Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine

Metabolic Engineering

Volumn 27, Issue , 2015, Pages 57-64

  Borodina, Irina ^a   Kildegaard, Kanchana R ^a   Jensen, Niels B ^a   Blicher, Thomas H ^b   Maury, JérÔme ^a   Sherstyk, Svetlana ^a   Schneider, Konstantin ^a   Lamosa, Pedro ^c   Herrgård, Markus J ^a   Rosenstand, Inger ^a   Öberg, Fredrik ^a   Forster, Jochen ^a   Nielsen, Jens ^a,d  

^a Chalmers University of Technology   (Denmark)

^b University of Copenhagen   (Denmark)

^c INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^d CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

3 hydroxypropionic acid; Biosustainable acrylics; Saccharomyces cerevisiae; alanine; alanine pyruvate aminotransferase

Indexed keywords

ACRYLICS; AMINO ACIDS; BACILLUS CEREUS; BACTERIOLOGY; BIOCHEMISTRY; BIOSYNTHESIS; CARBON DIOXIDE; FERMENTATION;

3-HYDROXYPROPIONIC ACID; AMINOTRANSFERASE; CHEMICAL BUILDING BLOCKS; FED-BATCH FERMENTATION; HIGH-LEVEL PRODUCTION; MICROBIAL FERMENTATION; SUPERABSORBENT POLYMER; SUSTAINABLE PRODUCTION;

YEAST;

BETA ALANINE; BETA ALANINE PYRUVATE AMINOTRANSFERASE; GLUCOSE; HYDRACRYLIC ACID; BACTERIAL PROTEINS; BETA-ALANINE; BETA-ALANINE-PYRUVATE TRANSAMINASE; LACTIC ACID;

AMINO ACID SYNTHESIS; ARTICLE; BACILLUS CEREUS; FED BATCH FERMENTATION; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; SACCHAROMYCES CEREVISIAE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; METABOLIC ENGINEERING; METABOLISM;

BACILLUS CEREUS; BACTERIAL PROTEINS; BETA-ALANINE; BETA-ALANINE-PYRUVATE TRANSAMINASE; LACTIC ACID; METABOLIC ENGINEERING; SACCHAROMYCES CEREVISIAE;

EID: 84909594451     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.10.003     Document Type: Article

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