3D in vitro bioengineered tumors based on collagen I hydrogels

Biomaterials

Volumn 32, Issue 31, 2011, Pages 7905-7912

  Szot, Christopher S ^a   Buchanan, Cara F ^a   Freeman, Joseph W ^a   Rylander, Marissa N ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Collagen I; Hydrogel; Hypoxia; Three dimensional; Tumor microenvironment

Indexed keywords

AVAILABLE NUTRIENTS; CELL MATRIX INTERACTIONS; CELLULAR PROLIFERATIONS; COLLAGEN I; GENE EXPRESSION ANALYSIS; HUMAN BREAST CANCER CELLS; HYPOXIA; HYPOXIA-INDUCIBLE FACTORS; IN-VITRO; IN-VIVO; MATRIX; NUTRIENT DIFFUSION; SOLID TUMORS; THREE-DIMENSIONAL (3D); TISSUE CULTURE POLYSTYRENES; TUMOR MICROENVIRONMENT; TUMOR MODELS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR;

BIOCOMPATIBILITY; CELL PROLIFERATION; CELLS; COLLAGEN; GENE EXPRESSION; MONOLAYERS; NUTRIENTS; PHYSIOLOGICAL MODELS; POLYSTYRENES; SOFTWARE ARCHITECTURE; THREE DIMENSIONAL; TISSUE CULTURE; TISSUE ENGINEERING; TUMORS;

HYDROGELS;

COLLAGEN TYPE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; POLYSTYRENE; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; BIOCOMPATIBILITY; BIOENGINEERING; BREAST CANCER; CANCER CELL CULTURE; CELL DEATH; CELL HYPOXIA; CELL INTERACTION; CELL PROLIFERATION; CELL STRUCTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYDROGEL; IMMUNOFLUORESCENCE TEST; NUTRIENT; PHENOTYPE; PRIORITY JOURNAL; SOLID TUMOR; THREE DIMENSIONAL IN VITRO BIOENGINEERED TUMOR; TISSUE CULTURE; TUMOR GROWTH; UPREGULATION; ANIMAL; CELL SHAPE; CULTURE TECHNIQUE; DRUG EFFECT; EXPERIMENTAL NEOPLASM; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METHODOLOGY; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; VASCULARIZATION;

ANIMALS; BIOENGINEERING; CELL CULTURE TECHNIQUES; CELL DEATH; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; COLLAGEN TYPE I; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROGELS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80051804176     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.001     Document Type: Article

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