Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

PLoS Pathogens

Volumn 11, Issue 6, 2015, Pages

  Campbell, Grant R ^a   Rawat, Pratima ^a   Bruckman, Rachel S ^a   Spector, Stephen A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MATURATION PROMOTING FACTOR; NEF PROTEIN; TOLL LIKE RECEPTOR 8; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BECN1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, HUMAN; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; TARGET OF RAPAMYCIN KINASE; TFEB PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; BLOOD ANALYSIS; CELL CULTURE; CONTROLLED STUDY; DEPHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; MACROPHAGE; MICROSCOPY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION; IMMUNOLOGY; METABOLISM; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA;

APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BECLIN-1; HIV-1; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TOLL-LIKE RECEPTOR 8; TOR SERINE-THREONINE KINASES; VIRUS REPLICATION;

EID: 84936742816     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005018     Document Type: Article

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