MTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

Nature Cell Biology

Volumn 15, Issue 4, 2013, Pages 406-416

  Nazio, Francesca ^a,b   Strappazzon, Flavie ^a,b   Antonioli, Manuela ^c   Bielli, Pamela ^b   Cianfanelli, Valentina ^a,b   Bordi, Matteo ^a,b   Gretzmeier, Christine ^d   Dengjel, Joern ^d   Piacentini, Mauro ^a,c   Fimia, Gian Maria ^c   Cecconi, Francesco ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMBRA1 PROTEIN; LYSINE; MAMMALIAN TARGET OF RAPAMYCIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; ULK1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AUTOPHAGY; BLOTTING, WESTERN; CELLS, CULTURED; HELA CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOR SERINE-THREONINE KINASES; UBIQUITINATION;

MAMMALIA;

EID: 84876488191     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2708     Document Type: Article

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