Heme impairs prostaglandin E2 and TGF-β production by human mononuclear cells via Cu/Zn superoxide dismutase: Insight into the pathogenesis of severe malaria

Journal of Immunology

Volumn 185, Issue 2, 2010, Pages 1196-1204

  Andrade, Bruno B ^a,b,h   Araújo Santos, Théo ^a,b   Luz, Nívea F ^a,b   Khouri, Ricardo ^g   Bozza, Marcelo T ^f   Camargo, Luís M A ^c,e   Barral, Aldina ^a,b,d   Borges, Valéria M ^a,d   Barral Netto, Manoel ^a,b,d  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Instituto Nacional de Ciencia e Tecnologia   (Brazil)

^e Faculdade de Medicina   (Portugal)

^f FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^g REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^h NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; CD14 ANTIGEN; COPPER ZINC SUPEROXIDE DISMUTASE; HEME; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA; SUPEROXIDE DISMUTASE;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEMOLYSIS; HUMAN; HUMAN CELL; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PATHOGENESIS; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; BLOOD; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PARASITOLOGY; PHYSIOLOGY; RNA INTERFERENCE;

ADOLESCENT; ADULT; ANTIGENS, CD14; CELLS, CULTURED; DINOPROSTONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; HEME; HEMOLYSIS; HUMANS; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; MALARIA, VIVAX; MALE; MIDDLE AGED; PLASMODIUM VIVAX; RNA INTERFERENCE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; YOUNG ADULT;

EID: 77955507567     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0904179     Document Type: Article

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