Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 7, 2011, Pages 922-931

  Spiller, Fernando ^a   Costa, Carlotta ^b   Souto, Fabrício O ^a   Vinchi, Francesca ^b   Mestriner, Fabíola L A C ^a   Laure, Helen J ^a,c   Alves Filho, José C ^a   Freitas, Andressa ^a   Rosa, José C ^a,c   Ferreira, Sérgio H ^a   Altruda, Fiorella ^b   Hirsch, Emilio ^b   Greene, Lewis J ^a,c   Tolosano, Emanuela ^b   Cunha, Fernando Q ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF TURIN   (Italy)

^c Hemocenter Foundation of Ribeirão Preto   (Brazil)

Author keywords

Cecal ligation and puncture; Hemopexin; Neutrophil migration; Sepsis; Survival

Indexed keywords

ADENOSINE TRIPHOSPHATE; CD11B ANTIGEN; CHEMOKINE RECEPTOR CXCR2; COMPLEMENT COMPONENT C5A; HEMOPEXIN; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DISEASE SEVERITY; IN VITRO STUDY; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPSIS; SURVIVAL RATE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; CELL MOVEMENT; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ESCHERICHIA COLI; HEMOPEXIN; L-SELECTIN; MASS SPECTROMETRY; MICE; MICE, INBRED STRAINS; NEUTROPHILS; RANDOM ALLOCATION; RECEPTORS, INTERLEUKIN-8B; SEPSIS; SURVIVAL RATE; THIOGLYCOLATES; UP-REGULATION;

EID: 79953320619     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201002-0223OC     Document Type: Article

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