, Anda RD, Martínez A, Bolívar F, Gosset G. Metabolic engineering of l-3,4-dihydroxyphenylalanine (l-DOPA) synthesis from glucose. J Ind Microbiol Biotechnol. 2011;38(11):1845-52.
51. Maeda M, Shimada T, Ishihama A. Strength and regulation of seven rRNA promoters in Escherichia coli. PLoS ONE. 2015;10(12):e0144697.
52. Wu H, Wang H, Chen J, Chen GQ. Effects of cascaded vgb promoters on poly(hydroxybutyrate) (PHB) synthesis by recombinant Escherichia coli grown micro-aerobically. Appl Microbiol Biotechnol. 2014;98(24):10013-21.
53. Li M, Wang J, Geng Y, Li Y, Qian W, Liang Q, Qi Q. A strategy of gene overexpression based on tandem repetitive promoters in Escherichia coli. Microb Cell Fact. 2012;11(1):19.
54. Bryant JA, Sellars LE, Busby SJ, Lee DJ. Chromosome position effects on gene expression in Escherichia coli K-12. Nucleic Acids Res. 2014;42(18):11383-92.
55. De Hollander JA. Kinetics of microbial product formation and its consequences for the optimization of fermentation processes. Antonie Van Leeuwenhoek. 1993;63(3):375.
56. Tyo KEJ, Ajikumar PK, Stephanopoulos G. Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat Biotechnol. 2009;27(8):760-5.