Fully Automated One-Step Production of Functional 3D Tumor Spheroids for High-Content Screening

Journal of Laboratory Automation

Volumn 21, Issue 2, 2016, Pages 268-280

  Monjaret, François ^a   Fernandes, Mathieu ^a   Duchemin Pelletier, Eve ^a   Argento, Amelie ^a   Degot, Sébastien ^a   Young, Joanne ^a  

^a CYTOO SA   (France)

Author keywords

3D spheroids; assay development; high content screening; micropatterns

Indexed keywords

ASSAYS; CELL CULTURE; CELL DEATH; DRUG PRODUCTS; IMAGE PROCESSING; PLATES (STRUCTURAL COMPONENTS);

3D SPHEROIDS; ASSAY DEVELOPMENT; DRUG DISCOVERY APPLICATIONS; HIGH-CONTENT SCREENING; HIGH-THROUGHPUT SCREENING; MICROPATTERNS; STATISTICAL CONFIDENCE; THREE DIMENSIONAL (3D) STRUCTURES;

DIAGNOSIS;

COLLAGEN TYPE 1; FIBRONECTIN; FLUOROURACIL; IRINOTECAN; LAMININ; PROPIDIUM IODIDE; STAUROSPORINE;

ARTICLE; CELL DEATH; CELL HETEROGENEITY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; EC50; GROWTH RATE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC50; IMAGE ANALYSIS; MULTIPHOTON MICROSCOPY; SIGNAL NOISE RATIO; TUMOR SEEDING; TUMOR SPHEROID; BIOASSAY; CELL CULTURE TECHNIQUE; CELL SURVIVAL; DRUG DEVELOPMENT; FLUORESCENCE IMAGING; HT-29 CELL LINE; MULTICELLULAR SPHEROID; PROCEDURES; REPRODUCIBILITY;

BIOLOGICAL ASSAY; CELL CULTURE TECHNIQUES; CELL SURVIVAL; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HT29 CELLS; HUMANS; OPTICAL IMAGING; REPRODUCIBILITY OF RESULTS; SPHEROIDS, CELLULAR;

EID: 84962563869     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068215607058     Document Type: Article

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