How RIG-I like receptors activate MAVS

Current Opinion in Virology

Volumn 12, Issue , 2015, Pages 91-98

  Wu, Bin ^a,b   Hur, Sun ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; PEPTIDES AND PROTEINS; RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; RETINOIC ACID INDUCIBLE PROTEIN I LIKE RECEPTOR; TETRAMER; UBIQUITIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; INTERFERON; PATTERN RECOGNITION RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VIRUS RNA; VISA PROTEIN, HUMAN;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; DEAD BOX PROTEIN 58; DEAD-BOX RNA HELICASES; HUMANS; INTERFERON TYPE I; RECEPTORS, PATTERN RECOGNITION; RNA, VIRAL; SIGNAL TRANSDUCTION;

EID: 84930934680     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2015.04.004     Document Type: Review

References (43)

1. H. Kato, K. Takahasi, and T. Fujita RIG-I-like receptors: cytoplasmic sensors for non-self RNA Immunol Rev 243 2011 91 98
2. H. Kato Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses Nature 441 2006 101 105
3. M.Y. Loo Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity J Virol 82 2008 335 345
4. L. Gitlin Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus Proc Natl Acad Sci USA 103 2006 8459 8464
5. L.G. Xu VISA is an adapter protein required for virus-triggered IFN-beta signaling Mol Cell 19 2005 727 740
6. R.B. Seth Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3 Cell 122 2005 669 682
7. E. Meylan Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus Nature 437 2005 1167 1172
8. T. Kawai IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction Nat Immunol 6 2005 981 988
9. E. Kowalinski Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA Cell 147 2011 423 435
10. E. Dixit Peroxisomes are signaling platforms for antiviral innate immunity Cell 141 2010 668 681
11. S.K. Saha Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif EMBO J 25 2006 3257 3263
12. S. Paz A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response Cell Res 21 2011 895 910
13. S. Liu MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades eLife 2 2013 pe00785
14. R. Ferrao, and H. Wu Helical assembly in the death domain (DD) superfamily Curr Opin Struct Biol 22 2012 241 247
15. E.D. Tang, and C.Y. Wang MAVS self-association mediates antiviral innate immune signaling J Virol 83 2009 3420 3428
16. F. Hou MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response Cell 146 2011 448 461
17. A. Peisley RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner Mol Cell 51 2013 573 583
18. A. Peisley Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I Nature 509 2014 110 114
19. H. Xu Structural basis for the prion-like MAVS filaments in antiviral innate immunity Elife 3 2014 pe01489
20. C. Castanier Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway EMBO Rep 11 2010 133 138
21. K. Onoguchi Virus-Infection or 5′ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1 PLoS Pathog 6 2010 pe1001012
22. W. Zeng Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity Cell 141 2010 315 330
23. X. Jiang Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response Immunity 36 2012 959 973
24. W. Zeng Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3 Mol Cell 36 2009 315 325
25. B. Wu Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5 Cell 152 2013 276 289
26. B. Wu Molecular imprinting as a signal-activation mechanism of the viral RNA sensor RIG-I Mol Cell 55 2014 511 523
27. E.M. Harhaj, and V.M. Dixit Regulation of NF-κB by deubiquitinases Immunol Rev 246 2012 107 124
28. Z.J. Chen Ubiquitination in signaling to and activation of IKK Immunol Rev 246 2012 95 106
29. M.U. Gack TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity Nature 446 2007 916 920
30. J.R. Patel ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon EMBO Rep 14 2013 780 787
31. M. Schlee Recognition of 5′triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus Immunity 31 2009 25 34
32. A. Kohlway Defining the functional determinants for RNA surveillance by RIG-I EMBO Rep 14 2013 772 779
33. M. Binder Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I) J Biol Chem 286 2011 27278 27287
34. E.H. Egelman Ambiguities in helical reconstruction eLIFE 3 2014 pe04969
35. E.H. Egelman Reconstruction of helical filaments and tubes Methods Enzymol 482 2010 167 183
36. A. Peisley Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition Proc Natl Acad Sci USA 108 2011 21010 21015
37. I.C. Berke, and Y. Modis MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA EMBO J 7 2012 1714 1726
38. H. Wu Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily Adv Protein Chem 68 2004 225 279
39. S. Takamatsu Functional characterization of domains of IPS-1 using an inducible oligomerization system PLoS One 8 2013 e53578
40. J.M. Kollman Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry Nature 466 2010 879 882
41. S.-C. Lin, Y.-C. Lo, and H. Wu Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling Nature 465 2010 885 890
42. A. Lu Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes Cell 156 2014 1194 1206
43. X. Cai Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation Cell 156 2014 1207 1222