-
1
-
-
56749164791
-
Nutrient sensing and inflammation in metabolic diseases
-
Hotamisligil GS, Erbay E. Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol 2008;8:923-934.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 923-934
-
-
Hotamisligil, G.S.1
Erbay, E.2
-
2
-
-
84886251068
-
An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy
-
Palomer X, Salvado L, Barroso E, Vazquez-Carrera M. An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy. Int J Cardiol 2013;168:3160-3172.
-
(2013)
Int J Cardiol
, vol.168
, pp. 3160-3172
-
-
Palomer, X.1
Salvado, L.2
Barroso, E.3
Vazquez-Carrera, M.4
-
3
-
-
84897536939
-
Activation of Toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation
-
Fuentes-Antras J, Ioan AM, Tunon J, Egido J, Lorenzo O. Activation of Toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation. Int J Endocrinol 2014;2014:847827.
-
(2014)
Int J Endocrinol
, vol.2014
, pp. 847827
-
-
Fuentes-Antras, J.1
Ioan, A.M.2
Tunon, J.3
Egido, J.4
Lorenzo, O.5
-
4
-
-
85014373529
-
Adipose tissue inflammation: A cause or consequence of obesity-related insulin resistance
-
Bluher M. Adipose tissue inflammation: A cause or consequence of obesity-related insulin resistance Clin Sci 2016;130:1603-1614.
-
(2016)
Clin Sci
, vol.130
, pp. 1603-1614
-
-
Bluher, M.1
-
5
-
-
84875226936
-
Molecular and metabolic mechanisms of cardiac dysfunction in diabetes
-
Mandavia CH, Aroor AR, Demarco VG, Sowers J.R. Molecular and metabolic mechanisms of cardiac dysfunction in diabetes. Life Sci 2013;92:601-608.
-
(2013)
Life Sci
, vol.92
, pp. 601-608
-
-
Mandavia, C.H.1
Aroor, A.R.2
Demarco, V.G.3
Sowers, J.R.4
-
6
-
-
84870494737
-
Macrophages modulate cardiac function in lipotoxic cardiomyopathy
-
Schilling JD, Machkovech HM, Kim AH, Schwendener R, Schaffer JE. Macrophages modulate cardiac function in lipotoxic cardiomyopathy. Am J Physiol Heart Circ Physiol 2012;303:H1366-H1373.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
, pp. H1366-H1373
-
-
Schilling, J.D.1
MacHkovech, H.M.2
Kim, A.H.3
Schwendener, R.4
Schaffer, J.E.5
-
7
-
-
84958124870
-
Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
-
Jia G, DeMarco VG, Sowers J.R. Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy. Nat Rev Endocrinol 2016;12:144-153.
-
(2016)
Nat Rev Endocrinol
, vol.12
, pp. 144-153
-
-
Jia, G.1
DeMarco, V.G.2
Sowers, J.R.3
-
8
-
-
84886234690
-
Translation of hemodynamic stress to sterile inflammation in the heart
-
Nakayama H, Otsu K. Translation of hemodynamic stress to sterile inflammation in the heart. Trends Endocrinol Metab 2013;24:546-553.
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 546-553
-
-
Nakayama, H.1
Otsu, K.2
-
9
-
-
84923046255
-
Cholesterol, inflammation and innate immunity
-
Tall AR, Yvan-Charvet L. Cholesterol, inflammation and innate immunity. Nat Rev Immunol 2015;15:104-116.
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 104-116
-
-
Tall, A.R.1
Yvan-Charvet, L.2
-
10
-
-
74549178528
-
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
-
Arslan F, Smeets MB, O'Neill LA, Keogh B, McGuirk P, Timmers L, Tersteeg C, Hoefer IE, Doevendans PA, Pasterkamp G, de Kleijn DP. Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody. Circulation 2010;121:80-90.
-
(2010)
Circulation
, vol.121
, pp. 80-90
-
-
Arslan, F.1
Smeets, M.B.2
O'Neill, L.A.3
Keogh, B.4
McGuirk, P.5
Timmers, L.6
Tersteeg, C.7
Hoefer, I.E.8
Doevendans, P.A.9
Pasterkamp, G.10
De Kleijn, D.P.11
-
11
-
-
34247363161
-
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction
-
Favre J, Musette P, Douin-Echinard V, Laude K, Henry JP, Arnal JF, Thuillez C, Richard V. Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol 2007;27:1064-1071.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1064-1071
-
-
Favre, J.1
Musette, P.2
Douin-Echinard, V.3
Laude, K.4
Henry, J.P.5
Arnal, J.F.6
Thuillez, C.7
Richard, V.8
-
12
-
-
84860789456
-
Treatment with OPN-305, a humanized anti-toll-like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs
-
Arslan F, Houtgraaf JH, Keogh B, Kazemi K, de Jong R, McCormack WJ, O'Neill LA, McGuirk P, Timmers L, Smeets MB, Akeroyd L, Reilly M, Pasterkamp G, de Kleijn DP. Treatment with OPN-305, a humanized anti-toll-like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs. Circ Cardiovasc Interv 2012;5:279-287.
-
(2012)
Circ Cardiovasc Interv
, vol.5
, pp. 279-287
-
-
Arslan, F.1
Houtgraaf, J.H.2
Keogh, B.3
Kazemi, K.4
De Jong, R.5
McCormack, W.J.6
O'Neill, L.A.7
McGuirk, P.8
Timmers, L.9
Smeets, M.B.10
Akeroyd, L.11
Reilly, M.12
Pasterkamp, G.13
De Kleijn, D.P.14
-
13
-
-
84895536008
-
Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1beta upregulation via nuclear factor kappaB activation
-
Higashikuni Y, Tanaka K, Kato M, Nureki O, Hirata Y, Nagai R, Komuro I, Sata M. Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1beta upregulation via nuclear factor kappaB activation. J Am Heart Assoc 2013;2:e000267.
-
(2013)
J Am Heart Assoc
, vol.2
, pp. e000267
-
-
Higashikuni, Y.1
Tanaka, K.2
Kato, M.3
Nureki, O.4
Hirata, Y.5
Nagai, R.6
Komuro, I.7
Sata, M.8
-
14
-
-
84894593288
-
Inhibition of Tolllike receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation
-
Wang L, Li YL, Zhang CC, Cui W, Wang X, Xia Y, Du J, Li HH. Inhibition of Tolllike receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation. Cardiovasc Res 2014;101:383-392.
-
(2014)
Cardiovasc Res
, vol.101
, pp. 383-392
-
-
Wang, L.1
Li, Y.L.2
Zhang, C.C.3
Cui, W.4
Wang, X.5
Xia, Y.6
Du, J.7
Li, H.H.8
-
15
-
-
8144229686
-
Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice
-
Nozaki N, Shishido T, Takeishi Y, Kubota I. Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice. Circulation 2004;110:2869-2874.
-
(2004)
Circulation
, vol.110
, pp. 2869-2874
-
-
Nozaki, N.1
Shishido, T.2
Takeishi, Y.3
Kubota, I.4
-
16
-
-
1242336786
-
Reduced myocardial ischemia-reperfusion injury in Toll-like receptor 4-deficient mice
-
Oyama J, Blais C, Jr, Liu X, Pu M, Kobzik L, Kelly RA, Bourcier T. Reduced myocardial ischemia-reperfusion injury in Toll-like receptor 4-deficient mice. Circulation 2004;109:784-789.
-
(2004)
Circulation
, vol.109
, pp. 784-789
-
-
Oyama, J.1
Blais, C.2
Liu, X.3
Pu, M.4
Kobzik, L.5
Kelly, R.A.6
Bourcier, T.7
-
17
-
-
41149165830
-
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
-
Timmers L, Sluijter JPG, van Keulen JK, Hoefer IE, Nederhoff MGJ, Goumans MJ, Doevendans PA, van Echteld CJA, Joles JA, Quax PH, Piek JJ, Pasterkamp G, de Kleijn DPV. Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res 2008;102:257-264.
-
(2008)
Circ Res
, vol.102
, pp. 257-264
-
-
Timmers, L.1
Sluijter, J.P.G.2
Van Keulen, J.K.3
Hoefer, I.E.4
Nederhoff, M.G.J.5
Goumans, M.J.6
Doevendans, P.A.7
Van Echteld, C.J.A.8
Joles, J.A.9
Quax, P.H.10
Piek, J.J.11
Pasterkamp, G.12
De Kleijn, D.P.V.13
-
18
-
-
84860705893
-
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
-
Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, Oyabu J, Murakawa T, Nakayama H, Nishida K, Akira S, Yamamoto A, Komuro I, Otsu K. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature 2012;485:251-255.
-
(2012)
Nature
, vol.485
, pp. 251-255
-
-
Oka, T.1
Hikoso, S.2
Yamaguchi, O.3
Taneike, M.4
Takeda, T.5
Tamai, T.6
Oyabu, J.7
Murakawa, T.8
Nakayama, H.9
Nishida, K.10
Akira, S.11
Yamamoto, A.12
Komuro, I.13
Otsu, K.14
-
19
-
-
74549184092
-
The NLRP3 inflammasome: A sensor for metabolic danger
-
Schroder K, Zhou R, Tschopp J. The NLRP3 inflammasome: A sensor for metabolic danger Science 2010;327:296-300.
-
(2010)
Science
, vol.327
, pp. 296-300
-
-
Schroder, K.1
Zhou, R.2
Tschopp, J.3
-
20
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 2011;17:179-188.
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
21
-
-
33947714585
-
A role for caspase-1 in heart failure
-
Merkle S, Frantz S, Schon MP, Bauersachs J, Buitrago M, Frost RJ, Schmitteckert EM, Lohse MJ, Engelhardt S. A role for caspase-1 in heart failure. Circ Res 2007;100:645-653.
-
(2007)
Circ Res
, vol.100
, pp. 645-653
-
-
Merkle, S.1
Frantz, S.2
Schon, M.P.3
Bauersachs, J.4
Buitrago, M.5
Frost, R.J.6
Schmitteckert, E.M.7
Lohse, M.J.8
Engelhardt, S.9
-
22
-
-
84872696318
-
The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1beta
-
Bracey NA, Beck PL, Muruve DA, Hirota SA, Guo J, Jabagi H, Wright JR, Jr., Macdonald JA, Lees-Miller JP, Roach D, Semeniuk LM, Duff HJ. The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1beta. Exp Physiol 2013;98:462-472.
-
(2013)
Exp Physiol
, vol.98
, pp. 462-472
-
-
Bracey, N.A.1
Beck, P.L.2
Muruve, D.A.3
Hirota, S.A.4
Guo, J.5
Jabagi, H.6
Wright, J.R.7
MacDonald, J.A.8
Lees-Miller, J.P.9
Roach, D.10
Semeniuk, L.M.11
Duff, H.J.12
-
23
-
-
84883562084
-
Cardiac metabolism in heart failure: Implications beyond ATP production
-
Doenst T, Nguyen TD, Abel ED. Cardiac metabolism in heart failure: Implications beyond ATP production. Circ Res 2013;113:709-724.
-
(2013)
Circ Res
, vol.113
, pp. 709-724
-
-
Doenst, T.1
Nguyen, T.D.2
Abel, E.D.3
-
24
-
-
50549202600
-
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963;1:785-789.
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
26
-
-
0032881635
-
Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
-
Russell RR III, Bergeron R, Shulman GI, Young LH. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am J Physiol 1999;277:H643-649.
-
(1999)
Am J Physiol
, vol.277
, pp. H643-649
-
-
Russell, R.R.1
Bergeron, R.2
Shulman, G.I.3
Young, L.H.4
-
27
-
-
33947239659
-
The failing heart-an engine out of fuel
-
Neubauer S. The failing heart-an engine out of fuel. N Engl J Med 2007;356:1140-1151.
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
28
-
-
84872567025
-
Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction
-
Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F. Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 2013;15:150-157.
-
(2013)
Eur J Heart Fail
, vol.15
, pp. 150-157
-
-
Stride, N.1
Larsen, S.2
Hey-Mogensen, M.3
Sander, K.4
Lund, J.T.5
Gustafsson, F.6
Kober, L.7
Dela, F.8
-
29
-
-
0037010011
-
Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, failing human myocardium measured noninvasively with(31)P-SLOOP magnetic resonance spectroscopy
-
Beer M, Seyfarth T, Sandstede J, Landschutz W, Lipke C, Kostler H, von Kienlin M, Harre K, Hahn D, Neubauer S. Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy. J Am Coll Cardiol 2002;40:1267-1274.
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 1267-1274
-
-
Beer, M.1
Seyfarth, T.2
Sandstede, J.3
Landschutz, W.4
Lipke, C.5
Kostler, H.6
Von Kienlin, M.7
Harre, K.8
Hahn, D.9
Neubauer, S.10
-
30
-
-
85007297398
-
Insulin signaling and heart failure
-
Riehle C, Abel ED. Insulin signaling and heart failure. Circ Res 2016;118:1151-1169.
-
(2016)
Circ Res
, vol.118
, pp. 1151-1169
-
-
Riehle, C.1
Abel, E.D.2
-
31
-
-
84864657351
-
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipidinduced insulin resistance
-
Pal D, Dasgupta S, Kundu R, Maitra S, Das G, Mukhopadhyay S, Ray S, Majumdar SS, Bhattacharya S. Fetuin-A acts as an endogenous ligand of TLR4 to promote lipidinduced insulin resistance. Nat Med 2012;18:1279-1285.
-
(2012)
Nat Med
, vol.18
, pp. 1279-1285
-
-
Pal, D.1
Dasgupta, S.2
Kundu, R.3
Maitra, S.4
Das, G.5
Mukhopadhyay, S.6
Ray, S.7
Majumdar, S.S.8
Bhattacharya, S.9
-
32
-
-
84884545858
-
Activation and regulation of the pattern recognition receptors in obesity-induced adipose tissue inflammation and insulin resistance
-
Watanabe Y, Nagai Y, Takatsu K. Activation and regulation of the pattern recognition receptors in obesity-induced adipose tissue inflammation and insulin resistance. Nutrients 2013;5:3757-3778.
-
(2013)
Nutrients
, vol.5
, pp. 3757-3778
-
-
Watanabe, Y.1
Nagai, Y.2
Takatsu, K.3
-
33
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. A central role for JNK in obesity and insulin resistance. Nature 2002;420:333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
35
-
-
2442492971
-
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
-
Peterson LR, Herrero P, Schechtman KB, Racette SB, Waggoner AD, Kisrieva-Ware Z, Dence C, Klein S, Marsala J, Meyer T, Gropler RJ. Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 2004;109:2191-2196.
-
(2004)
Circulation
, vol.109
, pp. 2191-2196
-
-
Peterson, L.R.1
Herrero, P.2
Schechtman, K.B.3
Racette, S.B.4
Waggoner, A.D.5
Kisrieva-Ware, Z.6
Dence, C.7
Klein, S.8
Marsala, J.9
Meyer, T.10
Gropler, R.J.11
-
36
-
-
31644445201
-
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus
-
Herrero P, Peterson LR, McGill JB, Matthew S, Lesniak D, Dence C, Gropler RJ. Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus. J Am Coll Cardiol 2006;47:598-604.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 598-604
-
-
Herrero, P.1
Peterson, L.R.2
McGill, J.B.3
Matthew, S.4
Lesniak, D.5
Dence, C.6
Gropler, R.J.7
-
37
-
-
84959180301
-
Lipotoxicity in obesity and diabetes-related cardiac dysfunction
-
Zlobine I, Gopal K, Ussher J.R. Lipotoxicity in obesity and diabetes-related cardiac dysfunction. Biochim Biophys Acta 2016;1860:1555-1568.
-
(2016)
Biochim Biophys Acta
, vol.1860
, pp. 1555-1568
-
-
Zlobine, I.1
Gopal, K.2
Ussher, J.R.3
-
38
-
-
84871536826
-
Adipose tissue biology and cardiomyopathy: Translational implications
-
Turer AT, Hill JA, Elmquist JK, Scherer PE. Adipose tissue biology and cardiomyopathy: Translational implications. Circ Res 2012;111:1565-1577.
-
(2012)
Circ Res
, vol.111
, pp. 1565-1577
-
-
Turer, A.T.1
Hill, J.A.2
Elmquist, J.K.3
Scherer, P.E.4
-
39
-
-
80052341422
-
Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling
-
Essick EE, Ouchi N, Wilson RM, Ohashi K, Ghobrial J, Shibata R, Pimentel DR, Sam F. Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol 2011;301:H984-993.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. H984-993
-
-
Essick, E.E.1
Ouchi, N.2
Wilson, R.M.3
Ohashi, K.4
Ghobrial, J.5
Shibata, R.6
Pimentel, D.R.7
Sam, F.8
-
40
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-1808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
41
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003;112:1821-1830.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
42
-
-
79957957647
-
PPARalpha agonist prevented the apoptosis induced by glucose and fatty acid in neonatal cardiomyocytes
-
Nan WQ, Shan TQ, Qian X, Ping W, Bing GA, Ying LL. PPARalpha agonist prevented the apoptosis induced by glucose and fatty acid in neonatal cardiomyocytes. J Endocrinol Invest 2011;34:271-275.
-
(2011)
J Endocrinol Invest
, vol.34
, pp. 271-275
-
-
Nan, W.Q.1
Shan, T.Q.2
Qian, X.3
Ping, W.4
Bing, G.A.5
Ying, L.L.6
-
43
-
-
62549165886
-
The signal transduction pathway of PKC/NF-kappa B/c-fos may be involved in the influence of high glucose on the cardiomyocytes of neonatal rats
-
Min W, Bin ZW, Quan ZB, Hui ZJ, Sheng FG. The signal transduction pathway of PKC/NF-kappa B/c-fos may be involved in the influence of high glucose on the cardiomyocytes of neonatal rats. Cardiovasc Diabetol 2009;8:8.
-
(2009)
Cardiovasc Diabetol
, vol.8
, pp. 8
-
-
Min, W.1
Bin, Z.W.2
Quan, Z.B.3
Hui, Z.J.4
Sheng, F.G.5
-
44
-
-
52649114296
-
Cardiac inflammation associated with a western diet is mediated via activation of RAGE by AGEs
-
Tikellis C, Thomas MC, Harcourt BE, Coughlan MT, Pete J, Bialkowski K, Tan A, Bierhaus A, Cooper ME, Forbes JM. Cardiac inflammation associated with a western diet is mediated via activation of RAGE by AGEs. Am J Physiol Endocrinol Metab 2008;295:E323-330.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. E323-330
-
-
Tikellis, C.1
Thomas, M.C.2
Harcourt, B.E.3
Coughlan, M.T.4
Pete, J.5
Bialkowski, K.6
Tan, A.7
Bierhaus, A.8
Cooper, M.E.9
Forbes, J.M.10
-
45
-
-
70350560556
-
Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMPactivated protein kinase in the heart
-
Ko HJ, Zhang Z, Jung DY, Jun JY, Ma Z, Jones KE, Chan SY, Kim JK. Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMPactivated protein kinase in the heart. Diabetes 2009;58:2536-2546.
-
(2009)
Diabetes
, vol.58
, pp. 2536-2546
-
-
Ko, H.J.1
Zhang, Z.2
Jung, D.Y.3
Jun, J.Y.4
Ma, Z.5
Jones, K.E.6
Chan, S.Y.7
Kim, J.K.8
-
46
-
-
28744441357
-
Transgenic activation of the kallikreinkinin system inhibits intramyocardial inflammation, endothelial dysfunction and oxidative stress in experimental diabetic cardiomyopathy
-
Tschope C, Walther T, Escher F, Spillmann F, Du J, Altmann C, Schimke I, Bader M, Sanchez-Ferrer CF, Schultheiss HP, Noutsias M. Transgenic activation of the kallikreinkinin system inhibits intramyocardial inflammation, endothelial dysfunction and oxidative stress in experimental diabetic cardiomyopathy. FASEB J 2005;19:2057-2059.
-
(2005)
FASEB J
, vol.19
, pp. 2057-2059
-
-
Tschope, C.1
Walther, T.2
Escher, F.3
Spillmann, F.4
Du, J.5
Altmann, C.6
Schimke, I.7
Bader, M.8
Sanchez-Ferrer, C.F.9
Schultheiss, H.P.10
Noutsias, M.11
-
47
-
-
35348835422
-
Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy
-
Westermann D, Van Linthout S, Dhayat S, Dhayat N, Schmidt A, Noutsias M, Song XY, Spillmann F, Riad A, Schultheiss HP, Tschope C. Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy. Basic Res Cardiol 2007;102:500-507.
-
(2007)
Basic Res Cardiol
, vol.102
, pp. 500-507
-
-
Westermann, D.1
Van Linthout, S.2
Dhayat, S.3
Dhayat, N.4
Schmidt, A.5
Noutsias, M.6
Song, X.Y.7
Spillmann, F.8
Riad, A.9
Schultheiss, H.P.10
Tschope, C.11
-
48
-
-
84927700592
-
NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model
-
Luo B, Li B, Wang W, Liu X, Xia Y, Zhang C, Zhang M, Zhang Y, An F. NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model. PLoS One 2014;9:e104771.
-
(2014)
PLoS One
, vol.9
, pp. e104771
-
-
Luo, B.1
Li, B.2
Wang, W.3
Liu, X.4
Xia, Y.5
Zhang, C.6
Zhang, M.7
Zhang, Y.8
An, F.9
-
49
-
-
84926433832
-
Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db/db mice
-
Plante E, Menaouar A, Danalache BA, Yip D, Broderick TL, Chiasson JL, Jankowski M, Gutkowska J. Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db/db mice. Endocrinology 2015;156:1416-1428.
-
(2015)
Endocrinology
, vol.156
, pp. 1416-1428
-
-
Plante, E.1
Menaouar, A.2
Danalache, B.A.3
Yip, D.4
Broderick, T.L.5
Chiasson, J.L.6
Jankowski, M.7
Gutkowska, J.8
-
50
-
-
84924251699
-
Uric acid promotes left ventricular diastolic dysfunction in mice fed a western diet
-
Jia G, Habibi J, Bostick BP, Ma L, DeMarco VG, Aroor AR, Hayden MR, Whaley-Connell AT, Sowers J.R. Uric acid promotes left ventricular diastolic dysfunction in mice fed a western diet. Hypertension 2015;65:531-539.
-
(2015)
Hypertension
, vol.65
, pp. 531-539
-
-
Jia, G.1
Habibi, J.2
Bostick, B.P.3
Ma, L.4
DeMarco, V.G.5
Aroor, A.R.6
Hayden, M.R.7
Whaley-Connell, A.T.8
Sowers, J.R.9
-
51
-
-
84906901859
-
BMP-7 attenuates adverse cardiac remodeling mediated through M2 macrophages in prediabetic cardiomyopathy
-
Urbina P, Singla DK. BMP-7 attenuates adverse cardiac remodeling mediated through M2 macrophages in prediabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 2014;307:H762-772.
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.307
, pp. H762-772
-
-
Urbina, P.1
Singla, D.K.2
-
52
-
-
0025286817
-
Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
-
Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990;323:236-241.
-
(1990)
N Engl J Med
, vol.323
, pp. 236-241
-
-
Levine, B.1
Kalman, J.2
Mayer, L.3
Fillit, H.M.4
Packer, M.5
-
53
-
-
0030226423
-
Basic mechanisms in heart failure: The cytokine hypothesis
-
Seta Y, Shan K, Bozkurt B, Oral H, Mann DL. Basic mechanisms in heart failure: The cytokine hypothesis. J Card Fail 1996;2:243-249.
-
(1996)
J Card Fail
, vol.2
, pp. 243-249
-
-
Seta, Y.1
Shan, K.2
Bozkurt, B.3
Oral, H.4
Mann, D.L.5
-
54
-
-
0035942264
-
Cytokines and cytokine receptors in advanced heart failure: An analysis of the cytokine database from the vesnarinone trial (VEST)
-
Deswal A, Petersen NJ, Feldman AM, Young JB, White BG, Mann DL. Cytokines and cytokine receptors in advanced heart failure: An analysis of the cytokine database from the vesnarinone trial (VEST). Circulation 2001;103:2055-2059.
-
(2001)
Circulation
, vol.103
, pp. 2055-2059
-
-
Deswal, A.1
Petersen, N.J.2
Feldman, A.M.3
Young, J.B.4
White, B.G.5
Mann, D.L.6
-
55
-
-
0037195727
-
Inflammatory mediators and the failing heart: Past, present, the foreseeable future
-
Mann DL. Inflammatory mediators and the failing heart: Past, present, the foreseeable future. Circ Res 2002;91:988-998.
-
(2002)
Circ Res
, vol.91
, pp. 988-998
-
-
Mann, D.L.1
-
56
-
-
84959374845
-
The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure
-
Briasoulis A, Androulakis E, Christophides T, Tousoulis D. The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure. Heart Fail Rev 2016;21:169-176.
-
(2016)
Heart Fail Rev
, vol.21
, pp. 169-176
-
-
Briasoulis, A.1
Androulakis, E.2
Christophides, T.3
Tousoulis, D.4
-
57
-
-
33750515851
-
Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response
-
Boyd JH, Mathur S, Wang Y, Bateman RM, Walley KR. Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response. Cardiovasc Res 2006;72:384-393.
-
(2006)
Cardiovasc Res
, vol.72
, pp. 384-393
-
-
Boyd, J.H.1
Mathur, S.2
Wang, Y.3
Bateman, R.M.4
Walley, K.R.5
-
58
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R. Origin and physiological roles of inflammation. Nature 2008;454:428-435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
59
-
-
84939247051
-
Innate immunity and the failing heart: The cytokine hypothesis revisited
-
Mann DL. Innate immunity and the failing heart: The cytokine hypothesis revisited. Circ Res 2015;116:1254-1268.
-
(2015)
Circ Res
, vol.116
, pp. 1254-1268
-
-
Mann, D.L.1
-
60
-
-
84975887140
-
Chronic heart failure and inflammation: What do we really know
-
Dick SA, Epelman S. Chronic heart failure and inflammation: What do we really know Circ Res 2016;119:159-176.
-
(2016)
Circ Res
, vol.119
, pp. 159-176
-
-
Dick, S.A.1
Epelman, S.2
-
61
-
-
84912139381
-
Ly6C(low) and not Ly6C(high) macrophages accumulate first in the heart in a model of murine pressure-overload
-
Weisheit C, Zhang Y, Faron A, Kopke O, Weisheit G, Steinstrasser A, Frede S, Meyer R, Boehm O, Hoeft A, Kurts C, Baumgarten G. Ly6C(low) and not Ly6C(high) macrophages accumulate first in the heart in a model of murine pressure-overload. PLoS One 2014;9:e112710.
-
(2014)
PLoS One
, vol.9
, pp. e112710
-
-
Weisheit, C.1
Zhang, Y.2
Faron, A.3
Kopke, O.4
Weisheit, G.5
Steinstrasser, A.6
Frede, S.7
Meyer, R.8
Boehm, O.9
Hoeft, A.10
Kurts, C.11
Baumgarten, G.12
-
62
-
-
77957078371
-
Endoplasmic reticulum stress and inflammation in obesity and diabetes
-
Hummasti S, Hotamisligil GS. Endoplasmic reticulum stress and inflammation in obesity and diabetes. Circ Res 2010;107:579-591.
-
(2010)
Circ Res
, vol.107
, pp. 579-591
-
-
Hummasti, S.1
Hotamisligil, G.S.2
-
63
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through toll-like receptor 4
-
Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through toll-like receptor 4. J Biol Chem 2001;276:16683-16689.
-
(2001)
J Biol Chem
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
64
-
-
33745187112
-
Activation of toll-like receptor 4 is associated with insulin resistance in adipocytes
-
Song MJ, Kim KH, Yoon JM, Kim JB. Activation of toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006;346: 739-745.
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 739-745
-
-
Song, M.J.1
Kim, K.H.2
Yoon, J.M.3
Kim, J.B.4
-
65
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 2007;282:35279-35292.
-
(2007)
J Biol Chem
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
66
-
-
84986905526
-
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
-
Nishimoto S, Fukuda D, Higashikuni Y, Tanaka K, Hirata Y, Murata C, Kim-Kaneyama JR, Sato F, Bando M, Yagi S, Soeki T, Hayashi T, Imoto I, Sakaue H, Shimabukuro M, Sata M. Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance. Sci Adv 2016;2:e1501332.
-
(2016)
Sci Adv
, vol.2
, pp. e1501332
-
-
Nishimoto, S.1
Fukuda, D.2
Higashikuni, Y.3
Tanaka, K.4
Hirata, Y.5
Murata, C.6
Kim-Kaneyama, J.R.7
Sato, F.8
Bando, M.9
Yagi, S.10
Soeki, T.11
Hayashi, T.12
Imoto, I.13
Sakaue, H.14
Shimabukuro, M.15
Sata, M.16
-
67
-
-
79955038882
-
Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Fatty acidinduced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 2011;12:408-415.
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
68
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011;12:222-230.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
69
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 2012;36:401-414.
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
70
-
-
84865497318
-
Adipocytes secrete leukotrienes: Contribution to obesity-associated inflammation and insulin resistance in mice
-
Mothe-Satney I, Filloux C, Amghar H, Pons C, Bourlier V, Galitzky J, Grimaldi PA, Feral CC, Bouloumie A, Van Obberghen E, Neels JG. Adipocytes secrete leukotrienes: Contribution to obesity-associated inflammation and insulin resistance in mice. Diabetes 2012;61:2311-2319.
-
(2012)
Diabetes
, vol.61
, pp. 2311-2319
-
-
Mothe-Satney, I.1
Filloux, C.2
Amghar, H.3
Pons, C.4
Bourlier, V.5
Galitzky, J.6
Grimaldi, P.A.7
Feral, C.C.8
Bouloumie, A.9
Van Obberghen, E.10
Neels, J.G.11
-
71
-
-
84866410100
-
TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes
-
Dong B, Qi D, Yang L, Huang Y, Xiao X, Tai N, Wen L, Wong FS. TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes. Am J Physiol Heart Circ Physiol 2012;303:H732-H742.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
, pp. H732-H742
-
-
Dong, B.1
Qi, D.2
Yang, L.3
Huang, Y.4
Xiao, X.5
Tai, N.6
Wen, L.7
Wong, F.S.8
-
72
-
-
78650043221
-
Prevention of hyperglycemiainduced myocardial apoptosis by gene silencing of toll-like receptor-4
-
Zhang Y, Peng T, Zhu H, Zheng X, Zhang X, Jiang N, Cheng X, Lai X, Shunnar A, Singh M, Riordan N, Bogin V, Tong N, Min WP. Prevention of hyperglycemiainduced myocardial apoptosis by gene silencing of toll-like receptor-4. J Transl Med 2010;8:133.
-
(2010)
J Transl Med
, vol.8
, pp. 133
-
-
Zhang, Y.1
Peng, T.2
Zhu, H.3
Zheng, X.4
Zhang, X.5
Jiang, N.6
Cheng, X.7
Lai, X.8
Shunnar, A.9
Singh, M.10
Riordan, N.11
Bogin, V.12
Tong, N.13
Min, W.P.14
-
73
-
-
0035895913
-
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
-
Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 2001;276:5197-5203.
-
(2001)
J Biol Chem
, vol.276
, pp. 5197-5203
-
-
Frantz, S.1
Kelly, R.A.2
Bourcier, T.3
-
74
-
-
84988566040
-
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing
-
Chen Q, Sun L, Chen ZJ. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing. Nat Immunol 2016;17:1142-1149.
-
(2016)
Nat Immunol
, vol.17
, pp. 1142-1149
-
-
Chen, Q.1
Sun, L.2
Chen, Z.J.3
-
75
-
-
84956909651
-
Mitochondrial dysfunction in fatty acid oxidation disorders: Insights from human and animal studies
-
Wajner M, Amaral AU. Mitochondrial dysfunction in fatty acid oxidation disorders: Insights from human and animal studies. Biosci Rep 2016;36:e00281.
-
(2016)
Biosci Rep
, vol.36
, pp. e00281
-
-
Wajner, M.1
Amaral, A.U.2
-
76
-
-
0021910272
-
Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, from human hearts
-
Schaper J, Meiser E, Stammler G. Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, from human hearts. Circ Res 1985;56:377-391.
-
(1985)
Circ Res
, vol.56
, pp. 377-391
-
-
Schaper, J.1
Meiser, E.2
Stammler, G.3
-
77
-
-
84883374607
-
Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria
-
Rindler PM, Crewe CL, Fernandes J, Kinter M, Szweda LI. Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria. Am J Physiol Heart Circ Physiol 2013;305:H634-643.
-
(2013)
Am J Physiol Heart Circ Physiol
, vol.305
, pp. H634-643
-
-
Rindler, P.M.1
Crewe, C.L.2
Fernandes, J.3
Kinter, M.4
Szweda, L.I.5
-
78
-
-
84930670567
-
Mitochondrial dynamics in diabetic cardiomyopathy
-
Galloway CA, Yoon Y. Mitochondrial dynamics in diabetic cardiomyopathy. Antioxid Redox Signal 2015;22:1545-1562.
-
(2015)
Antioxid Redox Signal
, vol.22
, pp. 1545-1562
-
-
Galloway, C.A.1
Yoon, Y.2
-
79
-
-
84919822611
-
Autophagy and mitophagy in diabetic cardiomyopathy
-
Kobayashi S, Liang Q. Autophagy and mitophagy in diabetic cardiomyopathy. Biochim Biophys Acta 2015;1852:252-261.
-
(2015)
Biochim Biophys Acta
, vol.1852
, pp. 252-261
-
-
Kobayashi, S.1
Liang, Q.2
-
80
-
-
33644766038
-
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
-
Shen X, Zheng S, Metreveli NS, Epstein PN. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes 2006;55:798-805.
-
(2006)
Diabetes
, vol.55
, pp. 798-805
-
-
Shen, X.1
Zheng, S.2
Metreveli, N.S.3
Epstein, P.N.4
-
81
-
-
2342563763
-
Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes
-
Ye G, Metreveli NS, Donthi RV, Xia S, Xu M, Carlson EC, Epstein PN. Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. Diabetes 2004;53:1336-1343.
-
(2004)
Diabetes
, vol.53
, pp. 1336-1343
-
-
Ye, G.1
Metreveli, N.S.2
Donthi, R.V.3
Xia, S.4
Xu, M.5
Carlson, E.C.6
Epstein, P.N.7
-
82
-
-
7444220738
-
Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats
-
Fiordaliso F, Bianchi R, Staszewsky L, Cuccovillo I, Doni M, Laragione T, Salio M, Savino C, Melucci S, Santangelo F, Scanziani E, Masson S, Ghezzi P, Latini R. Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats. J Mol Cell Cardiol 2004;37:959-968.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 959-968
-
-
Fiordaliso, F.1
Bianchi, R.2
Staszewsky, L.3
Cuccovillo, I.4
Doni, M.5
Laragione, T.6
Salio, M.7
Savino, C.8
Melucci, S.9
Santangelo, F.10
Scanziani, E.11
Masson, S.12
Ghezzi, P.13
Latini, R.14
-
83
-
-
78649984380
-
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory and cell death signaling pathways in diabetic cardiomyopathy
-
Rajesh M, Mukhopadhyay P, Batkai S, Patel V, Saito K, Matsumoto S, Kashiwaya Y, Horvath B, Mukhopadhyay B, Becker L, Hasko G, Liaudet L, Wink DA, Veves A, Mechoulam R, Pacher P. Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory and cell death signaling pathways in diabetic cardiomyopathy. J Am Coll Cardiol 2010;56:2115-2125.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 2115-2125
-
-
Rajesh, M.1
Mukhopadhyay, P.2
Batkai, S.3
Patel, V.4
Saito, K.5
Matsumoto, S.6
Kashiwaya, Y.7
Horvath, B.8
Mukhopadhyay, B.9
Becker, L.10
Hasko, G.11
Liaudet, L.12
Wink, D.A.13
Veves, A.14
Mechoulam, R.15
Pacher, P.16
-
84
-
-
74249092946
-
NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes
-
Mariappan N, Elks CM, Sriramula S, Guggilam A, Liu Z, Borkhsenious O, Francis J. NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes. Cardiovasc Res 2010;85:473-483.
-
(2010)
Cardiovasc Res
, vol.85
, pp. 473-483
-
-
Mariappan, N.1
Elks, C.M.2
Sriramula, S.3
Guggilam, A.4
Liu, Z.5
Borkhsenious, O.6
Francis, J.7
-
85
-
-
0033900011
-
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure
-
Ferdinandy P, Danial H, Ambrus I, Rothery RA, Schulz R. Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ Res 2000;87:241-247.
-
(2000)
Circ Res
, vol.87
, pp. 241-247
-
-
Ferdinandy, P.1
Danial, H.2
Ambrus, I.3
Rothery, R.A.4
Schulz, R.5
-
86
-
-
33747598024
-
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo
-
Levrand S, Vannay-Bouchiche C, Pesse B, Pacher P, Feihl F, Waeber B, Liaudet L. Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo. Free Radic Biol Med 2006;41:886-895.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 886-895
-
-
Levrand, S.1
Vannay-Bouchiche, C.2
Pesse, B.3
Pacher, P.4
Feihl, F.5
Waeber, B.6
Liaudet, L.7
-
87
-
-
72949110566
-
Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure
-
Bugger H, Schwarzer M, Chen D, Schrepper A, Amorim PA, Schoepe M, Nguyen TD, Mohr FW, Khalimonchuk O, Weimer BC, Doenst T. Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure. Cardiovasc Res 2010;85:376-384.
-
(2010)
Cardiovasc Res
, vol.85
, pp. 376-384
-
-
Bugger, H.1
Schwarzer, M.2
Chen, D.3
Schrepper, A.4
Amorim, P.A.5
Schoepe, M.6
Nguyen, T.D.7
Mohr, F.W.8
Khalimonchuk, O.9
Weimer, B.C.10
Doenst, T.11
-
88
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, Taniike M, Omiya S, Mizote I, Matsumura Y, Asahi M, Nishida K, Hori M, Mizushima N, Otsu K. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 2007;13:619-624.
-
(2007)
Nat Med
, vol.13
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
Omiya, S.7
Mizote, I.8
Matsumura, Y.9
Asahi, M.10
Nishida, K.11
Hori, M.12
Mizushima, N.13
Otsu, K.14
-
89
-
-
84916642028
-
The role of autophagic degradation in the heart
-
Nishida K, Taneike M, Otsu K. The role of autophagic degradation in the heart. J Mol Cell Cardiol 2015;78:73-79.
-
(2015)
J Mol Cell Cardiol
, vol.78
, pp. 73-79
-
-
Nishida, K.1
Taneike, M.2
Otsu, K.3
-
90
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, type 2 diabetes. Science 2004;306:457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
91
-
-
84878687221
-
Endoplasmic reticulum is at the crossroads of autophagy, inflammation, apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus
-
Su J, Zhou L, Kong X, Yang X, Xiang X, Zhang Y, Li X, Sun L. Endoplasmic reticulum is at the crossroads of autophagy, inflammation, apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus. J Diabetes Res 2013;2013:193461.
-
(2013)
J Diabetes Res
, vol.2013
, pp. 193461
-
-
Su, J.1
Zhou, L.2
Kong, X.3
Yang, X.4
Xiang, X.5
Zhang, Y.6
Li, X.7
Sun, L.8
-
92
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS, Obin MS. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005;46:2347-2355.
-
(2005)
J Lipid Res
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
Wang, S.7
Fortier, M.8
Greenberg, A.S.9
Obin, M.S.10
-
93
-
-
10044268430
-
Altered cardiac calcium handling in diabetes
-
Belke DD, Dillmann WH. Altered cardiac calcium handling in diabetes. Curr Hypertens Rep 2004;6:424-429.
-
(2004)
Curr Hypertens Rep
, vol.6
, pp. 424-429
-
-
Belke, D.D.1
Dillmann, W.H.2
-
95
-
-
33644783906
-
Mechanisms of [Ca2\+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice
-
Pereira L, Matthes J, Schuster I, Valdivia HH, Herzig S, Richard S, Gomez AM. Mechanisms of [Ca2\+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice. Diabetes 2006;55:608-615.
-
(2006)
Diabetes
, vol.55
, pp. 608-615
-
-
Pereira, L.1
Matthes, J.2
Schuster, I.3
Valdivia, H.H.4
Herzig, S.5
Richard, S.6
Gomez, A.M.7
-
96
-
-
33845657896
-
Dyssynchronous (non-uniform) Ca2\+ release in myocytes from streptozotocin-induced diabetic rats
-
Shao CH, Rozanski GJ, Patel KP, Bidasee KR. Dyssynchronous (non-uniform) Ca2\+ release in myocytes from streptozotocin-induced diabetic rats. J Mol Cell Cardiol 2007;42:234-246.
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 234-246
-
-
Shao, C.H.1
Rozanski, G.J.2
Patel, K.P.3
Bidasee, K.R.4
-
97
-
-
84900031278
-
Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation
-
Mori J, Patel VB, Abo Alrob O, Basu R, Altamimi T, Desaulniers J, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation. Circ Heart Fail 2014;7:327-339.
-
(2014)
Circ Heart Fail
, vol.7
, pp. 327-339
-
-
Mori, J.1
Patel, V.B.2
Abo Alrob, O.3
Basu, R.4
Altamimi, T.5
Desaulniers, J.6
Wagg, C.S.7
Kassiri, Z.8
Lopaschuk, G.D.9
Oudit, G.Y.10
-
98
-
-
33847342561
-
Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: The role of angiotensin type 1 receptor antagonism
-
Westermann D, Rutschow S, Jager S, Linderer A, Anker S, Riad A, Unger T, Schultheiss HP, Pauschinger M, Tschope C. Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: The role of angiotensin type 1 receptor antagonism. Diabetes 2007;56:641-646.
-
(2007)
Diabetes
, vol.56
, pp. 641-646
-
-
Westermann, D.1
Rutschow, S.2
Jager, S.3
Linderer, A.4
Anker, S.5
Riad, A.6
Unger, T.7
Schultheiss, H.P.8
Pauschinger, M.9
Tschope, C.10
-
99
-
-
84949921072
-
Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities
-
Russo I, Frangogiannis NG. Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities. J Mol Cell Cardiol 2016;90:84-93.
-
(2016)
J Mol Cell Cardiol
, vol.90
, pp. 84-93
-
-
Russo, I.1
Frangogiannis, N.G.2
-
100
-
-
84867724832
-
Mitochondria and mitophagy: The yin and yang of cell death control
-
Kubli DA, Gustafsson AB. Mitochondria and mitophagy: The yin and yang of cell death control. Circ Res 2012;111:1208-1221.
-
(2012)
Circ Res
, vol.111
, pp. 1208-1221
-
-
Kubli, D.A.1
Gustafsson, A.B.2
-
101
-
-
71449091240
-
Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: Inhibition of FoxO1-dependent expression of key autophagy genes by insulin
-
Liu HY, Han J, Cao SY, Hong T, Zhuo D, Shi J, Liu Z, Cao W. Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: Inhibition of FoxO1-dependent expression of key autophagy genes by insulin. J Biol Chem 2009;284:31484-31492.
-
(2009)
J Biol Chem
, vol.284
, pp. 31484-31492
-
-
Liu, H.Y.1
Han, J.2
Cao, S.Y.3
Hong, T.4
Zhuo, D.5
Shi, J.6
Liu, Z.7
Cao, W.8
-
102
-
-
78049486018
-
Autophagy in liver diseases
-
Rautou PE, Mansouri A, Lebrec D, Durand F, Valla D, Moreau R. Autophagy in liver diseases. J Hepatol 2010;53:1123-1134.
-
(2010)
J Hepatol
, vol.53
, pp. 1123-1134
-
-
Rautou, P.E.1
Mansouri, A.2
Lebrec, D.3
Durand, F.4
Valla, D.5
Moreau, R.6
-
103
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie Z, Lau K, Eby B, Lozano P, He C, Pennington B, Li H, Rathi S, Dong Y, Tian R, Kem D, Zou MH. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 2011;60:1770-1778.
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
Lau, K.2
Eby, B.3
Lozano, P.4
He, C.5
Pennington, B.6
Li, H.7
Rathi, S.8
Dong, Y.9
Tian, R.10
Kem, D.11
Zou, M.H.12
-
104
-
-
84884562299
-
Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy
-
Zhao Y, Zhang L, Qiao Y, Zhou X, Wu G, Wang L, Peng Y, Dong X, Huang H, Si L, Zhang X, Zhang L, Li J, Wang W, Zhou L, Gao X. Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy. PLoS One 2013;8:e75927.
-
(2013)
PLoS One
, vol.8
, pp. e75927
-
-
Zhao, Y.1
Zhang, L.2
Qiao, Y.3
Zhou, X.4
Wu, G.5
Wang, L.6
Peng, Y.7
Dong, X.8
Huang, H.9
Si, L.10
Zhang, X.11
Zhang, L.12
Li, J.13
Wang, W.14
Zhou, L.15
Gao, X.16
-
105
-
-
84857914471
-
Rheb is a critical regulator of autophagy during myocardial ischemia: Pathophysiological implications in obesity and metabolic syndrome
-
Sciarretta S, Zhai P, Shao D, Maejima Y, Robbins J, Volpe M, Condorelli G, Sadoshima J. Rheb is a critical regulator of autophagy during myocardial ischemia: Pathophysiological implications in obesity and metabolic syndrome. Circulation 2012;125:1134-1146.
-
(2012)
Circulation
, vol.125
, pp. 1134-1146
-
-
Sciarretta, S.1
Zhai, P.2
Shao, D.3
Maejima, Y.4
Robbins, J.5
Volpe, M.6
Condorelli, G.7
Sadoshima, J.8
-
106
-
-
84868628424
-
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
-
Russo SB, Baicu CF, Van Laer A, Geng T, Kasiganesan H, Zile MR, Cowart LA. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J Clin Invest 2012;122:3919-3930.
-
(2012)
J Clin Invest
, vol.122
, pp. 3919-3930
-
-
Russo, S.B.1
Baicu, C.F.2
Van Laer, A.3
Geng, T.4
Kasiganesan, H.5
Zile, M.R.6
Cowart, L.A.7
-
107
-
-
84962469698
-
MTOR hyperactivation by ablation of tuberous sclerosis complex 2 in the mouse heart induces cardiac dysfunction with the increased number of small mitochondria mediated through the down-regulation of autophagy
-
Taneike M, Nishida K, Omiya S, Zarrinpashneh E, Misaka T, Kitazume-Taneike R, Austin R, Takaoka M, Yamaguchi O, Gambello MJ, Shah AM, Otsu K. mTOR hyperactivation by ablation of tuberous sclerosis complex 2 in the mouse heart induces cardiac dysfunction with the increased number of small mitochondria mediated through the down-regulation of autophagy. PLoS One 2016;11:e0152628.
-
(2016)
PLoS One
, vol.11
, pp. e0152628
-
-
Taneike, M.1
Nishida, K.2
Omiya, S.3
Zarrinpashneh, E.4
Misaka, T.5
Kitazume-Taneike, R.6
Austin, R.7
Takaoka, M.8
Yamaguchi, O.9
Gambello, M.J.10
Shah, A.M.11
Otsu, K.12
-
108
-
-
78649413837
-
Mitochondrial fusion and fission in cell life and death
-
Westermann B. Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol 2010;11:872-884.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 872-884
-
-
Westermann, B.1
-
109
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 2008;27:433-446.
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
110
-
-
0021770656
-
Methylation pattern of mouse mitochondrial DNA
-
Pollack Y, Kasir J, Shemer R, Metzger S, Szyf M. Methylation pattern of mouse mitochondrial DNA. Nucleic Acids Res 1984;12:4811-4824.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 4811-4824
-
-
Pollack, Y.1
Kasir, J.2
Shemer, R.3
Metzger, S.4
Szyf, M.5
-
111
-
-
77952428203
-
Defective DNA replication impairs mitochondrial biogenesis in human failing hearts
-
Karamanlidis G, Nascimben L, Couper GS, Shekar PS, del Monte F, Tian R. Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ Res 2010;106:1541-1548.
-
(2010)
Circ Res
, vol.106
, pp. 1541-1548
-
-
Karamanlidis, G.1
Nascimben, L.2
Couper, G.S.3
Shekar, P.S.4
Del Monte, F.5
Tian, R.6
-
112
-
-
84937640559
-
Inflammatory markers and cardiometabolic diseases
-
Esser N, Paquot N, Scheen AJ. Inflammatory markers and cardiometabolic diseases. Acta Clin Belg 2015;70:193-199.
-
(2015)
Acta Clin Belg
, vol.70
, pp. 193-199
-
-
Esser, N.1
Paquot, N.2
Scheen, A.J.3
-
113
-
-
84878493642
-
Peroxisome proliferatoractivated receptors modulate cardiac dysfunction in diabetic cardiomyopathy
-
Lee TI, Kao YH, Chen YC, Huang JH, Hsiao FC, Chen YJ. Peroxisome proliferatoractivated receptors modulate cardiac dysfunction in diabetic cardiomyopathy. Diabetes Res Clin Pract 2013;100:330-339.
-
(2013)
Diabetes Res Clin Pract
, vol.100
, pp. 330-339
-
-
Lee, T.I.1
Kao, Y.H.2
Chen, Y.C.3
Huang, J.H.4
Hsiao, F.C.5
Chen, Y.J.6
-
114
-
-
84973520065
-
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice
-
Zhang J, Cheng Y, Gu J, Wang S, Zhou S, Wang Y, Tan Y, Feng W, Fu Y, Mellen N, Cheng R, Ma J, Zhang C, Li Z, Cai L. Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice. Clin Sci (Lond) 2016;130:625-641.
-
(2016)
Clin Sci (Lond)
, vol.130
, pp. 625-641
-
-
Zhang, J.1
Cheng, Y.2
Gu, J.3
Wang, S.4
Zhou, S.5
Wang, Y.6
Tan, Y.7
Feng, W.8
Fu, Y.9
Mellen, N.10
Cheng, R.11
Ma, J.12
Zhang, C.13
Li, Z.14
Cai, L.15
-
115
-
-
84937532657
-
Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases
-
Zordoky BN, Robertson IM, Dyck J.R. Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases. Biochim Biophys Acta 2015;1852:1155-1177.
-
(2015)
Biochim Biophys Acta
, vol.1852
, pp. 1155-1177
-
-
Zordoky, B.N.1
Robertson, I.M.2
Dyck, J.R.3
|