De novo production of the plant-derived alkaloid strictosidine in yeast

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 11, 2015, Pages 3205-3210

  Brown, Stephanie ^a   Clastre, Marc ^b   Courdavault, Vincent ^b   O'Connor, Sarah E ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b UNIVERSITÉ DE TOURS   (France)

Author keywords

Catharanthus roseus; Monoterpene indole alkaloid; Saccharomyces cerevisiae; Secologanin; Strictosidine

Indexed keywords

CYTOCHROME P450; GERANIOL; INDOLE ALKALOID; LOGANIN; MONOTERPENE INDOLE ALKALOID; STRICTOSIDINE; TERPENE; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; VINCA ALKALOID;

ARTICLE; BIOSYNTHESIS; BIOTECHNOLOGICAL PRODUCTION; CELL COMPARTMENTALIZATION; DIASTEREOISOMER; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC ENGINEERING; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SECONDARY METABOLISM; SIGNAL TRANSDUCTION; CHEMISTRY; ENZYMOLOGY; MASS SPECTROMETRY; METABOLISM; PLANT;

CATHARANTHUS ROSEUS; SACCHAROMYCES CEREVISIAE;

ALCOHOL DEHYDROGENASE; BIOSYNTHETIC PATHWAYS; CHROMATOGRAPHY, LIQUID; GENETIC ENGINEERING; MASS SPECTROMETRY; PLANTS; SACCHAROMYCES CEREVISIAE; VINCA ALKALOIDS;

EID: 84925244299     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1423555112     Document Type: Article

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