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Journal of Virology
Volumn 89, Issue 8, 2015, Pages 4405-4420
Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication
Author keywords

[No Author keywords available]
Indexed keywords

CYTOKINE; INTERFERON; PROGRAMMED DEATH 1 LIGAND 1; T CELL IMMUNOGLOBULIN MUCIN DOMAIN CONTAINING MOLECULE 3; UNCLASSIFIED DRUG; HAVCR2 PROTEIN, MOUSE; VIRUS RECEPTOR;
EID: 84925427995     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03275-14     Document Type: Article
Times cited : (29)
References (81)
  • 2
    • 84861547957 scopus 로고    scopus 로고
    • Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults
    • Widmer K, Zhu Y, Williams JV, Griffin MR, Edwards KM, Talbot HK. 2012. Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults. J Infect Dis 206: 56-62. http://dx.doi.org/10.1093/infdis/jis309.
    • (2012) J Infect Dis , vol.206 , pp. 56-62
    • Widmer, K.1    Zhu, Y.2    Williams, J.V.3    Griffin, M.R.4    Edwards, K.M.5    Talbot, H.K.6
  • 4
    • 24644471867 scopus 로고    scopus 로고
    • A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections
    • Williams JV, Martino R, Rabella N, Otegui M, Parody R, Heck JM, Crowe JE, Jr. 2005. A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis 192:1061-1065. http://dx.doi.org/10.1086/432732.
    • (2005) J Infect Dis , vol.192 , pp. 1061-1065
    • Williams, J.V.1    Martino, R.2    Rabella, N.3    Otegui, M.4    Parody, R.5    Heck, J.M.6    Crowe, J.E.7
  • 7
    • 79957977434 scopus 로고    scopus 로고
    • The human metapneumovirus: a case series and review of the literature
    • Shahda S, Carlos WG, Kiel PJ, Khan BA, Hage CA. 2011. The human metapneumovirus: a case series and review of the literature. Transpl Infect Dis 13:324-328. http://dx.doi.org/10.1111/j.1399-3062.2010.00575.x.
    • (2011) Transpl Infect Dis , vol.13 , pp. 324-328
    • Shahda, S.1    Carlos, W.G.2    Kiel, P.J.3    Khan, B.A.4    Hage, C.A.5
  • 8
    • 58149098611 scopus 로고    scopus 로고
    • Human metapneumovirus infections in adults: another piece of the puzzle
    • Walsh EE, Peterson DR, Falsey AR. 2008. Human metapneumovirus infections in adults: another piece of the puzzle. Arch Intern Med 168: 2489-2496. http://dx.doi.org/10.1001/archinte.168.22.2489.
    • (2008) Arch Intern Med , vol.168 , pp. 2489-2496
    • Walsh, E.E.1    Peterson, D.R.2    Falsey, A.R.3
  • 11
    • 84886738768 scopus 로고    scopus 로고
    • Seroepidemiologies of human metapneumovirus and respiratory syncytial virus in young children, determined with a new recombinant fusion protein enzyme-linked immunosorbent assay
    • Dunn SR, Ryder AB, Tollefson SJ, Xu M, Saville BR, Williams JV. 2013. Seroepidemiologies of human metapneumovirus and respiratory syncytial virus in young children, determined with a new recombinant fusion protein enzyme-linked immunosorbent assay. Clin Vaccine Immunol 20: 1654-1656. http://dx.doi.org/10.1128/CVI.00750-12.
    • (2013) Clin Vaccine Immunol , vol.20 , pp. 1654-1656
    • Dunn, S.R.1    Ryder, A.B.2    Tollefson, S.J.3    Xu, M.4    Saville, B.R.5    Williams, J.V.6
  • 13
    • 78049364147 scopus 로고    scopus 로고
    • Longitudinal course of human metapneumovirus antibody titers and reinfection in healthy adults
    • Okamoto M, Sugawara K, Takashita E, Muraki Y, Hongo S, Nishimura H, Matsuzaki Y. 2010. Longitudinal course of human metapneumovirus antibody titers and reinfection in healthy adults. J Med Virol 82:2092-2096. http://dx.doi.org/10.1002/jmv.21920.
    • (2010) J Med Virol , vol.82 , pp. 2092-2096
    • Okamoto, M.1    Sugawara, K.2    Takashita, E.3    Muraki, Y.4    Hongo, S.5    Nishimura, H.6    Matsuzaki, Y.7
  • 16
    • 84922569328 scopus 로고    scopus 로고
    • A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus
    • Schuster JE, Cox RG, Hastings AK, Boyd KL, Wadia J, Chen Z, Burton DR, Williamson RA, Williams JV. 2015. A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus. J Infect Dis 211:216-225. http://dx.doi.org/10.1093/infdis/jiu307.
    • (2015) J Infect Dis , vol.211 , pp. 216-225
    • Schuster, J.E.1    Cox, R.G.2    Hastings, A.K.3    Boyd, K.L.4    Wadia, J.5    Chen, Z.6    Burton, D.R.7    Williamson, R.A.8    Williams, J.V.9
  • 17
    • 58149401441 scopus 로고    scopus 로고
    • Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus
    • Ulbrandt ND, Ji H, Patel NK, Barnes AS, Wilson S, Kiener PA, Suzich J, McCarthy MP. 2008. Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus. J Gen Virol 89:3113-3118. http://dx.doi.org/10.1099/vir.0.2008/005199-0.
    • (2008) J Gen Virol , vol.89 , pp. 3113-3118
    • Ulbrandt, N.D.1    Ji, H.2    Patel, N.K.3    Barnes, A.S.4    Wilson, S.5    Kiener, P.A.6    Suzich, J.7    McCarthy, M.P.8
  • 18
    • 80052898726 scopus 로고    scopus 로고
    • Human metapneumovirus inhibits IFN-beta signaling by downregulating Jak1 and Tyk2 cellular levels
    • Ren J, Kolli D, Liu T, Xu R, Garofalo RP, Casola A, Bao X. 2011. Human metapneumovirus inhibits IFN-beta signaling by downregulating Jak1 and Tyk2 cellular levels. PLoS One 6:e24496. http://dx.doi.org/10.1371/journal.pone.0024496.
    • (2011) PLoS One , vol.6
    • Ren, J.1    Kolli, D.2    Liu, T.3    Xu, R.4    Garofalo, R.P.5    Casola, A.6    Bao, X.7
  • 19
    • 45249091224 scopus 로고    scopus 로고
    • Human metapneumovirus inhibits IFN-alpha signaling through inhibition of STAT1 phosphorylation
    • Dinwiddie DL, Harrod KS. 2008. Human metapneumovirus inhibits IFN-alpha signaling through inhibition of STAT1 phosphorylation. Am J Respir Cell Mol Biol 38:661-670. http://dx.doi.org/10.1165/rcmb.2007-0285OC.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , pp. 661-670
    • Dinwiddie, D.L.1    Harrod, K.S.2
  • 20
    • 0035094982 scopus 로고    scopus 로고
    • Host defense, viruses and apoptosis
    • Barber GN. 2001. Host defense, viruses and apoptosis. Cell Death Differ 8:113-126. http://dx.doi.org/10.1038/sj.cdd.4400823.
    • (2001) Cell Death Differ , vol.8 , pp. 113-126
    • Barber, G.N.1
  • 21
    • 46249115827 scopus 로고    scopus 로고
    • Interferon-inducible antiviral effectors
    • Sadler AJ, Williams BR. 2008. Interferon-inducible antiviral effectors. Nat Rev Immunol 8:559-568. http://dx.doi.org/10.1038/nri2314.
    • (2008) Nat Rev Immunol , vol.8 , pp. 559-568
    • Sadler, A.J.1    Williams, B.R.2
  • 22
    • 0034954034 scopus 로고    scopus 로고
    • Interferons alpha and beta as immune regulators-a new look
    • Biron CA. 2001. Interferons alpha and beta as immune regulators-a new look. Immunity 14:661-664. http://dx.doi.org/10.1016/S1074-7613(01)00154-6.
    • (2001) Immunity , vol.14 , pp. 661-664
    • Biron, C.A.1
  • 23
    • 33644837684 scopus 로고    scopus 로고
    • Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
    • Havenar-Daughton C, Kolumam GA, Murali-Krishna K. 2006. Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. JImmunol 176:3315-3319. http://dx.doi.org/10.4049/jimmunol.176.6.3315.
    • (2006) JImmunol , vol.176 , pp. 3315-3319
    • Havenar-Daughton, C.1    Kolumam, G.A.2    Murali-Krishna, K.3
  • 24
    • 39149125164 scopus 로고    scopus 로고
    • Type I interferon as a stimulus for crosspriming
    • Le Bon A, Tough DF. 2008. Type I interferon as a stimulus for crosspriming. Cytokine Growth Factor Rev 19:33-40. http://dx.doi.org/10.1016/j.cytogfr.2007.10.007.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 33-40
    • Le Bon, A.1    Tough, D.F.2
  • 25
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam GA, Thomas S, Thompson LJ, Sprent J, Murali-Krishna K. 2005. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J Exp Med 202:637-650. http://dx.doi.org/10.1084/jem.20050821.
    • (2005) J Exp Med , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 30
    • 33748098860 scopus 로고    scopus 로고
    • PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and-gamma and mediatesTcell apoptosis
    • Mühlbauer M, Fleck M, Schutz C, Weiss T, Froh M, Blank C, Scholmerich J, Hellerbrand C. 2006. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and-gamma and mediatesTcell apoptosis. J Hepatol 45:520-528. http://dx.doi.org/10.1016/j.jhep.2006.05.007.
    • (2006) J Hepatol , vol.45 , pp. 520-528
    • Mühlbauer, M.1    Fleck, M.2    Schutz, C.3    Weiss, T.4    Froh, M.5    Blank, C.6    Scholmerich, J.7    Hellerbrand, C.8
  • 31
    • 84887210320 scopus 로고    scopus 로고
    • Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection
    • McNally B, Ye F, Willette M, Flano E. 2013. Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection. J Virol 87:12916-12924. http://dx.doi.org/10.1128/JVI.02423-13.
    • (2013) J Virol , vol.87 , pp. 12916-12924
    • McNally, B.1    Ye, F.2    Willette, M.3    Flano, E.4
  • 32
    • 23844454493 scopus 로고    scopus 로고
    • The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity
    • Williams JV, Tollefson SJ, Johnson JE, Crowe JE, Jr. 2005. The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol 79:10944-10951. http://dx.doi.org/10.1128/JVI.79.17.10944-10951.2005.
    • (2005) J Virol , vol.79 , pp. 10944-10951
    • Williams, J.V.1    Tollefson, S.J.2    Johnson, J.E.3    Crowe, J.E.4
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408. http://dx.doi.org/10.1006/meth.2001.1262.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 0032964991 scopus 로고    scopus 로고
    • Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus
    • Hartert TV, Wheeler AP, Sheller JR. 1999. Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus. Chest 115:475-481. http://dx.doi.org/10.1378/chest.115.2.475.
    • (1999) Chest , vol.115 , pp. 475-481
    • Hartert, T.V.1    Wheeler, A.P.2    Sheller, J.R.3
  • 36
    • 0015920474 scopus 로고
    • Development of pulsus paradoxus in the presence of airways obstruction
    • Rebuck AS, Pengelly LD. 1973. Development of pulsus paradoxus in the presence of airways obstruction. N Engl J Med 288:66-69. http://dx.doi.org/10.1056/NEJM197301112880203.
    • (1973) N Engl J Med , vol.288 , pp. 66-69
    • Rebuck, A.S.1    Pengelly, L.D.2
  • 37
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
    • Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, Oh S, Shin JG, Yao S, Chen L, Choi IH. 2006. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS Lett 580:755-762. http://dx.doi.org/10.1016/j.febslet.2005.12.093.
    • (2006) FEBS Lett , vol.580 , pp. 755-762
    • Lee, S.J.1    Jang, B.C.2    Lee, S.W.3    Yang, Y.I.4    Suh, S.I.5    Park, Y.M.6    Oh, S.7    Shin, J.G.8    Yao, S.9    Chen, L.10    Choi, I.H.11
  • 39
    • 84899746524 scopus 로고    scopus 로고
    • Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection
    • Srivastava S, Koch MA, Pepper M, Campbell DJ. 2014. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med 211:961-974. http://dx.doi.org/10.1084/jem.20131556.
    • (2014) J Exp Med , vol.211 , pp. 961-974
    • Srivastava, S.1    Koch, M.A.2    Pepper, M.3    Campbell, D.J.4
  • 40
    • 77955169480 scopus 로고    scopus 로고
    • Interferon-alpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses
    • Golding A, Rosen A, Petri M, Akhter E, Andrade F. 2010. Interferon-alpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses. Immunology 131:107-117. http://dx.doi.org/10.1111/j.1365-2567.2010.03280.x.
    • (2010) Immunology , vol.131 , pp. 107-117
    • Golding, A.1    Rosen, A.2    Petri, M.3    Akhter, E.4    Andrade, F.5
  • 42
    • 73149090090 scopus 로고    scopus 로고
    • Effect of IFN-beta therapy on the frequency and function of CD4(+)CD25(+) regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study
    • Namdar A, Nikbin B, Ghabaee M, Bayati A, Izad M. 2010. Effect of IFN-beta therapy on the frequency and function of CD4(+)CD25(+) regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study. J Neuroimmunol 218:120-124. http://dx.doi.org/10.1016/j.jneuroim.2009.10.013.
    • (2010) J Neuroimmunol , vol.218 , pp. 120-124
    • Namdar, A.1    Nikbin, B.2    Ghabaee, M.3    Bayati, A.4    Izad, M.5
  • 43
    • 77956913784 scopus 로고    scopus 로고
    • + CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection
    • + CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J Immunol 185: 2382-2392. http://dx.doi.org/10.4049/jimmunol.1000423.
    • (2010) J Immunol , vol.185 , pp. 2382-2392
    • Fulton, R.B.1    Meyerholz, D.K.2    Varga, S.M.3
  • 45
    • 30944435241 scopus 로고    scopus 로고
    • CD11b regulates recruitment of alveolar macrophages but not pulmonary dendritic cells after pneumococcal challenge
    • Kirby AC, Raynes JG, Kaye PM. 2006. CD11b regulates recruitment of alveolar macrophages but not pulmonary dendritic cells after pneumococcal challenge. J Infect Dis 193:205-213. http://dx.doi.org/10.1086/498874.
    • (2006) J Infect Dis , vol.193 , pp. 205-213
    • Kirby, A.C.1    Raynes, J.G.2    Kaye, P.M.3
  • 47
    • 79952237074 scopus 로고    scopus 로고
    • Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice
    • Seo SU, Kwon HJ, Ko HJ, Byun YH, Seong BL, Uematsu S, Akira S, Kweon MN. 2011. Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice. PLoS Pathog 7:e1001304. http://dx.doi.org/10.1371/journal.ppat.1001304.
    • (2011) PLoS Pathog , vol.7
    • Seo, S.U.1    Kwon, H.J.2    Ko, H.J.3    Byun, Y.H.4    Seong, B.L.5    Uematsu, S.6    Akira, S.7    Kweon, M.N.8
  • 49
    • 34250362702 scopus 로고    scopus 로고
    • Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus
    • Johansson C, Wetzel JD, He J, Mikacenic C, Dermody TS, Kelsall BL. 2007. Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus. J Exp Med 204:1349-1358. http://dx.doi.org/10.1084/jem.20061587.
    • (2007) J Exp Med , vol.204 , pp. 1349-1358
    • Johansson, C.1    Wetzel, J.D.2    He, J.3    Mikacenic, C.4    Dermody, T.S.5    Kelsall, B.L.6
  • 50
    • 18944405626 scopus 로고    scopus 로고
    • Role for innate IFNs in determining respiratory syncytial virus immunopathology
    • Johnson TR, Mertz SE, Gitiban N, Hammond S, Legallo R, Durbin RK, Durbin JE. 2005. Role for innate IFNs in determining respiratory syncytial virus immunopathology. J Immunol 174:7234-7241. http://dx.doi.org/10.4049/jimmunol.174.11.7234.
    • (2005) J Immunol , vol.174 , pp. 7234-7241
    • Johnson, T.R.1    Mertz, S.E.2    Gitiban, N.3    Hammond, S.4    Legallo, R.5    Durbin, R.K.6    Durbin, J.E.7
  • 52
    • 18644364701 scopus 로고    scopus 로고
    • A type I interferon autocrineparacrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
    • Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates EE, Trinchieri G, Caux C, Garrone P. 2005. A type I interferon autocrineparacrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med 201:1435-1446. http://dx.doi.org/10.1084/jem.20041964.
    • (2005) J Exp Med , vol.201 , pp. 1435-1446
    • Gautier, G.1    Humbert, M.2    Deauvieau, F.3    Scuiller, M.4    Hiscott, J.5    Bates, E.E.6    Trinchieri, G.7    Caux, C.8    Garrone, P.9
  • 53
    • 37549005122 scopus 로고    scopus 로고
    • Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production
    • Rudd BD, Luker GD, Luker KE, Peebles RS, Lukacs NW. 2007. Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production. Viral Immunol 20:531-540. http://dx.doi.org/10.1089/vim.2007.0057.
    • (2007) Viral Immunol , vol.20 , pp. 531-540
    • Rudd, B.D.1    Luker, G.D.2    Luker, K.E.3    Peebles, R.S.4    Lukacs, N.W.5
  • 54
    • 84899829425 scopus 로고    scopus 로고
    • Interferon-alpha/beta receptor signaling amplifies early proinflammatory cytokine production in the lung during respiratory syncytial virus infection
    • Goritzka M, Durant LR, Pereira C, Salek-Ardakani S, Openshaw PJ, Johansson C. 2014. Interferon-alpha/beta receptor signaling amplifies early proinflammatory cytokine production in the lung during respiratory syncytial virus infection. J Virol 88:6128-6136. http://dx.doi.org/10.1128/JVI.00333-14.
    • (2014) J Virol , vol.88 , pp. 6128-6136
    • Goritzka, M.1    Durant, L.R.2    Pereira, C.3    Salek-Ardakani, S.4    Openshaw, P.J.5    Johansson, C.6
  • 57
    • 0036926154 scopus 로고    scopus 로고
    • Natural type I interferon-producing cells as a link between innate and adaptive immunity
    • Kadowaki N, Liu YJ. 2002. Natural type I interferon-producing cells as a link between innate and adaptive immunity. Hum Immunol 63:1126-1132. http://dx.doi.org/10.1016/S0198-8859(02)00751-6.
    • (2002) Hum Immunol , vol.63 , pp. 1126-1132
    • Kadowaki, N.1    Liu, Y.J.2
  • 58
    • 33846597964 scopus 로고    scopus 로고
    • Opposing effects of Toll-like receptor stimulation induce autoimmunity or tolerance
    • Ehlers M, Ravetch JV. 2007. Opposing effects of Toll-like receptor stimulation induce autoimmunity or tolerance. Trends Immunol 28:74-79. http://dx.doi.org/10.1016/j.it.2006.12.006.
    • (2007) Trends Immunol , vol.28 , pp. 74-79
    • Ehlers, M.1    Ravetch, J.V.2
  • 59
    • 84876271525 scopus 로고    scopus 로고
    • Crosspriming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8alpha(+) dendritic cells
    • Azuma M, Ebihara T, Oshiumi H, Matsumoto M, Seya T. 2012. Crosspriming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8alpha(+) dendritic cells. Oncoimmunology 1:581-592. http://dx.doi.org/10.4161/onci.19893.
    • (2012) Oncoimmunology , vol.1 , pp. 581-592
    • Azuma, M.1    Ebihara, T.2    Oshiumi, H.3    Matsumoto, M.4    Seya, T.5
  • 60
    • 11844269957 scopus 로고    scopus 로고
    • Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223)
    • Workman CJ, Vignali DA. 2005. Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). J Immunol 174:688-695. http://dx.doi.org/10.4049/jimmunol.174.2.688.
    • (2005) J Immunol , vol.174 , pp. 688-695
    • Workman, C.J.1    Vignali, D.A.2
  • 62
  • 63
    • 84884561907 scopus 로고    scopus 로고
    • Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy
    • Nirschl CJ, Drake CG. 2013. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res 19:4917-4924. http://dx.doi.org/10.1158/1078-0432.CCR-12-1972.
    • (2013) Clin Cancer Res , vol.19 , pp. 4917-4924
    • Nirschl, C.J.1    Drake, C.G.2
  • 64
    • 84859403357 scopus 로고    scopus 로고
    • Inhibitory receptors on lymphocytes: insights from infections
    • Odorizzi PM, Wherry EJ. 2012. Inhibitory receptors on lymphocytes: insights from infections. J Immunol 188:2957-2965. http://dx.doi.org/10.4049/jimmunol.1100038.
    • (2012) J Immunol , vol.188 , pp. 2957-2965
    • Odorizzi, P.M.1    Wherry, E.J.2
  • 65
    • 0038143288 scopus 로고    scopus 로고
    • The TIM gene family: emerging roles in immunity and disease
    • Kuchroo VK, Umetsu DT, DeKruyff RH, Freeman GJ. 2003. The TIM gene family: emerging roles in immunity and disease. Nat Rev Immunol 3:454-462. http://dx.doi.org/10.1038/nri1111.
    • (2003) Nat Rev Immunol , vol.3 , pp. 454-462
    • Kuchroo, V.K.1    Umetsu, D.T.2    DeKruyff, R.H.3    Freeman, G.J.4
  • 67
    • 33947113954 scopus 로고    scopus 로고
    • Structures of T cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family
    • Santiago C, Ballesteros A, Tami C, Martinez-Munoz L, Kaplan GG, Casasnovas JM. 2007. Structures of T cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family. Immunity 26:299-310. http://dx.doi.org/10.1016/j.immuni.2007.01.014.
    • (2007) Immunity , vol.26 , pp. 299-310
    • Santiago, C.1    Ballesteros, A.2    Tami, C.3    Martinez-Munoz, L.4    Kaplan, G.G.5    Casasnovas, J.M.6
  • 70
    • 78649903057 scopus 로고    scopus 로고
    • Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
    • McMahan RH, Golden-Mason L, Nishimura MI, McMahon BJ, Kemper M, Allen TM, Gretch DR, Rosen HR. 2010. Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J Clin Invest 120:4546-4557. http://dx.doi.org/10.1172/JCI43127.
    • (2010) J Clin Invest , vol.120 , pp. 4546-4557
    • McMahan, R.H.1    Golden-Mason, L.2    Nishimura, M.I.3    McMahon, B.J.4    Kemper, M.5    Allen, T.M.6    Gretch, D.R.7    Rosen, H.R.8
  • 72
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, Anderson AC. 2010. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207:2187-2194. http://dx.doi.org/10.1084/jem.20100643.
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5    Anderson, A.C.6
  • 73
    • 79956103042 scopus 로고    scopus 로고
    • Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors
    • Ngiow SF, von Scheidt B, Akiba H, Yagita H, Teng MW, Smyth MJ. 2011. Anti-TIM3 antibody promotes T cell IFN-gamma-mediated antitumor immunity and suppresses established tumors. Cancer Res 71:3540-3551. http://dx.doi.org/10.1158/0008-5472.CAN-11-0096.
    • (2011) Cancer Res , vol.71 , pp. 3540-3551
    • Ngiow, S.F.1    von Scheidt, B.2    Akiba, H.3    Yagita, H.4    Teng, M.W.5    Smyth, M.J.6
  • 74
    • 77954053238 scopus 로고    scopus 로고
    • Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response
    • Sehrawat S, Reddy PB, Rajasagi N, Suryawanshi A, Hirashima M, Rouse BT. 2010. Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response. PLoS Pathog 6:e1000882. http://dx.doi.org/10.1371/journal.ppat.1000882.
    • (2010) PLoS Pathog , vol.6
    • Sehrawat, S.1    Reddy, P.B.2    Rajasagi, N.3    Suryawanshi, A.4    Hirashima, M.5    Rouse, B.T.6
  • 75
    • 58449134844 scopus 로고    scopus 로고
    • + T cell responses
    • + T cell responses. PLoS One 4:e4204. http://dx.doi.org/10.1371/journal.pone.0004204.
    • (2009) PLoS One , vol.4
    • Kim, T.S.1    Braciale, T.J.2
  • 77
    • 18144379145 scopus 로고    scopus 로고
    • The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice
    • Alvarez R, Tripp RA. 2005. The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice. J Virol 79:5971-5978. http://dx.doi.org/10.1128/JVI.79.10.5971-5978.2005.
    • (2005) J Virol , vol.79 , pp. 5971-5978
    • Alvarez, R.1    Tripp, R.A.2
  • 78
    • 35148884680 scopus 로고    scopus 로고
    • Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus
    • Melendi GA, Zavala F, Buchholz UJ, Boivin G, Collins PL, Kleeberger SR, Polack FP. 2007. Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus. J Virol 81:11461-11467. http://dx.doi.org/10.1128/JVI.02423-06.
    • (2007) J Virol , vol.81 , pp. 11461-11467
    • Melendi, G.A.1    Zavala, F.2    Buchholz, U.J.3    Boivin, G.4    Collins, P.L.5    Kleeberger, S.R.6    Polack, F.P.7
  • 79
    • 0033861859 scopus 로고    scopus 로고
    • T-cell subsets (Th1 versus Th2)
    • quiz 18:21
    • Romagnani S. 2000. T-cell subsets (Th1 versus Th2). Ann Allergy Asthma Immunol 85:9-18; quiz 18:21. http://dx.doi.org/10.1016/S1081-1206(10)62426-X.
    • (2000) Ann Allergy Asthma Immunol , vol.85 , pp. 9-18
    • Romagnani, S.1
  • 80
    • 0023492716 scopus 로고
    • Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T-cell subsets
    • Locksley RM, Heinzel FP, Sadick MD, Holaday BJ, Gardner KD, Jr. 1987. Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T-cell subsets. Ann Inst Pasteur Immunol 138:744-749. http://dx.doi.org/10.1016/S0769-2625(87)80030-2.
    • (1987) Ann Inst Pasteur Immunol , vol.138 , pp. 744-749
    • Locksley, R.M.1    Heinzel, F.P.2    Sadick, M.D.3    Holaday, B.J.4    Gardner, K.D.5
  • 81
    • 0027717408 scopus 로고
    • Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice
    • Gessner A, Blum H, Rollinghoff M. 1993. Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice. Immunobiology 189:419-435. http://dx.doi.org/10.1016/S0171-2985(11)80414-6.
    • (1993) Immunobiology , vol.189 , pp. 419-435
    • Gessner, A.1    Blum, H.2    Rollinghoff, M.3

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