메뉴 건너뛰기




Volumn 75, Issue 15, 2015, Pages 2963-2968

Maintaining tumor heterogeneity in patient-derived tumor xenografts

Author keywords

[No Author keywords available]

Indexed keywords

BASIC RESEARCH; CANCER GROWTH; CELL HETEROGENEITY; EX VIVO STUDY; GENETIC HETEROGENEITY; GENOMICS; HUMAN; IN VIVO STUDY; NONHUMAN; PATIENT DERIVED TUMOR XENOGRAFT; PRIORITY JOURNAL; REVIEW; STROMA; TRANSLATIONAL RESEARCH; TREATMENT RESPONSE; TUMOR HETEROGENEITY; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; ANIMAL; DISEASE MODEL; DRUG SCREENING; EXPERIMENTAL NEOPLASM; MOUSE; PATHOLOGY; XENOGRAFT;

EID: 84942866389     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-0727     Document Type: Review
Times cited : (274)

References (33)
  • 1
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and trans criptomic architecture of 2,000 breast tumours reveals novel subgroups
    • Curtis C, Shah SP, Chin S-F, Turashvili G, Rueda OM, Dunning MJ, et al. The genomic and trans criptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 2012;486:346-52.
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1    Shah, S.P.2    Chin, S.-F.3    Turashvili, G.4    Rueda, O.M.5    Dunning, M.J.6
  • 2
    • 84891625661 scopus 로고    scopus 로고
    • Molecularly targeted cancer therapy: Some lessons from the past decade
    • Huang M, Shen A, Ding J, Geng M. Molecularly targeted cancer therapy: some lessons from the past decade. Trends Pharmacol Sci 2014;35: 41-50.
    • (2014) Trends Pharmacol Sci , vol.35 , pp. 41-50
    • Huang, M.1    Shen, A.2    Ding, J.3    Geng, M.4
  • 3
    • 84879071011 scopus 로고    scopus 로고
    • Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
    • Shaw AT, Kim D-W, Nakagawa K, Seto T, Crino L, Ahn MJ, et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013;368:2385-94.
    • (2013) N Engl J Med , vol.368 , pp. 2385-2394
    • Shaw, A.T.1    Kim, D.-W.2    Nakagawa, K.3    Seto, T.4    Crino, L.5    Ahn, M.J.6
  • 4
    • 84863000299 scopus 로고    scopus 로고
    • The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
    • Diaz LA, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012;486:537-40.
    • (2012) Nature , vol.486 , pp. 537-540
    • Diaz, L.A.1    Williams, R.T.2    Wu, J.3    Kinde, I.4    Hecht, J.R.5    Berlin, J.6
  • 5
    • 84925229458 scopus 로고    scopus 로고
    • Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
    • Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, et al. Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature 2014;518:422-6.
    • (2014) Nature , vol.518 , pp. 422-426
    • Eirew, P.1    Steif, A.2    Khattra, J.3    Ha, G.4    Yap, D.5    Farahani, H.6
  • 6
    • 84942906239 scopus 로고    scopus 로고
    • DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts
    • Nguyen LV, Cox CL, Eirew P, Knapp DJHF, Pellacani D, Kannan N, et al. DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts. Nat Commun 2014;5:5871.
    • (2014) Nat Commun , vol.5 , pp. 5871
    • Nguyen, L.V.1    Cox, C.L.2    Eirew, P.3    Knapp, D.J.H.F.4    Pellacani, D.5    Kannan, N.6
  • 7
    • 84873084388 scopus 로고    scopus 로고
    • Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
    • Kreso A, O'Brien CA, van Galen P, Gan OI, Notta F, Brown AMK, et al. Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer. Science 2013;339:543-8.
    • (2013) Science , vol.339 , pp. 543-548
    • Kreso, A.1    O'Brien, C.A.2    Van Galen, P.3    Gan, O.I.4    Notta, F.5    Brown, A.M.K.6
  • 8
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med 2013;19:1423-37.
    • (2013) Nat Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 9
    • 84864285794 scopus 로고    scopus 로고
    • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    • Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du J, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 2012;487:500-4.
    • (2012) Nature , vol.487 , pp. 500-504
    • Straussman, R.1    Morikawa, T.2    Shee, K.3    Barzily-Rokni, M.4    Qian, Z.R.5    Du, J.6
  • 10
    • 84906895091 scopus 로고    scopus 로고
    • Patient-derived xenograft models: An emerging platform for translational cancer research
    • Hidalgo M, Amant F, Biankin AV, Budinska E, Byrne AT, Caldas C, et al. Patient-derived xenograft models: an emerging platform for translational cancer research. Cancer Discov 2014;4:998-1013.
    • (2014) Cancer Discov , vol.4 , pp. 998-1013
    • Hidalgo, M.1    Amant, F.2    Biankin, A.V.3    Budinska, E.4    Byrne, A.T.5    Caldas, C.6
  • 11
    • 84924281374 scopus 로고    scopus 로고
    • Patient-derived xenograft models of breast cancer and their predictive power
    • Whittle JR, Lewis MT, Lindeman GJ, Visvader JE. Patient-derived xenograft models of breast cancer and their predictive power. Breast Cancer Res 2015;17. doi:10.1186/s13058-015-0523-1.
    • (2015) Breast Cancer Res , pp. 17
    • Whittle, J.R.1    Lewis, M.T.2    Lindeman, G.J.3    Visvader, J.E.4
  • 12
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 2011;146:633-44.
    • (2011) Cell , vol.146 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3    Shapira, S.D.4    Tao, K.5    Kuperwasser, C.6
  • 13
    • 84897482887 scopus 로고    scopus 로고
    • Tumour cell heterogeneity maintained by cooperating subclones in wnt-driven mammary cancers
    • Cleary AS, Leonard TL, Gestl SA, Gunther EJ. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature 2014;508:113-7.
    • (2014) Nature , vol.508 , pp. 113-117
    • Cleary, A.S.1    Leonard, T.L.2    Gestl, S.A.3    Gunther, E.J.4
  • 14
    • 84874354257 scopus 로고    scopus 로고
    • The implications of clonal genome evolution for cancer medicine
    • Aparicio S, Caldas C. The implications of clonal genome evolution for cancer medicine. N Engl J Med 2013;368:842-51.
    • (2013) N Engl J Med , vol.368 , pp. 842-851
    • Aparicio, S.1    Caldas, C.2
  • 15
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012;486:395-9.
    • (2012) Nature , vol.486 , pp. 395-399
    • Shah, S.P.1    Roth, A.2    Goya, R.3    Oloumi, A.4    Ha, G.5    Zhao, Y.6
  • 16
    • 84885092663 scopus 로고    scopus 로고
    • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
    • Bashashati A, Ha G, Tone A, Ding J, Prentice LM, Roth A, et al. Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. J Pathol 2013;231: 21-34.
    • (2013) J Pathol , vol.231 , pp. 21-34
    • Bashashati, A.1    Ha, G.2    Tone, A.3    Ding, J.4    Prentice, L.M.5    Roth, A.6
  • 19
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010;464:999-1005.
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1    Ellis, M.J.2    Li, S.3    Larson, D.E.4    Chen, K.5    Wallis, J.W.6
  • 20
    • 84877579861 scopus 로고    scopus 로고
    • Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
    • Murtaza M, Dawson S-J, Tsui DWY, Gale D, Forshew T, Piskorz AM, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013;497:108-12.
    • (2013) Nature , vol.497 , pp. 108-112
    • Murtaza, M.1    Dawson, S.-J.2    Tsui, D.W.Y.3    Gale, D.4    Forshew, T.5    Piskorz, A.M.6
  • 21
    • 84860214990 scopus 로고    scopus 로고
    • Intra-tumour heterogeneity: A looking glass for cancer?
    • Marusyk A, Almendro V, Polyak K. Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 2012;12:323-34.
    • (2012) Nat Rev Cancer , vol.12 , pp. 323-334
    • Marusyk, A.1    Almendro, V.2    Polyak, K.3
  • 23
    • 84897549702 scopus 로고    scopus 로고
    • Understanding tissue context influences on intra-tumour heterogeneity
    • Michor F, Weaver VM. Understanding tissue context influences on intra-tumour heterogeneity. Nat Cell Biol 2014;16:301-2.
    • (2014) Nat Cell Biol , vol.16 , pp. 301-302
    • Michor, F.1    Weaver, V.M.2
  • 24
    • 84897543202 scopus 로고    scopus 로고
    • A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies
    • Wang C-C, Bajikar SS, Jamal L, Atkins KA, Janes KA. A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nat Cell Biol 2014;16:345-56.
    • (2014) Nat Cell Biol , vol.16 , pp. 345-356
    • Wang, C.-C.1    Bajikar, S.S.2    Jamal, L.3    Atkins, K.A.4    Janes, K.A.5
  • 25
    • 84923333334 scopus 로고    scopus 로고
    • Nanotechnology in the regeneration of complex tissues
    • Cassidy JW. Nanotechnology in the regeneration of complex tissues. Bone Tissue Regen Insights 2014;5:25-35.
    • (2014) Bone Tissue Regen Insights , vol.5 , pp. 25-35
    • Cassidy, J.W.1
  • 26
    • 84901020848 scopus 로고    scopus 로고
    • Cancer-as sociated fibroblasts as another polarized cell type of the tumor microenvironment
    • Augsten M. Cancer-as sociated fibroblasts as another polarized cell type of the tumor microenvironment. Front Oncol 2014;4:62.
    • (2014) Front Oncol , vol.4 , pp. 62
    • Augsten, M.1
  • 28
    • 84890262455 scopus 로고    scopus 로고
    • The role of mesenchymal stem cells in cancer development
    • Yagi H, Kitagawa Y. The role of mesenchymal stem cells in cancer development. Front Genet 2013;4:261.
    • (2013) Front Genet , vol.4 , pp. 261
    • Yagi, H.1    Kitagawa, Y.2
  • 29
    • 84920921528 scopus 로고    scopus 로고
    • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
    • Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014;515:577-81.
    • (2014) Nature , vol.515 , pp. 577-581
    • Gubin, M.M.1    Zhang, X.2    Schuster, H.3    Caron, E.4    Ward, J.P.5    Noguchi, T.6
  • 30
    • 44849101184 scopus 로고    scopus 로고
    • The humoral immune system has a key prognostic impact in node-negative breast cancer
    • Schmidt M, Bohm D, Von Torne C, Steiner E, Puhl A, Pilch H, et al. The humoral immune system has a key prognostic impact in node-negative breast cancer. Cancer Res 2008;68:5405-13.
    • (2008) Cancer Res , vol.68 , pp. 5405-5413
    • Schmidt, M.1    Bohm, D.2    Von Torne, C.3    Steiner, E.4    Puhl, A.5    Pilch, H.6
  • 31
    • 33846630040 scopus 로고    scopus 로고
    • Humanized mice in translational biomedical research
    • Shultz LD, Ishikawa F, Greiner DL. Humanized mice in translational biomedical research. Nat Rev Immunol 2007;7:118-30.
    • (2007) Nat Rev Immunol , vol.7 , pp. 118-130
    • Shultz, L.D.1    Ishikawa, F.2    Greiner, D.L.3
  • 33
    • 39149112228 scopus 로고    scopus 로고
    • A new hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene
    • King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, et al. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol 2008;126:303-14.
    • (2008) Clin Immunol , vol.126 , pp. 303-314
    • King, M.1    Pearson, T.2    Shultz, L.D.3    Leif, J.4    Bottino, R.5    Trucco, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.