Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution

Science

Volumn 355, Issue 6328, 2017, Pages

  Shen, Huaizong ^a   Zhou, Qiang ^a,b   Pan, Xiaojing ^a   Li, Zhangqiang ^a,b   Wu, Jianping ^a,b   Yan, Nieng ^a,b  

^a TSINGHUA UNIVERSITY   (China)

^b Tsinghua University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPEPTIDE; VOLTAGE GATED SODIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT;

CALCIUM; CHEMICAL BONDING; COCKROACH; CYTOPLASM; DISEASE INCIDENCE; DRUG; ELECTRON MICROSCOPY; EUKARYOTE; SODIUM; TOXIN;

ACTION POTENTIAL; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL COMPOSITION; CHO CELL LINE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DISULFIDE BOND; EXCITATION CONTRACTION COUPLING; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE; PERIPLANETA AMERICANA; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; TRANSIENT EXPRESSION; X RAY CRYSTALLOGRAPHY; XENOPUS LAEVIS; ANIMAL; CHEMICAL MODEL; CHEMISTRY; CONSERVED SEQUENCE; PERIPLANETA; PROTEIN DOMAIN; ULTRASTRUCTURE;

EUKARYOTA; PERIPLANETA AMERICANA;

ANIMALS; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; GLYCOSYLATION; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MODELS, CHEMICAL; PERIPLANETA; PROTEIN DOMAINS; VOLTAGE-GATED SODIUM CHANNELS;

EID: 85013031896     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aal4326     Document Type: Article

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