-
1
-
-
70350719355
-
Heme oxygenase: the key to renal function regulation
-
Abraham, N. G., Cao, J., Sacerdoti, D., Li, X., and Drummond, G. (2009). Heme oxygenase: the key to renal function regulation. Am. J. Physiol. Renal Physiol. 297, F1137-F1152. doi: 10.1152/ajprenal.90449.2008
-
(2009)
Am. J. Physiol. Renal Physiol
, vol.297
, pp. F1137-F1152
-
-
Abraham, N.G.1
Cao, J.2
Sacerdoti, D.3
Li, X.4
Drummond, G.5
-
2
-
-
0020983340
-
"Heme metabolism in hepatic and erythroid cells,"
-
ed E Brown (New York: Grune and Stratton)
-
Abraham, N. G., Friedland, M. L., and Lever, R. (1983). "Heme metabolism in hepatic and erythroid cells," in Progress in Hematology, ed E. Brown (New York: Grune and Stratton), 75-130
-
(1983)
in Progress in Hematology
, pp. 75-130
-
-
Abraham, N.G.1
Friedland, M.L.2
Lever, R.3
-
3
-
-
19544370917
-
Heme oxygenase and the cardiovascular-renal system
-
Abraham, N. G., and Kappas, A. (2005). Heme oxygenase and the cardiovascular-renal system. Free Radic. Biol. Med. 39, 1-25. doi: 10.1016/j.freeradbiomed.2005.03.010
-
(2005)
Free Radic. Biol. Med
, vol.39
, pp. 1-25
-
-
Abraham, N.G.1
Kappas, A.2
-
4
-
-
41149177025
-
Pharmacological and clinical aspects of heme oxygenase
-
Abraham, N. G., and Kappas, A. (2008). Pharmacological and clinical aspects of heme oxygenase. Pharmacol. Rev. 60, 79-127. doi: 10.1124/pr.107.07104
-
(2008)
Pharmacol. Rev
, vol.60
, pp. 79-127
-
-
Abraham, N.G.1
Kappas, A.2
-
5
-
-
0023778922
-
The physiological significance of heme oxygenase
-
Abraham, N. G., Lin, J. H., Schwartzman, M. L., Levere, R. D., and Shibahara, S. (1988). The physiological significance of heme oxygenase. Int. J. Biochem. 20, 543-558. doi: 10.1016/0020-711X(88)90093-6
-
(1988)
Int. J. Biochem
, vol.20
, pp. 543-558
-
-
Abraham, N.G.1
Lin, J.H.2
Schwartzman, M.L.3
Levere, R.D.4
Shibahara, S.5
-
6
-
-
0019073710
-
Kinetics and mechanism of the interaction between human serum albumin and monomeric haemin
-
Adams, P. A., and Berman, M. C. (1980). Kinetics and mechanism of the interaction between human serum albumin and monomeric haemin. Biochem. J. 191, 95-102. doi: 10.1042/bj1910095
-
(1980)
Biochem. J
, vol.191
, pp. 95-102
-
-
Adams, P.A.1
Berman, M.C.2
-
7
-
-
0021322523
-
Hemin-mediated oxidative degradation of proteins
-
Aft, R. L., and Mueller, G. C. (1984). Hemin-mediated oxidative degradation of proteins. J. Biol. Chem. 259, 301-305
-
(1984)
J. Biol. Chem
, vol.259
, pp. 301-305
-
-
Aft, R.L.1
Mueller, G.C.2
-
8
-
-
0021100151
-
Hemin-mediated DNA strand scission
-
Aft, R. L., and Mueller, G. C. (1983). Hemin-mediated DNA strand scission. J. Biol. Chem. 258, 12069-12072
-
(1983)
J. Biol. Chem
, vol.258
, pp. 12069-12072
-
-
Aft, R.L.1
Mueller, G.C.2
-
9
-
-
84954566423
-
Heme attenuation ameliorates irritant gas inhalation-induced acute lung injury
-
Aggarwal, S., Lam, A., Bolisetty, S., Carlisle, M. A., Traylor, A., Agarwal, A., et al. (2016). Heme attenuation ameliorates irritant gas inhalation-induced acute lung injury. Antioxid. Redox Signal. 24, 99-112. doi: 10.1089/ars.2015.6347
-
(2016)
Antioxid. Redox Signal
, vol.24
, pp. 99-112
-
-
Aggarwal, S.1
Lam, A.2
Bolisetty, S.3
Carlisle, M.A.4
Traylor, A.5
Agarwal, A.6
-
10
-
-
0037085766
-
Processing of the lipocalin a1-microglobulin by hemoglobin induces heme-binding and heme-degradation properties
-
Allhorn, M., Berggard, T., Nordberg, J., Olsson, M. L., and Akerstrom, B. (2002). Processing of the lipocalin a1-microglobulin by hemoglobin induces heme-binding and heme-degradation properties. Blood 99, 1894-1901. doi: 10.1182/blood.V99.6.1894
-
(2002)
Blood
, vol.99
, pp. 1894-1901
-
-
Allhorn, M.1
Berggard, T.2
Nordberg, J.3
Olsson, M.L.4
Akerstrom, B.5
-
11
-
-
84943183889
-
Heme-induced contractile dysfunction in human cardiomyocytes caused by oxidant damage to thick filament proteins
-
Alvarado, G., Jeney, V., Toth, A., Csosz, E., Kallo, G., Huynh, A. T., et al. (2015). Heme-induced contractile dysfunction in human cardiomyocytes caused by oxidant damage to thick filament proteins. Free Radic. Biol. Med. 89, 248-262. doi: 10.1016/j.freeradbiomed.2015.07.158
-
(2015)
Free Radic. Biol. Med
, vol.89
, pp. 248-262
-
-
Alvarado, G.1
Jeney, V.2
Toth, A.3
Csosz, E.4
Kallo, G.5
Huynh, A.T.6
-
12
-
-
77955507567
-
Heme impairs prostaglandin E2 and TGF-β production by human mononuclear cells via Cu/Zn superoxide dismutase: insight into the pathogenesis of severe malaria
-
Andrade, B. B., Araujo-Santos, T., Luz, N. F., Khouri, R., Bozza, M. T., Camargo, L. M., et al. (2010). Heme impairs prostaglandin E2 and TGF-β production by human mononuclear cells via Cu/Zn superoxide dismutase: insight into the pathogenesis of severe malaria. J. Immunol. 185, 1196-1204. doi: 10.4049/jimmunol.0904179
-
(2010)
J. Immunol
, vol.185
, pp. 1196-1204
-
-
Andrade, B.B.1
Araujo-Santos, T.2
Luz, N.F.3
Khouri, R.4
Bozza, M.T.5
Camargo, L.M.6
-
13
-
-
84883076264
-
Severe sepsis and septic shock
-
Angus, D. C., and van der Poll, T. (2013). Severe sepsis and septic shock. N. Engl. J. Med. 369, 840-851. doi: 10.1056/NEJMra1208623
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 840-851
-
-
Angus, D.C.1
van der Poll, T.2
-
14
-
-
84859712543
-
Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy
-
Baek, J. H., D'Agnillo, F., Vallelian, F., Pereira, C. P., Williams, M. C., Jia, Y., et al. (2012). Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy. J. Clin. Invest. 122, 1444-1458. doi: 10.1172/JCI59770
-
(2012)
J. Clin. Invest
, vol.122
, pp. 1444-1458
-
-
Baek, J.H.1
D'Agnillo, F.2
Vallelian, F.3
Pereira, C.P.4
Williams, M.C.5
Jia, Y.6
-
15
-
-
26944501268
-
Protease activity of plasma hemopexin
-
Bakker, W. W., Borghuis, T., Harmsen, M. C. A., Van den Berg, A., Kema, I. P., Niezen, K. E., et al. (2005). Protease activity of plasma hemopexin. Kidney Int. 68, 603-610. doi: 10.1111/j.1523-1755.2005.00438.x
-
(2005)
Kidney Int
, vol.68
, pp. 603-610
-
-
Bakker, W.W.1
Borghuis, T.2
Harmsen, M.C.A.3
Van den Berg, A.4
Kema, I.P.5
Niezen, K.E.6
-
16
-
-
0026657174
-
Ferritin: a cytoprotective antioxidant strategem of endothelium
-
Balla, G., Jacob, H. S., Balla, J., Rosenberg, M., Nath, K., Apple, F., et al. (1992). Ferritin: a cytoprotective antioxidant strategem of endothelium. J. Biol. Chem. 267, 18148-18153
-
(1992)
J. Biol. Chem
, vol.267
, pp. 18148-18153
-
-
Balla, G.1
Jacob, H.S.2
Balla, J.3
Rosenberg, M.4
Nath, K.5
Apple, F.6
-
17
-
-
0025819677
-
Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species
-
Balla, G., Vercellotti, G. M., Muller-Eberhard, U., Eaton, J., and Jacob, H. S. (1991). Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species. Lab. Invest. 64, 648-655
-
(1991)
Lab. Invest
, vol.64
, pp. 648-655
-
-
Balla, G.1
Vercellotti, G.M.2
Muller-Eberhard, U.3
Eaton, J.4
Jacob, H.S.5
-
18
-
-
0027358877
-
Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage
-
Balla, J., Jacob, H. S., Balla, G., Nath, K., Eaton, J. W., and Vercellotti, G. (1993). Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc. Natl. Acad. Sci. U.S.A. 90, 9285-9289. doi: 10.1073/pnas.90.20.9285
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 9285-9289
-
-
Balla, J.1
Jacob, H.S.2
Balla, G.3
Nath, K.4
Eaton, J.W.5
Vercellotti, G.6
-
19
-
-
0037569694
-
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
-
Balogun, E., Hoque, M., Gong, P., Killeen, E., Green, C. J., Foresti, R., et al. (2003). Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem. J. 371, 887-895. doi: 10.1042/bj20021619
-
(2003)
Biochem. J
, vol.371
, pp. 887-895
-
-
Balogun, E.1
Hoque, M.2
Gong, P.3
Killeen, E.4
Green, C.J.5
Foresti, R.6
-
20
-
-
0028095919
-
The acute phase response
-
Baumann, H., and Gauldie, J. (1994). The acute phase response. Immunol. Today 15, 74-80. doi: 10.1016/0167-5699(94)90137-6
-
(1994)
Immunol. Today
, vol.15
, pp. 74-80
-
-
Baumann, H.1
Gauldie, J.2
-
21
-
-
84868583137
-
Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease
-
Bean, C. J., Boulet, S. L., Ellingsen, D., Pyle, M. E., Barron-Casella, E. A., Casella, J. F., et al. (2012). Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease. Blood 120, 3822-3828. doi: 10.1182/blood-2011-06-361642
-
(2012)
Blood
, vol.120
, pp. 3822-3828
-
-
Bean, C.J.1
Boulet, S.L.2
Ellingsen, D.3
Pyle, M.E.4
Barron-Casella, E.A.5
Casella, J.F.6
-
22
-
-
0037588990
-
Transgenic sickle mice have vascular inflammation
-
Belcher, J. D., Bryant, C. J., Nguyen, J., Bowlin, P. R., Kielbik, M. C., Bischof, J. C., et al. (2003). Transgenic sickle mice have vascular inflammation. Blood 101, 3953-3959. doi: 10.1182/blood-2002-10-3313
-
(2003)
Blood
, vol.101
, pp. 3953-3959
-
-
Belcher, J.D.1
Bryant, C.J.2
Nguyen, J.3
Bowlin, P.R.4
Kielbik, M.C.5
Bischof, J.C.6
-
23
-
-
84894567032
-
Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease
-
Belcher, J. D., Chen, C., Nguyen, J., Milbauer, L., Abdulla, F., Alayash, A. I., et al. (2014). Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Blood 123, 377-390. doi: 10.1182/blood-2013-04-495887
-
(2014)
Blood
, vol.123
, pp. 377-390
-
-
Belcher, J.D.1
Chen, C.2
Nguyen, J.3
Milbauer, L.4
Abdulla, F.5
Alayash, A.I.6
-
24
-
-
85018976715
-
Control of oxidative stress and inflammation in sickle cell disease with the Nrf2 activator dimethyl fumarate
-
[Epub ahead of print]
-
Belcher, J. D., Chen, C., Nguyen, J., Zhang, P., Abdulla, F., Nguyen, P., et al. (2016). Control of oxidative stress and inflammation in sickle cell disease with the Nrf2 activator dimethyl fumarate. Antioxid. Redox Signal. doi: 10.1089/ars.2015.6571. [Epub ahead of print]
-
(2016)
Antioxid. Redox Signal
-
-
Belcher, J.D.1
Chen, C.2
Nguyen, J.3
Zhang, P.4
Abdulla, F.5
Nguyen, P.6
-
25
-
-
33644649611
-
Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice
-
Belcher, J. D., Mahaseth, H., Welch, T. E., Otterbein, L. E., Hebbel, R. P., and Vercellotti, G. M. (2006). Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. J. Clin. Invest. 116, 808-816. doi: 10.1172/JCI26857
-
(2006)
J. Clin. Invest
, vol.116
, pp. 808-816
-
-
Belcher, J.D.1
Mahaseth, H.2
Welch, T.E.3
Otterbein, L.E.4
Hebbel, R.P.5
Vercellotti, G.M.6
-
26
-
-
77954541322
-
Heme oxygenase-1 gene delivery by sleeping beauty inhibits vascular stasis in a murine model of sickle cell disease
-
Belcher, J. D., Vineyard, J. V., Bruzzone, C. M., Chen, C., Beckman, J. D., Nguyen, J., et al. (2010). Heme oxygenase-1 gene delivery by sleeping beauty inhibits vascular stasis in a murine model of sickle cell disease. J. Mol. Med. (Berl.) 88, 665-675. doi: 10.1007/s00109-010-0613-6
-
(2010)
J. Mol. Med. (Berl.)
, vol.88
, pp. 665-675
-
-
Belcher, J.D.1
Vineyard, J.V.2
Bruzzone, C.M.3
Chen, C.4
Beckman, J.D.5
Nguyen, J.6
-
27
-
-
0015489656
-
Hemoglobin and erythrocyte catabolism in rat liver: the separate roles of parenchymal and sinusoidal cells
-
Bissell, D. M., Hammaker, L., and Schmid, R. (1972). Hemoglobin and erythrocyte catabolism in rat liver: the separate roles of parenchymal and sinusoidal cells. Blood 40, 812-822
-
(1972)
Blood
, vol.40
, pp. 812-822
-
-
Bissell, D.M.1
Hammaker, L.2
Schmid, R.3
-
28
-
-
84934441179
-
Macrophage and epithelial cell H-ferritin expression regulates renal inflammation
-
Bolisetty, S., Zarjou, A., Hull, T. D., Traylor, A. M., Perianayagam, A., Joseph, R., et al. (2015). Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 88, 95-108. doi: 10.1038/ki.2015.102
-
(2015)
Kidney Int
, vol.88
, pp. 95-108
-
-
Bolisetty, S.1
Zarjou, A.2
Hull, T.D.3
Traylor, A.M.4
Perianayagam, A.5
Joseph, R.6
-
29
-
-
0025887774
-
Let's agree on terminology: definitions of sepsis
-
Bone, R. C. (1991). Let's agree on terminology: definitions of sepsis. Crit. Care Med. 19, 973-976. doi: 10.1097/00003246-199107000-00024
-
(1991)
Crit. Care Med
, vol.19
, pp. 973-976
-
-
Bone, R.C.1
-
30
-
-
0015153851
-
Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusions of hematin
-
Bonkowsky, H. L., Tschudy, D. P., Collins, A., Doherty, J., Bossenmaier, I., Cardinal, R., et al. (1971). Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusions of hematin. Proc. Natl. Acad. Sci. U.S.A. 68, 2725-2729. doi: 10.1073/pnas.68.11.2725
-
(1971)
Proc. Natl. Acad. Sci. U.S.A
, vol.68
, pp. 2725-2729
-
-
Bonkowsky, H.L.1
Tschudy, D.P.2
Collins, A.3
Doherty, J.4
Bossenmaier, I.5
Cardinal, R.6
-
31
-
-
0014408353
-
Exchange of heme among hemoglobins and between hemoglobin and albumin
-
Bunn, H. F., and Jandl, J. H. (1968). Exchange of heme among hemoglobins and between hemoglobin and albumin. J. Biol. Chem. 243, 465-475
-
(1968)
J. Biol. Chem
, vol.243
, pp. 465-475
-
-
Bunn, H.F.1
Jandl, J.H.2
-
32
-
-
40049109300
-
Nuclear hormone receptors for heme: REV-ERBa and REV-ERBβ are ligand-regulated components of the mammalian clock
-
Burris, T. P. (2008). Nuclear hormone receptors for heme: REV-ERBa and REV-ERBβ are ligand-regulated components of the mammalian clock. Mol. Endocrinol. 22, 1509-1520. doi: 10.1210/me.2007-0519
-
(2008)
Mol. Endocrinol
, vol.22
, pp. 1509-1520
-
-
Burris, T.P.1
-
33
-
-
84896343373
-
The multifunctional role and therapeutic potential of HO-1 in the vascular endothelium
-
Calay, D., and Mason, J. C. (2014). The multifunctional role and therapeutic potential of HO-1 in the vascular endothelium. Antioxid. Redox Signal. 20, 1789-1809. doi: 10.1089/ars.2013.5659
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 1789-1809
-
-
Calay, D.1
Mason, J.C.2
-
34
-
-
84931271446
-
Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease
-
Camus, S. M., De Moraes, J. A., Bonnin, P., Abbyad, P., Le Jeune, S., Lionnet, F., et al. (2015). Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease. Blood 125, 3805-3814. doi: 10.1182/blood-2014-07-589283
-
(2015)
Blood
, vol.125
, pp. 3805-3814
-
-
Camus, S.M.1
De Moraes, J.A.2
Bonnin, P.3
Abbyad, P.4
Le Jeune, S.5
Lionnet, F.6
-
35
-
-
84864281998
-
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet
-
Cao, J., Peterson, S. J., Sodhi, K., Vanella, L., Barbagallo, I., Rodella, L. F., et al. (2012). Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension 60, 467-475. doi: 10.1161/HYPERTENSIONAHA.112.193805
-
(2012)
Hypertension
, vol.60
, pp. 467-475
-
-
Cao, J.1
Peterson, S.J.2
Sodhi, K.3
Vanella, L.4
Barbagallo, I.5
Rodella, L.F.6
-
36
-
-
79952659297
-
Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension
-
Cao, J., Sodhi, K., Inoue, K., Quilley, J., Rezzani, R., Rodella, L., et al. (2011). Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension. Hum. Gene Ther. 22, 271-282. doi: 10.1089/hum.2010.059
-
(2011)
Hum. Gene Ther
, vol.22
, pp. 271-282
-
-
Cao, J.1
Sodhi, K.2
Inoue, K.3
Quilley, J.4
Rezzani, R.5
Rodella, L.6
-
37
-
-
78149239781
-
GAPDH regulates cellular heme insertion into inducible nitric oxide synthase
-
Chakravarti, R., Aulak, K. S., Fox, P. L., and Stuehr, D. J. (2010). GAPDH regulates cellular heme insertion into inducible nitric oxide synthase. Proc. Natl. Acad. Sci. U.S.A. 107, 18004-18009. doi: 10.1073/pnas.1008133107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 18004-18009
-
-
Chakravarti, R.1
Aulak, K.S.2
Fox, P.L.3
Stuehr, D.J.4
-
38
-
-
0014075737
-
The reactivity of haemoproteins and cytochromes
-
Chance, B. (1967). The reactivity of haemoproteins and cytochromes. Biochem. J. 103, 1-18. doi: 10.1042/bj1030001
-
(1967)
Biochem. J
, vol.103
, pp. 1-18
-
-
Chance, B.1
-
39
-
-
0036705418
-
Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection
-
Chauveau, C., Bouchet, D., Roussel, J. C., Mathieu, P., Braudeau, C., Renaudin, K., et al. (2002). Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection. Am. J. Transplant. 2, 581-592. doi: 10.1034/j.1600-6143.2002.20702.x
-
(2002)
Am. J. Transplant
, vol.2
, pp. 581-592
-
-
Chauveau, C.1
Bouchet, D.2
Roussel, J.C.3
Mathieu, P.4
Braudeau, C.5
Renaudin, K.6
-
40
-
-
84902585238
-
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
-
Chen, G., Zhang, D., Fuchs, T. A., Manwani, D., Wagner, D. D., and Frenette, P. S. (2014). Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood 123, 3818-3827. doi: 10.1182/blood-2013-10-529982
-
(2014)
Blood
, vol.123
, pp. 3818-3827
-
-
Chen, G.1
Zhang, D.2
Fuchs, T.A.3
Manwani, D.4
Wagner, D.D.5
Frenette, P.S.6
-
41
-
-
0013646663
-
Is 100KF an isoform of hemopexi?. Immunochemical characterization of the vasoactive plasma factor 100KF
-
Cheung, P. K., Stulp, B., Immenschuh, S., Borghuis, T., Baller, J. F., and Bakker, W. (1999). Is 100KF an isoform of hemopexin? Immunochemical characterization of the vasoactive plasma factor 100KF. J. Am. Soc. Nephrol. 10, 1700-1708
-
(1999)
J. Am. Soc. Nephrol
, vol.10
, pp. 1700-1708
-
-
Cheung, P.K.1
Stulp, B.2
Immenschuh, S.3
Borghuis, T.4
Baller, J.F.5
Bakker, W.6
-
42
-
-
84980319854
-
Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes
-
Chiabrando, D., Vinchi, F., Fiorito, V., Mercurio, S., and Tolosano, E. (2014). Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes. Front. Pharmacol. 5:61. doi: 10.3389/fphar.2014.00061
-
(2014)
Front. Pharmacol
, vol.5
, pp. 61
-
-
Chiabrando, D.1
Vinchi, F.2
Fiorito, V.3
Mercurio, S.4
Tolosano, E.5
-
43
-
-
84946195292
-
Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity
-
Deuel, J. W., Vallelian, F., Schaer, C. A., Puglia, M., Buehler, P. W., and Schaer, D. J. (2015). Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity. Free Radic. Biol. Med. 89, 931-943. doi: 10.1016/j.freeradbiomed.2015.09.016
-
(2015)
Free Radic. Biol. Med
, vol.89
, pp. 931-943
-
-
Deuel, J.W.1
Vallelian, F.2
Schaer, C.A.3
Puglia, M.4
Buehler, P.W.5
Schaer, D.J.6
-
44
-
-
33646036427
-
Hemin activation ameliorates HIV-1 infection via heme oxygenase-1 induction
-
Devadas, K., and Dhawan, S. (2006). Hemin activation ameliorates HIV-1 infection via heme oxygenase-1 induction. J. Immunol. 176, 4252-4257. doi: 10.4049/jimmunol.176.7.4252
-
(2006)
J. Immunol
, vol.176
, pp. 4252-4257
-
-
Devadas, K.1
Dhawan, S.2
-
45
-
-
78649440265
-
Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects
-
Doberer, D., Haschemi, A., Andreas, M., Zapf, T. C., Clive, B., Jeitler, M., et al. (2010). Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects. Br. J. Pharmacol. 161, 1751-1762. doi: 10.1111/j.1476-5381.2010.00990.x
-
(2010)
Br. J. Pharmacol
, vol.161
, pp. 1751-1762
-
-
Doberer, D.1
Haschemi, A.2
Andreas, M.3
Zapf, T.C.4
Clive, B.5
Jeitler, M.6
-
46
-
-
84918576943
-
Cell-type-specific downregulation of heme oxygenase-1 by lipopolysaccharide via Bach1 in primary human mononuclear cells
-
Dorresteijn, M. J., Paine, A., Zilian, E., Fenten, M. G., Frenzel, E., Janciauskiene, S., et al. (2015). Cell-type-specific downregulation of heme oxygenase-1 by lipopolysaccharide via Bach1 in primary human mononuclear cells. Free Radic. Biol. Med. 78, 224-232. doi: 10.1016/j.freeradbiomed.2014.10.579
-
(2015)
Free Radic. Biol. Med
, vol.78
, pp. 224-232
-
-
Dorresteijn, M.J.1
Paine, A.2
Zilian, E.3
Fenten, M.G.4
Frenzel, E.5
Janciauskiene, S.6
-
47
-
-
84907546730
-
Hemolysis-induced lethality involves inflammasome activation by heme
-
Dutra, F. F., Alves, L. S., Rodrigues, D., Fernandez, P. L., de Oliveira, R. B., Golenbock, D. T., et al. (2014). Hemolysis-induced lethality involves inflammasome activation by heme. Proc. Natl. Acad. Sci. U.S.A. 111, E4110-E4118. doi: 10.1073/pnas.1405023111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. E4110-E4118
-
-
Dutra, F.F.1
Alves, L.S.2
Rodrigues, D.3
Fernandez, P.L.4
de Oliveira, R.B.5
Golenbock, D.T.6
-
48
-
-
84904631113
-
Heme on innate immunity and inflammation
-
Dutra, F. F., and Bozza, M. T. (2014). Heme on innate immunity and inflammation. Front. Pharmacol. 5:115. doi: 10.3389/fphar.2014.00115
-
(2014)
Front. Pharmacol
, vol.5
, pp. 115
-
-
Dutra, F.F.1
Bozza, M.T.2
-
49
-
-
84990924505
-
Alterations in systemic extracellular heme and hemopexin are associated with adverse clinical outcomes in Ugandan children with severe malaria
-
Elphinstone, R. E., Conroy, A. L., Hawkes, M., Hermann, L., Namasopo, S., Warren, H. S., et al. (2016). Alterations in systemic extracellular heme and hemopexin are associated with adverse clinical outcomes in Ugandan children with severe malaria. J. Infect. Dis. 214, 1268-1275. doi: 10.1093/infdis/jiw357
-
(2016)
J. Infect. Dis
, vol.214
, pp. 1268-1275
-
-
Elphinstone, R.E.1
Conroy, A.L.2
Hawkes, M.3
Hermann, L.4
Namasopo, S.5
Warren, H.S.6
-
50
-
-
4644226200
-
The role of heme oxygenase-1 promoter polymorphisms in human disease
-
Exner, M., Minar, E., Wagner, O., and Schillinger, M. (2004). The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic. Biol. Med. 37, 1097-1104. doi: 10.1016/j.freeradbiomed.2004.07.008
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 1097-1104
-
-
Exner, M.1
Minar, E.2
Wagner, O.3
Schillinger, M.4
-
51
-
-
34547120742
-
Characterization of heme as activator of Toll-like receptor 4
-
Figueiredo, R. T., Fernandez, P. L., Mourao-Sa, D. S., Porto, B. N., Dutra, F. F., Alves, L. S., et al. (2007). Characterization of heme as activator of Toll-like receptor 4. J. Biol. Chem. 282, 20221-20229. doi: 10.1074/jbc.M610737200
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20221-20229
-
-
Figueiredo, R.T.1
Fernandez, P.L.2
Mourao-Sa, D.S.3
Porto, B.N.4
Dutra, F.F.5
Alves, L.S.6
-
52
-
-
84880923632
-
Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome
-
Frimat, M., Tabarin, F., Dimitrov, J. D., Poitou, C., Halbwachs-Mecarelli, L., Fremeaux-Bacchi, V. T., et al. (2013). Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome. Blood 122, 282-292. doi: 10.1182/blood-2013-03-489245
-
(2013)
Blood
, vol.122
, pp. 282-292
-
-
Frimat, M.1
Tabarin, F.2
Dimitrov, J.D.3
Poitou, C.4
Halbwachs-Mecarelli, L.5
Fremeaux-Bacchi, V.T.6
-
53
-
-
84887457415
-
Extracellular hemin crisis triggers acute chest syndrome in sickle mice
-
Ghosh, S., Adisa, O. A., Chappa, P., Tan, F., Jackson, K. A., Archer, D. R. Ofori-Acquah, et al. (2013). Extracellular hemin crisis triggers acute chest syndrome in sickle mice. J. Clin. Invest. 123, 4809-4820. doi: 10.1172/JCI64578
-
(2013)
J. Clin. Invest
, vol.123
, pp. 4809-4820
-
-
Ghosh, S.1
Adisa, O.A.2
Chappa, P.3
Tan, F.4
Jackson, K.A.5
Archer, D.R.O.-A.6
-
54
-
-
84877691626
-
Heme sensor proteins
-
Girvan, H. M., and Munro, A. W. (2013). Heme sensor proteins. J. Biol. Chem. 288, 13194-13203. doi: 10.1074/jbc.R112.422642
-
(2013)
J. Biol. Chem
, vol.288
, pp. 13194-13203
-
-
Girvan, H.M.1
Munro, A.W.2
-
55
-
-
0020696961
-
Hematin: unique effects of hemostasis
-
Glueck, R., Green, D., Cohen, I., and Ts'ao, C. H. (1983). Hematin: unique effects of hemostasis. Blood 61, 243-249
-
(1983)
Blood
, vol.61
, pp. 243-249
-
-
Glueck, R.1
Green, D.2
Cohen, I.3
Ts'ao, C.H.4
-
56
-
-
0022641654
-
Instability of hematin used in the treatment of acute hepatic porphyria
-
Goetsch, C. A., and Bissell, D. M. (1986). Instability of hematin used in the treatment of acute hepatic porphyria. N. Engl. J. Med. 315, 235-238. doi: 10.1056/NEJM198607243150406
-
(1986)
N. Engl. J. Med
, vol.315
, pp. 235-238
-
-
Goetsch, C.A.1
Bissell, D.M.2
-
57
-
-
84971320866
-
Sepsis: pathophysiology and clinical management
-
Gotts, J. E., and Matthay, M. A. (2016). Sepsis: pathophysiology and clinical management. BMJ 353:i1585. doi: 10.1136/bmj.i1585
-
(2016)
BMJ
, vol.353
-
-
Gotts, J.E.1
Matthay, M.A.2
-
58
-
-
77949525185
-
Mechanisms of cell protection by heme oxygenase-1
-
Gozzelino, R., Jeney, V., and Soares, M. P. (2010). Mechanisms of cell protection by heme oxygenase-1. Annu. Rev. Pharmacol. Toxicol. 50, 323-354. doi: 10.1146/annurev.pharmtox.010909.105600
-
(2010)
Annu. Rev. Pharmacol. Toxicol
, vol.50
, pp. 323-354
-
-
Gozzelino, R.1
Jeney, V.2
Soares, M.P.3
-
59
-
-
84924917774
-
Extracellular hemoglobin-mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage
-
Gram, M., Sveinsdottir, S., Cinthio, M., Sveinsdottir, K., Hansson, S. R., Morgelin, M., et al. (2014). Extracellular hemoglobin-mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage. J. Neuroinflammation 11:200. doi: 10.1186/s12974-014-0200-9
-
(2014)
J. Neuroinflammation
, vol.11
, pp. 200
-
-
Gram, M.1
Sveinsdottir, S.2
Cinthio, M.3
Sveinsdottir, K.4
Hansson, S.R.5
Morgelin, M.6
-
60
-
-
0016768918
-
Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition
-
Granick, S., Sinclair, P., Sassa, S., and Grieninger, G. (1975). Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition. J. Biol. Chem. 250, 9215-9225
-
(1975)
J. Biol. Chem
, vol.250
, pp. 9215-9225
-
-
Granick, S.1
Sinclair, P.2
Sassa, S.3
Grieninger, G.4
-
61
-
-
84983032429
-
Haptoglobin or hemopexin therapy prevents acute adverse effects of resuscitation after prolonged storage of red cells
-
Graw, J. A., Mayeur, C., Rosales, I., Liu, Y., Sabbisetti, V. S., Riley, F. E., et al. (2016). Haptoglobin or hemopexin therapy prevents acute adverse effects of resuscitation after prolonged storage of red cells. Circulation 134, 945-960. doi: 10.1161/CIRCULATIONAHA.115.019955
-
(2016)
Circulation
, vol.134
, pp. 945-960
-
-
Graw, J.A.1
Mayeur, C.2
Rosales, I.3
Liu, Y.4
Sabbisetti, V.S.5
Riley, F.E.6
-
62
-
-
84994659860
-
Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation
-
Greil, J., Verga-Falzacappa, M. V., Echner, N. E., Behnisch, W., Bandapalli, O. R., Pechanska, P., et al. (2016). Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation. Haematologica 101, e436-e439. doi: 10.3324/haematol.2016.147090
-
(2016)
Haematologica
, vol.101
, pp. e436-e439
-
-
Greil, J.1
Verga-Falzacappa, M.V.2
Echner, N.E.3
Behnisch, W.4
Bandapalli, O.R.5
Pechanska, P.6
-
63
-
-
0028833944
-
Haemoglobin-based blood substitutes and sepsis
-
Griffiths, E., Cortes, A., Gilbert, N., Stevenson, P., MacDonald, S., and Pepper, D. (1995). Haemoglobin-based blood substitutes and sepsis. Lancet 345, 158-160. doi: 10.1016/S0140-6736(95)90168-X
-
(1995)
Lancet
, vol.345
, pp. 158-160
-
-
Griffiths, E.1
Cortes, A.2
Gilbert, N.3
Stevenson, P.4
MacDonald, S.5
Pepper, D.6
-
64
-
-
8544284074
-
The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells
-
Grosser, N., Hemmerle, A., Berndt, G., Erdmann, K., Hinkelmann, U., Schurger, S., et al. (2004). The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells. Free Radic. Biol. Med. 37, 2064-2071. doi: 10.1016/j.freeradbiomed.2004.09.009
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 2064-2071
-
-
Grosser, N.1
Hemmerle, A.2
Berndt, G.3
Erdmann, K.4
Hinkelmann, U.5
Schurger, S.6
-
65
-
-
84899942981
-
Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation
-
Hada, H., Shiraki, T., Watanabe-Matsui, M., and Igarashi, K. (2014). Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation. Biochim. Biophys. Acta 1840, 2351-2360. doi: 10.1016/j.bbagen.2014.02.029
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 2351-2360
-
-
Hada, H.1
Shiraki, T.2
Watanabe-Matsui, M.3
Igarashi, K.4
-
66
-
-
84896366680
-
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages
-
Haldar, M., Kohyama, M., So, A. Y., Kc, W., Wu, X., Briseno, C. G., et al. (2014). Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell 156, 1223-1234. doi: 10.1016/j.cell.2014.01.069
-
(2014)
Cell
, vol.156
, pp. 1223-1234
-
-
Haldar, M.1
Kohyama, M.2
So, A.Y.3
Kc, W.4
Wu, X.5
Briseno, C.G.6
-
67
-
-
84864297704
-
One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans
-
Hamza, I., and Dailey, H. A. (2012). One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans. Biochim. Biophys. Acta 1823, 1617-1632. doi: 10.1016/j.bbamcr.2012.04.009
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 1617-1632
-
-
Hamza, I.1
Dailey, H.A.2
-
68
-
-
0020429882
-
Binding of heme by glutathione S-transferase: a possible role of the erythrocyte enzyme
-
Harvey, J. W., and Beutler, E. (1982). Binding of heme by glutathione S-transferase: a possible role of the erythrocyte enzyme. Blood 60, 1227-1230
-
(1982)
Blood
, vol.60
, pp. 1227-1230
-
-
Harvey, J.W.1
Beutler, E.2
-
69
-
-
0008239743
-
Accelerated autoxidation and heme loss due to instability of sickle hemoglobin
-
Hebbel, R. P., Morgan, W. T., Eaton, J. W., and Hedlund, B. E. (1988). Accelerated autoxidation and heme loss due to instability of sickle hemoglobin. Proc. Natl. Acad. Sci. U.S.A. 85, 237-241. doi: 10.1073/pnas.85.1.237
-
(1988)
Proc. Natl. Acad. Sci. U.S.A
, vol.85
, pp. 237-241
-
-
Hebbel, R.P.1
Morgan, W.T.2
Eaton, J.W.3
Hedlund, B.E.4
-
70
-
-
0025190892
-
Interleukin-6 and the acute phase response
-
Heinrich, P. C., Castell, J. V., and Andus, T. (1990). Interleukin-6 and the acute phase response. Biochem. J. 265, 621-636. doi: 10.1042/bj2650621
-
(1990)
Biochem. J
, vol.265
, pp. 621-636
-
-
Heinrich, P.C.1
Castell, J.V.2
Andus, T.3
-
71
-
-
38949193198
-
The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis
-
Horvath, K., Varga, C., Berko, A., Posa, A., Laszlo, F., and Whittle, B. J. (2008). The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis. Eur. J. Pharmacol. 581, 315-323. doi: 10.1016/j.ejphar.2007.12.004
-
(2008)
Eur. J. Pharmacol
, vol.581
, pp. 315-323
-
-
Horvath, K.1
Varga, C.2
Berko, A.3
Posa, A.4
Laszlo, F.5
Whittle, B.J.6
-
72
-
-
27144551314
-
Identification of the receptor scavenging hemopexin-heme complexes
-
Hvidberg, V., Maniecki, M. B., Jacobsen, C., Hojrup, P., Moller, H. J., and Moestrup, S. K. (2005). Identification of the receptor scavenging hemopexin-heme complexes. Blood 106, 2572-2579. doi: 10.1182/blood-2005-03-1185
-
(2005)
Blood
, vol.106
, pp. 2572-2579
-
-
Hvidberg, V.1
Maniecki, M.B.2
Jacobsen, C.3
Hojrup, P.4
Moller, H.J.5
Moestrup, S.K.6
-
73
-
-
0344862115
-
Differential cellular and subcellular localization of heme-binding protein 23/peroxiredoxin I and heme oxygenase-1 in rat liver
-
Immenschuh, S., Baumgart-Vogt, E., Tan, M., Iwahara, S., Ramadori, G., and Fahimi, H. D. (2003). Differential cellular and subcellular localization of heme-binding protein 23/peroxiredoxin I and heme oxygenase-1 in rat liver. J. Histochem. Cytochem. 51, 1621-1631. doi: 10.1177/002215540305101206
-
(2003)
J. Histochem. Cytochem
, vol.51
, pp. 1621-1631
-
-
Immenschuh, S.1
Baumgart-Vogt, E.2
Tan, M.3
Iwahara, S.4
Ramadori, G.5
Fahimi, H.D.6
-
74
-
-
0032528947
-
Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes
-
Immenschuh, S., Hinke, V., Ohlmann, A., Gifhorn-Katz, S., Katz, N., Jungermann, K., et al. (1998a). Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes. Biochem. J. 334(Pt 1), 141-146. doi: 10.1042/bj3340141
-
(1998)
Biochem. J
, vol.334
, pp. 141-146
-
-
Immenschuh, S.1
Hinke, V.2
Ohlmann, A.3
Gifhorn-Katz, S.4
Katz, N.5
Jungermann, K.6
-
75
-
-
0031956516
-
The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures
-
Immenschuh, S., Kietzmann, T., Hinke, V., Wiederhold, M., Katz, N., and Muller-Eberhard, U. (1998b). The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures. Mol. Pharmacol. 53, 483-491
-
(1998)
Mol. Pharmacol
, vol.53
, pp. 483-491
-
-
Immenschuh, S.1
Kietzmann, T.2
Hinke, V.3
Wiederhold, M.4
Katz, N.5
Muller-Eberhard, U.6
-
76
-
-
0028222522
-
The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms
-
Immenschuh, S., Nagae, Y., Satoh, H., Baumann, H., and Muller-Eberhard, U. (1994). The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms. J. Biol. Chem. 269, 12654-12661
-
(1994)
J. Biol. Chem
, vol.269
, pp. 12654-12661
-
-
Immenschuh, S.1
Nagae, Y.2
Satoh, H.3
Baumann, H.4
Muller-Eberhard, U.5
-
77
-
-
0034668216
-
Gene regulation of heme oxygenase-1 as a therapeutic target
-
Immenschuh, S., and Ramadori, G. (2000). Gene regulation of heme oxygenase-1 as a therapeutic target. Biochem. Pharmacol. 60, 1121-1128. doi: 10.1016/S0006-2952(00)00443-3
-
(2000)
Biochem. Pharmacol
, vol.60
, pp. 1121-1128
-
-
Immenschuh, S.1
Ramadori, G.2
-
78
-
-
0032921697
-
Nitric oxide mediates the lipopolysaccharide dependent upregulation of the heme oxygenase-1 gene expression in cultured rat Kupffer cells
-
Immenschuh, S., Tan, M., and Ramadori, G. (1999). Nitric oxide mediates the lipopolysaccharide dependent upregulation of the heme oxygenase-1 gene expression in cultured rat Kupffer cells. J. Hepatol. 30, 61-69. doi: 10.1016/S0168-8278(99)80008-7
-
(1999)
J. Hepatol
, vol.30
, pp. 61-69
-
-
Immenschuh, S.1
Tan, M.2
Ramadori, G.3
-
79
-
-
1842337282
-
Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin
-
Ingram, V. M. (1957). Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature 180, 326-328. doi: 10.1038/180326a0
-
(1957)
Nature
, vol.180
, pp. 326-328
-
-
Ingram, V.M.1
-
80
-
-
0028809676
-
Purification, characterization and cloning of a heme-binding protein (23kDa) in rat liver cytosol
-
Iwahara, S., Satoh, H., Song, D. X., Webb, J., Burlingame, A. L., Nagae, Y., et al. (1995). Purification, characterization and cloning of a heme-binding protein (23kDa) in rat liver cytosol. Biochemistry 34, 13398-13406. doi: 10.1021/bi00041a017
-
(1995)
Biochemistry
, vol.34
, pp. 13398-13406
-
-
Iwahara, S.1
Satoh, H.2
Song, D.X.3
Webb, J.4
Burlingame, A.L.5
Nagae, Y.6
-
81
-
-
84887391095
-
Association between haptoglobin, hemopexin and mortality in adults with sepsis
-
Janz, D. R., Bastarache, J. A., Sills, G., Wickersham, N., May, A. K., Bernard, G. R., et al. (2013). Association between haptoglobin, hemopexin and mortality in adults with sepsis. Crit. Care 17:R272. doi: 10.1186/cc13108
-
(2013)
Crit. Care
, vol.17
, pp. R272
-
-
Janz, D.R.1
Bastarache, J.A.2
Sills, G.3
Wickersham, N.4
May, A.K.5
Bernard, G.R.6
-
82
-
-
84908376176
-
Red blood cell, hemoglobin and heme in the progression of atherosclerosis
-
Jeney, V., Balla, G., and Balla, J. (2014). Red blood cell, hemoglobin and heme in the progression of atherosclerosis. Front. Physiol. 5:379. doi: 10.3389/fphys.2014.00379
-
(2014)
Front. Physiol
, vol.5
, pp. 379
-
-
Jeney, V.1
Balla, G.2
Balla, J.3
-
83
-
-
0036682472
-
Pro-oxidant and cytotoxic effects of circulating heme
-
Jeney, V., Balla, J., Yachie, A., Varga, Z., Vercellotti, G. M., Eaton, J. W., et al. (2002). Pro-oxidant and cytotoxic effects of circulating heme. Blood 100, 879-887. doi: 10.1182/blood.V100.3.879
-
(2002)
Blood
, vol.100
, pp. 879-887
-
-
Jeney, V.1
Balla, J.2
Yachie, A.3
Varga, Z.4
Vercellotti, G.M.5
Eaton, J.W.6
-
84
-
-
4344566310
-
Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse
-
Kapturczak, M. H., Wasserfall, C., Brusko, T., Campbell-Thompson, M., Ellis, T. M., Atkinson, M. A., et al. (2004). Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am. J. Pathol. 165, 1045-1053. doi: 10.1016/S0002-9440(10)63365-2
-
(2004)
Am. J. Pathol
, vol.165
, pp. 1045-1053
-
-
Kapturczak, M.H.1
Wasserfall, C.2
Brusko, T.3
Campbell-Thompson, M.4
Ellis, T.M.5
Atkinson, M.A.6
-
85
-
-
84866992460
-
Heme binding to human alpha-1 proteinase inhibitor
-
Karnaukhova, E., Krupnikova, S. S., Rajabi, M., and Alayash, A. I. (2012). Heme binding to human alpha-1 proteinase inhibitor. Biochim. Biophys. Acta 1820, 2020-2029. doi: 10.1016/j.bbagen.2012.09.012
-
(2012)
Biochim. Biophys. Acta
, vol.1820
, pp. 2020-2029
-
-
Karnaukhova, E.1
Krupnikova, S.S.2
Rajabi, M.3
Alayash, A.I.4
-
86
-
-
84942856730
-
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation
-
Keleku-Lukwete, N., Suzuki, M., Otsuki, A., Tsuchida, K., Katayama, S., Hayashi, M., et al. (2015). Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation. Proc. Natl. Acad. Sci. U.S.A. 112, 12169-12174. doi: 10.1073/pnas.1509158112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. 12169-12174
-
-
Keleku-Lukwete, N.1
Suzuki, M.2
Otsuki, A.3
Tsuchida, K.4
Katayama, S.5
Hayashi, M.6
-
87
-
-
84876958386
-
Heme levels are increased in human failing hearts
-
Khechaduri, A., Bayeva, M., Chang, H. C., and Ardehali, H. (2013). Heme levels are increased in human failing hearts. J. Am. Coll. Cardiol. 61, 1884-1893. doi: 10.1016/j.jacc.2013.02.012
-
(2013)
J. Am. Coll. Cardiol
, vol.61
, pp. 1884-1893
-
-
Khechaduri, A.1
Bayeva, M.2
Chang, H.C.3
Ardehali, H.4
-
88
-
-
0024429210
-
Changes of myocardial functions in acute hepatic porphyrias. Role of heme arginate administration
-
Kordac, V., Kozakova, M., and Martasek, P. (1989). Changes of myocardial functions in acute hepatic porphyrias. Role of heme arginate administration. Ann. Med. 21, 273-276. doi: 10.3109/07853898909149205
-
(1989)
Ann. Med
, vol.21
, pp. 273-276
-
-
Kordac, V.1
Kozakova, M.2
Martasek, P.3
-
89
-
-
78650676293
-
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution
-
Kovtunovych, G., Eckhaus, M. A., Ghosh, M. C., Ollivierre-Wilson, H., and Rouault, T. A. (2010). Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. Blood 116, 6054-6062. doi: 10.1182/blood-2010-03-272138
-
(2010)
Blood
, vol.116
, pp. 6054-6062
-
-
Kovtunovych, G.1
Eckhaus, M.A.2
Ghosh, M.C.3
Ollivierre-Wilson, H.4
Rouault, T.A.5
-
90
-
-
19444386445
-
Free heme toxicity and its detoxification systems in human
-
Kumar, S., and Bandyopadhyay, U. (2005). Free heme toxicity and its detoxification systems in human. Toxicol. Lett. 157, 175-188. doi: 10.1016/j.toxlet.2005.03.004
-
(2005)
Toxicol. Lett
, vol.157
, pp. 175-188
-
-
Kumar, S.1
Bandyopadhyay, U.2
-
91
-
-
0019887888
-
Purification and characterization of biliverdin reductase from rat liver
-
Kutty, R. K., and Maines, M. D. (1981). Purification and characterization of biliverdin reductase from rat liver. J. Biol. Chem. 256, 3956-3962
-
(1981)
J. Biol. Chem
, vol.256
, pp. 3956-3962
-
-
Kutty, R.K.1
Maines, M.D.2
-
92
-
-
84866046917
-
Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases
-
Larsen, R., Gouveia, Z., Soares, M. P., and Gozzelino, R. (2012). Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases. Front. Pharmacol. 3:77. doi: 10.3389/fphar.2012.00077
-
(2012)
Front. Pharmacol
, vol.3
, pp. 77
-
-
Larsen, R.1
Gouveia, Z.2
Soares, M.P.3
Gozzelino, R.4
-
93
-
-
77958023093
-
A central role for free heme in the pathogenesis of severe sepsis
-
Larsen, R., Gozzelino, R., Jeney, V., Tokaji, L., Bozza, F. A., Japiassu, A. M., et al. (2010). A central role for free heme in the pathogenesis of severe sepsis. Sci. Transl. Med. 2:51ra71. doi: 10.1126/scitranslmed.3001118
-
(2010)
Sci. Transl. Med
, vol.2
-
-
Larsen, R.1
Gozzelino, R.2
Jeney, V.3
Tokaji, L.4
Bozza, F.A.5
Japiassu, A.M.6
-
94
-
-
4444369432
-
Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection
-
Lee, T. S., Chang, C. C., Zhu, Y., and Shyy, J. Y. (2004). Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation 110, 1296-1302. doi: 10.1161/01.CIR.0000140694.67251.9C
-
(2004)
Circulation
, vol.110
, pp. 1296-1302
-
-
Lee, T.S.1
Chang, C.C.2
Zhu, Y.3
Shyy, J.Y.4
-
95
-
-
67649979539
-
Association between duration of storage of transfused red blood cells and morbidity and mortality in adult patients: myth or reality?
-
Lelubre, C., Piagnerelli, M., and Vincent, J. L. (2009). Association between duration of storage of transfused red blood cells and morbidity and mortality in adult patients: myth or reality? Transfusion 49, 1384-1394. doi: 10.1111/j.1537-2995.2009.02211.x
-
(2009)
Transfusion
, vol.49
, pp. 1384-1394
-
-
Lelubre, C.1
Piagnerelli, M.2
Vincent, J.L.3
-
96
-
-
84978842635
-
Heme oxygenase-1 in kidney health and disease
-
Lever, J. M., Boddu, R., George, J. F., and Agarwal, A. (2016). Heme oxygenase-1 in kidney health and disease. Antioxid. Redox Signal. 25, 165-183. doi: 10.1089/ars.2016.6659
-
(2016)
Antioxid. Redox Signal
, vol.25
, pp. 165-183
-
-
Lever, J.M.1
Boddu, R.2
George, J.F.3
Agarwal, A.4
-
97
-
-
0026032312
-
Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine
-
Levere, R. D., Gong, Y. F., Kappas, A., Bucher, D. J., Wormser, G. P., and Abraham, N. G. (1991). Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine. Proc. Natl. Acad. Sci. U.S.A. 88, 1756-1759. doi: 10.1073/pnas.88.5.1756
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 1756-1759
-
-
Levere, R.D.1
Gong, Y.F.2
Kappas, A.3
Bucher, D.J.4
Wormser, G.P.5
Abraham, N.G.6
-
98
-
-
35848961446
-
Pharmacologic induction of heme oxygenase-1
-
Li, C., Hossieny, P., Wu, B. J., Qawasmeh, A., Beck, K., and Stocker, R. (2007). Pharmacologic induction of heme oxygenase-1. Antioxid. Redox Signal. 9, 2227-2239. doi: 10.1089/ars.2007.1783
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 2227-2239
-
-
Li, C.1
Hossieny, P.2
Wu, B.J.3
Qawasmeh, A.4
Beck, K.5
Stocker, R.6
-
99
-
-
0028129625
-
Studies on the efflux of heme from biological membranes
-
Liem, H. H., Noy, N., and Muller-Eberhard, U. (1994). Studies on the efflux of heme from biological membranes. Biochim. Biophys. Acta 1194, 264-270. doi: 10.1016/0005-2736(94)90308-5
-
(1994)
Biochim. Biophys. Acta
, vol.1194
, pp. 264-270
-
-
Liem, H.H.1
Noy, N.2
Muller-Eberhard, U.3
-
100
-
-
77954699484
-
Synergistic inflammation is induced by blood degradation products with microbial Toll-like receptor agonists and is blocked by hemopexin
-
Lin, T., Kwak, Y. H., Sammy, F., He, P., Thundivalappil, S., Sun, G., et al. (2010). Synergistic inflammation is induced by blood degradation products with microbial Toll-like receptor agonists and is blocked by hemopexin. J. Infect. Dis. 202, 624-632. doi: 10.1086/654929
-
(2010)
J. Infect. Dis
, vol.202
, pp. 624-632
-
-
Lin, T.1
Kwak, Y.H.2
Sammy, F.3
He, P.4
Thundivalappil, S.5
Sun, G.6
-
101
-
-
84987680674
-
Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis
-
Lin, T., Liu, J., Huang, F., Van Engelen, T. S., Thundivalappil, S. R., Riley, F. E., et al. (2016). Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis. Mol. Med. 22, 22-31. doi: 10.2119/molmed.2016.00006
-
(2016)
Mol. Med
, vol.22
, pp. 22-31
-
-
Lin, T.1
Liu, J.2
Huang, F.3
Van Engelen, T.S.4
Thundivalappil, S.R.5
Riley, F.E.6
-
102
-
-
84929084330
-
Hemopexin in severe inflammation and infection: mouse models and human diseases
-
Lin, T., Maita, D., Thundivalappil, S. R., Riley, F. E., Hambsch, J., Van Marter, L. J., et al. (2015). Hemopexin in severe inflammation and infection: mouse models and human diseases. Crit. Care 19:166. doi: 10.1186/s13054-015-0885-x
-
(2015)
Crit. Care
, vol.19
, pp. 166
-
-
Lin, T.1
Maita, D.2
Thundivalappil, S.R.3
Riley, F.E.4
Hambsch, J.5
Van Marter, L.J.6
-
103
-
-
0006783917
-
Binding of haematin by human serum albumin
-
Little, H. N., and Neilands, J. B. (1960). Binding of haematin by human serum albumin. Nature 188, 913-915. doi: 10.1038/188913a0
-
(1960)
Nature
, vol.188
, pp. 913-915
-
-
Little, H.N.1
Neilands, J.B.2
-
104
-
-
84866051194
-
Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly?
-
Lundvig, D. M., Immenschuh, S., and Wagener, F. A. (2012). Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly? Front. Pharmacol. 3:81. doi: 10.3389/fphar.2012.00081
-
(2012)
Front. Pharmacol
, vol.3
, pp. 81
-
-
Lundvig, D.M.1
Immenschuh, S.2
Wagener, F.A.3
-
105
-
-
84957960233
-
Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage
-
Ma, B., Day, J. P., Phillips, H., Slootsky, B., Tolosano, E., and Dore, S. (2016). Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage. J. Neuroinflammation 13:26. doi: 10.1186/s12974-016-0490-1
-
(2016)
J. Neuroinflammation
, vol.13
, pp. 26
-
-
Ma, B.1
Day, J.P.2
Phillips, H.3
Slootsky, B.4
Tolosano, E.5
Dore, S.6
-
106
-
-
0030923630
-
The heme oxygenase system: a regulator of second messenger gases
-
Maines, M. D. (1997). The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37, 517-554. doi: 10.1146/annurev.pharmtox.37.1.517
-
(1997)
Annu. Rev. Pharmacol. Toxicol
, vol.37
, pp. 517-554
-
-
Maines, M.D.1
-
107
-
-
0006476631
-
Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity
-
Maines, M. D., and Kappas, A. (1974). Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity. Proc. Natl. Acad. Sci. U.S.A. 71, 4293-4297. doi: 10.1073/pnas.71.11.4293
-
(1974)
Proc. Natl. Acad. Sci. U.S.A
, vol.71
, pp. 4293-4297
-
-
Maines, M.D.1
Kappas, A.2
-
108
-
-
1542335553
-
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
-
Martin, D., Rojo, A. I., Salinas, M., Diaz, R., Gallardo, G., Alam, J., et al. (2004). Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J. Biol. Chem. 279, 8919-8929. doi: 10.1074/jbc.M309660200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
-
109
-
-
84860798758
-
Association between the haptoglobin and heme oxygenase 1 genetic profiles and soluble CD163 in susceptibility to and severity of human malaria
-
Mendonca, V. R., Luz, N. F., Santos, N. J., Borges, V. M., Goncalves, M. S., Andrade, B. B., et al. (2012). Association between the haptoglobin and heme oxygenase 1 genetic profiles and soluble CD163 in susceptibility to and severity of human malaria. Infect. Immun. 80, 1445-1454. doi: 10.1128/IAI.05933-11
-
(2012)
Infect. Immun
, vol.80
, pp. 1445-1454
-
-
Mendonca, V.R.1
Luz, N.F.2
Santos, N.J.3
Borges, V.M.4
Goncalves, M.S.5
Andrade, B.B.6
-
110
-
-
33747453769
-
Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases
-
Mense, S. M., and Zhang, L. (2006). Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases. Cell Res. 16, 681-692. doi: 10.1038/sj.cr.7310086
-
(2006)
Cell Res
, vol.16
, pp. 681-692
-
-
Mense, S.M.1
Zhang, L.2
-
111
-
-
1342303482
-
Of mice and not men: differences between mouse and human immunology
-
Mestas, J., and Hughes, C. C. (2004). Of mice and not men: differences between mouse and human immunology. J. Immunol. 172, 2731-2738. doi: 10.4049/jimmunol.172.5.2731
-
(2004)
J. Immunol
, vol.172
, pp. 2731-2738
-
-
Mestas, J.1
Hughes, C.C.2
-
112
-
-
0037034017
-
The pathogenic basis of malaria
-
Miller, L. H., Baruch, D. I., Marsh, K., and Doumbo, O. K. (2002). The pathogenic basis of malaria. Nature 415, 673-679. doi: 10.1038/415673a
-
(2002)
Nature
, vol.415
, pp. 673-679
-
-
Miller, L.H.1
Baruch, D.I.2
Marsh, K.3
Doumbo, O.K.4
-
113
-
-
77954152197
-
Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1
-
Miyazaki, T., Kirino, Y., Takeno, M., Samukawa, S., Hama, M., Tanaka, M., et al. (2010). Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. Cancer Sci. 101, 1409-1416. doi: 10.1111/j.1349-7006.2010.01550.x
-
(2010)
Cancer Sci
, vol.101
, pp. 1409-1416
-
-
Miyazaki, T.1
Kirino, Y.2
Takeno, M.3
Samukawa, S.4
Hama, M.5
Tanaka, M.6
-
114
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser, D. M., and Edwards, J. P. (2008). Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969. doi: 10.1038/nri2448
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
115
-
-
84893116938
-
Heme oxygenase-1 as a target for drug discovery
-
Motterlini, R., and Foresti, R. (2014). Heme oxygenase-1 as a target for drug discovery. Antioxid. Redox Signal. 20, 1810-1826. doi: 10.1089/ars.2013.5658
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 1810-1826
-
-
Motterlini, R.1
Foresti, R.2
-
116
-
-
0014942908
-
Hemopexin
-
Muller Eberhard, U. (1970). Hemopexin. N. Engl. J. Med. 283, 1090-1094. doi: 10.1056/NEJM197011122832007
-
(1970)
N. Engl. J. Med
, vol.283
, pp. 1090-1094
-
-
Muller Eberhard, U.1
-
117
-
-
37049045279
-
Immunoelectrophoretic studies of the beta1-haem-binding globulin (haemopexin) in hereditary haemolytic disorders
-
Muller-Eberhard, U., and Cleve, H. (1963). Immunoelectrophoretic studies of the beta1-haem-binding globulin (haemopexin) in hereditary haemolytic disorders. Nature 197, 602-603. doi: 10.1038/197602a0
-
(1963)
Nature
, vol.197
, pp. 602-603
-
-
Muller-Eberhard, U.1
Cleve, H.2
-
118
-
-
0014360531
-
Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases
-
Muller-Eberhard, U., Javid, J., Liem, H. H., Hanstein, A., and Hanna, M. (1968). Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases. Blood 32, 811-815
-
(1968)
Blood
, vol.32
, pp. 811-815
-
-
Muller-Eberhard, U.1
Javid, J.2
Liem, H.H.3
Hanstein, A.4
Hanna, M.5
-
119
-
-
0024564551
-
Transport of tetrapyrroles by proteins
-
Muller Eberhard, U., and Nikkilä, H. (1989). Transport of tetrapyrroles by proteins. Semin. Hematol. 26, 86-104
-
(1989)
Semin. Hematol
, vol.26
, pp. 86-104
-
-
Muller Eberhard, U.1
Nikkilä, H.2
-
120
-
-
0022520663
-
Haem arginate in the treatment of acute hepatic porphyrias
-
Mustajoki, P., Tenhunen, R., Tokola, O., and Gothoni, G. (1986). Haem arginate in the treatment of acute hepatic porphyrias. Br. Med. J. (Clin. Res. Ed.) 293, 538-539. doi: 10.1136/bmj.293.6546.538-a
-
(1986)
Br. Med. J. (Clin. Res. Ed.)
, vol.293
, pp. 538-539
-
-
Mustajoki, P.1
Tenhunen, R.2
Tokola, O.3
Gothoni, G.4
-
121
-
-
77953961138
-
Red cells, hemoglobin, heme, iron, and atherogenesis
-
Nagy, E., Eaton, J. W., Jeney, V., Soares, M. P., Varga, Z., Galajda, Z., et al. (2010). Red cells, hemoglobin, heme, iron, and atherogenesis. Arterioscler. Thromb. Vasc. Biol. 30, 1347-1353. doi: 10.1161/ATVBAHA.110.206433
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, pp. 1347-1353
-
-
Nagy, E.1
Eaton, J.W.2
Jeney, V.3
Soares, M.P.4
Varga, Z.5
Galajda, Z.6
-
122
-
-
27644520123
-
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction
-
Nakamichi, I., Habtezion, A., Zhong, B., Contag, C. H., Butcher, E. C., and Omary, M. B. (2005). Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction. J. Clin. Invest. 115, 3007-3014. doi: 10.1172/JCI24912
-
(2005)
J. Clin. Invest
, vol.115
, pp. 3007-3014
-
-
Nakamichi, I.1
Habtezion, A.2
Zhong, B.3
Contag, C.H.4
Butcher, E.C.5
Omary, M.B.6
-
123
-
-
0026755754
-
Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat
-
Nath, K. A., Balla, G., Vercellotti, G. M., Balla, J., Jacob, H. S., Levitt, M. D., et al. (1992). Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J. Clin. Invest. 90, 267-270. doi: 10.1172/JCI115847
-
(1992)
J. Clin. Invest
, vol.90
, pp. 267-270
-
-
Nath, K.A.1
Balla, G.2
Vercellotti, G.M.3
Balla, J.4
Jacob, H.S.5
Levitt, M.D.6
-
124
-
-
0028900182
-
Heme protein-mediated renal injury: a protective role for 21-aminosteroids in vitro and in vivo
-
Nath, K. A., Balla, J., Croatt, A. J., and Vercellotti, G. M. (1995). Heme protein-mediated renal injury: a protective role for 21-aminosteroids in vitro and in vivo. Kidney Int. 47, 592-602. doi: 10.1038/ki.1995.75
-
(1995)
Kidney Int
, vol.47
, pp. 592-602
-
-
Nath, K.A.1
Balla, J.2
Croatt, A.J.3
Vercellotti, G.M.4
-
125
-
-
84860633221
-
Vasculature and kidney complications in sickle cell disease
-
Nath, K. A., and Katusic, Z. S. (2012). Vasculature and kidney complications in sickle cell disease. J. Am. Soc. Nephrol. 23, 781-784. doi: 10.1681/ASN.2011101019
-
(2012)
J. Am. Soc. Nephrol
, vol.23
, pp. 781-784
-
-
Nath, K.A.1
Katusic, Z.S.2
-
126
-
-
66449100734
-
The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways
-
Ndisang, J. F., Lane, N., and Jadhav, A. (2009). The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways. Endocrinology 150, 2098-2108. doi: 10.1210/en.2008-0239
-
(2009)
Endocrinology
, vol.150
, pp. 2098-2108
-
-
Ndisang, J.F.1
Lane, N.2
Jadhav, A.3
-
127
-
-
0029410648
-
Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1
-
Otterbein, L., Sylvester, S. L., and Choi, A. M. (1995). Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. Am. J. Respir. Cell Mol. Biol. 13, 595-601. doi: 10.1165/ajrcmb.13.5.7576696
-
(1995)
Am. J. Respir. Cell Mol. Biol
, vol.13
, pp. 595-601
-
-
Otterbein, L.1
Sylvester, S.L.2
Choi, A.M.3
-
128
-
-
78049442406
-
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
-
Paine, A., Eiz-Vesper, B., Blasczyk, R., and Immenschuh, S. (2010). Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem. Pharmacol. 80, 1895-1903. doi: 10.1016/j.bcp.2010.07.014
-
(2010)
Biochem. Pharmacol
, vol.80
, pp. 1895-1903
-
-
Paine, A.1
Eiz-Vesper, B.2
Blasczyk, R.3
Immenschuh, S.4
-
129
-
-
34250008488
-
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
-
Pamplona, A., Ferreira, A., Balla, J., Jeney, V., Balla, G., Epiphanio, S., et al. (2007). Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat. Med. 13, 703-710. doi: 10.1038/nm1586
-
(2007)
Nat. Med
, vol.13
, pp. 703-710
-
-
Pamplona, A.1
Ferreira, A.2
Balla, J.3
Jeney, V.4
Balla, G.5
Epiphanio, S.6
-
130
-
-
0032825215
-
Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two β-propeller domains
-
Paoli, M., Anderson, B. F., Baker, H. M., Morgan, W. T., Smith, A., Baker, E., et al. (1999). Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two β-propeller domains. Nat. Struct. Biol. 6, 926-931. doi: 10.1038/13294
-
(1999)
Nat. Struct. Biol
, vol.6
, pp. 926-931
-
-
Paoli, M.1
Anderson, B.F.2
Baker, H.M.3
Morgan, W.T.4
Smith, A.5
Baker, E.6
-
131
-
-
20444472459
-
Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis
-
Paul, G., Bataille, F., Obermeier, F., Bock, J., Klebl, F., Strauch, U., et al. (2005). Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis. Clin. Exp. Immunol. 140, 547-555. doi: 10.1111/j.1365-2249.2005.02775.x
-
(2005)
Clin. Exp. Immunol
, vol.140
, pp. 547-555
-
-
Paul, G.1
Bataille, F.2
Obermeier, F.3
Bock, J.4
Klebl, F.5
Strauch, U.6
-
132
-
-
84920287987
-
Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease
-
Pechlaner, R., Willeit, P., Summerer, M., Santer, P., Egger, G., Kronenberg, F., et al. (2015). Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease. Arterioscler. Thromb. Vasc. Biol. 35, 229-236. doi: 10.1161/ATVBAHA.114.304729
-
(2015)
Arterioscler. Thromb. Vasc. Biol
, vol.35
, pp. 229-236
-
-
Pechlaner, R.1
Willeit, P.2
Summerer, M.3
Santer, P.4
Egger, G.5
Kronenberg, F.6
-
133
-
-
83755225193
-
Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys
-
Petersen, B., Ramackers, W., Lucas-Hahn, A., Lemme, E., Hassel, P., Queisser, A. L., et al. (2011). Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys. Xenotransplantation 18, 355-368. doi: 10.1111/j.1399-3089.2011.00674.x
-
(2011)
Xenotransplantation
, vol.18
, pp. 355-368
-
-
Petersen, B.1
Ramackers, W.2
Lucas-Hahn, A.3
Lemme, E.4
Hassel, P.5
Queisser, A.L.6
-
134
-
-
67650555703
-
The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
-
Peterson, S. J., Kim, D. H., Li, M., Positano, V., Vanella, L., Rodella, L. F., et al. (2009). The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. J. Lipid Res. 50, 1293-1304. doi: 10.1194/jlr.M800610-JLR200
-
(2009)
J. Lipid Res
, vol.50
, pp. 1293-1304
-
-
Peterson, S.J.1
Kim, D.H.2
Li, M.3
Positano, V.4
Vanella, L.5
Rodella, L.F.6
-
135
-
-
66149102423
-
Mechanisms of endothelial dysfunction, injury, and death
-
Pober, J. S., Min, W., and Bradley, J. R. (2009). Mechanisms of endothelial dysfunction, injury, and death. Annu. Rev. Pathol. 4, 71-95. doi: 10.1146/annurev.pathol.4.110807.092155
-
(2009)
Annu. Rev. Pathol
, vol.4
, pp. 71-95
-
-
Pober, J.S.1
Min, W.2
Bradley, J.R.3
-
136
-
-
0025158578
-
IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP
-
Poli, V., Mancini, F. P., and Cortese, R. (1990). IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell 63, 643-653. doi: 10.1016/0092-8674(90)90459-R
-
(1990)
Cell
, vol.63
, pp. 643-653
-
-
Poli, V.1
Mancini, F.P.2
Cortese, R.3
-
137
-
-
0031028178
-
Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells
-
Ponka, P. (1997). Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells. Blood 89, 1-25
-
(1997)
Blood
, vol.89
, pp. 1-25
-
-
Ponka, P.1
-
138
-
-
0033511832
-
Cell biology of heme
-
Ponka, P. (1999). Cell biology of heme. Am. J. Med. Sci. 318, 241-256. doi: 10.1016/S0002-9629(15)40628-7
-
(1999)
Am. J. Med. Sci
, vol.318
, pp. 241-256
-
-
Ponka, P.1
-
139
-
-
0028880959
-
Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice
-
Poss, K. D., Thomas, M. J., Ebralidze, A. K., O'Dell, T. J., and Tonegawa, S. (1995). Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice. Neuron 15, 867-873. doi: 10.1016/0896-6273(95)90177-9
-
(1995)
Neuron
, vol.15
, pp. 867-873
-
-
Poss, K.D.1
Thomas, M.J.2
Ebralidze, A.K.3
O'Dell, T.J.4
Tonegawa, S.5
-
140
-
-
0030886054
-
Reduced stress defense in heme oxygenase 1-deficient cells
-
Poss, K. D., and Tonegawa, S. (1997a). Reduced stress defense in heme oxygenase 1-deficient cells. Proc. Natl. Acad. Sci. U.S.A. 94, 10925-10930. doi: 10.1073/pnas.94.20.10925
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 10925-10930
-
-
Poss, K.D.1
Tonegawa, S.2
-
141
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
Poss, K. D., and Tonegawa, S. (1997b). Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl. Acad. Sci. U.S.A. 94, 10919-10924. doi: 10.1073/pnas.94.20.10919
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
142
-
-
0027234540
-
In vivo fate of hemopexin and heme-hemopexin complexes in the rat
-
Potter, D., Chroneos, Z. C., Baynes, J. W., Sinclair, P. R., Gorman, N., Liem, H. H., et al. (1993). In vivo fate of hemopexin and heme-hemopexin complexes in the rat. Arch. Biochem. Biophys. 300, 98-104. doi: 10.1006/abbi.1993.1014
-
(1993)
Arch. Biochem. Biophys
, vol.300
, pp. 98-104
-
-
Potter, D.1
Chroneos, Z.C.2
Baynes, J.W.3
Sinclair, P.R.4
Gorman, N.5
Liem, H.H.6
-
143
-
-
77955880548
-
The redox activity of hemoglobins: from physiologic functions to pathologic mechanisms
-
Reeder, B. J. (2010). The redox activity of hemoglobins: from physiologic functions to pathologic mechanisms. Antioxid. Redox Signal. 13, 1087-1123. doi: 10.1089/ars.2009.2974
-
(2010)
Antioxid. Redox Signal
, vol.13
, pp. 1087-1123
-
-
Reeder, B.J.1
-
144
-
-
84876892476
-
Hemoglobin redox reactions and red blood cell aging
-
Rifkind, J. M., and Nagababu, E. (2013). Hemoglobin redox reactions and red blood cell aging. Antioxid. Redox Signal. 18, 2274-2283. doi: 10.1089/ars.2012.4867
-
(2013)
Antioxid. Redox Signal
, vol.18
, pp. 2274-2283
-
-
Rifkind, J.M.1
Nagababu, E.2
-
145
-
-
84959086910
-
Heme: modulator of plasma systems in hemolytic diseases
-
Roumenina, L. T., Rayes, J., Lacroix-Desmazes, S., and Dimitrov, J. D. (2016). Heme: modulator of plasma systems in hemolytic diseases. Trends Mol. Med. 22, 200-213. doi: 10.1016/j.molmed.2016.01.004
-
(2016)
Trends Mol. Med
, vol.22
, pp. 200-213
-
-
Roumenina, L.T.1
Rayes, J.2
Lacroix-Desmazes, S.3
Dimitrov, J.D.4
-
146
-
-
33645945014
-
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
-
Ryter, S. W., Alam, J., and Choi, A. M. (2006). Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol. Rev. 86, 583-650. doi: 10.1152/physrev.00011.2005
-
(2006)
Physiol. Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
147
-
-
0033973712
-
The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro-and antioxidant properties
-
Ryter, S. W., and Tyrrell, R. M. (2000). The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro-and antioxidant properties. Free Radic. Biol. Med. 28, 289-309. doi: 10.1016/S0891-5849(99)00223-3
-
(2000)
Free Radic. Biol. Med
, vol.28
, pp. 289-309
-
-
Ryter, S.W.1
Tyrrell, R.M.2
-
148
-
-
0023128975
-
Hemoglobin potentiates central nervous system damage
-
Sadrzadeh, S. M., Anderson, D. K., Panter, S. S., Hallaway, P. E., and Eaton, J. W. (1987). Hemoglobin potentiates central nervous system damage. J. Clin. Invest. 79, 662-664. doi: 10.1172/JCI112865
-
(1987)
J. Clin. Invest
, vol.79
, pp. 662-664
-
-
Sadrzadeh, S.M.1
Anderson, D.K.2
Panter, S.S.3
Hallaway, P.E.4
Eaton, J.W.5
-
149
-
-
84901917580
-
PECAM-1-dependent heme oxygenase-1 regulation via an Nrf2-mediated pathway in endothelial cells
-
Saragih, H., Zilian, E., Jaimes, Y., Paine, A., Figueiredo, C., Eiz-Vesper, B., et al. (2014). PECAM-1-dependent heme oxygenase-1 regulation via an Nrf2-mediated pathway in endothelial cells. Thromb. Haemost. 111, 1077-1088. doi: 10.1160/TH13-11-0923
-
(2014)
Thromb. Haemost
, vol.111
, pp. 1077-1088
-
-
Saragih, H.1
Zilian, E.2
Jaimes, Y.3
Paine, A.4
Figueiredo, C.5
Eiz-Vesper, B.6
-
150
-
-
0028068784
-
Roles of heme iron-coordinating histidine residues of human hemopexin expressed in baculovirus-infected insect cells
-
Satoh, T., Satoh, H., Iwahara, S., Hrkal, Z., Peyton, D. H., and Muller-Eberhard, U. (1994). Roles of heme iron-coordinating histidine residues of human hemopexin expressed in baculovirus-infected insect cells. Proc. Natl. Acad. Sci. U.S.A. 91, 8423-8427. doi: 10.1073/pnas.91.18.8423
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 8423-8427
-
-
Satoh, T.1
Satoh, H.2
Iwahara, S.3
Hrkal, Z.4
Peyton, D.H.5
Muller-Eberhard, U.6
-
151
-
-
84973920862
-
Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury
-
Sawicki, K. T., Shang, M., Wu, R., Chang, H. C., Khechaduri, A., Sato, T., et al. (2015). Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury. J. Am. Heart Assoc. 4:e002272. doi: 10.1161/JAHA.115.002272
-
(2015)
J. Am. Heart Assoc
, vol.4
-
-
Sawicki, K.T.1
Shang, M.2
Wu, R.3
Chang, H.C.4
Khechaduri, A.5
Sato, T.6
-
152
-
-
70149120896
-
The susceptibility of mice to bacterial endotoxins
-
Schaedler, R. W., and Dubos, R. J. (1961). The susceptibility of mice to bacterial endotoxins. J. Exp. Med. 113, 559-570. doi: 10.1084/jem.113.3.559
-
(1961)
J. Exp. Med
, vol.113
, pp. 559-570
-
-
Schaedler, R.W.1
Dubos, R.J.2
-
153
-
-
84874439878
-
Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins
-
Schaer, D. J., Buehler, P. W., Alayash, A. I., Belcher, J. D., and Vercellotti, G. M. (2012). Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins. Blood 121, 1276-1284. doi: 10.1182/blood-2012-11-451229
-
(2012)
Blood
, vol.121
, pp. 1276-1284
-
-
Schaer, D.J.1
Buehler, P.W.2
Alayash, A.I.3
Belcher, J.D.4
Vercellotti, G.M.5
-
154
-
-
84908373728
-
Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development
-
Schaer, D. J., Vinchi, F., Ingoglia, G., Tolosano, E., and Buehler, P. W. (2014). Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development. Front. Physiol. 5:415. doi: 10.3389/fphys.2014.00415
-
(2014)
Front. Physiol
, vol.5
, pp. 415
-
-
Schaer, D.J.1
Vinchi, F.2
Ingoglia, G.3
Tolosano, E.4
Buehler, P.W.5
-
155
-
-
70349448718
-
Heme oxygenase-1 affords protection against noncerebral forms of severe malaria
-
Seixas, E., Gozzelino, R., Chora, A., Ferreira, A., Silva, G., Larsen, R., et al. (2009). Heme oxygenase-1 affords protection against noncerebral forms of severe malaria. Proc. Natl. Acad. Sci. U.S.A. 106, 15837-15842. doi: 10.1073/pnas.0903419106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 15837-15842
-
-
Seixas, E.1
Gozzelino, R.2
Chora, A.3
Ferreira, A.4
Silva, G.5
Larsen, R.6
-
156
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., et al. (2013). Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc. Natl. Acad. Sci. U.S.A. 110, 3507-3512. doi: 10.1073/pnas.1222878110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
Mindrinos, M.N.4
Baker, H.V.5
Xu, W.6
-
157
-
-
84884301455
-
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1
-
Shen, Y., Ward, N. C., Hodgson, J. M., Puddey, I. B., Wang, Y., Zhang, D., et al. (2013). Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1. Free Radic. Biol. Med. 65, 908-915. doi: 10.1016/j.freeradbiomed.2013.08.185
-
(2013)
Free Radic. Biol. Med
, vol.65
, pp. 908-915
-
-
Shen, Y.1
Ward, N.C.2
Hodgson, J.M.3
Puddey, I.B.4
Wang, Y.5
Zhang, D.6
-
158
-
-
1242284460
-
The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury
-
Sikorski, E. M., Hock, T., Hill-Kapturczak, N., and Agarwal, A. (2004). The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury. Am. J. Physiol. Renal Physiol. 286, F425-F441. doi: 10.1152/ajprenal.00297.2003
-
(2004)
Am. J. Physiol. Renal Physiol
, vol.286
, pp. F425-F441
-
-
Sikorski, E.M.1
Hock, T.2
Hill-Kapturczak, N.3
Agarwal, A.4
-
159
-
-
0023755912
-
Thrombophlebitis and disturbed hemostasis following administration of intravenous hematin in normal volunteers
-
Simionatto, C. S., Cabal, R., Jones, R. L., and Galbraith, R. A. (1988). Thrombophlebitis and disturbed hemostasis following administration of intravenous hematin in normal volunteers. Am. J. Med. 85, 538-540. doi: 10.1016/S0002-9343(88)80092-5
-
(1988)
Am. J. Med
, vol.85
, pp. 538-540
-
-
Simionatto, C.S.1
Cabal, R.2
Jones, R.L.3
Galbraith, R.A.4
-
160
-
-
84940029623
-
Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders
-
Smith, A., and McCulloh, R. J. (2015). Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders. Front. Physiol. 6:187. doi: 10.3389/fphys.2015.00187
-
(2015)
Front. Physiol
, vol.6
, pp. 187
-
-
Smith, A.1
McCulloh, R.J.2
-
161
-
-
84951922225
-
Red alert: labile heme is an alarmin
-
Soares, M. P., and Bozza, M. T. (2016). Red alert: labile heme is an alarmin. Curr. Opin. Immunol. 38, 94-100. doi: 10.1016/j.coi.2015.11.006
-
(2016)
Curr. Opin. Immunol
, vol.38
, pp. 94-100
-
-
Soares, M.P.1
Bozza, M.T.2
-
162
-
-
0026098841
-
Long-term intercalation of residual hemin in erythrocyte membranes distorts the cell
-
Solar, I., Muller-Eberhard, U., Shviro, Y., and Shaklai, N. (1991). Long-term intercalation of residual hemin in erythrocyte membranes distorts the cell. Biochim. Biophys. Acta 1062, 51-58. doi: 10.1016/0005-2736(91)90334-5
-
(1991)
Biochim. Biophys. Acta
, vol.1062
, pp. 51-58
-
-
Solar, I.1
Muller-Eberhard, U.2
Shviro, Y.3
Shaklai, N.4
-
163
-
-
84884884530
-
Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1
-
Son, Y., Lee, J. H., Chung, H. T., and Pae, H. O. (2013). Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxid. Med. Cell Longev. 2013:639541. doi: 10.1155/2013/639541
-
(2013)
Oxid. Med. Cell Longev
, vol.2013
-
-
Son, Y.1
Lee, J.H.2
Chung, H.T.3
Pae, H.O.4
-
164
-
-
79953320619
-
Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice
-
Spiller, F., Costa, C., Souto, F. O., Vinchi, F., Mestriner, F. L., Laure, H. J., et al. (2011). Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice. Am. J. Respir. Crit. Care Med. 183, 922-931. doi: 10.1164/rccm.201002-0223OC
-
(2011)
Am. J. Respir. Crit. Care Med
, vol.183
, pp. 922-931
-
-
Spiller, F.1
Costa, C.2
Souto, F.O.3
Vinchi, F.4
Mestriner, F.L.5
Laure, H.J.6
-
165
-
-
84935004948
-
Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage
-
Stapley, R., Rodriguez, C., Oh, J. Y., Honavar, J., Brandon, A., Wagener, B. M., et al. (2015). Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage. Free Radic. Biol. Med. 85, 207-218. doi: 10.1016/j.freeradbiomed.2015.04.025
-
(2015)
Free Radic. Biol. Med
, vol.85
, pp. 207-218
-
-
Stapley, R.1
Rodriguez, C.2
Oh, J.Y.3
Honavar, J.4
Brandon, A.5
Wagener, B.M.6
-
166
-
-
0032553305
-
Molecular characterization of a newly identified heme-binding protein induced during differentiation of murine erythroleukemia cells
-
Taketani, S., Adachi, Y., Kohno, H., Ikehara, S., Tokunaga, R., and Ishii, T. (1998). Molecular characterization of a newly identified heme-binding protein induced during differentiation of murine erythroleukemia cells. J. Biol. Chem. 273, 31388-31394. doi: 10.1074/jbc.273.47.31388
-
(1998)
J. Biol. Chem
, vol.273
, pp. 31388-31394
-
-
Taketani, S.1
Adachi, Y.2
Kohno, H.3
Ikehara, S.4
Tokunaga, R.5
Ishii, T.6
-
167
-
-
0014348401
-
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
-
Tenhunen, R., Marver, H. S., and Schmid, R. (1968). The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. U.S.A. 61, 748-755. doi: 10.1073/pnas.61.2.748
-
(1968)
Proc. Natl. Acad. Sci. U.S.A
, vol.61
, pp. 748-755
-
-
Tenhunen, R.1
Marver, H.S.2
Schmid, R.3
-
168
-
-
84952334326
-
Hemin preconditioning upregulates heme oxygenase-1 in deceased donor renal transplant recipients: a randomized, controlled, phase IIB trial
-
Thomas, R. A., Czopek, A., Bellamy, C. O., McNally, S. J., Kluth, D. C., and Marson, L. P. (2016). Hemin preconditioning upregulates heme oxygenase-1 in deceased donor renal transplant recipients: a randomized, controlled, phase IIB trial. Transplantation 100, 176-183. doi: 10.1097/TP.0000000000000770
-
(2016)
Transplantation
, vol.100
, pp. 176-183
-
-
Thomas, R.A.1
Czopek, A.2
Bellamy, C.O.3
McNally, S.J.4
Kluth, D.C.5
Marson, L.P.6
-
169
-
-
0036259938
-
Hemopexin: structure, function, and regulation
-
Tolosano, E., and Altruda, F. (2002). Hemopexin: structure, function, and regulation. DNA Cell Biol. 21, 297-306. doi: 10.1089/104454902753759717
-
(2002)
DNA Cell Biol
, vol.21
, pp. 297-306
-
-
Tolosano, E.1
Altruda, F.2
-
170
-
-
0036893587
-
Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis
-
Tolosano, E., Fagoonee, S., Hirsch, E., Berger, F. G., Baumann, H., Silengo, L., et al. (2002). Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis. Blood 100, 4201-4208. doi: 10.1182/blood-2002-04-1270
-
(2002)
Blood
, vol.100
, pp. 4201-4208
-
-
Tolosano, E.1
Fagoonee, S.2
Hirsch, E.3
Berger, F.G.4
Baumann, H.5
Silengo, L.6
-
171
-
-
77949497609
-
Heme scavenging and the other facets of hemopexin
-
Tolosano, E., Fagoonee, S., Morello, N., Vinchi, F., and Fiorito, V. (2010). Heme scavenging and the other facets of hemopexin. Antioxid. Redox Signal. 12, 305-320. doi: 10.1089/ars.2009.2787
-
(2010)
Antioxid. Redox Signal
, vol.12
, pp. 305-320
-
-
Tolosano, E.1
Fagoonee, S.2
Morello, N.3
Vinchi, F.4
Fiorito, V.5
-
172
-
-
0033485566
-
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice
-
Tolosano, E., Hirsch, E., Patrucco, E., Camaschella, C., Navone, R., Silengo, L., et al. (1999). Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood 94, 3906-3914
-
(1999)
Blood
, vol.94
, pp. 3906-3914
-
-
Tolosano, E.1
Hirsch, E.2
Patrucco, E.3
Camaschella, C.4
Navone, R.5
Silengo, L.6
-
173
-
-
33846664696
-
Physiology and pathophysiology of heme: implications for kidney disease
-
Tracz, M. J., Alam, J., and Nath, K. A. (2007). Physiology and pathophysiology of heme: implications for kidney disease. J. Am. Soc. Nephrol. 18, 414-420. doi: 10.1681/ASN.2006080894
-
(2007)
J. Am. Soc. Nephrol
, vol.18
, pp. 414-420
-
-
Tracz, M.J.1
Alam, J.2
Nath, K.A.3
-
174
-
-
0022977615
-
Purification and characterization of the major constitutive form of testicular heme oxygenase
-
Trakshel, G. M., Kutty, R. K., and Maines, M. D. (1986). Purification and characterization of the major constitutive form of testicular heme oxygenase. The noninducible isoform. J. Biol. Chem. 261, 11131-11137
-
(1986)
The noninducible isoform. J. Biol. Chem
, vol.261
, pp. 11131-11137
-
-
Trakshel, G.M.1
Kutty, R.K.2
Maines, M.D.3
-
175
-
-
37349070339
-
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide
-
True, A. L., Olive, M., Boehm, M., San, H., Westrick, R. J., Raghavachari, N., et al. (2007). Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide. Circ. Res. 101, 893-901. doi: 10.1161/CIRCRESAHA.107.158998
-
(2007)
Circ. Res
, vol.101
, pp. 893-901
-
-
True, A.L.1
Olive, M.2
Boehm, M.3
San, H.4
Westrick, R.J.5
Raghavachari, N.6
-
176
-
-
66049098514
-
Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-β production
-
Tzima, S., Victoratos, P., Kranidioti, K., Alexiou, M., and Kollias, G. (2009). Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-β production. J. Exp. Med. 206, 1167-1179. doi: 10.1084/jem.20081582
-
(2009)
J. Exp. Med
, vol.206
, pp. 1167-1179
-
-
Tzima, S.1
Victoratos, P.2
Kranidioti, K.3
Alexiou, M.4
Kollias, G.5
-
177
-
-
84987657125
-
Hepatic overexpression of hemopexin inhibits inflammation and vascular stasis in murine models of sickle cell disease
-
Vercellotti, G. M., Zhang, P., Nguyen, J., Abdulla, F., Chen, C., Nguyen, P., et al. (2016). Hepatic overexpression of hemopexin inhibits inflammation and vascular stasis in murine models of sickle cell disease. Mol. Med. 22, 437-451. doi: 10.2119/molmed.2016.00063
-
(2016)
Mol. Med
, vol.22
, pp. 437-451
-
-
Vercellotti, G.M.1
Zhang, P.2
Nguyen, J.3
Abdulla, F.4
Chen, C.5
Nguyen, P.6
-
178
-
-
0024574001
-
Oxidative effects of heme and porphyrins on proteins and lipids
-
Vincent, S. H. (1989). Oxidative effects of heme and porphyrins on proteins and lipids. Semin. Hematol. 26, 105-113
-
(1989)
Semin. Hematol
, vol.26
, pp. 105-113
-
-
Vincent, S.H.1
-
179
-
-
0023759940
-
The influence of heme-binding proteins in heme-catalyzed oxidations
-
Vincent, S. H., Grady, R. W., Shaklai, N., Snider, J. M., and Muller-Eberhard, U. (1988). The influence of heme-binding proteins in heme-catalyzed oxidations. Arch. Biochem. Biophys. 265, 539-550. doi: 10.1016/0003-9861(88)90159-2
-
(1988)
Arch. Biochem. Biophys
, vol.265
, pp. 539-550
-
-
Vincent, S.H.1
Grady, R.W.2
Shaklai, N.3
Snider, J.M.4
Muller-Eberhard, U.5
-
180
-
-
0022401009
-
A protein of the Z class of liver cytosolic proteins in the rat that preferentially binds heme
-
Vincent, S. H., and Muller Eberhard, U. (1985). A protein of the Z class of liver cytosolic proteins in the rat that preferentially binds heme. J. Biol. Chem. 260, 14521-14528
-
(1985)
J. Biol. Chem
, vol.260
, pp. 14521-14528
-
-
Vincent, S.H.1
Muller Eberhard, U.2
-
181
-
-
84875475916
-
Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases
-
Vinchi, F., De Franceschi, L., Ghigo, A., Townes, T., Cimino, J., Silengo, L., et al. (2013). Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases. Circulation 127, 1317-1329. doi: 10.1161/CIRCULATIONAHA.112.130179
-
(2013)
Circulation
, vol.127
, pp. 1317-1329
-
-
Vinchi, F.1
De Franceschi, L.2
Ghigo, A.3
Townes, T.4
Cimino, J.5
Silengo, L.6
-
182
-
-
46749135674
-
Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload
-
Vinchi, F., Gastaldi, S., Silengo, L., Altruda, F., and Tolosano, E. (2008). Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload. Am. J. Pathol. 173, 289-299. doi: 10.2353/ajpath.2008.071130
-
(2008)
Am. J. Pathol
, vol.173
, pp. 289-299
-
-
Vinchi, F.1
Gastaldi, S.2
Silengo, L.3
Altruda, F.4
Tolosano, E.5
-
183
-
-
84958078769
-
Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease
-
Vinchi, F., Costa da Silva, M., Ingoglia, G., Petrillo, S., Brinkman, N., Zuercher, A., et al. (2016). Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease. Blood 127, 473-486. doi: 10.1182/blood-2015-08-663245
-
(2016)
Blood
, vol.127
, pp. 473-486
-
-
Vinchi, F.1
Costa da Silva, M.2
Ingoglia, G.3
Petrillo, S.4
Brinkman, N.5
Zuercher, A.6
-
184
-
-
0030734872
-
Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells
-
Wagener, E., Feldman, T., de Witte, T., and Abraham, N. G. (1997). Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells. Proc. Soc. Exp. Biol. Med. 216, 456-463. doi: 10.3181/00379727-216-44197
-
(1997)
Proc. Soc. Exp. Biol. Med
, vol.216
, pp. 456-463
-
-
Wagener, E.1
Feldman, T.2
de Witte, T.3
Abraham, N.G.4
-
185
-
-
0035885926
-
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase
-
Wagener, F. A., Eggert, A., Boerman, O. C., Oyen, W. J., Verhofstad, A., Abraham, N. G., et al. (2001). Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood 98, 1802-1811. doi: 10.1182/blood.V98.6.1802
-
(2001)
Blood
, vol.98
, pp. 1802-1811
-
-
Wagener, F.A.1
Eggert, A.2
Boerman, O.C.3
Oyen, W.J.4
Verhofstad, A.5
Abraham, N.G.6
-
186
-
-
0041967387
-
Different faces of the heme-heme oxygenase system in inflammation
-
Wagener, F. A., Volk, H. D., Willis, D., Abraham, N. G., Soares, M. P., Adema, G. J., et al. (2003). Different faces of the heme-heme oxygenase system in inflammation. Pharmacol. Rev. 55, 551-571. doi: 10.1124/pr.55.3.5
-
(2003)
Pharmacol. Rev
, vol.55
, pp. 551-571
-
-
Wagener, F.A.1
Volk, H.D.2
Willis, D.3
Abraham, N.G.4
Soares, M.P.5
Adema, G.J.6
-
187
-
-
84904466361
-
Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia
-
Wang, D., Cortes-Puch, I., Sun, J., Solomon, S. B., Kanias, T., Remy, K. E., et al. (2012a). Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia. Transfusion 54, 1712-1724. doi: 10.1111/trf.12607
-
(2012)
Transfusion
, vol.54
, pp. 1712-1724
-
-
Wang, D.1
Cortes-Puch, I.2
Sun, J.3
Solomon, S.B.4
Kanias, T.5
Remy, K.E.6
-
188
-
-
84861782317
-
Transfusion of older stored blood and risk of death: a meta-analysis
-
Wang, D., Sun, J., Solomon, S. B., Klein, H. G., and Natanson, C. (2012b). Transfusion of older stored blood and risk of death: a meta-analysis. Transfusion 52, 1184-1195. doi: 10.1111/j.1537-2995.2011.03466.x
-
(2012)
Transfusion
, vol.52
, pp. 1184-1195
-
-
Wang, D.1
Sun, J.2
Solomon, S.B.3
Klein, H.G.4
Natanson, C.5
-
189
-
-
84921934463
-
Mice are not men
-
Warren, H. S., Tompkins, R. G., Moldawer, L. L., Seok, J., Xu, W., Mindrinos, M. N., et al. (2015). Mice are not men. Proc. Natl. Acad. Sci. U.S.A. 112:E345. doi: 10.1073/pnas.1414857111
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
-
-
Warren, H.S.1
Tompkins, R.G.2
Moldawer, L.L.3
Seok, J.4
Xu, W.5
Mindrinos, M.N.6
-
190
-
-
79960054643
-
Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury
-
Wei, Q., Hill, W. D., Su, Y., Huang, S., and Dong, Z. (2011). Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury. Am. J. Physiol. Renal Physiol. 301, F162-F170. doi: 10.1152/ajprenal.00438.2010
-
(2011)
Am. J. Physiol. Renal Physiol
, vol.301
, pp. F162-F170
-
-
Wei, Q.1
Hill, W.D.2
Su, Y.3
Huang, S.4
Dong, Z.5
-
191
-
-
1842431892
-
Biology of heme in health and disease
-
Wijayanti, N., Katz, N., and Immenschuh, S. (2004). Biology of heme in health and disease. Curr. Med. Chem. 11, 981-986. doi: 10.2174/0929867043455521
-
(2004)
Curr. Med. Chem
, vol.11
, pp. 981-986
-
-
Wijayanti, N.1
Katz, N.2
Immenschuh, S.3
-
192
-
-
20444459893
-
Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes
-
Wijayanti, N., Kietzmann, T., and Immenschuh, S. (2005). Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes. J. Biol. Chem. 280, 21820-21829. doi: 10.1074/jbc.M502943200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21820-21829
-
-
Wijayanti, N.1
Kietzmann, T.2
Immenschuh, S.3
-
193
-
-
0032893958
-
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
-
Yachie, A., Niida, Y., Wada, T., Igarashi, N., Kaneda, H., Toma, T., et al. (1999). Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J. Clin. Invest. 103, 129-135. doi: 10.1172/JCI4165
-
(1999)
J. Clin. Invest
, vol.103
, pp. 129-135
-
-
Yachie, A.1
Niida, Y.2
Wada, T.3
Igarashi, N.4
Kaneda, H.5
Toma, T.6
-
194
-
-
0033925281
-
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema
-
Yamada, N., Yamaya, M., Okinaga, S., Nakayama, K., Sekizawa, K., Shibahara, S., et al. (2000). Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am. J. Hum. Genet. 66, 187-195. doi: 10.1086/302729
-
(2000)
Am. J. Hum. Genet
, vol.66
, pp. 187-195
-
-
Yamada, N.1
Yamaya, M.2
Okinaga, S.3
Nakayama, K.4
Sekizawa, K.5
Shibahara, S.6
-
195
-
-
84984695672
-
Regulation of intracellular heme trafficking revealed by subcellular reporters
-
Yuan, X., Rietzschel, N., Kwon, H., Walter Nuno, A. B., Hanna, D. A., Phillips, J. D., et al. (2016). Regulation of intracellular heme trafficking revealed by subcellular reporters. Proc. Natl. Acad. Sci. U.S.A. 113, E5144-E5152. doi: 10.1073/pnas.1609865113
-
(2016)
Proc. Natl. Acad. Sci. U.S.A
, vol.113
, pp. E5144-E5152
-
-
Yuan, X.1
Rietzschel, N.2
Kwon, H.3
Walter Nuno, A.B.4
Hanna, D.A.5
Phillips, J.D.6
-
196
-
-
84885045002
-
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury
-
Zarjou, A., Bolisetty, S., Joseph, R., Traylor, A., Apostolov, E. O., Arosio, P., et al. (2013). Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J. Clin. Invest. 123, 4423-4434. doi: 10.1172/JCI67867
-
(2013)
J. Clin. Invest
, vol.123
, pp. 4423-4434
-
-
Zarjou, A.1
Bolisetty, S.2
Joseph, R.3
Traylor, A.4
Apostolov, E.O.5
Arosio, P.6
-
197
-
-
84903637752
-
Hemin controls T cell polarization in sickle cell alloimmunization
-
Zhong, H., Bao, W., Friedman, D., and Yazdanbakhsh, K. (2014). Hemin controls T cell polarization in sickle cell alloimmunization. J. Immunol. 193, 102-110. doi: 10.4049/jimmunol.1400105
-
(2014)
J. Immunol
, vol.193
, pp. 102-110
-
-
Zhong, H.1
Bao, W.2
Friedman, D.3
Yazdanbakhsh, K.4
|