Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis

Clinical and Experimental Immunology

Volumn 140, Issue 3, 2005, Pages 547-555

  Paul, G ^a   Bataille, F ^a   Obermeier, F ^a   Bock, J ^a   Klebl, F ^a   Strauch, U ^a   Lochbaum, D ^a   Rummele P ^a   Farkas, S ^a   Scholmerich J ^a   Fleck, M ^a   Rogler, G ^a   Herfarth, Hans ^a,b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Apoptosis; Crohn's disease; HO 1; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

CASPASE 3; CYTOKINE; DEXTRAN; GAMMA INTERFERON; HEME OXYGENASE 1; INTERLEUKIN 10; PORPHYRIN COBALT; PROTOPORPHYRIN; SODIUM SULFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; COLITIS; COLON CARCINOMA; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; ENZYME ACTIVITY; EXPERIMENTAL MODEL; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCORING SYSTEM; ULCERATIVE COLITIS;

ACUTE DISEASE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CHRONIC DISEASE; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; DOWN-REGULATION; FEMALE; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; PROTOPORPHYRINS; UP-REGULATION;

EID: 20444472459     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02775.x     Document Type: Article

References (54)

1. Fiocchi C. Inflammatory bowel disease. Etiol Pathogen Gastroenterol 1998; 115:182-205.
2. Simmonds NJ, Allen RE, Stevens TR, Van Someren RN, Blake DR, Rampton DS. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease. Gastroenterology 1992; 103:186-96.
3. Oberle S, Schwartz P, Abate A, Schroder H. The antioxidant defense protein ferritin is a novel and specific target for pentaerithrityl tetranitrate in endothelial cells. Biochem Biophys Res Commun 1999; 261:28-34.
4. Yesilkaya A, Altinayak R, Korgun DK. The antioxidant effect of free bilirubin on cumene-hydroperoxide treated human leukocytes. General Pharmacol 2000; 35:17-20.
5. Choi AM, Otterbein LE. Emerging role of carbon monoxide in physiologic and pathophysiologic states. Antioxid Redox Signal 2002; 4:227-8.
6. Hancock WW, Buelow R, Sayegh MH, Turka LA. Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes. Nat Med 1998; 4:1392-6.
7. Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, Choi AM. Exogenous administration of haem oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 1999; 103:1047-54.
8. Otterbein LE, Lee PJ, Chin BY et al. Protective effects of haem oxygenase-1 in acute lung injury. Chest 1999; 116:561-3.
9. Soares MP, Lin Y, Anrather J et al. Expression of haem oxygenase-1 can determine cardiac xenograft survival. Nat Med 1998; 4:1073-7.
10. Poss KD, Tonegawa S. Reduced stress defense in haem oxygenase 1-deficient cells. Proc Natl Acad Sci USA 1997; 94:10925-30.
11. Poss KD, Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA 1997; 94:10919-24.
12. Wang LJ, Lee TS, Lee FY, Pai RC, Chau LY. Expression of haem oxygenase-1 in atherosclerotic lesions. Am J Pathol 1998; 152:711-20.
13. Ishikawa K, Navab M, Leitinger N, Fogelman AM, Lusis AJ. Induction of haem oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J Clin Invest 1997; 100:1209-16.
14. Otterbein LE, Mantell LL, Choi AM. Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 1999; 276:L688-94.
15. Yet SF, Pellacani A, Patterson C et al. Induction of haem oxygenase-1 expression in vascular smooth muscle cells. A link to endotoxic shock. J Biol Chem 1997; 272:4295-301.
16. Horvath I, Loukides S, Wodehouse T, Kharitonov SA, Cole PJ, Barnes PJ. Increased levels of exhaled carbon monoxide in bronchiectasis: a new marker of oxidative stress. Thorax 1998; 53:867-70.
17. Sato H, Siow RC, Bartlett S et al. Expression of stress proteins haem oxygenase-1 and -2 in acute pancreatitis and pancreatic islet betaTC3 and acinar AR42J cells. FEBS Lett 1997; 405:219-23.
18. Akamatsu Y, Haga M, Tyagi S et al. Heme oxygenase-1-derived carbon monoxide protects hearts from transplant-associated ischemia reperfusion injury. FASEB J 2004; 18:771-2.
19. Zhang X, Shan P, Jiang D et al. Small interfering RNA targeting haem oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J Biol Chem 2004; 279:10677-84.
20. Wang WP, Guo X, Koo MW et al. Protective role of haem oxygenase-1 on trinitrobenzene sulfonic acid-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol 2001; 281:G586-94.
21. Tanaka M, Riddell RH, Saito H, Soma Y, Hidaka H, Kudo H. Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis. Scand J Gastroenterol 1999; 34:55-67.
22. Gerbitz A, Ewing P, Wilke A et al. Induction of haem oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation. Biol Blood Marrow Transplant 2004; 10:461-72.
23. Obermeier F, Dunger N, Strauch UG et al. Contrasting activity of cytosin-guanosin dinucleotide oligonucleotides in mice with experimental colitis. Clin Exp Immunol 2003; 134:217-24.
24. Kojouharoff G, Hans W, Obermeier F et al. Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol 1997; 107:353-8.
25. Herfarth H, Brand K, Rath HC, Rogler G, Scholmerich J, Falk W. Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin. Clin Exp Immunol 2000; 120:59-65.
26. Abreu MT, Palladino AA, Arnold ET, Kwon RS, McRoberts JA. Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells. Gastroenterology 2000; 119:1524-36.
27. Dignass AU, Baumgart DC, Sturm A. Review article: the aetiopathogenesis of inflammatory bowel disease - immunology and repair mechanisms. Aliment Pharmacol Ther 2004; 20:9-17.
28. Farkas S, Herfarth H, Rossle M et al. Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice. Clin Exp Immunol 2001; 126:250-8.
29. Obermeier F, Dunger N, Deml L, Herfarth H, Scholmerich J, Falk W. CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice. Eur J Immunol 2002; 32:2084-92.
30. Naito Y, Takagi T, Yoshikawa T. Heme oxygenase-1: a new therapeutic target for inflammatory bowel disease. Aliment Pharmacol Ther 2004; 20:177-84.
31. Krieglstein CF, Cerwinka WH, Laroux FS et al. Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide. J Exp Med 2001; 194:1207-18.
32. Obermeier F, Kojouharoff G, Hans W, Scholmerich J, Gross V, Falk W. Interferon-gamma (IFN-gamma) - and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol 1999; 116:238-45.
33. Araki Y, Andoh A, Fujiyama Y. The free radical scavenger edaravone suppresses experimental dextran sulfate sodium-induced colitis in rats. Int J Mol Med 2003; 12:125-9.
34. Hans W, Scholmerich J, Gross V, Falk W. Interleukin-12 induced interferon-gamma increases inflammation in acute dextran sulfate sodium induced colitis in mice. Eur Cytokine Netw 2000; 11:67-74.
35. Carrier J, Aghdassi E, Platt I, Cullen J, Allard JP. Effect of oral iron supplementation on oxidative stress and colonic inflammation in rats with induced colitis. Aliment Pharmacol Ther 2001; 15:1989-99.
36. Kruidenier L, van Meeteren ME, Kuiper I et al. Attenuated mild colonic inflammation and improved survival from severe DSS-colitis of transgenic Cu/Zn-SOD mice. Free Radic Biol Med 2003; 34:753-65.
37. Vetuschi A, Latella G, Sferra R, Caprilli R, Gaudio E. Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci 2002; 47:1447-57.
38. Tenhunen R, Marver HS, Schmid R. The enzymatic conversion of haem to bilirubin by microsomal haem oxygenase. Proc Natl Acad Sci USA 1968; 61:748-55.
39. Eisenstein RS, Munro HN. Translational regulation of ferritin synthesis by iron. Enzyme 1990; 44:42-58.
40. Eisenstein RS, Garcia-Mayol D, Pettingell W, Munro HN. Regulation of ferritin and haem oxygenase synthesis in rat fibroblasts by different forms of iron. Proc Natl Acad Sci USA 1991; 88:688-92.
41. Soares MP, Seldon MP, Gregoire IP et al. Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J Immunol 2004; 172:3553-63.
42. Wagener FA, da Silva JL, Farley T, de Witte T, Kappas A, Abraham NG. Differential effects of haem oxygenase isoforms on haem mediation of endothelial intracellular adhesion molecule 1 expression. J Pharmacol Exp Ther 1999; 291:416-23.
43. Tanaka S, Akaike T, Fang J et al. Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour. Br J Cancer 2003; 88:902-9.
44. Tobiasch E, Gunther L, Bach FH. Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli. J Invest Med 2001; 49:566-71.
45. Ozawa N, Goda N, Makino N, Yamaguchi T, Yoshimura Y, Suematsu M. Leydig cell-derived haem oxygenase-1 regulates apoptosis of premeiotic germ cells in response to stress. J Clin Invest 2002; 109:457-67.
46. Sato K, Balla J, Otterbein L et al. Carbon monoxide generated by haem oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol 2001; 166:4185-94.
47. Brouard S, Otterbein LE, Anrather J et al. Carbon monoxide generated by haem oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med 2000; 192:1015-26.
48. Berberat PO, Katori M, Kaczmarek E et al. Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. FASEB J 2003; 17:1724-6.
49. Kato H, Amersi F, Buelow R et al. Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation. Am J Transplant 2001; 1:121-8.
50. Attuwaybi BO, Kozar RA, Moore-Olufemi SD et al. Heme oxygenase-1 induction by hemin protects against gut ischemia/ reperfusion injury. J Surg Res 2004; 118:53-7.
51. Hans W, Scholmerich J, Gross V, Falk W. The role of the resident intestinal flora in acute and chronic dextran sulfate sodium-induced colitis in mice. Eur J Gastroenterol Hepatol 2000; 12:267-73.
52. Pileggi A, Cattan P, Berney T et al. HO-1 upregulation protects the pancreatic cell line betaTC3 from cytokines and Fas-induced apoptosis. Transplant Proc 2001; 33:266-7.
53. Pileggi A, Molano RD, Berney T et al. Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. Diabetes 2001; 50:1983-91.
54. Katori M, Buelow R, Ke B et al. Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway. Transplantation 2002; 73:287-92.