Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

Blood

Volumn 123, Issue 24, 2014, Pages 3818-3827

  Chen, Grace ^a   Zhang, Dachuan ^a   Fuchs, Tobias A ^b,c   Manwani, Deepa ^a   Wagner, Denisa D ^b,c   Frenette, Paul S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; HEME OXYGENASE 1; HEMIN; HEMOPEXIN; PROTOPORPHYRIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CAUSE OF DEATH; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HEMOLYSIS; HUMAN; HYPOTHERMIA; IMMUNOPATHOGENESIS; LUNG ALVEOLUS WALL; LUNG BLOOD VESSEL; LUNG HOMOGENATE; LUNG MICROCIRCULATION; MICROCIRCULATION; MOLECULAR WEIGHT; MOUSE; NEUTROPHIL; NEUTROPHIL EXTRACELLULAR TRAP; NONHUMAN; PLASMA FACTOR; PRIORITY JOURNAL; SICKLE CELL ANEMIA; SYSTEMIC CIRCULATION;

ADULT; ANEMIA, SICKLE CELL; ANIMALS; DISEASE MODELS, ANIMAL; EXTRACELLULAR SPACE; HEME; HUMANS; LUNG; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROCIRCULATION; NEUTROPHIL ACTIVATION; NEUTROPHILS;

EID: 84902585238     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-10-529982     Document Type: Article

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