메뉴 건너뛰기




Volumn 116, Issue 7, 2015, Pages 1254-1268

Innate immunity and the failing heart: The cytokine hypothesis revisited

Author keywords

Clinical trials; Heart failure; Inflammation; Innate immunity

Indexed keywords

ALLOPURINOL; BIOLOGICAL MARKER; CYTOKINE; DEXAMETHASONE; ETANERCEPT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN G; INFLIXIMAB; METHOTREXATE; OMEGA 3 FATTY ACID; OXIPURINOL; PENTOXIFYLLINE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; THALIDOMIDE; ANTIINFLAMMATORY AGENT; AUTOANTIBODY; IMMUNOLOGIC FACTOR; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; PATTERN RECOGNITION RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84939247051     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.302317     Document Type: Review
Times cited : (538)

References (89)
  • 1
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B, Kalman J, Mayer L, Fillit HM, Packer M, Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990; 323: 236-241. doi: 10.1056/NEJM199007263230405.
    • (1990) N Engl J Med , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3    Fillit, H.M.4    Packer, M.5
  • 3
    • 0037195727 scopus 로고    scopus 로고
    • Inflammatory mediators and the failing heart: Past, present, and the foreseeable future
    • Mann DL, Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 2002 91 988 998
    • (2002) Circ Res , vol.91 , pp. 988-998
    • Mann, D.L.1
  • 4
    • 11144355760 scopus 로고    scopus 로고
    • Targeted anti-cytokine therapy in patients with chronic heart failure: Results of the Randomized EtaNcercept Worldwide evALuation (RENEWAL)
    • Mann DL, McMurray JJV, Packer M, Targeted anti-cytokine therapy in patients with chronic heart failure: results of the Randomized EtaNcercept Worldwide evALuation (RENEWAL). Circulation 2004; 109: 1594-1602. doi: 10.1161/01.CIR.0000124490.27666.B2.
    • (2004) Circulation , vol.109 , pp. 1594-1602
    • Mann, D.L.1    McMurray, J.J.V.2    Packer, M.3
  • 5
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: Results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
    • Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT, Anti-TNF Therapy Against Congestive Heart Failure Investigators Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation 2003; 107: 3133-3140. doi: 10.1161/01.CIR.0000077913.60364.D2.
    • (2003) Circulation , vol.107 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 6
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R, Origin and physiological roles of inflammation. Nature 2008; 454: 428-435. doi: 10.1038/nature07201.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 7
    • 0013065280 scopus 로고    scopus 로고
    • Stress-activated cytokines and the heart: From adaptation to maladaptation
    • Mann DL, Stress-activated cytokines and the heart: from adaptation to maladaptation. Annu Rev Physiol 2003; 65: 81-101. doi: 10.1146/annurev.physiol.65.092101.142249.
    • (2003) Annu Rev Physiol , vol.65 , pp. 81-101
    • Mann, D.L.1
  • 8
    • 0025724055 scopus 로고
    • The immunological self: A centenary perspective
    • Tauber AI, The immunological self: a centenary perspective. Perspect Biol Med 1991 35 74 86
    • (1991) Perspect Biol Med , vol.35 , pp. 74-86
    • Tauber, A.I.1
  • 12
    • 19644362276 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human toll-like receptors and related genes
    • Nishimura M, Naito S, Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharm Bull 2005 28 886 892
    • (2005) Biol Pharm Bull , vol.28 , pp. 886-892
    • Nishimura, M.1    Naito, S.2
  • 13
    • 0035895913 scopus 로고    scopus 로고
    • Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
    • Frantz S, Kelly RA, Bourcier T, Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 2001; 276: 5197-5203. doi: 10.1074/jbc.M009160200.
    • (2001) J Biol Chem , vol.276 , pp. 5197-5203
    • Frantz, S.1    Kelly, R.A.2    Bourcier, T.3
  • 15
    • 0842285548 scopus 로고    scopus 로고
    • Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices
    • Birks EJ, Felkin LE, Banner NR, Khaghani A, Barton PJ, Yacoub MH, Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices. J Heart Lung Transplant 2004; 23: 228-235. doi: 10.1016/S1053-2498(03)00106-2.
    • (2004) J Heart Lung Transplant , vol.23 , pp. 228-235
    • Birks, E.J.1    Felkin, L.E.2    Banner, N.R.3    Khaghani, A.4    Barton, P.J.5    Yacoub, M.H.6
  • 17
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O, Akira S, Pattern recognition receptors and inflammation. Cell 2010; 140: 805-820. doi: 10.1016/j.cell.2010.01.022.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 19
    • 66849089729 scopus 로고    scopus 로고
    • Unleashing the therapeutic potential of NOD-like receptors
    • Geddes K, Magalhães JG, Girardin SE, Unleashing the therapeutic potential of NOD-like receptors. Nat Rev Drug Discov 2009; 8: 465-479. doi: 10.1038/nrd2783.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 465-479
    • Geddes, K.1    Magalhães, J.G.2    Girardin, S.E.3
  • 20
    • 79951679204 scopus 로고    scopus 로고
    • Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
    • Kawaguchi M, Takahashi M, Hata T, Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011; 123: 594-604. doi: 10.1161/CIRCULATIONAHA.110.982777.
    • (2011) Circulation , vol.123 , pp. 594-604
    • Kawaguchi, M.1    Takahashi, M.2    Hata, T.3
  • 22
    • 0037035444 scopus 로고    scopus 로고
    • Angiotensin II induces tumor necrosis factor biosynthesis in the adult mammalian heart through a protein kinase C-dependent pathway
    • Kalra D, Sivasubramanian N, Mann DL, Angiotensin II induces tumor necrosis factor biosynthesis in the adult mammalian heart through a protein kinase C-dependent pathway. Circulation 2002 105 2198 2205
    • (2002) Circulation , vol.105 , pp. 2198-2205
    • Kalra, D.1    Sivasubramanian, N.2    Mann, D.L.3
  • 23
    • 0034705111 scopus 로고    scopus 로고
    • Chronic beta-adrenergic stimulation induces myocardial proinflammatory cytokine expression
    • Murray DR, Prabhu SD, Chandrasekar B, Chronic beta-adrenergic stimulation induces myocardial proinflammatory cytokine expression. Circulation 2000 101 2338 2341
    • (2000) Circulation , vol.101 , pp. 2338-2341
    • Murray, D.R.1    Prabhu, S.D.2    Chandrasekar, B.3
  • 24
    • 0030226423 scopus 로고    scopus 로고
    • Basic mechanisms in heart failure: The cytokine hypothesis
    • Seta Y, Shan K, Bozkurt B, Oral H, Mann DL, Basic mechanisms in heart failure: the cytokine hypothesis. J Card Fail 1996 2 243 249
    • (1996) J Card Fail , vol.2 , pp. 243-249
    • Seta, Y.1    Shan, K.2    Bozkurt, B.3    Oral, H.4    Mann, D.L.5
  • 25
    • 10644266787 scopus 로고    scopus 로고
    • Cytokine-induced modulation of cardiac function
    • Prabhu SD, Cytokine-induced modulation of cardiac function. Circ Res 2004; 95: 1140-1153. doi: 10.1161/01.RES.0000150734.79804.92.
    • (2004) Circ Res , vol.95 , pp. 1140-1153
    • Prabhu, S.D.1
  • 26
    • 0032890967 scopus 로고    scopus 로고
    • Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha
    • Franco F, Thomas GD, Giroir B, Bryant D, Bullock MC, Chwialkowski MC, Victor RG, Peshock RM, Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation 1999 99 448 454
    • (1999) Circulation , vol.99 , pp. 448-454
    • Franco, F.1    Thomas, G.D.2    Giroir, B.3    Bryant, D.4    Bullock, M.C.5    Chwialkowski, M.C.6    Victor, R.G.7    Peshock, R.M.8
  • 27
    • 0035957009 scopus 로고    scopus 로고
    • Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta
    • Pomerantz BJ, Reznikov LL, Harken AH, Dinarello CA, Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta. Proc Natl Acad Sci U S A 2001; 98: 2871-2876. doi: 10.1073/pnas.041611398.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2871-2876
    • Pomerantz, B.J.1    Reznikov, L.L.2    Harken, A.H.3    Dinarello, C.A.4
  • 28
    • 79955601433 scopus 로고    scopus 로고
    • The emerging role of innate immunity in the heart and vascular system: For whom the cell tolls
    • Mann DL, The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls. Circ Res 2011; 108: 1133-1145. doi: 10.1161/CIRCRESAHA.110.226936.
    • (2011) Circ Res , vol.108 , pp. 1133-1145
    • Mann, D.L.1
  • 31
    • 80855143703 scopus 로고    scopus 로고
    • The development of myocardial fibrosis in transgenic mice with targeted overexpression of tumor necrosis factor requires mast cell-fibroblast interactions
    • Zhang W, Chancey AL, Tzeng HP, Zhou Z, Lavine KJ, Gao F, Sivasubramanian N, Barger PM, Mann DL, The development of myocardial fibrosis in transgenic mice with targeted overexpression of tumor necrosis factor requires mast cell-fibroblast interactions. Circulation 2011; 124: 2106-2116. doi: 10.1161/CIRCULATIONAHA.111.052399.
    • (2011) Circulation , vol.124 , pp. 2106-2116
    • Zhang, W.1    Chancey, A.L.2    Tzeng, H.P.3    Zhou, Z.4    Lavine, K.J.5    Gao, F.6    Sivasubramanian, N.7    Barger, P.M.8    Mann, D.L.9
  • 32
    • 84880417197 scopus 로고    scopus 로고
    • Positioning of inflammatory biomarkers in the heart failure landscape
    • Hartupee J, Mann DL, Positioning of inflammatory biomarkers in the heart failure landscape. J Cardiovasc Transl Res 2013; 6: 485-492. doi: 10.1007/s12265-013-9467-y.
    • (2013) J Cardiovasc Transl Res , vol.6 , pp. 485-492
    • Hartupee, J.1    Mann, D.L.2
  • 33
    • 84865506658 scopus 로고    scopus 로고
    • Pentraxin-3 in chronic heart failure: The CORONA and GISSI-HF trials
    • Latini R, Gullestad L, Masson S, Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials. Eur J Heart Fail 2012; 14: 992-999. doi: 10.1093/eurjhf/hfs092.
    • (2012) Eur J Heart Fail , vol.14 , pp. 992-999
    • Latini, R.1    Gullestad, L.2    Masson, S.3
  • 34
    • 36549030340 scopus 로고    scopus 로고
    • Rosuvastatin in older patients with systolic heart failure
    • Kjekshus J, Apetrei E, Barrios V, CORONA Group Rosuvastatin in older patients with systolic heart failure. N Engl J Med 2007; 357: 2248-2261. doi: 10.1056/NEJMoa0706201.
    • (2007) N Engl J Med , vol.357 , pp. 2248-2261
    • Kjekshus, J.1    Apetrei, E.2    Barrios, V.3
  • 36
    • 53049095795 scopus 로고    scopus 로고
    • Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebo-controlled trial
    • Gissi-HF Investigators Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet 2008 372 1231 1239
    • (2008) Lancet , vol.372 , pp. 1231-1239
  • 37
    • 33644876159 scopus 로고    scopus 로고
    • Effect of thalidomide on cardiac remodeling in chronic heart failure: Results of a double-blind, placebo-controlled study
    • Gullestad L, Ueland T, Fjeld JG, Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study. Circulation 2005; 112: 3408-3414. doi: 10.1161/CIRCULATIONAHA.105.564971.
    • (2005) Circulation , vol.112 , pp. 3408-3414
    • Gullestad, L.1    Ueland, T.2    Fjeld, J.G.3
  • 40
    • 0035957035 scopus 로고    scopus 로고
    • Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: Results of a randomized study
    • Skudicky D, Bergemann A, Sliwa K, Candy G, Sareli P, Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: results of a randomized study. Circulation 2001 103 1083 1088
    • (2001) Circulation , vol.103 , pp. 1083-1088
    • Skudicky, D.1    Bergemann, A.2    Sliwa, K.3    Candy, G.4    Sareli, P.5
  • 41
    • 0032507428 scopus 로고    scopus 로고
    • Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy
    • Sliwa K, Skudicky D, Candy G, Wisenbaugh T, Sareli P, Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy. Lancet 1998; 351: 1091-1093. doi: 10.1016/S0140-6736(97)09338-0.
    • (1998) Lancet , vol.351 , pp. 1091-1093
    • Sliwa, K.1    Skudicky, D.2    Candy, G.3    Wisenbaugh, T.4    Sareli, P.5
  • 42
    • 0037112101 scopus 로고    scopus 로고
    • Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy
    • Sliwa K, Woodiwiss A, Candy G, Badenhorst D, Libhaber C, Norton G, Skudicky D, Sareli P, Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol 2002 90 1118 1122
    • (2002) Am J Cardiol , vol.90 , pp. 1118-1122
    • Sliwa, K.1    Woodiwiss, A.2    Candy, G.3    Badenhorst, D.4    Libhaber, C.5    Norton, G.6    Skudicky, D.7    Sareli, P.8
  • 43
    • 1242314227 scopus 로고    scopus 로고
    • Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: Results of a randomized study
    • Sliwa K, Woodiwiss A, Kone VN, Candy G, Badenhorst D, Norton G, Zambakides C, Peters F, Essop R, Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study. Circulation 2004; 109: 750-755. doi: 10.1161/01.CIR.0000112568.48837.60.
    • (2004) Circulation , vol.109 , pp. 750-755
    • Sliwa, K.1    Woodiwiss, A.2    Kone, V.N.3    Candy, G.4    Badenhorst, D.5    Norton, G.6    Zambakides, C.7    Peters, F.8    Essop, R.9
  • 44
    • 33847309058 scopus 로고    scopus 로고
    • Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure
    • Krum H, Ashton E, Reid C, Kalff V, Rogers J, Amarena J, Singh B, Tonkin A, Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure. J Card Fail 2007; 13: 1-7. doi: 10.1016/j.cardfail.2006.09.008.
    • (2007) J Card Fail , vol.13 , pp. 1-7
    • Krum, H.1    Ashton, E.2    Reid, C.3    Kalff, V.4    Rogers, J.5    Amarena, J.6    Singh, B.7    Tonkin, A.8
  • 45
    • 38149087638 scopus 로고    scopus 로고
    • Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): A placebo-controlled randomised trial
    • Torre-Amione G, Anker SD, Bourge RC, Advanced Chronic Heart Failure CLinical Assessment of Immune Modulation Therapy Investigators Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a placebo-controlled randomised trial. Lancet 2008; 371: 228-236. doi: 10.1016/S0140-6736(08)60134-8.
    • (2008) Lancet , vol.371 , pp. 228-236
    • Torre-Amione, G.1    Anker, S.D.2    Bourge, R.C.3
  • 48
    • 70450235125 scopus 로고    scopus 로고
    • The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: A randomized double-blind, placebo-controlled trial (METIS trial)
    • Moreira DM, Vieira JL, Gottschall CA, The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: a randomized double-blind, placebo-controlled trial (METIS trial). J Card Fail 2009; 15: 828-834. doi: 10.1016/j.cardfail.2009.06.439.
    • (2009) J Card Fail , vol.15 , pp. 828-834
    • Moreira, D.M.1    Vieira, J.L.2    Gottschall, C.A.3
  • 50
    • 0037112101 scopus 로고    scopus 로고
    • Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy
    • Sliwa K, Woodiwiss A, Candy G, Badenhorst D, Libhaber C, Norton G, Skudicky D, Sareli P, Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol 2002 90 1118 1122
    • (2002) Am J Cardiol , vol.90 , pp. 1118-1122
    • Sliwa, K.1    Woodiwiss, A.2    Candy, G.3    Badenhorst, D.4    Libhaber, C.5    Norton, G.6    Skudicky, D.7    Sareli, P.8
  • 51
    • 0033808449 scopus 로고    scopus 로고
    • Reduction in Fas/APO-1 plasma concentrations correlates with improvement in left ventricular function in patients with idiopathic dilated cardiomyopathy treated with pentoxifylline
    • Skudicky D, Sliwa K, Bergemann A, Candy G, Sareli P, Reduction in Fas/APO-1 plasma concentrations correlates with improvement in left ventricular function in patients with idiopathic dilated cardiomyopathy treated with pentoxifylline. Heart 2000 84 438 439
    • (2000) Heart , vol.84 , pp. 438-439
    • Skudicky, D.1    Sliwa, K.2    Bergemann, A.3    Candy, G.4    Sareli, P.5
  • 52
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira AL, Sampaio EP, Zmuidzinas A, Frindt P, Smith KA, Kaplan G, Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med 1993 177 1675 1680
    • (1993) J Exp Med , vol.177 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 53
    • 0036774209 scopus 로고    scopus 로고
    • Preclinical and clinical assessment of the safety and potential efficacy of thalidomide in heart failure
    • Agoston I, Dibbs ZI, Wang F, Muller G, Zeldis JB, Mann DL, Bozkurt B, Preclinical and clinical assessment of the safety and potential efficacy of thalidomide in heart failure. J Card Fail 2002 8 306 314
    • (2002) J Card Fail , vol.8 , pp. 306-314
    • Agoston, I.1    Dibbs, Z.I.2    Wang, F.3    Muller, G.4    Zeldis, J.B.5    Mann, D.L.6    Bozkurt, B.7
  • 54
    • 84884441362 scopus 로고    scopus 로고
    • Activation of inflammatory mediators in heart failure
    • 2nd ed Philadelphia, PA Elsevier/Saunders
    • Mann DL, Mann DL, Activation of inflammatory mediators in heart failure. In: Heart failure: A Companion to Braunwald's Heart Disease 2011 2nd ed Philadelphia, PA Elsevier/Saunders 163 184
    • (2011) Heart Failure: A Companion to Braunwald's Heart Disease , pp. 163-184
    • Mann, D.L.1    Mann, D.L.2
  • 55
    • 0028986977 scopus 로고
    • Cytokine-binding proteins: Stimulating antagonists
    • Klein B, Brailly H, Cytokine-binding proteins: stimulating antagonists. Immunol Today 1995; 16: 216-220. doi: 10.1016/0167-5699(95)80161-8.
    • (1995) Immunol Today , vol.16 , pp. 216-220
    • Klein, B.1    Brailly, H.2
  • 56
    • 0034989568 scopus 로고    scopus 로고
    • Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure
    • Packer M, Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure. J Card Fail 2001; 7: 176-182. doi: 10.1054/jcaf.2001.25652.
    • (2001) J Card Fail , vol.7 , pp. 176-182
    • Packer, M.1
  • 57
    • 0028269337 scopus 로고
    • Complement activation and inhibition in myocardial ischemia and reperfusion injury
    • Homeister JW, Lucchesi BR, Complement activation and inhibition in myocardial ischemia and reperfusion injury. Annu Rev Pharmacol Toxicol 1994; 34: 17-40. doi: 10.1146/annurev.pa.34.040194.000313.
    • (1994) Annu Rev Pharmacol Toxicol , vol.34 , pp. 17-40
    • Homeister, J.W.1    Lucchesi, B.R.2
  • 58
    • 0037672879 scopus 로고    scopus 로고
    • Case reports of heart failure after therapy with a tumor necrosis factor antagonist
    • Kwon HJ, Coté TR, Cuffe MS, Kramer JM, Braun MM, Case reports of heart failure after therapy with a tumor necrosis factor antagonist. Ann Intern Med 2003 138 807 811
    • (2003) Ann Intern Med , vol.138 , pp. 807-811
    • Kwon, H.J.1    Coté, T.R.2    Cuffe, M.S.3    Kramer, J.M.4    Braun, M.M.5
  • 59
    • 1242315583 scopus 로고    scopus 로고
    • Heart failure in rheumatoid arthritis: Rates, predictors, and the effect of anti-tumor necrosis factor therapy
    • Wolfe F, Michaud K, Heart failure in rheumatoid arthritis: rates, predictors, and the effect of anti-tumor necrosis factor therapy. Am J Med 2004; 116: 305-311. doi: 10.1016/j.amjmed.2003.09.039.
    • (2004) Am J Med , vol.116 , pp. 305-311
    • Wolfe, F.1    Michaud, K.2
  • 62
    • 84859832981 scopus 로고    scopus 로고
    • 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis
    • Singh JA, Furst DE, Bharat A, 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012; 64: 625-639. doi: 10.1002/acr.21641.
    • (2012) Arthritis Care Res (Hoboken) , vol.64 , pp. 625-639
    • Singh, J.A.1    Furst, D.E.2    Bharat, A.3
  • 63
    • 82155192578 scopus 로고    scopus 로고
    • Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse
    • Abbate A, Salloum FN, Van Tassell BW, Vecile E, Toldo S, Seropian I, Mezzaroma E, Dobrina A, Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse. PLoS One 2011 6 e27923. doi: 10.1371/journal.pone.0027923.
    • (2011) PLoS One , vol.6 , pp. e27923
    • Abbate, A.1    Salloum, F.N.2    Van Tassell, B.W.3    Vecile, E.4    Toldo, S.5    Seropian, I.6    Mezzaroma, E.7    Dobrina, A.8
  • 64
    • 84876981024 scopus 로고    scopus 로고
    • Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study]
    • Abbate A, Van Tassell BW, Biondi-Zoccai G, Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study]. Am J Cardiol 2013; 111: 1394-1400. doi: 10.1016/j.amjcard.2013.01.287.
    • (2013) Am J Cardiol , vol.111 , pp. 1394-1400
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.3
  • 67
    • 38349150595 scopus 로고    scopus 로고
    • Experimental and clinical basis for the use of statins in patients with ischemic and nonischemic cardiomyopathy
    • Ramasubbu K, Estep J, White DL, Deswal A, Mann DL, Experimental and clinical basis for the use of statins in patients with ischemic and nonischemic cardiomyopathy. J Am Coll Cardiol 2008; 51: 415-426. doi: 10.1016/j.jacc.2007.10.009.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 415-426
    • Ramasubbu, K.1    Estep, J.2    White, D.L.3    Deswal, A.4    Mann, D.L.5
  • 68
    • 70349493143 scopus 로고    scopus 로고
    • Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): A retrospective analysis
    • McMurray JJ, Kjekshus J, Gullestad L, CORONA Study Group Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis. Circulation 2009; 120: 2188-2196. doi: 10.1161/CIRCULATIONAHA.109.849117.
    • (2009) Circulation , vol.120 , pp. 2188-2196
    • McMurray, J.J.1    Kjekshus, J.2    Gullestad, L.3
  • 69
    • 84885842429 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
    • Yancy CW, Jessup M, Bozkurt B, 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation 2013; 128: 1810-1852. doi: 10.1161/CIR.0b013e31829e8807.
    • (2013) Circulation , vol.128 , pp. 1810-1852
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 70
    • 0037461111 scopus 로고    scopus 로고
    • Uric acid and survival in chronic heart failure: Validation and application in metabolic, functional, and hemodynamic staging
    • Anker SD, Doehner W, Rauchhaus M, Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging. Circulation 2003; 107: 1991-1997. doi: 10.1161/01.CIR.0000065637.10517.A0.
    • (2003) Circulation , vol.107 , pp. 1991-1997
    • Anker, S.D.1    Doehner, W.2    Rauchhaus, M.3
  • 71
    • 79957526145 scopus 로고    scopus 로고
    • The role of uric acid as an endogenous danger signal in immunity and inflammation
    • Ghaemi-Oskouie F, Shi Y, The role of uric acid as an endogenous danger signal in immunity and inflammation. Curr Rheumatol Rep 2011; 13: 160-166. doi: 10.1007/s11926-011-0162-1.
    • (2011) Curr Rheumatol Rep , vol.13 , pp. 160-166
    • Ghaemi-Oskouie, F.1    Shi, Y.2
  • 72
    • 84897109919 scopus 로고    scopus 로고
    • Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure: Critical importance of the cardiosplenic axis
    • Ismahil MA, Hamid T, Bansal SS, Patel B, Kingery JR, Prabhu SD, Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure: critical importance of the cardiosplenic axis. Circ Res 2014; 114: 266-282. doi: 10.1161/CIRCRESAHA.113.301720.
    • (2014) Circ Res , vol.114 , pp. 266-282
    • Ismahil, M.A.1    Hamid, T.2    Bansal, S.S.3    Patel, B.4    Kingery, J.R.5    Prabhu, S.D.6
  • 73
    • 84859432016 scopus 로고    scopus 로고
    • Activation of CD4+ T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice
    • Hofmann U, Beyersdorf N, Weirather J, Podolskaya A, Bauersachs J, Ertl G, Kerkau T, Frantz S, Activation of CD4+ T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice. Circulation 2012; 125: 1652-1663. doi: 10.1161/CIRCULATIONAHA.111.044164.
    • (2012) Circulation , vol.125 , pp. 1652-1663
    • Hofmann, U.1    Beyersdorf, N.2    Weirather, J.3    Podolskaya, A.4    Bauersachs, J.5    Ertl, G.6    Kerkau, T.7    Frantz, S.8
  • 74
    • 84892450644 scopus 로고    scopus 로고
    • Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation
    • Epelman S, Lavine KJ, Beaudin AE, Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 2014; 40: 91-104. doi: 10.1016/j.immuni.2013.11.019.
    • (2014) Immunity , vol.40 , pp. 91-104
    • Epelman, S.1    Lavine, K.J.2    Beaudin, A.E.3
  • 76
    • 26844451781 scopus 로고    scopus 로고
    • How much of the increased incidence of heart failure in rheumatoid arthritis is attributable to traditional cardiovascular risk factors and ischemic heart disease?
    • Crowson CS, Nicola PJ, Kremers HM, O'Fallon WM, Therneau TM, Jacobsen SJ, Roger VL, Ballman KV, Gabriel SE, How much of the increased incidence of heart failure in rheumatoid arthritis is attributable to traditional cardiovascular risk factors and ischemic heart disease? Arthritis Rheum 2005; 52: 3039-3044. doi: 10.1002/art.21349.
    • (2005) Arthritis Rheum , vol.52 , pp. 3039-3044
    • Crowson, C.S.1    Nicola, P.J.2    Kremers, H.M.3    O'Fallon, W.M.4    Therneau, T.M.5    Jacobsen, S.J.6    Roger, V.L.7    Ballman, K.V.8    Gabriel, S.E.9
  • 77
    • 47849128962 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis
    • Setoguchi S, Schneeweiss S, Avorn J, Katz JN, Weinblatt ME, Levin R, Solomon DH, Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis. Am Heart J 2008; 156: 336-341. doi: 10.1016/j.ahj.2008.02.025.
    • (2008) Am Heart J , vol.156 , pp. 336-341
    • Setoguchi, S.1    Schneeweiss, S.2    Avorn, J.3    Katz, J.N.4    Weinblatt, M.E.5    Levin, R.6    Solomon, D.H.7
  • 78
    • 29144481887 scopus 로고    scopus 로고
    • The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure
    • Gong K, Zhang Z, Sun X, Zhang X, Li A, Yan J, Luo Q, Gao Y, Feng Y, The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure. Am Heart J 2006; 151: 62-68. doi: 10.1016/j.ahj.2005.02.040.
    • (2006) Am Heart J , vol.151 , pp. 62-68
    • Gong, K.1    Zhang, Z.2    Sun, X.3    Zhang, X.4    Li, A.5    Yan, J.6    Luo, Q.7    Gao, Y.8    Feng, Y.9
  • 79
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM, Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 1998; 101: 890-898. doi: 10.1172/JCI1112.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 81
    • 4444269967 scopus 로고    scopus 로고
    • Effects of a novel immune modulation therapy in patients with advanced chronic heart failure: Results of a randomized, controlled, phase II trial
    • Torre-Amione G, Sestier F, Radovancevic B, Young J, Effects of a novel immune modulation therapy in patients with advanced chronic heart failure: results of a randomized, controlled, phase II trial. J Am Coll Cardiol 2004; 44: 1181-1186. doi: 10.1016/j.jacc.2004.06.047.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1181-1186
    • Torre-Amione, G.1    Sestier, F.2    Radovancevic, B.3    Young, J.4
  • 83
    • 84855371938 scopus 로고    scopus 로고
    • Autoantibodies in heart failure and cardiac dysfunction
    • Kaya Z, Leib C, Katus HA, Autoantibodies in heart failure and cardiac dysfunction. Circ Res 2012; 110: 145-158. doi: 10.1161/CIRCRESAHA.111.243360.
    • (2012) Circ Res , vol.110 , pp. 145-158
    • Kaya, Z.1    Leib, C.2    Katus, H.A.3
  • 84
    • 0035053668 scopus 로고    scopus 로고
    • Infection, mimics, and autoimmune disease
    • Rose NR, Infection, mimics, and autoimmune disease. J Clin Invest 2001; 107: 943-944. doi: 10.1172/JCI12673.
    • (2001) J Clin Invest , vol.107 , pp. 943-944
    • Rose, N.R.1
  • 85
    • 0034964392 scopus 로고    scopus 로고
    • Autoimmunity, immunoglobulin adsorption and dilated cardiomyopathy: Has the time come for randomized clinical trials?
    • Mann DL, Autoimmunity, immunoglobulin adsorption and dilated cardiomyopathy: has the time come for randomized clinical trials? J Am Coll Cardiol 2001 38 184 186
    • (2001) J Am Coll Cardiol , vol.38 , pp. 184-186
    • Mann, D.L.1
  • 86
    • 2942532947 scopus 로고    scopus 로고
    • Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy
    • Jahns R, Boivin V, Hein L, Triebel S, Angermann CE, Ertl G, Lohse MJ, Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy. J Clin Invest 2004; 113: 1419-1429. doi: 10.1172/JCI20149.
    • (2004) J Clin Invest , vol.113 , pp. 1419-1429
    • Jahns, R.1    Boivin, V.2    Hein, L.3    Triebel, S.4    Angermann, C.E.5    Ertl, G.6    Lohse, M.J.7
  • 87
    • 84867716776 scopus 로고    scopus 로고
    • Administration of the cyclic peptide COR-1 in humans (phase i study): Ex vivo measurements of anti-β1-adrenergic receptor antibody neutralization and of immune parameters
    • Münch G, Boivin-Jahns V, Holthoff HP, Adler K, Lappo M, Truöl S, Degen H, Steiger N, Lohse MJ, Jahns R, Ungerer M, Administration of the cyclic peptide COR-1 in humans (phase I study): ex vivo measurements of anti-β1-adrenergic receptor antibody neutralization and of immune parameters. Eur J Heart Fail 2012; 14: 1230-1239. doi: 10.1093/eurjhf/hfs118.
    • (2012) Eur J Heart Fail , vol.14 , pp. 1230-1239
    • Münch, G.1    Boivin-Jahns, V.2    Holthoff, H.P.3    Adler, K.4    Lappo, M.5    Truöl, S.6    Degen, H.7    Steiger, N.8    Lohse, M.J.9    Jahns, R.10    Ungerer, M.11
  • 88
    • 84891755468 scopus 로고    scopus 로고
    • TLR2 and TLR4 in autoimmune diseases: A comprehensive review
    • Liu Y, Yin H, Zhao M, Lu Q, TLR2 and TLR4 in autoimmune diseases: a comprehensive review. Clin Rev Allergy Immunol 2014; 47: 136-147. doi: 10.1007/s12016-013-8402-y.
    • (2014) Clin Rev Allergy Immunol , vol.47 , pp. 136-147
    • Liu, Y.1    Yin, H.2    Zhao, M.3    Lu, Q.4
  • 89
    • 0030268577 scopus 로고    scopus 로고
    • Surrogate end points in clinical trials: Are we being misled?
    • Fleming TR, DeMets DL, Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996 125 605 613
    • (1996) Ann Intern Med , vol.125 , pp. 605-613
    • Fleming, T.R.1    DeMets, D.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.