Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Cell Host and Microbe

Volumn 19, Issue 2, 2016, Pages 181-193

  Channappanavar, Rudragouda ^a   Fehr, Anthony R ^a   Vijay, Rahul ^a   Mack, Matthias ^b   Zhao, Jincun ^a,c   Meyerholz, David K ^d   Perlman, Stanley ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; CHEMOKINE; CYTOKINE; INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; IMMUNOPATHOLOGY; INFLAMMATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARS CORONAVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS LOAD; VIRUS PNEUMONIA; VIRUS REPLICATION; VIRUS TITRATION; ANIMAL; BAGG ALBINO MOUSE; COMPLICATION; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; MORTALITY; PHYSIOLOGY; PNEUMONIA; SEVERE ACUTE RESPIRATORY SYNDROME; VIROLOGY;

ANIMALS; FEMALE; HUMANS; INTERFERON TYPE I; MACROPHAGES; MICE; MICE, INBRED BALB C; MONOCYTES; PNEUMONIA; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME;

EID: 85012027074     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.01.007     Document Type: Article

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