-
1
-
-
84866244791
-
Autophagy in protein and organelle turnover
-
Mizushima N. Autophagy in protein and organelle turnover. Cold Spring Harb Symp Quant Biol 2011; 76: 397–402.
-
(2011)
Cold Spring Harb Symp Quant Biol
, vol.76
, pp. 397-402
-
-
Mizushima, N.1
-
2
-
-
84873660610
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med 2013; 368: 651–62.
-
(2013)
N Engl J Med
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
3
-
-
78651423598
-
Microautophagy of cytosolic proteins by late endosomes
-
Sahu R, Kaushik S, Clement CC et al. Microautophagy of cytosolic proteins by late endosomes. Dev Cell 2011; 20: 131–9.
-
(2011)
Dev Cell
, vol.20
, pp. 131-139
-
-
Sahu, R.1
Kaushik, S.2
Clement, C.C.3
-
4
-
-
84891741302
-
Chaperone-mediated autophagy: roles in disease and aging
-
Cuervo AM, Wong E. Chaperone-mediated autophagy: roles in disease and aging. Cell Res 2014; 24: 92–104.
-
(2014)
Cell Res
, vol.24
, pp. 92-104
-
-
Cuervo, A.M.1
Wong, E.2
-
6
-
-
84920463081
-
Immunologic manifestations of autophagy
-
Deretic V, Kimura T, Timmins G, Moseley P, Chauhan S, Mandell M. Immunologic manifestations of autophagy. J Clin Invest 2015; 125: 75–84.
-
(2015)
J Clin Invest
, vol.125
, pp. 75-84
-
-
Deretic, V.1
Kimura, T.2
Timmins, G.3
Moseley, P.4
Chauhan, S.5
Mandell, M.6
-
7
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013; 13: 722–37.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
8
-
-
84866767594
-
Autophagy in the regulation of pathogen replication and adaptive immunity
-
Randow F, Munz C. Autophagy in the regulation of pathogen replication and adaptive immunity. Trends Immunol 2012; 33: 475–87.
-
(2012)
Trends Immunol
, vol.33
, pp. 475-487
-
-
Randow, F.1
Munz, C.2
-
9
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007; 315: 1398–401.
-
(2007)
Science
, vol.315
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
10
-
-
84938693671
-
Secretory autophagy
-
Ponpuak M, Mandell MA, Kimura T, Chauhan S, Cleyrat C, Deretic V. Secretory autophagy. Curr Opin Cell Biol 2015; 35: 106–16.
-
(2015)
Curr Opin Cell Biol
, vol.35
, pp. 106-116
-
-
Ponpuak, M.1
Mandell, M.A.2
Kimura, T.3
Chauhan, S.4
Cleyrat, C.5
Deretic, V.6
-
11
-
-
84997830946
-
TRIM11 suppresses AIM2 inflammasome by degrading AIM2 via p62-dependent selective autophagy
-
Liu T, Tang Q, Liu K et al. TRIM11 suppresses AIM2 inflammasome by degrading AIM2 via p62-dependent selective autophagy. Cell Rep 2016; 16: 1988–2002.
-
(2016)
Cell Rep
, vol.16
, pp. 1988-2002
-
-
Liu, T.1
Tang, Q.2
Liu, K.3
-
12
-
-
84960432718
-
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
-
Kimura T, Jain A, Choi SW et al. TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. J Cell Biol 2015; 210: 973–89.
-
(2015)
J Cell Biol
, vol.210
, pp. 973-989
-
-
Kimura, T.1
Jain, A.2
Choi, S.W.3
-
13
-
-
84893912159
-
Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses
-
Liang Q, Seo GJ, Choi YJ et al. Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses. Cell Host Microbe 2014; 15: 228–38.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 228-238
-
-
Liang, Q.1
Seo, G.J.2
Choi, Y.J.3
-
14
-
-
84886789626
-
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling
-
Konno H, Konno K, Barber GN. Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling. Cell 2013; 155: 688–98.
-
(2013)
Cell
, vol.155
, pp. 688-698
-
-
Konno, H.1
Konno, K.2
Barber, G.N.3
-
15
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007; 39: 207–11.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
16
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596–604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
17
-
-
77953543312
-
T cell intrinsic roles of autophagy in promoting adaptive immunity
-
Walsh CM, Bell BD. T cell intrinsic roles of autophagy in promoting adaptive immunity. Curr Opin Immunol 2010; 22: 321–5.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 321-325
-
-
Walsh, C.M.1
Bell, B.D.2
-
18
-
-
84992740234
-
Autophagy beyond intracellular MHC class II antigen presentation
-
Munz C. Autophagy beyond intracellular MHC class II antigen presentation. Trends Immunol 2016; 37: 755–63.
-
(2016)
Trends Immunol
, vol.37
, pp. 755-763
-
-
Munz, C.1
-
19
-
-
84877610008
-
Bacterial subversion of host innate immune pathways
-
Baxt LA, Garza-Mayers AC, Goldberg MB. Bacterial subversion of host innate immune pathways. Science 2013; 340: 697–701.
-
(2013)
Science
, vol.340
, pp. 697-701
-
-
Baxt, L.A.1
Garza-Mayers, A.C.2
Goldberg, M.B.3
-
20
-
-
75649122282
-
Subversion of the cellular autophagy pathway by viruses
-
Kirkegaard K. Subversion of the cellular autophagy pathway by viruses. Curr Top Microbiol Immunol 2009; 335: 323–33.
-
(2009)
Curr Top Microbiol Immunol
, vol.335
, pp. 323-333
-
-
Kirkegaard, K.1
-
21
-
-
84961944001
-
Digesting the expanding mechanisms of autophagy
-
Ktistakis NT, Tooze SA. Digesting the expanding mechanisms of autophagy. Trends Cell Biol 2016; 26: 624–35.
-
(2016)
Trends Cell Biol
, vol.26
, pp. 624-635
-
-
Ktistakis, N.T.1
Tooze, S.A.2
-
22
-
-
84940467196
-
Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
-
Levine B, Liu R, Dong X, Zhong Q. Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology. Trends Cell Biol 2015; 25: 533–44.
-
(2015)
Trends Cell Biol
, vol.25
, pp. 533-544
-
-
Levine, B.1
Liu, R.2
Dong, X.3
Zhong, Q.4
-
23
-
-
84957440559
-
TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic
-
Lamb CA, Nuhlen S, Judith D et al. TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic. EMBO J 2016; 35: 281–301.
-
(2016)
EMBO J
, vol.35
, pp. 281-301
-
-
Lamb, C.A.1
Nuhlen, S.2
Judith, D.3
-
24
-
-
48249092267
-
Bcl-2 family members: dual regulators of apoptosis and autophagy
-
Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008; 4: 600–6.
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
25
-
-
34447099450
-
Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion
-
Nakatogawa H, Ichimura Y, Ohsumi Y. Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell 2007; 130: 165–78.
-
(2007)
Cell
, vol.130
, pp. 165-178
-
-
Nakatogawa, H.1
Ichimura, Y.2
Ohsumi, Y.3
-
28
-
-
84955242756
-
Ubiquitin-dependent and independent signals in selective autophagy
-
Khaminets A, Behl C, Dikic I. Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol 2016; 26: 6–16.
-
(2016)
Trends Cell Biol
, vol.26
, pp. 6-16
-
-
Khaminets, A.1
Behl, C.2
Dikic, I.3
-
29
-
-
84892875805
-
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
-
Shen HM, Mizushima N. At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy. Trends Biochem Sci 2014; 39: 61–71.
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 61-71
-
-
Shen, H.M.1
Mizushima, N.2
-
30
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13: 132–41.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
31
-
-
84876488191
-
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
-
Nazio F, Strappazzon F, Antonioli M et al. mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat Cell Biol 2013; 15: 406–16.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 406-416
-
-
Nazio, F.1
Strappazzon, F.2
Antonioli, M.3
-
32
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30: 678–88.
-
(2008)
Mol Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
33
-
-
61849102389
-
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
-
Zalckvar E, Berissi H, Mizrachy L et al. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep 2009; 10: 285–92.
-
(2009)
EMBO Rep
, vol.10
, pp. 285-292
-
-
Zalckvar, E.1
Berissi, H.2
Mizrachy, L.3
-
34
-
-
84905669136
-
Pattern recognition receptors and autophagy
-
Oh JE, Lee HK. Pattern recognition receptors and autophagy. Front Immunol 2014; 5: 300.
-
(2014)
Front Immunol
, vol.5
, pp. 300
-
-
Oh, J.E.1
Lee, H.K.2
-
35
-
-
83555168258
-
Inhibition of autophagy by TAB 2 and TAB 3
-
Criollo A, Niso-Santano M, Malik SA et al. Inhibition of autophagy by TAB 2 and TAB 3. EMBO J 2011; 30: 4908–20.
-
(2011)
EMBO J
, vol.30
, pp. 4908-4920
-
-
Criollo, A.1
Niso-Santano, M.2
Malik, S.A.3
-
36
-
-
77953858790
-
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
-
Shi CS, Kehrl JH. TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci Signal 2010; 3: ra42.
-
(2010)
Sci Signal
, vol.3
, pp. 42
-
-
Shi, C.S.1
Kehrl, J.H.2
-
38
-
-
84904438190
-
HIV infection: epidemiology, pathogenesis, treatment, and prevention
-
Maartens G, Celum C, Lewin SR. HIV infection: epidemiology, pathogenesis, treatment, and prevention. Lancet 2014; 384: 258–71.
-
(2014)
Lancet
, vol.384
, pp. 258-271
-
-
Maartens, G.1
Celum, C.2
Lewin, S.R.3
-
40
-
-
84937252674
-
HIV-1 assembly, release and maturation
-
Freed EO. HIV-1 assembly, release and maturation. Nat Rev Microbiol 2015; 13: 484–96.
-
(2015)
Nat Rev Microbiol
, vol.13
, pp. 484-496
-
-
Freed, E.O.1
-
43
-
-
84870324937
-
Retroviral integrase proteins and HIV-1 DNA integration
-
Krishnan L, Engelman A. Retroviral integrase proteins and HIV-1 DNA integration. J Biol Chem 2012; 287: 40858–66.
-
(2012)
J Biol Chem
, vol.287
, pp. 40858-40866
-
-
Krishnan, L.1
Engelman, A.2
-
44
-
-
84897965284
-
HIV-1 uncoating: connection to nuclear entry and regulation by host proteins
-
Ambrose Z, Aiken C. HIV-1 uncoating: connection to nuclear entry and regulation by host proteins. Virology 2014; 454–455: 371–9.
-
(2014)
Virology
, vol.454-455
, pp. 371-379
-
-
Ambrose, Z.1
Aiken, C.2
-
45
-
-
84929907228
-
Intrinsic host restrictions to HIV-1 and mechanisms of viral escape
-
Simon V, Bloch N, Landau NR. Intrinsic host restrictions to HIV-1 and mechanisms of viral escape. Nat Immunol 2015; 16: 546–53.
-
(2015)
Nat Immunol
, vol.16
, pp. 546-553
-
-
Simon, V.1
Bloch, N.2
Landau, N.R.3
-
46
-
-
84960129732
-
Remodeling of the host cell plasma membrane by HIV-1 Nef and Vpu: a strategy to ensure viral fitness and persistence
-
Sugden SM, Bego MG, Pham TN, Cohen EA. Remodeling of the host cell plasma membrane by HIV-1 Nef and Vpu: a strategy to ensure viral fitness and persistence. Viruses 2016; 8: 67.
-
(2016)
Viruses
, vol.8
, pp. 67
-
-
Sugden, S.M.1
Bego, M.G.2
Pham, T.N.3
Cohen, E.A.4
-
47
-
-
39349097864
-
Identification of host proteins required for HIV infection through a functional genomic screen
-
Brass AL, Dykxhoorn DM, Benita Y et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008; 319: 921–6.
-
(2008)
Science
, vol.319
, pp. 921-926
-
-
Brass, A.L.1
Dykxhoorn, D.M.2
Benita, Y.3
-
48
-
-
84858211760
-
Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors
-
Eekels JJ, Sagnier S, Geerts D, Jeeninga RE, Biard-Piechaczyk M, Berkhout B. Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors. Virol J 2012; 9: 9–69.
-
(2012)
Virol J
, vol.9
, pp. 9-69
-
-
Eekels, J.J.1
Sagnier, S.2
Geerts, D.3
Jeeninga, R.E.4
Biard-Piechaczyk, M.5
Berkhout, B.6
-
49
-
-
67649585835
-
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
-
Kyei GB, Dinkins C, Davis AS et al. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 2009; 186: 255–68.
-
(2009)
J Cell Biol
, vol.186
, pp. 255-268
-
-
Kyei, G.B.1
Dinkins, C.2
Davis, A.S.3
-
50
-
-
84855293818
-
IRGM is a common target of RNA viruses that subvert the autophagy network
-
Gregoire IP, Richetta C, Meyniel-Schicklin L et al. IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog 2011; 7: e1002422.
-
(2011)
PLoS Pathog
, vol.7
-
-
Gregoire, I.P.1
Richetta, C.2
Meyniel-Schicklin, L.3
-
51
-
-
84928926952
-
IRGM governs the core autophagy machinery to conduct antimicrobial defense
-
Chauhan S, Mandell MA, Deretic V. IRGM governs the core autophagy machinery to conduct antimicrobial defense. Mol Cell 2015; 58: 507–21.
-
(2015)
Mol Cell
, vol.58
, pp. 507-521
-
-
Chauhan, S.1
Mandell, M.A.2
Deretic, V.3
-
52
-
-
84870840400
-
Toll-like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1
-
Campbell GR, Spector SA. Toll-like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1. PLoS Pathog 2012; 8: e1003017.
-
(2012)
PLoS Pathog
, vol.8
-
-
Campbell, G.R.1
Spector, S.A.2
-
53
-
-
84876327825
-
Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy
-
Torresilla C, Larocque E, Landry S et al. Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy. J Virol 2013; 87: 5089–105.
-
(2013)
J Virol
, vol.87
, pp. 5089-5105
-
-
Torresilla, C.1
Larocque, E.2
Landry, S.3
-
54
-
-
84873709314
-
Identification of a candidate therapeutic autophagy-inducing peptide
-
Shoji-Kawata S, Sumpter R, Leveno M et al. Identification of a candidate therapeutic autophagy-inducing peptide. Nature 2013; 494: 201–6.
-
(2013)
Nature
, vol.494
, pp. 201-206
-
-
Shoji-Kawata, S.1
Sumpter, R.2
Leveno, M.3
-
55
-
-
84936742816
-
Human immunodeficiency virus type 1 nef inhibits autophagy through transcription factor EB sequestration
-
Campbell GR, Rawat P, Bruckman RS, Spector SA. Human immunodeficiency virus type 1 nef inhibits autophagy through transcription factor EB sequestration. PLoS Pathog 2015; 11: e1005018.
-
(2015)
PLoS Pathog
, vol.11
-
-
Campbell, G.R.1
Rawat, P.2
Bruckman, R.S.3
Spector, S.A.4
-
56
-
-
84927561935
-
HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy
-
Borel S, Robert-Hebmann V, Alfaisal J et al. HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy. AIDS 2015; 29: 275–86.
-
(2015)
AIDS
, vol.29
, pp. 275-286
-
-
Borel, S.1
Robert-Hebmann, V.2
Alfaisal, J.3
-
57
-
-
84855998457
-
Global landscape of HIV-human protein complexes
-
Jager S, Cimermancic P, Gulbahce N et al. Global landscape of HIV-human protein complexes. Nature 2011; 481: 365–70.
-
(2011)
Nature
, vol.481
, pp. 365-370
-
-
Jager, S.1
Cimermancic, P.2
Gulbahce, N.3
-
58
-
-
84907599058
-
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
-
Mandell MA, Jain A, Arko-Mensah J et al. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Dev Cell 2014; 30: 394–409.
-
(2014)
Dev Cell
, vol.30
, pp. 394-409
-
-
Mandell, M.A.1
Jain, A.2
Arko-Mensah, J.3
-
59
-
-
84935037656
-
The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation
-
Valera MS, de Armas-Rillo L, Barroso-Gonzalez J et al. The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation. Retrovirology 2015; 12: 53.
-
(2015)
Retrovirology
, vol.12
, pp. 53
-
-
Valera, M.S.1
de Armas-Rillo, L.2
Barroso-Gonzalez, J.3
-
60
-
-
84919414166
-
Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes
-
Sagnier S, Daussy CF, Borel S et al. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. J Virol 2015; 89: 615–25.
-
(2015)
J Virol
, vol.89
, pp. 615-625
-
-
Sagnier, S.1
Daussy, C.F.2
Borel, S.3
-
61
-
-
66749170589
-
Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV-1 infection
-
Espert L, Varbanov M, Robert-Hebmann V et al. Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV-1 infection. PLoS One 2009; 4: e5787.
-
(2009)
PLoS One
, vol.4
-
-
Espert, L.1
Varbanov, M.2
Robert-Hebmann, V.3
-
62
-
-
84867250039
-
Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1
-
Campbell GR, Spector SA. Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1. Autophagy 2012; 8: 1523–5.
-
(2012)
Autophagy
, vol.8
, pp. 1523-1525
-
-
Campbell, G.R.1
Spector, S.A.2
-
63
-
-
84863714328
-
Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy
-
Campbell GR, Spector SA. Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy. PLoS Pathog 2012; 8: e1002689.
-
(2012)
PLoS Pathog
, vol.8
-
-
Campbell, G.R.1
Spector, S.A.2
-
64
-
-
84903827389
-
Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients
-
Nardacci R, Amendola A, Ciccosanti F et al. Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients. Autophagy 2014; 10: 1167–78.
-
(2014)
Autophagy
, vol.10
, pp. 1167-1178
-
-
Nardacci, R.1
Amendola, A.2
Ciccosanti, F.3
-
65
-
-
13244260955
-
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope
-
Perfettini JL, Castedo M, Nardacci R et al. Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med 2005; 201: 279–89.
-
(2005)
J Exp Med
, vol.201
, pp. 279-289
-
-
Perfettini, J.L.1
Castedo, M.2
Nardacci, R.3
-
66
-
-
22744435902
-
Mechanisms of apoptosis induction by the HIV-1 envelope
-
Perfettini JL, Castedo M, Roumier T et al. Mechanisms of apoptosis induction by the HIV-1 envelope. Cell Death Differ 2005; 12(Suppl 1): 916–23.
-
(2005)
Cell Death Differ
, vol.12
, pp. 916-923
-
-
Perfettini, J.L.1
Castedo, M.2
Roumier, T.3
-
67
-
-
33746691954
-
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
-
Espert L, Denizot M, Grimaldi M et al. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest 2006; 116: 2161–72.
-
(2006)
J Clin Invest
, vol.116
, pp. 2161-2172
-
-
Espert, L.1
Denizot, M.2
Grimaldi, M.3
-
68
-
-
58149083753
-
HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells
-
Denizot M, Varbanov M, Espert L et al. HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells. Autophagy 2008; 4: 998–1008.
-
(2008)
Autophagy
, vol.4
, pp. 998-1008
-
-
Denizot, M.1
Varbanov, M.2
Espert, L.3
-
69
-
-
84878487502
-
DRAM triggers lysosomal membrane permeabilization and cell death in CD4(+) T cells infected with HIV
-
Laforge M, Limou S, Harper F et al. DRAM triggers lysosomal membrane permeabilization and cell death in CD4(+) T cells infected with HIV. PLoS Pathog 2013; 9: e1003328.
-
(2013)
PLoS Pathog
, vol.9
-
-
Laforge, M.1
Limou, S.2
Harper, F.3
-
70
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
-
Doitsh G, Galloway NL, Geng X et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature 2014; 505: 509–14.
-
(2014)
Nature
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
Galloway, N.L.2
Geng, X.3
-
71
-
-
84892946076
-
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV
-
Monroe KM, Yang Z, Johnson JR et al. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science 2014; 343: 428–32.
-
(2014)
Science
, vol.343
, pp. 428-432
-
-
Monroe, K.M.1
Yang, Z.2
Johnson, J.R.3
-
72
-
-
53849134844
-
Cellular reservoirs of HIV-1 and their role in viral persistence
-
Alexaki A, Liu Y, Wigdahl B. Cellular reservoirs of HIV-1 and their role in viral persistence. Curr HIV Res 2008; 6: 388–400.
-
(2008)
Curr HIV Res
, vol.6
, pp. 388-400
-
-
Alexaki, A.1
Liu, Y.2
Wigdahl, B.3
-
73
-
-
77955375856
-
HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3
-
Van Grol J, Subauste C, Andrade RM, Fujinaga K, Nelson J, Subauste CS. HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3. PLoS One 2010; 5: e11733.
-
(2010)
PLoS One
, vol.5
-
-
Van Grol, J.1
Subauste, C.2
Andrade, R.M.3
Fujinaga, K.4
Nelson, J.5
Subauste, C.S.6
-
74
-
-
84894435407
-
Dendritic cells in progression and pathology of HIV infection
-
Manches O, Frleta D, Bhardwaj N. Dendritic cells in progression and pathology of HIV infection. Trends Immunol 2014; 35: 114–22.
-
(2014)
Trends Immunol
, vol.35
, pp. 114-122
-
-
Manches, O.1
Frleta, D.2
Bhardwaj, N.3
-
75
-
-
77953272740
-
Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses
-
Blanchet FP, Moris A, Nikolic DS et al. Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity 2010; 32: 654–69.
-
(2010)
Immunity
, vol.32
, pp. 654-669
-
-
Blanchet, F.P.1
Moris, A.2
Nikolic, D.S.3
-
76
-
-
67651065500
-
HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase
-
Harman AN, Kraus M, Bye CR et al. HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Blood 2009; 114: 85–94.
-
(2009)
Blood
, vol.114
, pp. 85-94
-
-
Harman, A.N.1
Kraus, M.2
Bye, C.R.3
-
77
-
-
84859061111
-
Production of interferon alpha by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy
-
Zhou D, Kang KH, Spector SA. Production of interferon alpha by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy. J Infect Dis 2012; 205: 1258–67.
-
(2012)
J Infect Dis
, vol.205
, pp. 1258-1267
-
-
Zhou, D.1
Kang, K.H.2
Spector, S.A.3
-
78
-
-
84960364100
-
HIV-associated neurocognitive disorder–pathogenesis and prospects for treatment
-
Saylor D, Dickens AM, Sacktor N et al. HIV-associated neurocognitive disorder–pathogenesis and prospects for treatment. Nat Rev Neurol 2016; 12: 234–48.
-
(2016)
Nat Rev Neurol
, vol.12
, pp. 234-248
-
-
Saylor, D.1
Dickens, A.M.2
Sacktor, N.3
-
79
-
-
79956204926
-
Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis
-
Zhou D, Masliah E, Spector SA. Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis. J Infect Dis 2011; 203: 1647–57.
-
(2011)
J Infect Dis
, vol.203
, pp. 1647-1657
-
-
Zhou, D.1
Masliah, E.2
Spector, S.A.3
-
80
-
-
84891373653
-
Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders
-
Fields J, Dumaop W, Adame A et al. Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders. J Neuroimmune Pharmacol 2013; 8: 1197–209.
-
(2013)
J Neuroimmune Pharmacol
, vol.8
, pp. 1197-1209
-
-
Fields, J.1
Dumaop, W.2
Adame, A.3
-
81
-
-
51449119611
-
Disruption of neuronal autophagy by infected microglia results in neurodegeneration
-
Alirezaei M, Kiosses WB, Flynn CT, Brady NR, Fox HS. Disruption of neuronal autophagy by infected microglia results in neurodegeneration. PLoS One 2008; 3: e2906.
-
(2008)
PLoS One
, vol.3
-
-
Alirezaei, M.1
Kiosses, W.B.2
Flynn, C.T.3
Brady, N.R.4
Fox, H.S.5
-
82
-
-
84890484713
-
Roles and functions of HIV-1 Tat protein in the CNS: an overview
-
Bagashev A, Sawaya BE. Roles and functions of HIV-1 Tat protein in the CNS: an overview. Virol J 2013; 10: 358.
-
(2013)
Virol J
, vol.10
, pp. 358
-
-
Bagashev, A.1
Sawaya, B.E.2
-
84
-
-
84867592757
-
Role of endolysosomes in HIV-1 Tat-induced neurotoxicity
-
Hui L, Chen X, Haughey NJ, Geiger JD. Role of endolysosomes in HIV-1 Tat-induced neurotoxicity. ASN Neuro 2012; 4: 243–52.
-
(2012)
ASN Neuro
, vol.4
, pp. 243-252
-
-
Hui, L.1
Chen, X.2
Haughey, N.J.3
Geiger, J.D.4
-
85
-
-
84881230027
-
HIV associated neurocognitive disorders
-
Zhou L, Saksena NK. HIV associated neurocognitive disorders. Infect Dis Rep 2013; 5: e8.
-
(2013)
Infect Dis Rep
, vol.5
-
-
Zhou, L.1
Saksena, N.K.2
-
86
-
-
84920618618
-
HIV-1 Tat protein induces glial cell autophagy through enhancement of BAG3 protein levels
-
Bruno AP, De Simone FI, Iorio V et al. HIV-1 Tat protein induces glial cell autophagy through enhancement of BAG3 protein levels. Cell Cycle 2014; 13: 3640–4.
-
(2014)
Cell Cycle
, vol.13
, pp. 3640-3644
-
-
Bruno, A.P.1
De Simone, F.I.2
Iorio, V.3
-
87
-
-
84953924222
-
Dysregulation of autophagy by HIV-1 Nef in human astrocytes
-
Saribas AS, Khalili K, Sariyer IK. Dysregulation of autophagy by HIV-1 Nef in human astrocytes. Cell Cycle 2015; 14: 2899–904.
-
(2015)
Cell Cycle
, vol.14
, pp. 2899-2904
-
-
Saribas, A.S.1
Khalili, K.2
Sariyer, I.K.3
-
88
-
-
77949908335
-
First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation
-
Di Benedetto F, Di Sandro S, De Ruvo N et al. First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation. Transplantation 2010; 89: 733–8.
-
(2010)
Transplantation
, vol.89
, pp. 733-738
-
-
Di Benedetto, F.1
Di Sandro, S.2
De Ruvo, N.3
-
89
-
-
84995897838
-
High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy
-
Gangcuangco LM, Kohorn LB, Chow DC et al. High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy. Medicine (Baltimore) 2016; 95: e5270.
-
(2016)
Medicine (Baltimore)
, vol.95
-
-
Gangcuangco, L.M.1
Kohorn, L.B.2
Chow, D.C.3
-
90
-
-
84929094317
-
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1
-
Campbell GR, Bruckman RS, Chu YL, Spector SA. Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1. J Biol Chem 2015; 290: 5028–40.
-
(2015)
J Biol Chem
, vol.290
, pp. 5028-5040
-
-
Campbell, G.R.1
Bruckman, R.S.2
Chu, Y.L.3
Spector, S.A.4
-
91
-
-
4143089463
-
Administration of HDAC inhibitors to reactivate HIV-1 expression in latent cellular reservoirs: implications for the development of therapeutic strategies
-
Demonte D, Quivy V, Colette Y, Van Lint C. Administration of HDAC inhibitors to reactivate HIV-1 expression in latent cellular reservoirs: implications for the development of therapeutic strategies. Biochem Pharmacol 2004; 68: 1231–8.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1231-1238
-
-
Demonte, D.1
Quivy, V.2
Colette, Y.3
Van Lint, C.4
-
92
-
-
84946043481
-
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
-
Chauhan S, Ahmed Z, Bradfute SB et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun 2015; 6: 8620.
-
(2015)
Nat Commun
, vol.6
, pp. 8620
-
-
Chauhan, S.1
Ahmed, Z.2
Bradfute, S.B.3
-
93
-
-
0036952736
-
Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe
-
Castedo M, Perfettini JL, Roumier T, Kroemer G. Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe. Cell Death Differ 2002; 9: 1287–93.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1287-1293
-
-
Castedo, M.1
Perfettini, J.L.2
Roumier, T.3
Kroemer, G.4
|