메뉴 건너뛰기




Volumn 8, Issue MAR, 2017, Pages

Type I interferons as regulators of lung inflammation

Author keywords

Infection; Inflammation; Lung; Pattern recognition receptors; Type I interferons

Indexed keywords

INTERFERON; INTERFERON RECEPTOR; PATHOGEN ASSOCIATED MOLECULAR PATTERN; PATTERN RECOGNITION RECEPTOR;

EID: 85017236177     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00259     Document Type: Review
Times cited : (125)

References (113)
  • 1
    • 84925283050 scopus 로고    scopus 로고
    • The development and function of lung-resident macrophages and dendritic cells
    • Kopf M, Schneider C, Nobs SP. The development and function of lung-resident macrophages and dendritic cells. Nat Immunol (2014) 16:36-44. doi:10.1038/ni.3052
    • (2014) Nat Immunol , vol.16 , pp. 36-44
    • Kopf, M.1    Schneider, C.2    Nobs, S.P.3
  • 2
    • 84881658991 scopus 로고    scopus 로고
    • Interferon induction and function at the mucosal surface
    • Durbin RK, Kotenko SV, Durbin JE. Interferon induction and function at the mucosal surface. Immunol Rev (2013) 255:25-39. doi:10.1111/imr.12101
    • (2013) Immunol Rev , vol.255 , pp. 25-39
    • Durbin, R.K.1    Kotenko, S.V.2    Durbin, J.E.3
  • 4
    • 82955233182 scopus 로고    scopus 로고
    • Type I interferons: diversity of sources, production pathways and effects on immune responses
    • Swiecki M, Colonna M. Type I interferons: diversity of sources, production pathways and effects on immune responses. Curr Opin Virol (2011) 1:463-75. doi:10.1016/j.coviro.2011.10.026
    • (2011) Curr Opin Virol , vol.1 , pp. 463-475
    • Swiecki, M.1    Colonna, M.2
  • 5
    • 84937779845 scopus 로고    scopus 로고
    • Guarding the frontiers: the biology of type III interferons
    • Wack A, Terczynska-Dyla E, Hartmann R. Guarding the frontiers: the biology of type III interferons. Nat Immunol (2015) 16:802-9. doi:10.1038/ni.3212
    • (2015) Nat Immunol , vol.16 , pp. 802-809
    • Wack, A.1    Terczynska-Dyla, E.2    Hartmann, R.3
  • 6
    • 84919663450 scopus 로고    scopus 로고
    • IL-28B is a key regulator of B-and T-cell vaccine responses against influenza
    • Egli A, Santer DM, O'Shea D, Barakat K, Syedbasha M, Vollmer M, et al. IL-28B is a key regulator of B-and T-cell vaccine responses against influenza. PLoS Pathog (2014) 10:e1004556. doi:10.1371/journal.ppat.1004556
    • (2014) PLoS Pathog , vol.10
    • Egli, A.1    Santer, D.M.2    O'Shea, D.3    Barakat, K.4    Syedbasha, M.5    Vollmer, M.6
  • 7
    • 84873083416 scopus 로고    scopus 로고
    • A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
    • Prokunina-Olsson L, Muchmore B, Tang W, Pfeiffer RM, Park H, Dickensheets H, et al. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat Genet (2013) 45:164-71. doi:10.1038/ng.2521
    • (2013) Nat Genet , vol.45 , pp. 164-171
    • Prokunina-Olsson, L.1    Muchmore, B.2    Tang, W.3    Pfeiffer, R.M.4    Park, H.5    Dickensheets, H.6
  • 9
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity (2011) 34:637-50. doi:10.1016/j.immuni.2011.05.006
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 10
    • 79956314622 scopus 로고    scopus 로고
    • Immune signaling by RIG-I-like receptors
    • Loo Y-M, Gale M. Immune signaling by RIG-I-like receptors. Immunity (2011) 34:680-92. doi:10.1016/j.immuni.2011.05.003
    • (2011) Immunity , vol.34 , pp. 680-692
    • Loo, Y.-M.1    Gale, M.2
  • 11
    • 84878173821 scopus 로고    scopus 로고
    • Cytosolic sensing of viruses
    • Goubau D, Deddouche S, Reis e Sousa C. Cytosolic sensing of viruses. Immunity (2013) 38:855-69. doi:10.1016/j.immuni.2013.05.007
    • (2013) Immunity , vol.38 , pp. 855-869
    • Goubau, D.1    Deddouche, S.2    Reis e Sousa, C.3
  • 12
    • 84927639135 scopus 로고    scopus 로고
    • Innate immune pattern recognition: a cell biological perspective
    • Brubaker SW, Bonham KS, Zanoni I, Kagan JC. Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol (2015) 33:257-90. doi:10.1146/annurev-immunol-032414-112240
    • (2015) Annu Rev Immunol , vol.33 , pp. 257-290
    • Brubaker, S.W.1    Bonham, K.S.2    Zanoni, I.3    Kagan, J.C.4
  • 13
    • 84881027832 scopus 로고    scopus 로고
    • Innate immune detection of microbial nucleic acids
    • Gürtler C, Bowie AG. Innate immune detection of microbial nucleic acids. Trends Microbiol (2013) 21:413-20. doi:10.1016/j.tim.2013.04.004
    • (2013) Trends Microbiol , vol.21 , pp. 413-420
    • Gürtler, C.1    Bowie, A.G.2
  • 14
    • 84878232476 scopus 로고    scopus 로고
    • The history of toll-like receptors-redefining innate immunity
    • O'Neill LAJ, Golenbock D, Bowie AG. The history of toll-like receptors-redefining innate immunity. Nat Rev Immunol (2013) 13:453-60. doi:10.1038/nri3446
    • (2013) Nat Rev Immunol , vol.13 , pp. 453-460
    • O'Neill, L.A.J.1    Golenbock, D.2    Bowie, A.G.3
  • 15
    • 0141959224 scopus 로고    scopus 로고
    • LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
    • Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, et al. LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. J Exp Med (2003) 198:1043-55. doi:10.1084/jem.20031023
    • (2003) J Exp Med , vol.198 , pp. 1043-1055
    • Fitzgerald, K.A.1    Rowe, D.C.2    Barnes, B.J.3    Caffrey, D.R.4    Visintin, A.5    Latz, E.6
  • 16
    • 5944261457 scopus 로고    scopus 로고
    • Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
    • Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol (2000) 1:398-401. doi:10.1038/80833
    • (2000) Nat Immunol , vol.1 , pp. 398-401
    • Kurt-Jones, E.A.1    Popova, L.2    Kwinn, L.3    Haynes, L.M.4    Jones, L.P.5    Tripp, R.A.6
  • 17
    • 84908192059 scopus 로고    scopus 로고
    • Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates
    • Goubau D, Schlee M, Deddouche S, Pruijssers AJ, Zillinger T, Goldeck M, et al. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates. Nature (2014) 514:372-5. doi:10.1038/nature13590
    • (2014) Nature , vol.514 , pp. 372-375
    • Goubau, D.1    Schlee, M.2    Deddouche, S.3    Pruijssers, A.J.4    Zillinger, T.5    Goldeck, M.6
  • 19
    • 33750984771 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
    • Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, Weber F, et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science (2006) 314:997-1001. doi:10.1126/science.1132998
    • (2006) Science , vol.314 , pp. 997-1001
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Näslund, T.I.4    Liljeström, P.5    Weber, F.6
  • 20
    • 84926104091 scopus 로고    scopus 로고
    • The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly
    • Bruns AM, Leser GP, Lamb RA, Horvath CM. The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly. Mol Cell (2014) 55:771-81. doi:10.1016/j.molcel.2014.07.003
    • (2014) Mol Cell , vol.55 , pp. 771-781
    • Bruns, A.M.1    Leser, G.P.2    Lamb, R.A.3    Horvath, C.M.4
  • 21
    • 84924778328 scopus 로고    scopus 로고
    • Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
    • Liu S, Cai X, Wu J, Cong Q, Chen X, Li T, et al. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation. Science (2015) 347(6227):aaa2630. doi:10.1126/science.aaa2630
    • (2015) Science , vol.347 , Issue.6227
    • Liu, S.1    Cai, X.2    Wu, J.3    Cong, Q.4    Chen, X.5    Li, T.6
  • 22
    • 84930934680 scopus 로고    scopus 로고
    • How RIG-I like receptors activate MAVS
    • Wu B, Hur S. How RIG-I like receptors activate MAVS. Curr Opin Virol (2015) 12:91-8. doi:10.1016/j.coviro.2015.04.004
    • (2015) Curr Opin Virol , vol.12 , pp. 91-98
    • Wu, B.1    Hur, S.2
  • 23
    • 38949093002 scopus 로고    scopus 로고
    • TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
    • Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature (2008) 451:725-9. doi:10.1038/nature06537
    • (2008) Nature , vol.451 , pp. 725-729
    • Ishii, K.J.1    Kawagoe, T.2    Koyama, S.3    Matsui, K.4    Kumar, H.5    Kawai, T.6
  • 24
    • 84878190840 scopus 로고    scopus 로고
    • Immune sensing of DNA
    • Paludan SR, Bowie AG. Immune sensing of DNA. Immunity (2013) 38:870-80. doi:10.1016/j.immuni.2013.05.004
    • (2013) Immunity , vol.38 , pp. 870-880
    • Paludan, S.R.1    Bowie, A.G.2
  • 25
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
    • Chiu Y-H, Macmillan JB, Chen ZJ. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell (2009) 138:576-91. doi:10.1016/j.cell.2009.06.015
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.-H.1    Macmillan, J.B.2    Chen, Z.J.3
  • 26
    • 84953264904 scopus 로고    scopus 로고
    • Cutting edge: DNA in the lung microenvironment during influenza virus infection tempers inflammation by engaging the DNA sensor AIM2
    • Schattgen SA, Gao G, Kurt-Jones EA, Fitzgerald KA. Cutting edge: DNA in the lung microenvironment during influenza virus infection tempers inflammation by engaging the DNA sensor AIM2. J Immunol (2016) 196:29-33. doi:10.4049/jimmunol.1501048
    • (2016) J Immunol , vol.196 , pp. 29-33
    • Schattgen, S.A.1    Gao, G.2    Kurt-Jones, E.A.3    Fitzgerald, K.A.4
  • 27
    • 84857937262 scopus 로고    scopus 로고
    • STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
    • Tanaka Y, Chen ZJ. STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway. Sci Signal (2012) 5:ra20. doi:10.1126/scisignal.2002521
    • (2012) Sci Signal , vol.5
    • Tanaka, Y.1    Chen, Z.J.2
  • 28
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science (2013) 339:786-91. doi:10.1126/science.1232458
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 29
    • 84879385334 scopus 로고    scopus 로고
    • cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING
    • Ablasser A, Goldeck M, Cavlar T, Deimling T, Witte G, Röhl I, et al. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature (2013) 498:380-4. doi:10.1038/nature12306
    • (2013) Nature , vol.498 , pp. 380-384
    • Ablasser, A.1    Goldeck, M.2    Cavlar, T.3    Deimling, T.4    Witte, G.5    Röhl, I.6
  • 30
    • 84873724533 scopus 로고    scopus 로고
    • Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
    • Wu J, Sun L, Chen X, Du F, Shi H, Chen C, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science (2013) 339:826-30. doi:10.1126/science.1229963
    • (2013) Science , vol.339 , pp. 826-830
    • Wu, J.1    Sun, L.2    Chen, X.3    Du, F.4    Shi, H.5    Chen, C.6
  • 31
    • 84888637695 scopus 로고    scopus 로고
    • Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
    • Ablasser A, Schmid-Burgk JL, Hemmerling I, Horvath GL, Schmidt T, Latz E, et al. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature (2013) 503:530-4. doi:10.1038/nature12640
    • (2013) Nature , vol.503 , pp. 530-534
    • Ablasser, A.1    Schmid-Burgk, J.L.2    Hemmerling, I.3    Horvath, G.L.4    Schmidt, T.5    Latz, E.6
  • 32
    • 84888241256 scopus 로고    scopus 로고
    • Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia
    • Crotta S, Davidson S, Mahlakoiv T, Desmet CJ, Buckwalter MR, Albert ML, et al. Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia. PLoS Pathog (2013) 9:e1003773. doi:10.1371/journal.ppat.1003773
    • (2013) PLoS Pathog , vol.9
    • Crotta, S.1    Davidson, S.2    Mahlakoiv, T.3    Desmet, C.J.4    Buckwalter, M.R.5    Albert, M.L.6
  • 33
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol (2010) 11:373-84. doi:10.1038/ni.1863
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 34
    • 84899503850 scopus 로고    scopus 로고
    • Innate immunity to influenza virus infection
    • Iwasaki A, Pillai PS. Innate immunity to influenza virus infection. Nat Rev Immunol (2014) 14:315-28. doi:10.1038/nri3665
    • (2014) Nat Rev Immunol , vol.14 , pp. 315-328
    • Iwasaki, A.1    Pillai, P.S.2
  • 35
    • 84937583336 scopus 로고    scopus 로고
    • Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes
    • Goritzka M, Makris S, Kausar F, Durant LR, Pereira C, Kumagai Y, et al. Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes. J Exp Med (2015) 212:699-714. doi:10.1084/jem.20140825
    • (2015) J Exp Med , vol.212 , pp. 699-714
    • Goritzka, M.1    Makris, S.2    Kausar, F.3    Durant, L.R.4    Pereira, C.5    Kumagai, Y.6
  • 36
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I-and type-II-interferon-mediated signalling
    • Platanias LC. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat Rev Immunol (2005) 5:375-86. doi:10.1038/nri1604
    • (2005) Nat Rev Immunol , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 37
    • 79955542915 scopus 로고    scopus 로고
    • A diverse range of gene products are effectors of the type I interferon antiviral response
    • Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, et al. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature (2011) 472:481-5. doi:10.1038/nature09907
    • (2011) Nature , vol.472 , pp. 481-485
    • Schoggins, J.W.1    Wilson, S.J.2    Panis, M.3    Murphy, M.Y.4    Jones, C.T.5    Bieniasz, P.6
  • 38
    • 84898728217 scopus 로고    scopus 로고
    • Interferon-stimulated genes: roles in viral pathogenesis
    • Schoggins JW. Interferon-stimulated genes: roles in viral pathogenesis. Curr Opin Virol (2014) 6:40-6. doi:10.1016/j.coviro.2014.03.006
    • (2014) Curr Opin Virol , vol.6 , pp. 40-46
    • Schoggins, J.W.1
  • 39
    • 84859992161 scopus 로고    scopus 로고
    • The JAK-STAT pathway at twenty
    • Stark GR, Darnell JE. The JAK-STAT pathway at twenty. Immunity (2012) 36:503-14. doi:10.1016/j.immuni.2012.03.013
    • (2012) Immunity , vol.36 , pp. 503-514
    • Stark, G.R.1    Darnell, J.E.2
  • 40
    • 84896987305 scopus 로고    scopus 로고
    • Interferon-stimulated genes: a complex web of host defenses
    • Schneider WM, Chevillotte MD, Rice CM. Interferon-stimulated genes: a complex web of host defenses. Annu Rev Immunol (2014) 32:513-45. doi:10.1146/annurev-immunol-032713-120231
    • (2014) Annu Rev Immunol , vol.32 , pp. 513-545
    • Schneider, W.M.1    Chevillotte, M.D.2    Rice, C.M.3
  • 41
    • 80051983083 scopus 로고    scopus 로고
    • Structural linkage between ligand discrimination and receptor activation by type I interferons
    • Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, et al. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell (2011) 146:621-32. doi:10.1016/j.cell.2011.06.048
    • (2011) Cell , vol.146 , pp. 621-632
    • Thomas, C.1    Moraga, I.2    Levin, D.3    Krutzik, P.O.4    Podoplelova, Y.5    Trejo, A.6
  • 42
    • 84883146392 scopus 로고    scopus 로고
    • Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
    • De Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff S-J, et al. Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1. Nat Immunol (2013) 14:901-7. doi:10.1038/ni.2667
    • (2013) Nat Immunol , vol.14 , pp. 901-907
    • De Weerd, N.A.1    Vivian, J.P.2    Nguyen, T.K.3    Mangan, N.E.4    Gould, J.A.5    Braniff, S.-J.6
  • 43
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature (2005) 434:772-7. doi:10.1038/nature03464
    • (2005) Nature , vol.434 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5    Mizutani, T.6
  • 44
    • 0032538891 scopus 로고    scopus 로고
    • Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
    • Marié I, Durbin JE, Levy DE. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J (1998) 17:6660-9. doi:10.1093/emboj/17.22.6660
    • (1998) EMBO J , vol.17 , pp. 6660-6669
    • Marié, I.1    Durbin, J.E.2    Levy, D.E.3
  • 45
    • 84893075305 scopus 로고    scopus 로고
    • Regulation of type I interferon responses
    • Ivashkiv LB, Donlin LT. Regulation of type I interferon responses. Nat Rev Immunol (2013) 14:36-49. doi:10.1038/nri3581
    • (2013) Nat Rev Immunol , vol.14 , pp. 36-49
    • Ivashkiv, L.B.1    Donlin, L.T.2
  • 47
    • 55149102403 scopus 로고    scopus 로고
    • Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense
    • Zhang S-Y, Boisson-Dupuis S, Chapgier A, Yang K, Bustamante J, Puel A, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev (2008) 226:29-40. doi:10.1111/j.1600-065X.2008.00698.x
    • (2008) Immunol Rev , vol.226 , pp. 29-40
    • Zhang, S.-Y.1    Boisson-Dupuis, S.2    Chapgier, A.3    Yang, K.4    Bustamante, J.5    Puel, A.6
  • 48
    • 84928377935 scopus 로고    scopus 로고
    • Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency
    • Ciancanelli MJ, Huang SXL, Luthra P, Garner H, Itan Y, Volpi S, et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science (2015) 348:448-53. doi:10.1126/science.aaa1578
    • (2015) Science , vol.348 , pp. 448-453
    • Ciancanelli, M.J.1    Huang, S.X.L.2    Luthra, P.3    Garner, H.4    Itan, Y.5    Volpi, S.6
  • 49
    • 34548475750 scopus 로고    scopus 로고
    • Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes
    • Janssen R, Bont L, Siezen CLE, Hodemaekers HM, Ermers MJ, Doornbos G, et al. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. J Infect Dis (2007) 196:826-34. doi:10.1086/520886
    • (2007) J Infect Dis , vol.196 , pp. 826-834
    • Janssen, R.1    Bont, L.2    Siezen, C.L.E.3    Hodemaekers, H.M.4    Ermers, M.J.5    Doornbos, G.6
  • 50
    • 65649136910 scopus 로고    scopus 로고
    • Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes
    • Siezen CLE, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, et al. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Pediatr Infect Dis J (2009) 28:333-5. doi:10.1097/INF.0b013e31818e2aa9
    • (2009) Pediatr Infect Dis J , vol.28 , pp. 333-335
    • Siezen, C.L.E.1    Bont, L.2    Hodemaekers, H.M.3    Ermers, M.J.4    Doornbos, G.5    Van't Slot, R.6
  • 51
    • 84862777209 scopus 로고    scopus 로고
    • IFITM3 restricts the morbidity and mortality associated with influenza
    • Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 484:519-23. doi:10.1038/nature10921
    • (2012) Nature , vol.484 , pp. 519-523
    • Everitt, A.R.1    Clare, S.2    Pertel, T.3    John, S.P.4    Wash, R.S.5    Smith, S.E.6
  • 52
    • 84876377407 scopus 로고    scopus 로고
    • Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals
    • Zhang Y-H, Zhao Y, Li N, Peng Y-C, Giannoulatou E, Jin R-H, et al. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals. Nat Commun (2013) 4:1418. doi:10.1038/ncomms2433
    • (2013) Nat Commun , vol.4 , pp. 1418
    • Zhang, Y.-H.1    Zhao, Y.2    Li, N.3    Peng, Y.-C.4    Giannoulatou, E.5    Jin, R.-H.6
  • 53
    • 84964798222 scopus 로고    scopus 로고
    • Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease
    • Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science (2016) 352:463-6. doi:10.1126/science.aaf3926
    • (2016) Science , vol.352 , pp. 463-466
    • Pillai, P.S.1    Molony, R.D.2    Martinod, K.3    Dong, H.4    Pang, I.K.5    Tal, M.C.6
  • 54
    • 84952884939 scopus 로고    scopus 로고
    • Host genetics of severe influenza: from mouse Mx1 to human IRF7
    • Ciancanelli MJ, Abel L, Zhang S-Y, Casanova J-L. Host genetics of severe influenza: from mouse Mx1 to human IRF7. Curr Opin Immunol (2016) 38:109-20. doi:10.1016/j.coi.2015.12.002
    • (2016) Curr Opin Immunol , vol.38 , pp. 109-120
    • Ciancanelli, M.J.1    Abel, L.2    Zhang, S.-Y.3    Casanova, J.-L.4
  • 55
    • 77957745555 scopus 로고    scopus 로고
    • Type I interferon: friend or foe
    • Trinchieri G. Type I interferon: friend or foe? J Exp Med (2010) 207:2053-63. doi:10.1084/jem.20101664
    • (2010) J Exp Med , vol.207 , pp. 2053-2063
    • Trinchieri, G.1
  • 56
    • 84899829425 scopus 로고    scopus 로고
    • Interferon-α/β receptor signaling amplifies early pro-inflammatory cytokine production in the lung during respiratory syncytial virus infection
    • Goritzka M, Durant LR, Pereira C, Salek-Ardakani S, Openshaw PJM, Johansson C. Interferon-α/β receptor signaling amplifies early pro-inflammatory cytokine production in the lung during respiratory syncytial virus infection. J Virol (2014) 88:6128-36. doi:10.1128/JVI.00333-14
    • (2014) J Virol , vol.88 , pp. 6128-6136
    • Goritzka, M.1    Durant, L.R.2    Pereira, C.3    Salek-Ardakani, S.4    Openshaw, P.J.M.5    Johansson, C.6
  • 57
    • 84971376324 scopus 로고    scopus 로고
    • CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection
    • Lehmann MH, Torres-Domínguez LE, Price PJR, Brandmüller C, Kirschning CJ, Sutter G. CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection. J Leukoc Biol (2016) 99:1057-64. doi:10.1189/jlb.4MA0815-376RR
    • (2016) J Leukoc Biol , vol.99 , pp. 1057-1064
    • Lehmann, M.H.1    Torres-Domínguez, L.E.2    Price, P.J.R.3    Brandmüller, C.4    Kirschning, C.J.5    Sutter, G.6
  • 58
    • 33748455338 scopus 로고    scopus 로고
    • Type I interferons in host defense
    • Stetson DB, Medzhitov R. Type I interferons in host defense. Immunity (2006) 25:373-81. doi:10.1016/j.immuni.2006.08.007
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 59
    • 0035284744 scopus 로고    scopus 로고
    • Differential regulation of human blood dendritic cell subsets by IFNs
    • Ito T, Amakawa R, Inaba M, Ikehara S, Inaba K, Fukuhara S. Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol (2001) 166:2961-9. doi:10.4049/jimmunol.166.5.2961
    • (2001) J Immunol , vol.166 , pp. 2961-2969
    • Ito, T.1    Amakawa, R.2    Inaba, M.3    Ikehara, S.4    Inaba, K.5    Fukuhara, S.6
  • 60
    • 0142092614 scopus 로고    scopus 로고
    • Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
    • Le Bon A, Etchart N, Rossmann C, Ashton M, Hou S, Gewert D, et al. Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon. Nat Immunol (2003) 4:1009-15. doi:10.1038/ni978
    • (2003) Nat Immunol , vol.4 , pp. 1009-1015
    • Le Bon, A.1    Etchart, N.2    Rossmann, C.3    Ashton, M.4    Hou, S.5    Gewert, D.6
  • 61
    • 79952109911 scopus 로고    scopus 로고
    • Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-a
    • Rouzaut A, Garasa S, Teijeira A, González I, Martinez-Forero I, Suarez N, et al. Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-a. Eur J Immunol (2010) 40:3054-63. doi:10.1002/eji.201040523
    • (2010) Eur J Immunol , vol.40 , pp. 3054-3063
    • Rouzaut, A.1    Garasa, S.2    Teijeira, A.3    González, I.4    Martinez-Forero, I.5    Suarez, N.6
  • 62
    • 84856884584 scopus 로고    scopus 로고
    • IFN-a enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing
    • Spadaro F, Lapenta C, Donati S, Abalsamo L, Barnaba V, Belardelli F, et al. IFN-a enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing. Blood (2012) 119:1407-17. doi:10.1182/blood-2011-06-363564
    • (2012) Blood , vol.119 , pp. 1407-1417
    • Spadaro, F.1    Lapenta, C.2    Donati, S.3    Abalsamo, L.4    Barnaba, V.5    Belardelli, F.6
  • 63
    • 84925719346 scopus 로고    scopus 로고
    • Regulation of antiviral T cell responses by type I interferons
    • Crouse J, Kalinke U, Oxenius A. Regulation of antiviral T cell responses by type I interferons. Nat Rev Immunol (2015) 15:231-42. doi:10.1038/nri3806
    • (2015) Nat Rev Immunol , vol.15 , pp. 231-242
    • Crouse, J.1    Kalinke, U.2    Oxenius, A.3
  • 64
    • 17244374001 scopus 로고    scopus 로고
    • Type I interferon dependence of plasmacytoid dendritic cell activation and migration
    • Asselin-Paturel C, Brizard G, Chemin K, Boonstra A, O'Garra A, Vicari A, et al. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med (2005) 201:1157-67. doi:10.1084/jem.20041930
    • (2005) J Exp Med , vol.201 , pp. 1157-1167
    • Asselin-Paturel, C.1    Brizard, G.2    Chemin, K.3    Boonstra, A.4    O'Garra, A.5    Vicari, A.6
  • 65
    • 67650445798 scopus 로고    scopus 로고
    • Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
    • Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, Kluger C, et al. Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med (2009) 206:1589-602. doi:10.1084/jem.20090247
    • (2009) J Exp Med , vol.206 , pp. 1589-1602
    • Longhi, M.P.1    Trumpfheller, C.2    Idoyaga, J.3    Caskey, M.4    Matos, I.5    Kluger, C.6
  • 66
    • 0141703238 scopus 로고    scopus 로고
    • Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
    • Honda K, Sakaguchi S, Nakajima C, Watanabe A, Yanai H, Matsumoto M, et al. Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc Natl Acad Sci U S A (2003) 100:10872-7. doi:10.1073/pnas.1934678100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10872-10877
    • Honda, K.1    Sakaguchi, S.2    Nakajima, C.3    Watanabe, A.4    Yanai, H.5    Matsumoto, M.6
  • 67
    • 81755187264 scopus 로고    scopus 로고
    • Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection
    • Moltedo B, Li W, Yount JS, Moran TM. Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection. PLoS Pathog (2011) 7:e1002345. doi:10.1371/journal.ppat.1002345
    • (2011) PLoS Pathog , vol.7
    • Moltedo, B.1    Li, W.2    Yount, J.S.3    Moran, T.M.4
  • 69
    • 84861709318 scopus 로고    scopus 로고
    • Modulation of T-cell function by type I interferon
    • Tough DF. Modulation of T-cell function by type I interferon. Immunol Cell Biol (2012) 90:492-7. doi:10.1038/icb.2012.7
    • (2012) Immunol Cell Biol , vol.90 , pp. 492-497
    • Tough, D.F.1
  • 70
    • 32044460431 scopus 로고    scopus 로고
    • Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
    • Le Bon A, Thompson C, Kamphuis E, Durand V, Rossmann C, Kalinke U, et al. Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J Immunol (2006) 176:2074-8. doi:10.4049/jimmunol.176.4.2074
    • (2006) J Immunol , vol.176 , pp. 2074-2078
    • Le Bon, A.1    Thompson, C.2    Kamphuis, E.3    Durand, V.4    Rossmann, C.5    Kalinke, U.6
  • 71
    • 33846526235 scopus 로고    scopus 로고
    • Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals
    • Chang WLW, Coro ES, Rau FC, Xiao Y, Erle DJ, Baumgarth N. Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals. J Immunol (2007) 178:1457-67. doi:10.4049/jimmunol.178.3.1457
    • (2007) J Immunol , vol.178 , pp. 1457-1467
    • Chang, W.L.W.1    Coro, E.S.2    Rau, F.C.3    Xiao, Y.4    Erle, D.J.5    Baumgarth, N.6
  • 72
    • 84997122944 scopus 로고    scopus 로고
    • Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation
    • Moseman EA, Wu T, la Torre de JC, Schwartzberg PL, McGavern DB. Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation. Sci Immunol (2016) 1(4). doi:10.1126/sciimmunol.aah3565
    • (2016) Sci Immunol , vol.1 , Issue.4
    • Moseman, E.A.1    Wu, T.2    la Torre de, J.C.3    Schwartzberg, P.L.4    McGavern, D.B.5
  • 73
    • 84984804780 scopus 로고    scopus 로고
    • IFN? is a potent anti-influenza therapeutic without the inflammatory side effects of IFNa treatment
    • Davidson S, McCabe TM, Crotta S, Gad HH, Hessel EM, Beinke S, et al. IFN? is a potent anti-influenza therapeutic without the inflammatory side effects of IFNa treatment. EMBO Mol Med (2016) 8:1099-112. doi:10.15252/emmm.201606413
    • (2016) EMBO Mol Med , vol.8 , pp. 1099-1112
    • Davidson, S.1    McCabe, T.M.2    Crotta, S.3    Gad, H.H.4    Hessel, E.M.5    Beinke, S.6
  • 74
    • 79960115481 scopus 로고    scopus 로고
    • The role of nuclear factor κB in the interferon response
    • Pfeffer LM. The role of nuclear factor κB in the interferon response. J Interferon Cytokine Res (2011) 31:553-9. doi:10.1089/jir.2011.0028
    • (2011) J Interferon Cytokine Res , vol.31 , pp. 553-559
    • Pfeffer, L.M.1
  • 75
    • 77956406173 scopus 로고    scopus 로고
    • Regulation of immune cell homeostasis by type I interferons
    • Mattei F, Schiavoni G, Tough DF. Regulation of immune cell homeostasis by type I interferons. Cytokine Growth Factor Rev (2010) 21:227-36. doi:10.1016/j.cytogfr.2010.05.002
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 227-236
    • Mattei, F.1    Schiavoni, G.2    Tough, D.F.3
  • 76
    • 29144501207 scopus 로고    scopus 로고
    • The interferon response circuit: induction and suppression by pathogenic viruses
    • Haller O, Kochs G, Weber F. The interferon response circuit: induction and suppression by pathogenic viruses. Virology (2006) 344:119-30. doi:10.1016/j.virol.2005.09.024
    • (2006) Virology , vol.344 , pp. 119-130
    • Haller, O.1    Kochs, G.2    Weber, F.3
  • 77
    • 35448938101 scopus 로고    scopus 로고
    • Upregulation of a small subset of genes drives type I interferon-induced antiviral memory
    • Jaitin DA, Schreiber G. Upregulation of a small subset of genes drives type I interferon-induced antiviral memory. J Interferon Cytokine Res (2007) 27:653-64. doi:10.1089/jir.2006.0162
    • (2007) J Interferon Cytokine Res , vol.27 , pp. 653-664
    • Jaitin, D.A.1    Schreiber, G.2
  • 78
    • 85012027074 scopus 로고    scopus 로고
    • Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice
    • Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, et al. Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice. Cell Host Microbe (2016) 19:181-93. doi:10.1016/j.chom.2016.01.007
    • (2016) Cell Host Microbe , vol.19 , pp. 181-193
    • Channappanavar, R.1    Fehr, A.R.2    Vijay, R.3    Mack, M.4    Zhao, J.5    Meyerholz, D.K.6
  • 79
    • 84862794613 scopus 로고    scopus 로고
    • The yin and yang of viruses and interferons
    • Wang BX, Fish EN. The yin and yang of viruses and interferons. Trends Immunol (2012) 33:190-7. doi:10.1016/j.it.2012.01.004
    • (2012) Trends Immunol , vol.33 , pp. 190-197
    • Wang, B.X.1    Fish, E.N.2
  • 80
    • 85006164562 scopus 로고    scopus 로고
    • Viral evasion strategies in type I IFN signaling-a summary of recent developments
    • Schulz KS, Mossman KL. Viral evasion strategies in type I IFN signaling-a summary of recent developments. Front Immunol (2016) 7:459. doi:10.3389/fimmu.2016.00498
    • (2016) Front Immunol , vol.7 , pp. 459
    • Schulz, K.S.1    Mossman, K.L.2
  • 81
    • 84931570382 scopus 로고    scopus 로고
    • Early IFN type I response: learning from microbial evasion strategies
    • Coccia EM, Battistini A. Early IFN type I response: learning from microbial evasion strategies. Semin Immunol (2015) 27:85-101. doi:10.1016/j.smim.2015.03.005
    • (2015) Semin Immunol , vol.27 , pp. 85-101
    • Coccia, E.M.1    Battistini, A.2
  • 82
    • 35348882688 scopus 로고    scopus 로고
    • Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo
    • Jewell NA, Vaghefi N, Mertz SE, Akter P, Peebles RS, Bakaletz LO, et al. Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo. J Virol (2007) 81:9790-800. doi:10.1128/JVI.00530-07
    • (2007) J Virol , vol.81 , pp. 9790-9800
    • Jewell, N.A.1    Vaghefi, N.2    Mertz, S.E.3    Akter, P.4    Peebles, R.S.5    Bakaletz, L.O.6
  • 83
    • 84901358668 scopus 로고    scopus 로고
    • Pathogenic potential of interferon αβ in acute influenza infection
    • Davidson S, Crotta S, McCabe TM, Wack A. Pathogenic potential of interferon αβ in acute influenza infection. Nat Commun (2014) 5:3864. doi:10.1038/ncomms4864
    • (2014) Nat Commun , vol.5 , pp. 3864
    • Davidson, S.1    Crotta, S.2    McCabe, T.M.3    Wack, A.4
  • 84
    • 84904891710 scopus 로고    scopus 로고
    • Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection
    • Cormier SA, Shrestha B, Saravia J, Lee GI, Shen L, DeVincenzo JP, et al. Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection. J Virol (2014) 88:9350-60. doi:10.1128/JVI.00818-14
    • (2014) J Virol , vol.88 , pp. 9350-9360
    • Cormier, S.A.1    Shrestha, B.2    Saravia, J.3    Lee, G.I.4    Shen, L.5    DeVincenzo, J.P.6
  • 85
    • 84962886214 scopus 로고    scopus 로고
    • Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV re-exposure in neonate mice
    • Remot A, Descamps D, Jouneau L, Laubreton D, Dubuquoy C, Bouet S, et al. Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV re-exposure in neonate mice. Eur J Immunol (2015) 46:874-84. doi:10.1002/eji.201545929
    • (2015) Eur J Immunol , vol.46 , pp. 874-884
    • Remot, A.1    Descamps, D.2    Jouneau, L.3    Laubreton, D.4    Dubuquoy, C.5    Bouet, S.6
  • 86
    • 84893365419 scopus 로고    scopus 로고
    • Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children
    • Marr N, Wang TI, Kam SHY, Hu YS, Sharma AA, Lam A, et al. Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. J Immunol (2014) 192:948-57. doi:10.4049/jimmunol.1302007
    • (2014) J Immunol , vol.192 , pp. 948-957
    • Marr, N.1    Wang, T.I.2    Kam, S.H.Y.3    Hu, Y.S.4    Sharma, A.A.5    Lam, A.6
  • 87
    • 84925427995 scopus 로고    scopus 로고
    • Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication
    • Hastings AK, Erickson JJ, Schuster JE, Boyd KL, Tollefson SJ, Johnson M, et al. Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication. J Virol (2015) 89:4405-20. doi:10.1128/JVI.03275-14
    • (2015) J Virol , vol.89 , pp. 4405-4420
    • Hastings, A.K.1    Erickson, J.J.2    Schuster, J.E.3    Boyd, K.L.4    Tollefson, S.J.5    Johnson, M.6
  • 88
    • 84951317601 scopus 로고    scopus 로고
    • Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells
    • Duerr CU, McCarthy CDA, Mindt BC, Rubio M, Meli AP, Pothlichet J, et al. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nat Immunol (2016) 17:65-75. doi:10.1038/ni.3308
    • (2016) Nat Immunol , vol.17 , pp. 65-75
    • Duerr, C.U.1    McCarthy, C.D.A.2    Mindt, B.C.3    Rubio, M.4    Meli, A.P.5    Pothlichet, J.6
  • 89
    • 0036838764 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways
    • Haeberle HA, Takizawa R, Casola A, Brasier AR, Dieterich H-J, van Rooijen N, et al. Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. J Infect Dis (2002) 186:1199-206. doi:10.1086/344644
    • (2002) J Infect Dis , vol.186 , pp. 1199-1206
    • Haeberle, H.A.1    Takizawa, R.2    Casola, A.3    Brasier, A.R.4    Dieterich, H.-J.5    van Rooijen, N.6
  • 90
    • 84956770389 scopus 로고    scopus 로고
    • Functional interplay between type I and II interferons is essential to limit influenza A virus-induced tissue inflammation
    • Stifter SA, Bhattacharyya N, Pillay R, Flórido M, Triccas JA, Britton WJ, et al. Functional interplay between type I and II interferons is essential to limit influenza A virus-induced tissue inflammation. PLoS Pathog (2016) 12:e1005378. doi:10.1371/journal.ppat.1005378
    • (2016) PLoS Pathog , vol.12
    • Stifter, S.A.1    Bhattacharyya, N.2    Pillay, R.3    Flórido, M.4    Triccas, J.A.5    Britton, W.J.6
  • 91
    • 77955290497 scopus 로고    scopus 로고
    • Antiviral instruction of bone marrow leukocytes during respiratory viral infections
    • Hermesh T, Moltedo B, Moran TM, López CB. Antiviral instruction of bone marrow leukocytes during respiratory viral infections. Cell Host Microbe (2010) 7:343-53. doi:10.1016/j.chom.2010.04.006
    • (2010) Cell Host Microbe , vol.7 , pp. 343-353
    • Hermesh, T.1    Moltedo, B.2    Moran, T.M.3    López, C.B.4
  • 92
    • 77954939630 scopus 로고    scopus 로고
    • Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge
    • Kohlmeier JE, Cookenham T, Roberts AD, Miller SC, Woodland DL. Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge. Immunity (2010) 33:96-105. doi:10.1016/j.immuni.2010.06.016
    • (2010) Immunity , vol.33 , pp. 96-105
    • Kohlmeier, J.E.1    Cookenham, T.2    Roberts, A.D.3    Miller, S.C.4    Woodland, D.L.5
  • 93
    • 85000910610 scopus 로고    scopus 로고
    • Type I IFN signaling facilitates the development of IL-10-producing effector CD8(+) T cells during murine influenza virus infection
    • Jiang L, Yao S, Huang S, Wright J, Braciale TJ, Sun J. Type I IFN signaling facilitates the development of IL-10-producing effector CD8(+) T cells during murine influenza virus infection. Eur J Immunol (2016) 46(12):2778-88. doi:10.1002/eji.201646548
    • (2016) Eur J Immunol , vol.46 , Issue.12 , pp. 2778-2788
    • Jiang, L.1    Yao, S.2    Huang, S.3    Wright, J.4    Braciale, T.J.5    Sun, J.6
  • 94
    • 84887210320 scopus 로고    scopus 로고
    • Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection
    • McNally B, Ye F, Willette M, Flaño E. Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection. J Virol (2013) 87:12916-24. doi:10.1128/JVI.02423-13
    • (2013) J Virol , vol.87 , pp. 12916-12924
    • McNally, B.1    Ye, F.2    Willette, M.3    Flaño, E.4
  • 95
    • 29644431589 scopus 로고    scopus 로고
    • Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells
    • Chaperot L, Blum A, Manches O, Lui G, Angel J, Molens J-P, et al. Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells. J Immunol (2006) 176:248-55. doi:10.4049/jimmunol.176.1.248
    • (2006) J Immunol , vol.176 , pp. 248-255
    • Chaperot, L.1    Blum, A.2    Manches, O.3    Lui, G.4    Angel, J.5    Molens, J.-P.6
  • 96
    • 59649110031 scopus 로고    scopus 로고
    • Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand
    • Herold S, Steinmueller M, Wulffen von W, Cakarova L, Pinto R, Pleschka S, et al. Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand. J Exp Med (2008) 205:3065-77. doi:10.1084/jem.20080201
    • (2008) J Exp Med , vol.205 , pp. 3065-3077
    • Herold, S.1    Steinmueller, M.2    Wulffen von, W.3    Cakarova, L.4    Pinto, R.5    Pleschka, S.6
  • 97
    • 84867317920 scopus 로고    scopus 로고
    • Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9
    • Parker D, Prince A. Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. J Immunol (2012) 189:4040-6. doi:10.4049/jimmunol.1201055
    • (2012) J Immunol , vol.189 , pp. 4040-4046
    • Parker, D.1    Prince, A.2
  • 98
    • 49649110728 scopus 로고    scopus 로고
    • Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages
    • Qiu H, Fan Y, Joyee AG, Wang S, Han X, Bai H, et al. Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J Immunol (2008) 181:2092-102. doi:10.4049/jimmunol.181.3.2092
    • (2008) J Immunol , vol.181 , pp. 2092-2102
    • Qiu, H.1    Fan, Y.2    Joyee, A.G.3    Wang, S.4    Han, X.5    Bai, H.6
  • 99
    • 84906088413 scopus 로고    scopus 로고
    • Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics
    • Dorhoi A, Yeremeev V, Nouailles G, Weiner J III, Jörg S, Heinemann E, et al. Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics. Eur J Immunol (2014) 44:2380-93. doi:10.1002/eji.201344219
    • (2014) Eur J Immunol , vol.44 , pp. 2380-2393
    • Dorhoi, A.1    Yeremeev, V.2    Nouailles, G.3    Weiner, J.4    Jörg, S.5    Heinemann, E.6
  • 100
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry MPR, Graham CM, McNab FW, Xu Z, Bloch SAA, Oni T, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature (2010) 466:973-7. doi:10.1038/nature09247
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.R.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.A.5    Oni, T.6
  • 101
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    • Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature (2014) 522:99-103. doi:10.1038/nature13489
    • (2014) Nature , vol.522 , pp. 99-103
    • Mayer-Barber, K.D.1    Andrade, B.B.2    Oland, S.D.3    Amaral, E.P.4    Barber, D.L.5    Gonzales, J.6
  • 102
    • 84906061863 scopus 로고    scopus 로고
    • Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung
    • Hughes CE, Harvey RM, Plumptre CD, Paton JC. Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung. Infect Immun (2014) 82:3919-26. doi:10.1128/IAI.02067-14
    • (2014) Infect Immun , vol.82 , pp. 3919-3926
    • Hughes, C.E.1    Harvey, R.M.2    Plumptre, C.D.3    Paton, J.C.4
  • 103
    • 84888211385 scopus 로고    scopus 로고
    • Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung
    • LeMessurier KS, Häcker H, Chi L, Tuomanen E, Redecke V. Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung. PLoS Pathog (2013) 9:e1003727. doi:10.1371/journal.ppat.1003727
    • (2013) PLoS Pathog , vol.9
    • LeMessurier, K.S.1    Häcker, H.2    Chi, L.3    Tuomanen, E.4    Redecke, V.5
  • 104
    • 84937396412 scopus 로고    scopus 로고
    • Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice
    • Lee B, Robinson KM, McHugh KJ, Scheller EV, Mandalapu S, Chen C, et al. Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice. Am J Physiol Lung Cell Mol Physiol (2015) 309:L158-67. doi:10.1152/ajplung.00338.2014
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.309 , pp. L158-L167
    • Lee, B.1    Robinson, K.M.2    McHugh, K.J.3    Scheller, E.V.4    Mandalapu, S.5    Chen, C.6
  • 105
    • 84940797003 scopus 로고    scopus 로고
    • TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection
    • Ellis GT, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection. EMBO Rep (2015) 16:1203-18. doi:10.15252/embr.201540473
    • (2015) EMBO Rep , vol.16 , pp. 1203-1218
    • Ellis, G.T.1    Davidson, S.2    Crotta, S.3    Branzk, N.4    Papayannopoulos, V.5    Wack, A.6
  • 106
    • 84869135096 scopus 로고    scopus 로고
    • Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of ?d T cells
    • Li W, Moltedo B, Moran TM. Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of ?d T cells. J Virol (2012) 86:12304-12. doi:10.1128/JVI.01269-12
    • (2012) J Virol , vol.86 , pp. 12304-12312
    • Li, W.1    Moltedo, B.2    Moran, T.M.3
  • 107
    • 68849124811 scopus 로고    scopus 로고
    • Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
    • Shahangian A, Chow EK, Tian X, Kang JR, Ghaffari A, Liu SY, et al. Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. J Clin Invest (2009) 119:1910-20. doi:10.1172/JCI35412
    • (2009) J Clin Invest , vol.119 , pp. 1910-1920
    • Shahangian, A.1    Chow, E.K.2    Tian, X.3    Kang, J.R.4    Ghaffari, A.5    Liu, S.Y.6
  • 108
    • 84923304136 scopus 로고    scopus 로고
    • The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection
    • Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B, et al. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol (2015) 16:67-74. doi:10.1038/ni.3046
    • (2015) Nat Immunol , vol.16 , pp. 67-74
    • Schliehe, C.1    Flynn, E.K.2    Vilagos, B.3    Richson, U.4    Swaminathan, S.5    Bosnjak, B.6
  • 109
    • 84890098871 scopus 로고    scopus 로고
    • Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway
    • Redford PS, Mayer-Barber KD, McNab FW, Stavropoulos E, Wack A, Sher A, et al. Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway. J Infect Dis (2014) 209:270-4. doi:10.1093/infdis/jit424
    • (2014) J Infect Dis , vol.209 , pp. 270-274
    • Redford, P.S.1    Mayer-Barber, K.D.2    McNab, F.W.3    Stavropoulos, E.4    Wack, A.5    Sher, A.6
  • 110
    • 79951740151 scopus 로고    scopus 로고
    • Type I interferon inhibits interleukin-1 production and inflammasome activation
    • Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Förster I, et al. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity (2011) 34:213-23. doi:10.1016/j.immuni.2011.02.006
    • (2011) Immunity , vol.34 , pp. 213-223
    • Guarda, G.1    Braun, M.2    Staehli, F.3    Tardivel, A.4    Mattmann, C.5    Förster, I.6
  • 111
    • 17844384265 scopus 로고    scopus 로고
    • Role of type I IFNs in pulmonary complications of Pneumocystis murina infection
    • Meissner NN, Swain S, Tighe M, Harmsen A, Harmsen A. Role of type I IFNs in pulmonary complications of Pneumocystis murina infection. J Immunol (2005) 174:5462-71. doi:10.4049/jimmunol.174.9.5462
    • (2005) J Immunol , vol.174 , pp. 5462-5471
    • Meissner, N.N.1    Swain, S.2    Tighe, M.3    Harmsen, A.4    Harmsen, A.5
  • 112
    • 84946600698 scopus 로고    scopus 로고
    • Cryptococcus neoformans infection in mice lacking type I interferon signaling leads to increased fungal clearance and IL-4-dependent mucin production in the lungs
    • Sato K, Yamamoto H, Nomura T, Matsumoto I, Miyasaka T, Zong T, et al. Cryptococcus neoformans infection in mice lacking type I interferon signaling leads to increased fungal clearance and IL-4-dependent mucin production in the lungs. PLoS One (2015) 10:e0138291. doi:10.1371/journal.pone.0138291
    • (2015) PLoS One , vol.10
    • Sato, K.1    Yamamoto, H.2    Nomura, T.3    Matsumoto, I.4    Miyasaka, T.5    Zong, T.6
  • 113
    • 47949086661 scopus 로고    scopus 로고
    • IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis
    • Biondo C, Midiri A, Gambuzza M, Gerace E, Falduto M, Galbo R, et al. IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis. J Immunol (2008) 181:566-73. doi:10.4049/jimmunol.181.1.566
    • (2008) J Immunol , vol.181 , pp. 566-573
    • Biondo, C.1    Midiri, A.2    Gambuzza, M.3    Gerace, E.4    Falduto, M.5    Galbo, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.