Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 309, Issue 2, 2015, Pages L158-L167

  Lee, Benjamin ^a   Robinson, Keven M ^a,b   McHugh, Kevin J ^a   Scheller, Erich V ^a   Mandalapu, Sivanarayana ^a   Chen, Chen ^c   Di, Y Peter ^c   Clay, Michelle E ^a   Enelow, Richard I ^d   Dubin, Patricia J ^a   Alcorn, John F ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Coinfection; Escherichia coli; Influenza A; Staphylococcus aureus; Type I interferon

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN; PROTEIN BPIFA1; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR GAMMA; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; ANTIMICROBIAL CATIONIC PEPTIDE; IFNAR1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL PNEUMONIA; CONTROLLED STUDY; ESCHERICHIA COLI; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFECTION SENSITIVITY; INFLAMMATORY CELL; INFLUENZA A; INFLUENZA VIRUS A; LUNG HOMOGENATE; MALE; MIXED INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; ANIMAL; C57BL MOUSE; DISEASE PREDISPOSITION; ESCHERICHIA COLI INFECTION; IMMUNOLOGY; INFLUENZA A VIRUS; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PHYSIOLOGY; PNEUMONIA; STAPHYLOCOCCUS INFECTION; VIROLOGY;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; COINFECTION; DISEASE SUSCEPTIBILITY; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; INFLUENZA A VIRUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; PNEUMONIA; PNEUMONIA, BACTERIAL; RECEPTOR, INTERFERON ALPHA-BETA; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84937396412     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00338.2014     Document Type: Article

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