Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Bourdin, Céline M ^a   Moignot, Bénédicte ^a   Wang, Lingxin ^b   Murillo, Laurence ^a,c   Juchaux, Marjorie ^d   Quinchard, Sophie ^a   Lapied, Bruno ^a   Guérineau, Nathalie C ^e   Dong, Ke ^b   Legros, Christian ^a,e  

^a UNIVERSITÉ D'ANGERS   (France)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITÉ DE LA ROCHELLE   (France)

^d UNIVERSITÉ D'ANGERS   (France)

^e Universite d'Angers   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; MESSENGER RNA; SODIUM CHANNEL NAV1.1; VOLTAGE GATED SODIUM CHANNEL;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ARTICLE; BIOPHYSICS; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DRUG SENSITIVITY; ELECTRIC POTENTIAL; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYDROPHOBICITY; INTRON; MALE; MOLECULAR CLONING; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PERIPLANETA AMERICANA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SENSOR; SINGLE BICISTRONIC GENE; TEH1 GENE; TEH1A GENE; TEH1B GENE; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA, COMPLEMENTARY; INSECTS; INTRONS; MALE; MOLECULAR SEQUENCE DATA; OOCYTES; ORGAN SPECIFICITY; PROTEIN SUBUNITS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SODIUM; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS; VOLTAGE-GATED SODIUM CHANNELS; XENOPUS;

EID: 84881573183     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067290     Document Type: Article

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