Tissue-engineered 3D tumor angiogenesis models: Potential technologies for anti-cancer drug discovery

Advanced Drug Delivery Reviews

Volumn 79, Issue , 2014, Pages 30-39

  Chwalek, Karolina ^a,b,c   Bray, Laura J ^a,b   Werner, Carsten ^a,b  

^a LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^c TUFTS UNIVERSITY   (United States)

Author keywords

Biomaterials; Cancer; Endothelial cells; Matrix; Microfluidics; Scaffold; Vascularization

Indexed keywords

BIOMATERIALS; CELL CULTURE; CELL PROLIFERATION; DISEASES; ENDOTHELIAL CELLS; MATRIX ALGEBRA; MICROFLUIDICS; SCAFFOLDS; TUMORS;

ANTI-CANCER THERAPIES; CANCER; CURRENT LIMITATION; FUTURE CHALLENGES; INNOVATIVE SOLUTIONS; POTENTIAL TECHNOLOGIES; TUMOR ANGIOGENESIS; VASCULARIZATION;

SCAFFOLDS (BIOLOGY);

ANTINEOPLASTIC AGENT; FIBROBLAST GROWTH FACTOR 2; VASCULOTROPIN;

ANGIOGENESIS; BIOMEDICINE; BREAST CANCER; CANCER GROWTH; CANCER RESEARCH; CARCINOGENESIS; CELL POPULATION; CONTROLLED STUDY; DRUG DEVELOPMENT; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REVIEW; SOLID TUMOR; SPHEROID CELL; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; TUMOR MODEL; ANIMAL; BIOLOGICAL MODEL; DRUG DESIGN; MOLECULARLY TARGETED THERAPY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; PROCEDURES; VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DESIGN; DRUG DISCOVERY; HUMANS; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; TISSUE ENGINEERING;

EID: 84919679464     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.05.006     Document Type: Review

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