3D Culture as a Clinically Relevant Model for Personalized Medicine

SLAS Technology

Volumn 22, Issue 3, 2017, Pages 245-253

  Fong, Eliza Li Shan ^a   Toh, Tan Boon ^b   Yu, Hanry ^a,c,d,e,f   Chow, Edward Kai Hua ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c AGENCY FOR SCIENCE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

3D; high content screening; personalized medicine; spheroids; tumor models

Indexed keywords

DISEASES; TUMORS;

FUNDAMENTAL MECHANISMS; HIGH-CONTENT SCREENING; PERSONALIZED MEDICINES; SPHEROIDS; TARGETED THERAPEUTICS; THREEDIMENSIONAL (3-D); TUMOR HETEROGENEITY; TUMOR MODELS;

DIAGNOSIS;

ANAPLASTIC LYMPHOMA KINASE INHIBITOR; EPIRUBICIN; FLUOROURACIL; GELATIN; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE; NOGGIN; PACLITAXEL; PROSTAGLANDIN E2; TIRAPAZAMINE; VINORELBINE TARTRATE; ANTINEOPLASTIC AGENT;

BREAST CANCER; CANCER GROWTH; CANCER PATIENT; CANCER RESEARCH; CELL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; EVALUATION AND FOLLOW UP; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC HETEROGENEITY; GENOTYPE PHENOTYPE CORRELATION; HEALTH CARE PLANNING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEL; MICROFLUIDIC ANALYSIS; MOLECULARLY TARGETED THERAPY; OUTCOME ASSESSMENT; PERSONALIZED MEDICINE; REVIEW; SEQUENCE ANALYSIS; SOLID MALIGNANT NEOPLASM; SPHEROID CELL; THREE DIMENSIONAL IMAGING; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; DRUG SCREENING; ISOLATION AND PURIFICATION; MASS SCREENING; ORGAN CULTURE TECHNIQUE; PROCEDURES;

ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MASS SCREENING; ORGAN CULTURE TECHNIQUES; PRECISION MEDICINE;

EID: 85019372737     PISSN: 24726303     EISSN: 24726311     Source Type: Journal    
DOI: 10.1177/2472630317697251     Document Type: Review

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