Cryptococcus neoformans infection in mice lacking type i interferon signaling leads to increased fungal clearance and IL-4-dependent mucin production in the lungs

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Sato, Ko ^a   Yamamoto, Hideki ^a   Nomura, Toshiki ^a   Matsumoto, Ikumi ^a   Miyasaka, Tomomitsu ^a,c   Zong, Tong ^a   Kanno, Emi ^a   Uno, Kazuko ^b   Ishii, Keiko ^a   Kawakami, Kazuyoshi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Louis Pasteur Center for Medical Research   (Japan)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; INTERFERON; INTERLEUKIN 4; INTERLEUKIN 4 ANTIBODY; MUCIN; RECOMBINANT ALPHA INTERFERON; IFNAR1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; DENDRITIC CELL; EPITHELIUM CELL; FUNGAL STRAIN; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; MOUSE; NONHUMAN; PATHOGEN CLEARANCE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; PULMONARY CRYPTOCOCCOSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CRYPTOCOCCOSIS; GENETICS; KNOCKOUT MOUSE; LUNG; METABOLISM; PHYSIOLOGY;

ANIMALS; CRYPTOCOCCOSIS; INTERFERON TYPE I; INTERLEUKIN-4; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCINS; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION;

EID: 84946600698     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138291     Document Type: Article

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