메뉴 건너뛰기




Volumn 25, Issue 10, 2015, Pages 1499-1507

The first five years of single-cell cancer genomics and beyond

Author keywords

[No Author keywords available]

Indexed keywords

MUTAGENIC AGENT;

EID: 84942917849     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.191098.115     Document Type: Review
Times cited : (286)

References (91)
  • 2
    • 49249091689 scopus 로고    scopus 로고
    • Is tumor growth sustained by rare cancer stem cells or dominant clones?
    • Adams JM, Strasser A. 2008. Is tumor growth sustained by rare cancer stem cells or dominant clones? Cancer Res 68: 4018-4021.
    • (2008) Cancer Res , vol.68 , pp. 4018-4021
    • Adams, J.M.1    Strasser, A.2
  • 3
    • 84882888788 scopus 로고    scopus 로고
    • Preclinical intravital microscopy of the tumour-stroma interface: Invasion, metastasis, and therapy response
    • Alexander S, Weigelin B, Winkler F, Friedl P. 2013. Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response. Curr Opin Cell Biol 25: 659-671.
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 659-671
    • Alexander, S.1    Weigelin, B.2    Winkler, F.3    Friedl, P.4
  • 10
    • 17044411374 scopus 로고    scopus 로고
    • Mutator phenotype in cancer: Timing and perspectives
    • Bielas JH, Loeb LA. 2005. Mutator phenotype in cancer: timing and perspectives. Environ Mol Mutagen 45: 206-213.
    • (2005) Environ Mol Mutagen , vol.45 , pp. 206-213
    • Bielas, J.H.1    Loeb, L.A.2
  • 13
    • 84884365015 scopus 로고    scopus 로고
    • The causes and consequences of genetic heterogeneity in cancer evolution
    • Burrell RA, McGranahan N, Bartek J, Swanton C. 2013. The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501: 338-345.
    • (2013) Nature , vol.501 , pp. 338-345
    • Burrell, R.A.1    McGranahan, N.2    Bartek, J.3    Swanton, C.4
  • 14
    • 35848964790 scopus 로고    scopus 로고
    • Breast tumor heterogeneity: Cancer stem cells or clonal evolution?
    • Campbell LL, Polyak K. 2007. Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle 6: 2332-2338.
    • (2007) Cell Cycle , vol.6 , pp. 2332-2338
    • Campbell, L.L.1    Polyak, K.2
  • 15
    • 33746074049 scopus 로고    scopus 로고
    • Stem cells: The real culprits in cancer?
    • Clarke MF, Becker MW. 2006. Stem cells: the real culprits in cancer? Sci Am 295: 52-59.
    • (2006) Sci Am , vol.295 , pp. 52-59
    • Clarke, M.F.1    Becker, M.W.2
  • 17
    • 84905502594 scopus 로고    scopus 로고
    • Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells
    • Dago AE, Stepansky A, Carlsson A, Luttgen M, Kendall J, Baslan T, Kolatkar A, Wigler M, Bethel K, Gross ME, et al. 2014. Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells. PLoS One 9: e101777.
    • (2014) PLoS One , vol.9 , pp. e101777
    • Dago, A.E.1    Stepansky, A.2    Carlsson, A.3    Luttgen, M.4    Kendall, J.5    Baslan, T.6    Kolatkar, A.7    Wigler, M.8    Bethel, K.9    Gross, M.E.10
  • 21
    • 84922311090 scopus 로고    scopus 로고
    • Expression profiling. Combinatorial labeling of single cells for gene expression cytometry
    • Fan HC, Fu GK, Fodor SP. 2015. Expression profiling. Combinatorial labeling of single cells for gene expression cytometry. Science 347: 1258367.
    • (2015) Science , vol.347 , pp. 1258367
    • Fan, H.C.1    Fu, G.K.2    Fodor, S.P.3
  • 22
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. 1990. A genetic model for colorectal tumorigenesis. Cell 61: 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 24
    • 84919372228 scopus 로고    scopus 로고
    • Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
    • Gawad C, Koh W, Quake SR. 2014. Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc Natl Acad Sci 111: 17947-17952.
    • (2014) Proc Natl Acad Sci , vol.111 , pp. 17947-17952
    • Gawad, C.1    Koh, W.2    Quake, S.R.3
  • 26
    • 0034870192 scopus 로고    scopus 로고
    • Quantifying biodiversity: Procedures and pitfalls in the measurement and comparison of species richness
    • Gotelli N, Colwell R. 2001. Quantifying biodiversity: procedures and pitfalls in the measurement and comparison of species richness. Ecol Lett 4: 379-391.
    • (2001) Ecol Lett , vol.4 , pp. 379-391
    • Gotelli, N.1    Colwell, R.2
  • 27
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M, Maley CC. 2012. Clonal evolution in cancer. Nature 481: 306-313.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 28
    • 84890526238 scopus 로고    scopus 로고
    • Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing
    • Guo H, Zhu P,WuX, Li X, WenL, Tang F. 2013. Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing. Genome Res 23: 2126-2135.
    • (2013) Genome Res , vol.23 , pp. 2126-2135
    • Guo, H.1    Zhu, P.2    Wu, X.3    Li, X.4    Wen, L.5    Tang, F.6
  • 29
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. 2011. Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 84866953427 scopus 로고    scopus 로고
    • CEL-Seq: Single-cell RNAseq by multiplexed linear amplification
    • Hashimshony T, Wagner F, Sher N, Yanai I. 2012. CEL-Seq: single-cell RNAseq by multiplexed linear amplification. Cell Rep 2: 666-673.
    • (2012) Cell Rep , vol.2 , pp. 666-673
    • Hashimshony, T.1    Wagner, F.2    Sher, N.3    Yanai, I.4
  • 33
    • 0036570224 scopus 로고    scopus 로고
    • Multivariate analysis of chromosomal imbalances in breast cancer delineates cytogenetic pathways and reveals complex relationships among imbalances
    • Höglund M, Gisselsson D, Hansen GB, Säll T, Mitelman F. 2002. Multivariate analysis of chromosomal imbalances in breast cancer delineates cytogenetic pathways and reveals complex relationships among imbalances. Cancer Res 62: 2675-2680.
    • (2002) Cancer Res , vol.62 , pp. 2675-2680
    • Höglund, M.1    Gisselsson, D.2    Hansen, G.B.3    Säll, T.4    Mitelman, F.5
  • 34
    • 84863229772 scopus 로고    scopus 로고
    • Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm
    • Hou Y, Song L, Zhu P, Zhang B, Tao Y, Xu X, Li F,WuK, Liang J, Shao D, et al. 2012. Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell 148: 873-885.
    • (2012) Cell , vol.148 , pp. 873-885
    • Hou, Y.1    Song, L.2    Zhu, P.3    Zhang, B.4    Tao, Y.5    Xu, X.6    Li, F.7    Wu, K.8    Liang, J.9    Shao, D.10
  • 38
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. 2009. The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 42
    • 84887255230 scopus 로고    scopus 로고
    • Single-cell sequencing analysis characterizes common and cell-lineagespecific mutations in a muscle-invasive bladder cancer
    • Li Y, Xu X, Song L, Hou Y, Li Z, Tsang S, Li F, Im KM,WuK,WuH, et al. 2012. Single-cell sequencing analysis characterizes common and cell-lineagespecific mutations in a muscle-invasive bladder cancer. Gigascience 1: 12.
    • (2012) Gigascience , vol.1 , pp. 12
    • Li, Y.1    Xu, X.2    Song, L.3    Hou, Y.4    Li, Z.5    Tsang, S.6    Li, F.7    Im, K.M.8    Wu, K.9    Wu, H.10
  • 43
    • 3242791054 scopus 로고    scopus 로고
    • Strategies for microarray analysis of limiting amounts of RNA
    • Livesey FJ. 2003. Strategies for microarray analysis of limiting amounts of RNA. Brief Funct Genomic Proteomic 2: 31-36.
    • (2003) Brief Funct Genomic Proteomic , vol.2 , pp. 31-36
    • Livesey, F.J.1
  • 44
    • 79957501125 scopus 로고    scopus 로고
    • Human cancers express mutator phenotypes: Origin, consequences and targeting
    • Loeb LA. 2011. Human cancers express mutator phenotypes: origin, consequences and targeting. Nat Rev Cancer 11: 450-457.
    • (2011) Nat Rev Cancer , vol.11 , pp. 450-457
    • Loeb, L.A.1
  • 45
    • 0016176530 scopus 로고
    • Errors in DNA replication as a basis of malignant changes
    • Loeb LA, Springgate CF, Battula N. 1974. Errors in DNA replication as a basis of malignant changes. Cancer Res 34: 2311-2321.
    • (1974) Cancer Res , vol.34 , pp. 2311-2321
    • Loeb, L.A.1    Springgate, C.F.2    Battula, N.3
  • 51
    • 84878251993 scopus 로고    scopus 로고
    • Adapting clinical paradigms to the challenges of cancer clonal evolution
    • Murugaesu N, Chew SK, Swanton C. 2013. Adapting clinical paradigms to the challenges of cancer clonal evolution. Am J Pathol 182: 1962-1971.
    • (2013) Am J Pathol , vol.182 , pp. 1962-1971
    • Murugaesu, N.1    Chew, S.K.2    Swanton, C.3
  • 53
    • 85027920141 scopus 로고    scopus 로고
    • Cancer genomics: One cell at a time
    • Navin NE. 2014a. Cancer genomics: one cell at a time. Genome Biol 15: 452.
    • (2014) Genome Biol , vol.15 , pp. 452
    • Navin, N.E.1
  • 54
    • 84893860363 scopus 로고    scopus 로고
    • Tumor evolution in response to chemotherapy: Phenotype versus genotype
    • Navin NE. 2014b. Tumor evolution in response to chemotherapy: phenotype versus genotype. Cell Rep 6: 417-419.
    • (2014) Cell Rep , vol.6 , pp. 417-419
    • Navin, N.E.1
  • 55
    • 77953870937 scopus 로고    scopus 로고
    • Tracing the tumor lineage
    • Navin NE, Hicks J. 2010. Tracing the tumor lineage. Mol Oncol 4: 267-283.
    • (2010) Mol Oncol , vol.4 , pp. 267-283
    • Navin, N.E.1    Hicks, J.2
  • 58
    • 84891354380 scopus 로고    scopus 로고
    • Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
    • Ni X, Zhuo M, Su Z, Duan J, Gao Y, Wang Z, Zong C, Bai H, Chapman AR, Zhao J, et al. 2013. Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients. Proc Natl Acad Sci 110: 21083-21088.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. 21083-21088
    • Ni, X.1    Zhuo, M.2    Su, Z.3    Duan, J.4    Gao, Y.5    Wang, Z.6    Zong, C.7    Bai, H.8    Chapman, A.R.9    Zhao, J.10
  • 60
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. 2012. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12: 252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 63
    • 36248991811 scopus 로고    scopus 로고
    • Breast cancer stem cells: A case of mistaken identity?
    • Polyak K. 2007. Breast cancer stem cells: a case of mistaken identity? Stem Cell Rev 3: 107-109.
    • (2007) Stem Cell Rev , vol.3 , pp. 107-109
    • Polyak, K.1
  • 64
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. 2009. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9: 265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 70
    • 84891404742 scopus 로고    scopus 로고
    • Organoid cultures for the analysis of cancer phenotypes
    • Sachs N, Clevers H. 2014. Organoid cultures for the analysis of cancer phenotypes. Curr Opin Genet Dev 24: 68-73.
    • (2014) Curr Opin Genet Dev , vol.24 , pp. 68-73
    • Sachs, N.1    Clevers, H.2
  • 72
    • 42549099061 scopus 로고    scopus 로고
    • The cancer stem cell hypothesis: In search of definitions, markers, and relevance
    • Shipitsin M, Polyak K. 2008. The cancer stem cell hypothesis: in search of definitions, markers, and relevance. Lab Invest 88: 459-463.
    • (2008) Lab Invest , vol.88 , pp. 459-463
    • Shipitsin, M.1    Polyak, K.2
  • 73
    • 84923647450 scopus 로고    scopus 로고
    • Computational and analytical challenges in single-cell transcriptomics
    • Stegle O, Teichmann SA, Marioni JC. 2015. Computational and analytical challenges in single-cell transcriptomics. Nat Rev Genet 16: 133-145.
    • (2015) Nat Rev Genet , vol.16 , pp. 133-145
    • Stegle, O.1    Teichmann, S.A.2    Marioni, J.C.3
  • 75
    • 34648821257 scopus 로고    scopus 로고
    • Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
    • Stingl J, Caldas C. 2007. Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat Rev Cancer 7: 791-799.
    • (2007) Nat Rev Cancer , vol.7 , pp. 791-799
    • Stingl, J.1    Caldas, C.2
  • 76
    • 84939202318 scopus 로고    scopus 로고
    • Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment
    • Suzuki A, Matsushima K, Makinoshima H, Sugano S, Kohno T, Tsuchihara K, Suzuki Y. 2015. Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment. Genome Biol 16: 66.
    • (2015) Genome Biol , vol.16 , pp. 66
    • Suzuki, A.1    Matsushima, K.2    Makinoshima, H.3    Sugano, S.4    Kohno, T.5    Tsuchihara, K.6    Suzuki, Y.7
  • 79
    • 65349131893 scopus 로고    scopus 로고
    • Cancer stem cells: A guide for skeptics
    • Tomasson MH. 2009. Cancer stem cells: a guide for skeptics. J Cell Biochem 106: 745-749.
    • (2009) J Cell Biochem , vol.106 , pp. 745-749
    • Tomasson, M.H.1
  • 80
    • 84896286643 scopus 로고    scopus 로고
    • Single cell analysis of cancer genomes
    • Van Loo P, Voet T. 2014. Single cell analysis of cancer genomes. Curr Opin Genet Dev 24: 82-91.
    • (2014) Curr Opin Genet Dev , vol.24 , pp. 82-91
    • Van Loo, P.1    Voet, T.2
  • 81
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, et al. 2010. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17: 98-110.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6    Miller, C.R.7    Ding, L.8    Golub, T.9    Mesirov, J.P.10
  • 82
    • 84929661801 scopus 로고    scopus 로고
    • Advances and applications of single-cell sequencing technologies
    • Wang Y, Navin NE. 2015. Advances and applications of single-cell sequencing technologies. Mol Cell 58: 598-609.
    • (2015) Mol Cell , vol.58 , pp. 598-609
    • Wang, Y.1    Navin, N.E.2
  • 84
    • 70749147623 scopus 로고    scopus 로고
    • The theory of discovering rare variants via DNA sequencing
    • Wendl MC, Wilson RK. 2009. The theory of discovering rare variants via DNA sequencing. BMC Genomics 10: 485.
    • (2009) BMC Genomics , vol.10 , pp. 485
    • Wendl, M.C.1    Wilson, R.K.2
  • 86
    • 84863230091 scopus 로고    scopus 로고
    • Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor
    • Xu X, Hou Y, Yin X, Bao L, Tang A, Song L, Li F, Tsang S, Wu K, Wu H, et al. 2012. Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell 148: 886-895.
    • (2012) Cell , vol.148 , pp. 886-895
    • Xu, X.1    Hou, Y.2    Yin, X.3    Bao, L.4    Tang, A.5    Song, L.6    Li, F.7    Tsang, S.8    Wu, K.9    Wu, H.10
  • 87
    • 84901835055 scopus 로고    scopus 로고
    • Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing
    • Yu C, Yu J, Yao X, WuWK, Lu Y, Tang S, Li X, Bao L, Li X, Hou Y, et al. 2014. Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing. Cell Res 24: 701-712.
    • (2014) Cell Res , vol.24 , pp. 701-712
    • Yu, C.1    Yu, J.2    Yao, X.3    Wuwk Lu, Y.4    Tang, S.5    Li, X.6    Bao, L.7    Li, X.8    Hou, Y.9
  • 91
    • 84871461434 scopus 로고    scopus 로고
    • Genome-wide detection of singlenucleotide and copy-number variations of a single human cell
    • Zong C, Lu S, Chapman AR, Xie XS. 2012. Genome-wide detection of singlenucleotide and copy-number variations of a single human cell. Science 338: 1622-1626.
    • (2012) Science , vol.338 , pp. 1622-1626
    • Zong, C.1    Lu, S.2    Chapman, A.R.3    Xie, X.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.