Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B

Food and Chemical Toxicology

Volumn 46, Issue 1, 2008, Pages 73-81

  Zhao, Guang Rong ^a   Zhang, Heng Ming ^a   Ye, Ting Xiang ^a   Xiang, Zhi Jun ^a   Yuan, Ying Jin ^a   Guo, Zhi Xin ^b   Zhao, Li Bin ^b  

^a TIANJIN UNIVERSITY   (China)

^b Tianjin Tasly Group Co Ltd   (China)

Author keywords

ABTS radical; Antioxidant; Danshensu; DPPH; Human vein vascular endothelial cells; Phenolic; Radical scavenging; Salvianolic acid B; Structure activity relationship; Vitamin C equivalent capacity

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; ASCORBIC ACID; CAFFEIC ACID; FERROUS ION; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON CHELATING AGENT; PHENOL DERIVATIVE; SALVIANOLIC ACID B; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CONJUGATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PLANT ROOT; POLYMERIZATION; SALVIA MILTIORRHIZA; STRUCTURE ACTIVITY RELATION; VASCULAR ENDOTHELIUM;

ANTIOXIDANTS; ASCORBIC ACID; BENZOFURANS; BENZOTHIAZOLES; CELL SURVIVAL; CHELATING AGENTS; ENDOTHELIAL CELLS; FERROUS COMPOUNDS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LACTATES; OXIDANTS; PICRATES; PLANT ROOTS; SALVIA; SULFONIC ACIDS; TETRAZOLIUM SALTS; THIAZOLES;

SALVIA MILTIORRHIZA;

EID: 36848999824     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.06.034     Document Type: Article

References (41)

1. Chan K., Chui S.H., Wong D.Y., Ha W.Y., Chan C.L., and Wong R.N. Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction. Life Science 75 (2004) 3157-3171
2. Chen C.P., Yokozawa T., and Chung H.Y. Inhibitor effect of caffeic acid analogs isolated from Salviae miltiorrhizae radix against 1,1-diphenyl-2-picrylhydrazyl radical. Experimental and Toxilogical Pathology 51 (1999) 59-63
3. 2+ or ultraviolet light. Journal of American Oil Chemistry Society 75 (1998) 1717-1721
4. Chen Y.H., Du G.H., and Zhang J.T. Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats. Acta Pharmacologica Sinica 21 (2000) 463-466
5. Chen Y.H., Lin S.J., Ku H.H., Shiao M.S., Lin F.Y., Chen J.W., and Chen Y.L. Salvianolic Acid B Attenuates VCAM-1 and ICAM-1 Expression in TNF-a-Treated Human Aortic Endothelial Cells. Journal of Cellular Biochemistry 82 (2001) 512-521
6. Chung Y.C., Chen S.J., Hsu C.K., Chang C.T., and Chou S.T. Studies on the antioxidant activity of Graptopetalum paraguayense E Walther. Food Chemistry 91 (2005) 419-424
7. Ding M., Zhao G.R., Yuan Y.J., and Guo Z.X. Aqueous extract of Salvia miltiorrhoza regulates adhesion molecules expression of tumor necrosis factor-induced endothelial cells by blocking activation of nuclear factor kappa B. Journal of Cardiovascular Pharmacology 45 (2005) 516-524
8. Ding M., Ye T.X., Zhao G.R., Yuan Y.J., and Guo Z.X. Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha. International Immunopharmacology 5 (2005) 1641-1651
9. Dinis T.C.P., Madeira V.M.C., and Almeidam L.M. Action of phenolic derivates (acetoaminophen, salycilate, and 5-aminosalycilate) as inhibitors of membrane lipid peroxidation and peroxyl radical scavengers. Archives of Biochemistry and Biophysics 315 (1994) 161-169
10. Du G.H., Qiu Y., and Zhang J.T. Salvianolic acid B protects the memory functions against transient cerebral ischemia in mice. Journal of Asian Natural Product Research 2 (2000) 145-152
11. Fung K.P., Wu J., Zeng L.H., Wong H.N., Lee C.M., Hon P.M., Chang H.M., and Wu T.W. Lithospermic acid B as an antioxidant-based protector of cultured ventricular myocytes and aortic endothelial cells of rabbits. Life Science 53 (1993) 189-193
12. Gulcin I. Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid). Toxicology 217 (2006) 213-220
13. Halliwell B. Annual review, antioxidants in human health and disease. Nutrition 16 (1996) 33-50
14. Hase K., Kasimu R., Basnet P., Kadota S., and Namba T. Preventive effect of lithospermate B from Salvia miltiorhiza on experimental hepatitis induced by carbon tetrachloride or d-galactosamine/lipopolysaccharide. Planta Medica 63 (1997) 22-26
15. Hu P., Luo G.A., Zhao Z., and Jiang Z.H. Quality assessment of radix Salviae miltiorrhizae. Chemical and Pharmaceutical Bulletin 53 (2005) 481-486
16. Huang Y.S., and Zhang J.T. Antioxidant effect of three water-soluble components isolated from Salvia miltiorrhiza in vitro. Acta Pharmacologica Sinica 27 (1992) 96-100
17. Jiang R.W., Lau K.M., Hon P.M., Mak T.C.W., Woo K.S., and Fung K.P. Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza. Current Medicinal Chemistry 12 (2005) 237-246
18. Kim D.-O., and Lee C.Y. Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship. Critical Reviews in Food Science and Nutrition 44 (2004) 253-273
19. Kim D.-O., Lee K.W., Lee H.J., and Lee C.Y. Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. Journal of Agricultural and Food Chemistry 50 (2002) 3713-3717
20. Lee G.T., Ha H., Jung M., Li H., Hong S.W., Cha B.S., Lee H.C., and Cho Y.D. Delayed treatment with lithospermate B attenuates experimental diabetic renal injury. Journal of the American Society of Nephrology 14 (2003) 709-720
21. Li D.Y., Xu L.N., and Liu X.G. Effects of water-soluble components isolated from Salvia miltiorrhiza on oxygen free radical generation and lipid peroxidation. Journal of Chinese Pharmaceutical Sciences 4 (1995) 107-112
22. Li L.N. Biologically active components from traditional Chinese medicines. Pure Applied Chemistry 70 (1998) 547-554
23. Liu F., Ooi V.E.C., and Chang S.T. Free radical scavenging activity of mushroom polysaccharide extracts. Life Science 60 (1997) 763-771
24. Liu G.T., Zhang T.M., Wang B.E., and Wang Y.W. Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes. Biochemical Pharmacology 43 (1992) 147-152
25. Lu Y., and Foo Y.L. Polyphenolics of Salvia - a review. Phytochemistry 59 (2002) 117-140
26. Meerson F.Z., Kagan V.E., Kozlov Y.P., Belkina L.M., and Arkhipenko Y.V. The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart. Basic Research in Cardiology 77 (1982) 465-485
27. Nordberg J., and Arner E.S.J. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radical and Biological Medicine 31 (2001) 1287-1312
28. Pan J., and Xu T. Preparative separation of D (+) - (3,4-dihydrophenyl)-lactate sodium from Salviamiltirrhiza by HPLC. Chinese Traditional and Herbal Drugs 34 (2003) 125-127
29. Qui Y., Rui Y.C., Zhang L., Li T.J., and Zhang W.D. VEGF induced hyperpermeability in bovine aortic endothelial cell and inhibitory effect of salvianolic acid B. Acta Pharmacologica Sinica 22 (2001) 117-120
30. Ren D., Du G., and Zhang J. Effects of salvianolic acids on endothelial cells against damage induced by cholestane-3beta-5alpha-6beta-triol. Chinese Medicinal Journal 116 (2003) 630-632
31. Shahidi F., and Wanasundara P.K. Phenolic antioxidants. Critical Reviews in Food Science and Nutrition 32 (1992) 67-103
32. Wang X.J., Wang Z.B., and Xu J.X. Effect of salvianic acid A on lipid peroxidation and membrane permeability in mitochondria. Journal of Ethnopharmacology 97 (2005) 441-445
33. +-induced cytotoxicity. Neuroscience Research 51 (2005) 129-138
34. Willcox J.K., Ash S.L., and Catignani G.L. Antioxidants and prevention of chronic disease. Critical Review in Food Science and Nutrition 44 (2004) 275-295
35. Wu X.J., Wang Y.P., Wang W., Sun W.K., Xu Y.M., and Xuan L.J. Free radical scavenging and inhibition of lipid peroxidation by magnesium lithospermate B. Acta Pharmacologica Sinica 21 (2000) 855-888
36. Yokozawa T., Chung H.Y., Dong E., and Oura H. Confirmation that magnesium lithospermate B has a hydroxyl radical-scavenging action. Experimental and Toxicologic Pathology 47 (1995) 341-344
37. Yokozawa T., Dong E., Oura H., Nonaka G., and Nishioka I. Magnesium lithospermate B ameliorates cisplatin-induced injury in cultured renal epithelial cells. Experimental and Toxicologic Pathology 49 (1997) 343-346
38. Yu W., Zhao Y., and Shu B. The radical scavenging activities of radix puerariae isoflavonoids: a chemiluminescence study. Food Chemistry 86 (2004) 525-529
39. Yuan Y.V., Bone D.E., and Carrington M.F. Antioxidant activity of dulse (Palmaria palmata) extract evaluated in vitro. Food Chemistry 91 (2005) 485-494
40. Zhao G.R., Xiang Z.J., Ye T.X., Yuan Y.J., and Guo Z.X. Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng. Food Chemistry 99 (2006) 676-774
41. Zhou Z., Liu Y., Miao A.D., and Wang S.Q. Salvianolic acid B attenuates plasminogen activator inhibitor type 1 production in TNF-a treated human umbilical vein endothelial cells. Journal of Cellular Biochemistry 96 (2005) 109-116