메뉴 건너뛰기




Volumn 16, Issue 7, 2016, Pages 1988-2002

TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy

Author keywords

AIM2 inflammasome; p62; protein degradation; selective autophagy; TRIM11

Indexed keywords

ABSENT IN MELANOMA 2 PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; LYSINE; PEPTIDES AND PROTEINS; PROTEIN P62; TRIPARTITE MOTIF PROTEIN 11; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; AIM2 PROTEIN, HUMAN; DNA BINDING PROTEIN; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN BINDING; SEQUESTOSOME 1; SQSTM1 PROTEIN, HUMAN; TRIM11 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 84997830946     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.07.019     Document Type: Article
Times cited : (141)

References (38)
  • 3
    • 84920547918 scopus 로고    scopus 로고
    • Response of host inflammasomes to viral infection
    • Chen, I.Y., Ichinohe, T., Response of host inflammasomes to viral infection. Trends Microbiol. 23 (2015), 55–63.
    • (2015) Trends Microbiol. , vol.23 , pp. 55-63
    • Chen, I.Y.1    Ichinohe, T.2
  • 4
    • 77955352128 scopus 로고    scopus 로고
    • Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
    • Fan, W., Tang, Z., Chen, D., Moughon, D., Ding, X., Chen, S., Zhu, M., Zhong, Q., Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy. Autophagy 6 (2010), 614–621.
    • (2010) Autophagy , vol.6 , pp. 614-621
    • Fan, W.1    Tang, Z.2    Chen, D.3    Moughon, D.4    Ding, X.5    Chen, S.6    Zhu, M.7    Zhong, Q.8
  • 5
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri, T., Yu, J.W., Datta, P., Wu, J., Alnemri, E.S., AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458 (2009), 509–513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 7
    • 84890018924 scopus 로고    scopus 로고
    • Autophagy-mediated tumor promotion
    • Guo, J.Y., Xia, B., White, E., Autophagy-mediated tumor promotion. Cell 155 (2013), 1216–1219.
    • (2013) Cell , vol.155 , pp. 1216-1219
    • Guo, J.Y.1    Xia, B.2    White, E.3
  • 10
    • 78650636576 scopus 로고    scopus 로고
    • Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production
    • Hu, Y., Mao, K., Zeng, Y., Chen, S., Tao, Z., Yang, C., Sun, S., Wu, X., Meng, G., Sun, B., Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. J. Immunol. 185 (2010), 7699–7705.
    • (2010) J. Immunol. , vol.185 , pp. 7699-7705
    • Hu, Y.1    Mao, K.2    Zeng, Y.3    Chen, S.4    Tao, Z.5    Yang, C.6    Sun, S.7    Wu, X.8    Meng, G.9    Sun, B.10
  • 11
    • 84964304860 scopus 로고    scopus 로고
    • Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1
    • Jia, W., He, M.X., McLeod, I.X., Guo, J., Ji, D., He, Y.W., Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1. Autophagy 11 (2015), 2335–2345.
    • (2015) Autophagy , vol.11 , pp. 2335-2345
    • Jia, W.1    He, M.X.2    McLeod, I.X.3    Guo, J.4    Ji, D.5    He, Y.W.6
  • 12
    • 84859986329 scopus 로고    scopus 로고
    • Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor
    • Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J.A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V.A., Johnstone, R.W., et al. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity 36 (2012), 561–571.
    • (2012) Immunity , vol.36 , pp. 561-571
    • Jin, T.1    Perry, A.2    Jiang, J.3    Smith, P.4    Curry, J.A.5    Unterholzner, L.6    Jiang, Z.7    Horvath, G.8    Rathinam, V.A.9    Johnstone, R.W.10
  • 13
    • 84961219291 scopus 로고    scopus 로고
    • USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin-1
    • Jin, S., Tian, S., Chen, Y., Zhang, C., Xie, W., Xia, X., Cui, J., Wang, R.F., USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin-1. EMBO J. 35 (2016), 866–880.
    • (2016) EMBO J. , vol.35 , pp. 866-880
    • Jin, S.1    Tian, S.2    Chen, Y.3    Zhang, C.4    Xie, W.5    Xia, X.6    Cui, J.7    Wang, R.F.8
  • 14
    • 79952355107 scopus 로고    scopus 로고
    • Selective autophagy mediated by autophagic adapter proteins
    • Johansen, T., Lamark, T., Selective autophagy mediated by autophagic adapter proteins. Autophagy 7 (2011), 279–296.
    • (2011) Autophagy , vol.7 , pp. 279-296
    • Johansen, T.1    Lamark, T.2
  • 16
    • 85019556441 scopus 로고    scopus 로고
    • TRIM-directed selective autophagy regulates immune activation
    • Published online March 16, 2016
    • Kimura, T., Jain, A., Choi, S.W., Mandell, M.A., Johansen, T., Deretic, V., TRIM-directed selective autophagy regulates immune activation. Autophagy, 2016, 10.1080/15548627.2016.1154254 Published online March 16, 2016.
    • (2016) Autophagy
    • Kimura, T.1    Jain, A.2    Choi, S.W.3    Mandell, M.A.4    Johansen, T.5    Deretic, V.6
  • 17
    • 69849101245 scopus 로고    scopus 로고
    • AIMing 2 detect foreign DNA
    • Krieg, A.M., AIMing 2 detect foreign DNA. Sci Signal, 2, 2009, pe39.
    • (2009) Sci Signal , vol.2 , pp. pe39
    • Krieg, A.M.1
  • 18
    • 0032130971 scopus 로고    scopus 로고
    • The Ifi 200 genes: an emerging family of IFN-inducible genes
    • Landolfo, S., Gariglio, M., Gribaudo, G., Lembo, D., The Ifi 200 genes: an emerging family of IFN-inducible genes. Biochimie 80 (1998), 721–728.
    • (1998) Biochimie , vol.80 , pp. 721-728
    • Landolfo, S.1    Gariglio, M.2    Gribaudo, G.3    Lembo, D.4
  • 19
    • 84878237993 scopus 로고    scopus 로고
    • Activation and regulation of the inflammasomes
    • Latz, E., Xiao, T.S., Stutz, A., Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13 (2013), 397–411.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 397-411
    • Latz, E.1    Xiao, T.S.2    Stutz, A.3
  • 21
    • 84964304883 scopus 로고    scopus 로고
    • TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction
    • Mandell, M.A., Kimura, T., Jain, A., Johansen, T., Deretic, V., TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy 10 (2014), 2387–2388.
    • (2014) Autophagy , vol.10 , pp. 2387-2388
    • Mandell, M.A.1    Kimura, T.2    Jain, A.3    Johansen, T.4    Deretic, V.5
  • 22
    • 82455172117 scopus 로고    scopus 로고
    • Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins
    • Matsumoto, G., Wada, K., Okuno, M., Kurosawa, M., Nukina, N., Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Mol. Cell 44 (2011), 279–289.
    • (2011) Mol. Cell , vol.44 , pp. 279-289
    • Matsumoto, G.1    Wada, K.2    Okuno, M.3    Kurosawa, M.4    Nukina, N.5
  • 23
    • 84959386443 scopus 로고    scopus 로고
    • Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch
    • Meng, Q., Cai, C., Sun, T., Wang, Q., Xie, W., Wang, R., Cui, J., Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch. J. Cell Biol. 211 (2015), 1025–1040.
    • (2015) J. Cell Biol. , vol.211 , pp. 1025-1040
    • Meng, Q.1    Cai, C.2    Sun, T.3    Wang, Q.4    Xie, W.5    Wang, R.6    Cui, J.7
  • 24
    • 84878190840 scopus 로고    scopus 로고
    • Immune sensing of DNA
    • Paludan, S.R., Bowie, A.G., Immune sensing of DNA. Immunity 38 (2013), 870–880.
    • (2013) Immunity , vol.38 , pp. 870-880
    • Paludan, S.R.1    Bowie, A.G.2
  • 25
    • 84872782298 scopus 로고    scopus 로고
    • Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
    • Py, B.F., Kim, M.S., Vakifahmetoglu-Norberg, H., Yuan, J., Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol. Cell 49 (2013), 331–338.
    • (2013) Mol. Cell , vol.49 , pp. 331-338
    • Py, B.F.1    Kim, M.S.2    Vakifahmetoglu-Norberg, H.3    Yuan, J.4
  • 28
    • 84896354710 scopus 로고    scopus 로고
    • Inflammasome: putting the pieces together
    • Ruland, J., Inflammasome: putting the pieces together. Cell 156 (2014), 1127–1129.
    • (2014) Cell , vol.156 , pp. 1127-1129
    • Ruland, J.1
  • 31
    • 84891470536 scopus 로고    scopus 로고
    • Role of the HIN domain in regulation of innate immune responses
    • Shaw, N., Liu, Z.J., Role of the HIN domain in regulation of innate immune responses. Mol. Cell. Biol. 34 (2014), 2–15.
    • (2014) Mol. Cell. Biol. , vol.34 , pp. 2-15
    • Shaw, N.1    Liu, Z.J.2
  • 32
    • 84857195479 scopus 로고    scopus 로고
    • Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
    • Shi, C.S., Shenderov, K., Huang, N.N., Kabat, J., Abu-Asab, M., Fitzgerald, K.A., Sher, A., Kehrl, J.H., Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 13 (2012), 255–263.
    • (2012) Nat. Immunol. , vol.13 , pp. 255-263
    • Shi, C.S.1    Shenderov, K.2    Huang, N.N.3    Kabat, J.4    Abu-Asab, M.5    Fitzgerald, K.A.6    Sher, A.7    Kehrl, J.H.8
  • 33
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339 (2013), 786–791.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.J.5
  • 35
    • 77951208421 scopus 로고    scopus 로고
    • TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies
    • Tanji, K., Kamitani, T., Mori, F., Kakita, A., Takahashi, H., Wakabayashi, K., TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies. Neurobiol. Dis. 38 (2010), 210–218.
    • (2010) Neurobiol. Dis. , vol.38 , pp. 210-218
    • Tanji, K.1    Kamitani, T.2    Mori, F.3    Kakita, A.4    Takahashi, H.5    Wakabayashi, K.6
  • 36
    • 84901036068 scopus 로고    scopus 로고
    • Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin
    • Walinda, E., Morimoto, D., Sugase, K., Konuma, T., Tochio, H., Shirakawa, M., Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin. J. Biol. Chem. 289 (2014), 13890–13902.
    • (2014) J. Biol. Chem. , vol.289 , pp. 13890-13902
    • Walinda, E.1    Morimoto, D.2    Sugase, K.3    Konuma, T.4    Tochio, H.5    Shirakawa, M.6
  • 38
    • 84927699710 scopus 로고    scopus 로고
    • The nucleic acid-sensing inflammasomes
    • Xiao, T.S., The nucleic acid-sensing inflammasomes. Immunol. Rev. 265 (2015), 103–111.
    • (2015) Immunol. Rev. , vol.265 , pp. 103-111
    • Xiao, T.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.