-
1
-
-
84975275212
-
Modeling development and disease with organoids
-
Clevers, H. Modeling development and disease with organoids. Cell 165, 1586-1597 (2016).
-
(2016)
Cell
, vol.165
, pp. 1586-1597
-
-
Clevers, H.1
-
2
-
-
84904396621
-
Organogenesis in a dish: Modeling development and disease using organoid technologies
-
Lancaster, M. A. & Knoblich, J. A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125 (2014).
-
(2014)
Science
, vol.345
, pp. 1247125
-
-
Lancaster, M.A.1
Knoblich, J.A.2
-
3
-
-
84872534651
-
Cytosystems dynamics in self-organization of tissue architecture
-
Sasai, Y. Cytosystems dynamics in self-organization of tissue architecture. Nature 493, 318-326 (2013).
-
(2013)
Nature
, vol.493
, pp. 318-326
-
-
Sasai, Y.1
-
4
-
-
84959357347
-
Organoids as an in vitro model of human development and disease
-
Fatehullah, A., Tan, S. H. & Barker, N. Organoids as an in vitro model of human development and disease. Nat. Cell Biol. 18, 246-254 (2016).
-
(2016)
Nat. Cell Biol
, vol.18
, pp. 246-254
-
-
Fatehullah, A.1
Tan, S.H.2
Barker, N.3
-
5
-
-
70849130059
-
Designing materials to direct stem-cell fate
-
Lutolf, M. P., Gilbert, P. M. & Blau, H. M. Designing materials to direct stem-cell fate. Nature 462, 433-441 (2009).
-
(2009)
Nature
, vol.462
, pp. 433-441
-
-
Lutolf, M.P.1
Gilbert, P.M.2
Blau, H.M.3
-
6
-
-
84904497709
-
3D niche microarrays for systems-level analyses of cell fate
-
Ranga, A. et al. 3D niche microarrays for systems-level analyses of cell fate. Nat. Commun. 5, 4324 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 4324
-
-
Ranga, A.1
-
7
-
-
84878760040
-
Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications
-
Sato, T. & Clevers, H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190-1194 (2013).
-
(2013)
Science
, vol.340
, pp. 1190-1194
-
-
Sato, T.1
Clevers, H.2
-
8
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009)
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
-
9
-
-
84880292828
-
A functional CFTR assay using primary cystic fibrosis intestinal organoids
-
Dekkers, J. F. et al. A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nat. Med. 19, 939-945 (2013).
-
(2013)
Nat. Med
, vol.19
, pp. 939-945
-
-
Dekkers, J.F.1
-
10
-
-
84862777784
-
Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
-
Yui, S. et al. Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell. Nat. Med. 18, 618-623 (2012).
-
(2012)
Nat. Med
, vol.18
, pp. 618-623
-
-
Yui, S.1
-
11
-
-
23744449992
-
Matrigel: Basement membrane matrix with biological activity
-
Kleinman, H. K. & Martin, G. R. Matrigel: basement membrane matrix with biological activity. Semin. Cancer Biol. 15, 378-386 (2005).
-
(2005)
Semin. Cancer Biol
, vol.15
, pp. 378-386
-
-
Kleinman, H.K.1
Martin, G.R.2
-
12
-
-
84907164587
-
Type i collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium
-
Jabaji, Z. et al. Type I collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium. PLoS One 9, e107814 (2014).
-
(2014)
PLoS One
, vol.9
, pp. e107814
-
-
Jabaji, Z.1
-
13
-
-
77956399506
-
Matrigel: A complex protein mixture required for optimal growth of cell culture
-
Hughes, C. S., Postovit, L. M. & Lajoie, G. A. Matrigel: a complex protein mixture required for optimal growth of cell culture. Proteomics 10, 1886-1890 (2010).
-
(2010)
Proteomics
, vol.10
, pp. 1886-1890
-
-
Hughes, C.S.1
Postovit, L.M.2
Lajoie, G.A.3
-
14
-
-
0026701412
-
Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components
-
Vukicevic, S. et al. Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components. Exp. Cell Res. 202, 1-8 (1992).
-
(1992)
Exp. Cell Res
, vol.202
, pp. 1-8
-
-
Vukicevic, S.1
-
15
-
-
84861714640
-
Designing cell-compatible hydrogels for biomedical applications
-
Seliktar, D. Designing cell-compatible hydrogels for biomedical applications. Science 336, 1124-1128 (2012).
-
(2012)
Science
, vol.336
, pp. 1124-1128
-
-
Seliktar, D.1
-
16
-
-
35548972427
-
Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions
-
Ehrbar, M. et al. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules 8, 3000-3007 (2007).
-
(2007)
Biomacromolecules
, vol.8
, pp. 3000-3007
-
-
Ehrbar, M.1
-
17
-
-
84877921898
-
RGD-dependent epithelial cell-matrix interactions in the human intestinal crypt
-
Benoit, Y. D., Groulx, J. F., Gagné, D. & Beaulieu, J. F. RGD-dependent epithelial cell-matrix interactions in the human intestinal crypt. J. Signal Transduct. 2012, 248759 (2012).
-
(2012)
J. Signal Transduct
, vol.2012
, pp. 248759
-
-
Benoit, Y.D.1
Groulx, J.F.2
Gagné, D.3
Beaulieu, J.F.4
-
18
-
-
0025825189
-
Changes in the expression of laminin during intestinal development
-
Simo, P. et al. Changes in the expression of laminin during intestinal development. Development 112, 477-487 (1991).
-
(1991)
Development
, vol.112
, pp. 477-487
-
-
Simo, P.1
-
19
-
-
0028129795
-
Differential expression of laminin isoforms and 6- 4 integrin subunits in the developing human and mouse intestine
-
Simon-Assmann, P. et al. Differential expression of laminin isoforms and 6- 4 integrin subunits in the developing human and mouse intestine. Dev. Dyn. 201, 71-85 (1994).
-
(1994)
Dev. Dyn
, vol.201
, pp. 71-85
-
-
Simon-Assmann, P.1
-
20
-
-
84880558928
-
Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay
-
Wang, F. et al. Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay. Gastroenterology 145, 383-395 (2013).
-
(2013)
Gastroenterology
, vol.145
, pp. 383-395
-
-
Wang, F.1
-
21
-
-
84880983340
-
Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/-catenin signaling
-
Yamamoto, S. et al. Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/-catenin signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 305, G241-G249 (2013).
-
(2013)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.305
, pp. G241-G249
-
-
Yamamoto, S.1
-
22
-
-
84938494049
-
Mechanical induction of the tumorigenic -catenin pathway by tumour growth pressure
-
Fernández-Sánchez, M. E. et al. Mechanical induction of the tumorigenic -catenin pathway by tumour growth pressure. Nature 523, 92-95 (2015).
-
(2015)
Nature
, vol.523
, pp. 92-95
-
-
Fernández-Sánchez, M.E.1
-
23
-
-
67649195858
-
Control of stem cell fate by physical interactions with the extracellular matrix
-
Guilak, F. et al. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell 5, 17-26 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, pp. 17-26
-
-
Guilak, F.1
-
24
-
-
84945892538
-
Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer
-
Gregorieff, A., Liu, Y., Inanlou, M. R., Khomchuk, Y. & Wrana, J. L. Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer. Nature 526, 715-718 (2015).
-
(2015)
Nature
, vol.526
, pp. 715-718
-
-
Gregorieff, A.1
Liu, Y.2
Inanlou, M.R.3
Khomchuk, Y.4
Wrana, J.L.5
-
25
-
-
85018698979
-
Dual role of YAP and TAZ in renewal of the intestinal epithelium
-
Imajo, M., Ebisuya, M. & Nishida, E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat. Cell Biol. 17, 7-19 (2015).
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 7-19
-
-
Imajo, M.1
Ebisuya, M.2
Nishida, E.3
-
26
-
-
84883466306
-
A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
-
Aragona, M. et al. A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell 154, 1047-1059 (2013).
-
(2013)
Cell
, vol.154
, pp. 1047-1059
-
-
Aragona, M.1
-
27
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont, S. et al. Role of YAP/TAZ in mechanotransduction. Nature 474, 179-183 (2011).
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
-
28
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht, M. D. & Werb, Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17, 463-516 (2001).
-
(2001)
Annu. Rev. Cell Dev. Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
29
-
-
84865411430
-
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
-
Halder, G., Dupont, S. & Piccolo, S. Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 13, 591-600 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 591-600
-
-
Halder, G.1
Dupont, S.2
Piccolo, S.3
-
30
-
-
45249104205
-
Cell encapsulation in biodegradable hydrogels for tissue engineering applications
-
Nicodemus, G. D. & Bryant, S. J. Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng. Part B Rev. 14, 149-165 (2008).
-
(2008)
Tissue Eng. Part B Rev
, vol.14
, pp. 149-165
-
-
Nicodemus, G.D.1
Bryant, S.J.2
-
31
-
-
84924422753
-
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids
-
Matano, M. et al. Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids. Nat. Med. 21, 256-262 (2015).
-
(2015)
Nat. Med
, vol.21
, pp. 256-262
-
-
Matano, M.1
-
32
-
-
80054857419
-
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
-
Sato, T. et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 141, 1762-1772 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
-
33
-
-
84871809302
-
STAR: Ultrafast universal RNA-seq aligner
-
Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
Dobin, A.2
-
34
-
-
84928987900
-
HTSeq-A Python framework to work with high-throughput sequencing data
-
Anders, S., Pyl, P. T. & Huber, W. HTSeq-a Python framework to work with high-throughput sequencing data. Bioinformatics 31, 166-169 (2015).
-
(2015)
Bioinformatics
, vol.31
, pp. 166-169
-
-
Anders, S.1
Pyl, P.T.2
Huber, W.3
-
35
-
-
84865074382
-
RSeQC: Quality control of RNA-seq experiments
-
Wang, L., Wang, S. & Li, W. RSeQC: quality control of RNA-seq experiments. Bioinformatics 28, 2184-2185 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 2184-2185
-
-
Wang, L.1
Wang, S.2
Li, W.3
-
36
-
-
79961123152
-
RSEM: Accurate transcript quantification from RNA-Seq data with or without a reference genome
-
Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12, 323 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 323
-
-
Li, B.1
Dewey, C.N.2
-
37
-
-
75249087100
-
EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
38
-
-
84896735766
-
Voom: Precision weights unlock linear model analysis tools for RNA-seq read counts
-
Law, C. W., Chen, Y., Shi, W. & Smyth, G. K. voom: Precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol. 15, R29 (2014).
-
(2014)
Genome Biol
, vol.15
, pp. R29
-
-
Law, C.W.1
Chen, Y.2
Shi, W.3
Smyth, G.K.4
-
39
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
-
(2015)
Nucleic Acids Res
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
-
40
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
41
-
-
84877619075
-
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
-
Sadanandam, A. et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat. Med. 19, 619-625 (2013).
-
(2013)
Nat. Med
, vol.19
, pp. 619-625
-
-
Sadanandam, A.1
-
42
-
-
0029100640
-
Identification of cell binding sites in the laminin 1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides
-
Nomizu, M. et al. Identification of cell binding sites in the laminin 1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides. J. Biol. Chem. 270, 20583-20590 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 20583-20590
-
-
Nomizu, M.1
-
43
-
-
14444274331
-
Cell binding sequences in mouse laminin 1 chain
-
Nomizu, M. et al. Cell binding sequences in mouse laminin 1 chain. J. Biol. Chem. 273, 32491-32499 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32491-32499
-
-
Nomizu, M.1
|